Qki (QKI, KH domain containing RNA binding) - Rat Genome Database

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Gene: Qki (QKI, KH domain containing RNA binding) Rattus norvegicus
Analyze
Symbol: Qki
Name: QKI, KH domain containing RNA binding
RGD ID: 1584886
Description: Predicted to enable mRNA binding activity. Involved in several processes, including mRNA stabilization; negative regulation of cardiac muscle cell apoptotic process; and positive regulation of oligodendrocyte differentiation. Located in nucleus. Orthologous to human QKI (QKI, KH domain containing RNA binding); PARTICIPATES IN spliceosome pathway; INTERACTS WITH 6-propyl-2-thiouracil; ammonium chloride; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: homolog of mouse quaking QKI (KH domain RNA binding protein); LOC108348175; LOC499022; LOW QUALITY PROTEIN: protein quaking-like; MGC188205; protein quaking; protein quaking-like; Qk; quaking; quaking homolog, KH domain RNA binding (mouse); quaking, KH domain containing RNA binding; rqkI; similar to quaking homolog, KH domain RNA binding isoform HQK-6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2150,387,698 - 50,501,568 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl150,387,698 - 50,498,831 (+)Ensembl
Rnor_6.0150,983,647 - 51,050,692 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl150,828,134 - 51,052,340 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0152,104,976 - 52,207,885 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4144,922,562 - 45,025,572 (+)NCBIRGSC3.4rn4RGSC3.4
Celera146,204,164 - 46,271,210 (+)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
6-propyl-2-thiouracil  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
haloperidol  (ISO)
isotretinoin  (ISO)
ivermectin  (ISO)
kainic acid  (ISO)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
miconazole  (ISO)
N-ethyl-N-nitrosourea  (ISO)
nicotine  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
propiconazole  (ISO)
raloxifene  (ISO)
resveratrol  (EXP)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
topotecan  (ISO)
trichostatin A  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:1150661   PMID:1373175   PMID:10506177   PMID:11178867   PMID:11892011   PMID:12477932   PMID:14169723   PMID:14706070   PMID:15057822   PMID:15148410   PMID:15568022   PMID:15632090  
PMID:16452087   PMID:19517016   PMID:22681889   PMID:22871113   PMID:25145264  


Genomics

Comparative Map Data
Qki
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2150,387,698 - 50,501,568 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl150,387,698 - 50,498,831 (+)Ensembl
Rnor_6.0150,983,647 - 51,050,692 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl150,828,134 - 51,052,340 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0152,104,976 - 52,207,885 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4144,922,562 - 45,025,572 (+)NCBIRGSC3.4rn4RGSC3.4
Celera146,204,164 - 46,271,210 (+)NCBICelera
Cytogenetic Map1q11NCBI
QKI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386163,414,718 - 163,578,592 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl6163,414,000 - 163,578,592 (+)EnsemblGRCh38hg38GRCh38
GRCh376163,835,750 - 163,999,624 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366163,755,665 - 163,914,886 (+)NCBINCBI36hg18NCBI36
Celera6164,606,149 - 164,729,418 (+)NCBI
Cytogenetic Map6q26NCBI
HuRef6161,290,590 - 161,453,987 (+)NCBIHuRef
CHM1_16164,097,893 - 164,261,842 (+)NCBICHM1_1
Qki
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391710,425,400 - 10,538,706 (-)NCBIGRCm39mm39
GRCm39 Ensembl1710,421,530 - 10,538,783 (-)Ensembl
GRCm381710,206,471 - 10,319,361 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1710,202,601 - 10,319,854 (-)EnsemblGRCm38mm10GRCm38
MGSCv371710,399,336 - 10,512,226 (-)NCBIGRCm37mm9NCBIm37
MGSCv361710,053,536 - 10,163,211 (-)NCBImm8
Celera1710,252,038 - 10,337,960 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map177.75NCBI
Qki
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543917,925,229 - 18,079,727 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543917,925,205 - 18,079,727 (-)NCBIChiLan1.0ChiLan1.0
QKI
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.16166,398,884 - 166,517,389 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v06161,361,413 - 161,523,414 (+)NCBIMhudiblu_PPA_v0panPan3
QKI
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1151,800,294 - 51,956,891 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl151,800,309 - 51,952,714 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha152,642,145 - 52,797,414 (+)NCBI
ROS_Cfam_1.0151,975,526 - 52,138,964 (+)NCBI
ROS_Cfam_1.0 Ensembl151,977,027 - 52,136,022 (+)Ensembl
UMICH_Zoey_3.1151,867,832 - 52,023,107 (+)NCBI
UNSW_CanFamBas_1.0151,727,887 - 51,883,146 (+)NCBI
UU_Cfam_GSD_1.0152,356,356 - 52,511,535 (+)NCBI
Qki
