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Accession:CHEBI:83499 term browser browse the term
Definition:A racemate composed of equimolar amounts of (R)- and (S)-climbazole. It is a topically applied antifungal agent used to treat human fungal skin infections.
Synonyms:exact_synonym: rac-1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one
 related_synonym: (RS)-1-(4-chlorophenoxy)-1-imidazol-1-yl-3,3-dimethylbutan-2-one;   1-(p-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethyl -2-butanone;   Climbazolum;   Formula=C15H17ClN2O2;   climbazol
 xref: CAS:38083-17-9
 xref_mesh: MESH:C108286
 xref: PMID:11552297;   PMID:11824557;   PMID:18950734;   PMID:21272039;   PMID:23542433;   PMID:23958691;   PMID:23982925;   PMID:24811958;   PMID:25794970;   PMID:27378240;   Patent:DE102012203240;   Pesticides:climbazole;   Reaxys:618020;   Wikipedia:Climbazole

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climbazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 JBrowse link 7 99,142,431 99,183,540 RGD:6480464
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 JBrowse link 12 11,641,500 11,677,818 RGD:6480464
G Cyp4a1 cytochrome P450, family 4, subfamily a, polypeptide 1 JBrowse link 5 134,492,734 134,507,158 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19770
    role 19717
      biological role 19716
        xenobiotic 18398
          climbazole 3
Path 2
Term Annotations click to browse term
  CHEBI ontology 19770
    subatomic particle 19768
      composite particle 19768
        hadron 19768
          baryon 19768
            nucleon 19768
              atomic nucleus 19768
                atom 19768
                  main group element atom 19655
                    main group molecular entity 19655
                      s-block molecular entity 19398
                        hydrogen molecular entity 19388
                          hydrides 18363
                            inorganic hydride 17213
                              pnictogen hydride 17176
                                nitrogen hydride 17011
                                  azane 16704
                                    ammonia 16703
                                      organic amino compound 16702
                                        hemiaminal 459
                                          hemiaminal ether 387
                                            1-(4-chlorophenoxy)-1-(1H-imidazol-1-yl)-3,3-dimethylbutan-2-one 3
                                              (R)-climbazole 3
                                                climbazole 3
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.