Gene: Adk (adenosine kinase) Rattus norvegicus
Analyze
Symbol:
Adk
Name:
adenosine kinase
Description:
Exhibits adenosine kinase activity. Involved in several processes, including adenosine metabolic process; circadian regulation of gene expression; and type B pancreatic cell proliferation. Localizes to the cytoplasm and nucleus. Used to study brain infarction. Biomarker of temporal lobe epilepsy. Human ortholog(s) of this gene implicated in hypermethioninemia due to adenosine kinase deficiency. Orthologous to human ADK (adenosine kinase); PARTICIPATES IN azathioprine pharmacodynamics pathway; mercaptopurine pharmacodynamics pathway; mercaptopurine pharmacokinetics pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 4'-hydroxyacetophenone.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
Adenosin kinase; adenosine 5'-phosphotransferase; AK
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
ADK (adenosine kinase) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):
Adk (adenosine kinase) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Adk (adenosine kinase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
ADK (adenosine kinase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
ADK (adenosine kinase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Adk (adenosine kinase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
ADK (adenosine kinase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
ADK (adenosine kinase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Adk (adenosine kinase) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Mus musculus (house mouse):
Adk (adenosine kinase)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Homo sapiens (human):
ADK (adenosine kinase)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
adka (adenosine kinase a)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Danio rerio (zebrafish):
adkb (adenosine kinase b)
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Saccharomyces cerevisiae (baker's yeast):
ADO1
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
AdenoK
Alliance
DIOPT (Ensembl Compara, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, TreeFam)
Drosophila melanogaster (fruit fly):
Ady43A
Alliance
DIOPT (Ensembl Compara, PANTHER, TreeFam)
Drosophila melanogaster (fruit fly):
CG3809
Alliance
DIOPT (Ensembl Compara, OrthoFinder, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):
R07H5.8
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 15 3,033,535 - 3,435,888 (-) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 3,033,495 - 3,435,888 (-) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 15 3,011,935 - 3,414,198 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 15 3,071,412 - 3,458,891 (-) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 15 3,071,412 - 3,458,891 (-) NCBI Celera 15 1,344,739 - 1,727,570 (+) NCBI Celera Cytogenetic Map 15 p16 NCBI RH 3.4 Map 15 49.2 RGD
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Imported Annotations - ClinVar
hypermethioninemia ISO RGD:737582 8554872 ClinVar Annotator: match by term: Hypermethioninemia ClinVar hypermethioninemia ISO RGD:737582 8554872 ClinVar Annotator: match by term: Hypermethioninemia ClinVar PMID:28492532 hypermethioninemia due to adenosine kinase deficiency ISO RGD:737582 8554872 ClinVar Annotator: match by term: Hypermethioninemia due to adenosine kinase deficiency ClinVar hypermethioninemia due to adenosine kinase deficiency ISO RGD:737582 8554872 ClinVar Annotator: match by term: Hypermethioninemia due to adenosine kinase deficiency ClinVar PMID:21963049 more ... hypermethioninemia due to adenosine kinase deficiency ISO RGD:737582 8554872 ClinVar Annotator: match by OMIM:614300 ClinVar PMID:21963049
Imported Annotations - CTD
hypermethioninemia due to adenosine kinase deficiency ISO RGD:737582 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21963049 Hypoxia ISO RGD:737582 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:19579223 intellectual disability ISO RGD:737582 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21937992 Imported Annotations - MGI
fatty liver disease ISS RGD:10091 13592920 OMIM:228100 MouseDO Imported Annotations - OMIM
hypermethioninemia due to adenosine kinase deficiency ISO RGD:737582 7240710 OMIM