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946146,649,733 - 146,750,270 (+)NCBI
SpeTri2.0NW_00493648913,901,066 - 14,000,652 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
QKI
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14,735,513 - 4,883,768 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114,732,575 - 4,883,386 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.216,380,698 - 6,486,326 (-)NCBISscrofa10.2Sscrofa10.2susScr3
QKI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11391,045,167 - 91,206,190 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl1391,045,209 - 91,208,471 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604062,921,663 - 63,087,940 (+)NCBIVero_WHO_p1.0
Qki
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462478515,738,231 - 15,845,051 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BE111947  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2150,497,903 - 50,498,053 (+)MAPPERmRatBN7.2
Rnor_6.0151,057,439 - 51,057,588NCBIRnor6.0
Rnor_5.0152,333,742 - 52,333,891UniSTSRnor5.0
RGSC_v3.4145,032,319 - 45,032,468UniSTSRGSC3.4
Celera146,277,965 - 46,278,114UniSTS
RH 3.4 Map1593.4UniSTS
Cytogenetic Map1q11UniSTS
QKI  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2150,489,724 - 50,489,961 (+)MAPPERmRatBN7.2
Rnor_6.0151,049,261 - 51,049,497NCBIRnor6.0
Rnor_6.0150,930,151 - 50,930,387NCBIRnor6.0
Rnor_5.0152,206,454 - 52,206,690UniSTSRnor5.0
Rnor_5.0152,325,564 - 52,325,800UniSTSRnor5.0
RGSC_v3.4145,024,141 - 45,024,377UniSTSRGSC3.4
Celera146,269,779 - 46,270,015UniSTS
Cytogenetic Map1q11UniSTS
BF394556  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2150,409,623 - 50,409,858 (+)MAPPERmRatBN7.2
Rnor_6.0150,850,065 - 50,850,299NCBIRnor6.0
Rnor_6.0150,968,974 - 50,969,208NCBIRnor6.0
Rnor_5.0152,245,277 - 52,245,511UniSTSRnor5.0
Rnor_5.0152,126,368 - 52,126,602UniSTSRnor5.0
RGSC_v3.4144,944,055 - 44,944,289UniSTSRGSC3.4
Celera146,189,690 - 46,189,924UniSTS
RH 3.4 Map1594.3UniSTS
Cytogenetic Map1q11UniSTS
Qk  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0150,828,594 - 50,828,711NCBIRnor6.0
RGSC_v3.4144,922,583 - 44,922,701UniSTSRGSC3.4
Cytogenetic Map1q11UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)11148131282174945Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)cortical volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889962Bss94Bone structure and strength QTL 943.8tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)14936146582174945Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:614
Count of miRNA genes:229
Interacting mature miRNAs:276
Transcripts:ENSRNOT00000023290, ENSRNOT00000023304, ENSRNOT00000035402, ENSRNOT00000071865
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000023290   ⟹   ENSRNOP00000023290
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl150,387,698 - 50,492,371 (+)Ensembl
Rnor_6.0 Ensembl150,828,585 - 51,050,257 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000035402   ⟹   ENSRNOP00000034413
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl150,387,698 - 50,493,096 (+)Ensembl
Rnor_6.0 Ensembl150,828,585 - 51,052,340 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000086441   ⟹   ENSRNOP00000070460
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl150,388,120 - 50,498,831 (+)Ensembl
Rnor_6.0 Ensembl150,828,585 - 50,933,516 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089149   ⟹   ENSRNOP00000069203
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl150,387,698 - 50,491,151 (+)Ensembl
Rnor_6.0 Ensembl150,828,134 - 50,931,579 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099441   ⟹   ENSRNOP00000096216
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl150,387,698 - 50,497,836 (+)Ensembl
RefSeq Acc Id: NM_001115021   ⟹   NP_001108493
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,698 - 50,491,156 (+)NCBI
Rnor_6.0150,983,647 - 51,050,692 (+)NCBI
Rnor_5.0152,104,976 - 52,207,885 (+)NCBI
RGSC_v3.4144,922,562 - 45,025,572 (+)RGD
Celera146,204,164 - 46,271,210 (+)RGD
Sequence:
RefSeq Acc Id: XM_017589896   ⟹   XP_017445385
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,929 - 50,501,568 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039086917   ⟹   XP_038942845
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,929 - 50,496,034 (+)NCBI
RefSeq Acc Id: XM_039086921   ⟹   XP_038942849
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,929 - 50,501,568 (+)NCBI
RefSeq Acc Id: XM_039086925   ⟹   XP_038942853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,794 - 50,498,794 (+)NCBI
RefSeq Acc Id: XM_039086927   ⟹   XP_038942855
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,388,817 - 50,501,568 (+)NCBI
RefSeq Acc Id: XM_039086931   ⟹   XP_038942859
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,388,817 - 50,501,568 (+)NCBI
RefSeq Acc Id: XM_039086935   ⟹   XP_038942863
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,794 - 50,496,034 (+)NCBI
