![]()
Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:1604354 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of CDKN2AIP mRNA | CTD | PMID:22079256 | 1,2-dimethylhydrazine | decreases expression | ISO | RGD:1313251 | 6480464 | 1, 2-Dimethylhydrazine results in decreased expression of CDKN2AIP mRNA | CTD | PMID:22206623 | 2-hydroxypropanoic acid | increases expression | ISO | RGD:1604354 | 6480464 | Lactic Acid results in increased expression of CDKN2AIP mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | RGD:1313251 | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in decreased expression of CDKN2AIP mRNA | CTD | PMID:26251327 | 4,4'-diaminodiphenylmethane | affects expression | ISO | RGD:1313251 | 6480464 | 4, 4'-diaminodiphenylmethane affects the expression of CDKN2AIP mRNA | CTD | PMID:18648102 | 5-fluorouracil | affects response to substance | ISO | RGD:1604354 | 6480464 | CDKN2AIP protein affects the susceptibility to Fluorouracil | CTD | PMID:16217747 | acrylamide | increases expression | ISO | RGD:1604354 | 6480464 | Acrylamide results in increased expression of CDKN2AIP mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | ISO | RGD:1313251 | 6480464 | Aflatoxin B1 results in increased expression of CDKN2AIP mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | RGD:1604354 | 6480464 | Aflatoxin B1 results in decreased methylation of CDKN2AIP gene | CTD | PMID:27153756 | aristolochic acid | increases expression | ISO | RGD:1604354 | 6480464 | aristolochic acid I results in increased expression of CDKN2AIP mRNA | CTD | PMID:33212167 | Aroclor 1254 | decreases expression | ISO | RGD:1313251 | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of CDKN2AIP mRNA | CTD | PMID:23650126 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CDKN2AIP mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CDKN2AIP mRNA | CTD | PMID:30816183 | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of CDKN2AIP protein | CTD | PMID:28903499 | cisplatin | affects response to substance | ISO | RGD:1604354 | 6480464 | CDKN2AIP protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | cisplatin | multiple interactions | ISO | RGD:1604354 | 6480464 | Cisplatin promotes the reaction [jinfukang results in decreased expression of CDKN2AIP mRNA], jinfukang promotes the reaction [Cisplatin results in decreased expression of CDKN2AIP mRNA] | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | RGD:1604354 | 6480464 | Cisplatin results in decreased expression of CDKN2AIP mRNA | CTD | PMID:27392435 | cisplatin | increases expression | ISO | RGD:1604354 | 6480464 | Cisplatin results in increased expression of CDKN2AIP mRNA | CTD | PMID:27594783 | copper atom | multiple interactions | ISO | RGD:1604354 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | RGD:1604354 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA | CTD | PMID:24690739 | copper(II) sulfate | increases expression | ISO | RGD:1604354 | 6480464 | Copper Sulfate results in increased expression of CDKN2AIP mRNA | CTD | PMID:19549813 | coumestrol | decreases expression | ISO | RGD:1604354 | 6480464 | Coumestrol results in decreased expression of CDKN2AIP mRNA | CTD | PMID:19167446 | crocidolite asbestos | increases expression | ISO | RGD:1604354 | 6480464 | Asbestos, Crocidolite results in increased expression of CDKN2AIP mRNA | CTD | PMID:18687144 | crocidolite asbestos | decreases expression | ISO | RGD:1313251 | 6480464 | Asbestos, Crocidolite results in decreased expression of CDKN2AIP mRNA | CTD | PMID:29279043 | CU-O LINKAGE | increases expression | ISO | RGD:1604354 | 6480464 | cupric oxide results in increased expression of CDKN2AIP mRNA | CTD | PMID:22077320 | cyclosporin A | increases expression | ISO | RGD:1604354 | 6480464 | Cyclosporine results in increased expression of CDKN2AIP mRNA | CTD | PMID:20106945 | dicrotophos | decreases expression | ISO | RGD:1604354 | 6480464 | dicrotophos results in decreased expression of CDKN2AIP mRNA | CTD | PMID:28302478 | disulfiram | multiple interactions | ISO | RGD:1604354 | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of CDKN2AIP mRNA | CTD | PMID:24690739 | ethyl methanesulfonate | increases expression | ISO | RGD:1604354 | 6480464 | Ethyl Methanesulfonate results in increased expression of CDKN2AIP mRNA | CTD | PMID:23649840 | formaldehyde | increases expression | ISO | RGD:1604354 | 6480464 | Formaldehyde results in increased expression of CDKN2AIP mRNA | CTD | PMID:23649840 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CDKN2AIP mRNA | CTD | PMID:33387578 | gold atom | decreases expression | ISO | RGD:1604354 | 6480464 | Gold results in decreased expression of CDKN2AIP mRNA | CTD | PMID:25523186 | gold(0) | decreases expression | ISO | RGD:1604354 | 6480464 | Gold results in decreased expression of CDKN2AIP mRNA | CTD | PMID:25523186 | ivermectin | decreases expression | ISO | RGD:1604354 | 6480464 | Ivermectin results in decreased expression of CDKN2AIP protein | CTD | PMID:32959892 | leflunomide | increases expression | ISO | RGD:1604354 | 6480464 | leflunomide results in increased expression of CDKN2AIP mRNA | CTD | PMID:28988120 | methyl methanesulfonate | increases expression | ISO | RGD:1604354 | 6480464 | Methyl Methanesulfonate results in increased expression of CDKN2AIP mRNA | CTD | PMID:23649840 | paracetamol | increases expression | ISO | RGD:1604354 | 6480464 | Acetaminophen results in increased expression of CDKN2AIP mRNA | CTD | PMID:21420995 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CDKN2AIP mRNA | CTD | PMID:33387578 | potassium chromate | increases expression | ISO | RGD:1604354 | 6480464 | potassium chromate(VI) results in increased expression of CDKN2AIP mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | RGD:1604354 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of CDKN2AIP mRNA | CTD | PMID:22079256 | progesterone | increases expression | ISO | RGD:1604354 | 6480464 | Progesterone results in increased expression of CDKN2AIP mRNA | CTD | PMID:18070364 | rac-lactic acid | increases expression | ISO | RGD:1604354 | 6480464 | Lactic Acid results in increased expression of CDKN2AIP mRNA | CTD | PMID:30851411 | silver atom | decreases expression | ISO | RGD:1313251 | 6480464 | Silver results in decreased expression of CDKN2AIP mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | RGD:1313251 | 6480464 | Silver results in decreased expression of CDKN2AIP mRNA | CTD | PMID:27131904 | sulforaphane | decreases expression | ISO | RGD:1604354 | 6480464 | sulforaphane results in decreased expression of CDKN2AIP mRNA | CTD | PMID:31838189 | sunitinib | increases expression | ISO | RGD:1604354 | 6480464 | Sunitinib results in increased expression of CDKN2AIP mRNA | CTD | PMID:31533062 | tetrachloromethane | increases expression | ISO | RGD:1313251 | 6480464 | Carbon Tetrachloride results in increased expression of CDKN2AIP mRNA | CTD | PMID:31919559 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CDKN2AIP mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | RGD:1313251 | 6480464 | titanium dioxide results in decreased expression of CDKN2AIP mRNA | CTD | PMID:29264374 | triptonide | increases expression | ISO | RGD:1313251 | 6480464 | triptonide results in increased expression of CDKN2AIP mRNA | CTD | PMID:33045310 | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of CDKN2AIP mRNA | CTD | PMID:24136188 | valproic acid | affects expression | ISO | RGD:1604354 | 6480464 | Valproic Acid affects the expression of CDKN2AIP mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | RGD:1604354 | 6480464 | Valproic Acid results in decreased expression of CDKN2AIP mRNA | CTD | PMID:23179753, PMID:27188386 | withaferin A | decreases expression | ISO | RGD:1604354 | 6480464 | withaferin A results in decreased expression of CDKN2AIP protein | CTD | PMID:22973447 | zoledronic acid | decreases expression | ISO | RGD:1604354 | 6480464 | zoledronic acid results in decreased expression of CDKN2AIP mRNA | CTD | PMID:24714768 | |