RefSeq Acc Id: XM_039086940   ⟹   XP_038942868
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,794 - 50,496,034 (+)NCBI
RefSeq Acc Id: XM_039086942   ⟹   XP_038942870
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,929 - 50,496,034 (+)NCBI
RefSeq Acc Id: XR_005489952
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2150,387,929 - 50,499,655 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001108493   ⟸   NM_001115021
- UniProtKB: B0BNF5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038942853   ⟸   XM_039086925
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038942863   ⟸   XM_039086935
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038942868   ⟸   XM_039086940
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038942849   ⟸   XM_039086921
- Peptide Label: isoform X3
RefSeq Acc Id: XP_017445385   ⟸   XM_017589896
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_038942870   ⟸   XM_039086942
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038942845   ⟸   XM_039086917
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038942855   ⟸   XM_039086927
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038942859   ⟸   XM_039086931
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000069203   ⟸   ENSRNOT00000089149
RefSeq Acc Id: ENSRNOP00000034413   ⟸   ENSRNOT00000035402
RefSeq Acc Id: ENSRNOP00000023290   ⟸   ENSRNOT00000023290
RefSeq Acc Id: ENSRNOP00000070460   ⟸   ENSRNOT00000086441
RefSeq Acc Id: ENSRNOP00000096216   ⟸   ENSRNOT00000099441
Protein Domains
KH

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1584886 AgrOrtholog
BioCyc Gene G2FUF-61539 BioCyc
Ensembl Genes ENSRNOG00000048297 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000023290 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000034413 UniProtKB/TrEMBL
  ENSRNOP00000069203 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000070460 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000096216 ENTREZGENE
Ensembl Transcript ENSRNOT00000023290 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000035402 UniProtKB/TrEMBL
  ENSRNOT00000086441 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000089149 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000099441 ENTREZGENE
Gene3D-CATH 3.30.1370.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro BBP-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Quaking_NLS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAR_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:499022 UniProtKB/TrEMBL
NCBI Gene 499022 ENTREZGENE
PANTHER PTHR11208 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam KH_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Quaking_NLS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STAR_dimer UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Qki PhenoGen
SMART SM00322 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54791 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUS0_RAT UniProtKB/TrEMBL
  A0A0G2JXZ5_RAT UniProtKB/TrEMBL
  B0BNF5 ENTREZGENE, UniProtKB/TrEMBL
  D4A2X0_RAT UniProtKB/TrEMBL
  F1LMH5_RAT UniProtKB/TrEMBL
  Q91XU1 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-03-22 Qki  QKI, KH domain containing RNA binding  Qk  quaking, KH domain containing RNA binding  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-10-22 Qk  quaking, KH domain containing RNA binding  Qk  quaking  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Qk  quaking  LOC108348175  protein quaking-like  Data Merged 737654 PROVISIONAL
2016-08-02 LOC108348175  protein quaking-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-09-15 Qk  quaking  Qki  quaking homolog, KH domain RNA binding (mouse)  Data Merged 737654 APPROVED
2008-03-05 Qk  quaking  LOC499022  similar to quaking homolog, KH domain RNA binding isoform HQK-6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC499022  similar to quaking homolog, KH domain RNA binding isoform HQK-6      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Qki  quaking homolog, KH domain RNA binding (mouse)    homolog of mouse quaking QKI (KH domain RNA binding protein)  Name updated 1299863 APPROVED
2003-02-27 Qki  homolog of mouse quaking QKI (KH domain RNA binding protein)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains a KH-domain 625530
gene_process mouse homolog may play a role in localization of myelin basic protein (MBP) in oligodendrocytes 625530
gene_process acts as a marker for regenerating myelinating oligodendrocytes 625530
gene_process cytoplasmic protein may facilitate movement of mRNA to myelin via cytoskeleton prior to translation 625530
gene_product member of the RNA binding protein family 625530
gene_regulation elevated levels found in subsets of actively myelinating oligodendrocytes in adult brain and reduced expression observed in mature oligodendrocytes 625530
gene_transcript three isoforms identified 625530