(S)-nicotine increases expression ISO RGD:10091 6480464 Nicotine results in increased expression of ADK mRNA CTD PMID:17997037 17alpha-ethynylestradiol multiple interactions ISO RGD:10091 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADK mRNA CTD PMID:17942748 17beta-estradiol affects expression ISO RGD:737582 6480464 Estradiol affects the expression of ADK mRNA CTD PMID:22574217 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:10091 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of ADK mRNA CTD PMID:17942748 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ADK mRNA CTD PMID:18796159 more ... 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:10091 6480464 Tetrachlorodibenzodioxin affects the expression of ADK mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of ADK mRNA CTD PMID:21346803 2-butoxyethanol increases expression ISO RGD:10091 6480464 n-butoxyethanol results in increased expression of ADK mRNA CTD PMID:19812364 2-hydroxypropanoic acid increases expression ISO RGD:737582 6480464 Lactic Acid results in increased expression of ADK mRNA CTD PMID:30851411 2-methylcholine affects expression ISO RGD:737582 6480464 beta-methylcholine affects the expression of ADK mRNA CTD PMID:21179406 3-phenylprop-2-enal increases expression ISO RGD:737582 6480464 cinnamic aldehyde results in increased expression of ADK mRNA CTD PMID:19524605 4'-hydroxyacetophenone affects binding EXP 6480464 4-hydroxyacetophenone binds to ADK protein CTD PMID:15236443 4,4'-diaminodiphenylmethane affects expression ISO RGD:10091 6480464 4, 4'-diaminodiphenylmethane affects the expression of ADK mRNA CTD PMID:18648102 4-hydroxyphenyl retinamide decreases expression ISO RGD:10091 6480464 Fenretinide results in decreased expression of ADK mRNA CTD PMID:28973697 acetylsalicylic acid affects binding EXP 6480464 Aspirin binds to ADK protein CTD PMID:15236443 aflatoxin B1 affects expression ISO RGD:737582 6480464 Aflatoxin B1 affects the expression of ADK protein CTD PMID:20106945 aflatoxin B1 increases methylation ISO RGD:737582 6480464 Aflatoxin B1 results in increased methylation of ADK intron CTD PMID:30157460 aflatoxin B1 decreases expression ISO RGD:737582 6480464 Aflatoxin B1 results in decreased expression of ADK mRNA CTD PMID:21641981 aflatoxin B1 affects expression ISO RGD:10091 6480464 Aflatoxin B1 affects the expression of ADK mRNA CTD PMID:19770486 aflatoxin B2 increases methylation ISO RGD:737582 6480464 aflatoxin B2 results in increased methylation of ADK intron CTD PMID:30157460 ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of ADK mRNA CTD PMID:16483693 antirheumatic drug increases expression ISO RGD:737582 6480464 Antirheumatic Agents results in increased expression of ADK mRNA CTD PMID:24449571 arsenous acid decreases expression ISO RGD:737582 6480464 Arsenic Trioxide results in decreased expression of ADK protein CTD PMID:25419056 benzo[a]pyrene decreases expression ISO RGD:10091 6480464 Benzo(a)pyrene results in decreased expression of ADK mRNA CTD PMID:19770486 benzo[a]pyrene decreases expression ISO RGD:737582 6480464 Benzo(a)pyrene results in decreased expression of ADK mRNA CTD PMID:20106945 more ... benzo[a]pyrene increases expression ISO RGD:10091 6480464 Benzo(a)pyrene results in increased expression of ADK mRNA CTD PMID:22228805 Benzo[k]fluoranthene decreases expression ISO RGD:10091 6480464 benzo(k)fluoranthene results in decreased expression of ADK mRNA CTD PMID:26377693 bis(2-chloroethyl) sulfide affects expression EXP 6480464 Mustard Gas affects the expression of ADK mRNA CTD PMID:15651846 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of ADK mRNA CTD PMID:25181051 bisphenol A decreases expression ISO RGD:737582 6480464 bisphenol A results in decreased expression of ADK mRNA CTD PMID:29275510 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of ADK promoter CTD PMID:22457795 cadmium sulfate multiple interactions ISO RGD:737582 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ADK mRNA CTD PMID:18654764 carbon nanotube decreases expression ISO RGD:10091 6480464 Nanotubes, Carbon analog results in decreased expression of ADK mRNA CTD PMID:25554681 carbon nanotube increases expression ISO RGD:10091 6480464 Nanotubes, Carbon analog results in increased expression of ADK mRNA, Nanotubes, Carbon results in increased expression of ADK mRNA CTD PMID:25620056 cisplatin decreases expression ISO RGD:737582 6480464 Cisplatin results in decreased expression of ADK mRNA CTD PMID:19561079 clofibrate multiple interactions ISO RGD:10091 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ADK mRNA, PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of ADK mRNA] CTD PMID:17585979 clofibrate decreases expression ISO RGD:10091 6480464 Clofibrate results in decreased expression of ADK mRNA CTD PMID:17585979 clofibric acid multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADK mRNA CTD PMID:17602206 cobalt dichloride multiple interactions ISO RGD:737582 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ADK mRNA CTD PMID:18654764 cobalt dichloride decreases expression ISO RGD:737582 6480464 cobaltous chloride results in decreased expression of ADK mRNA CTD PMID:19376846 copper atom decreases expression EXP 6480464 Copper results in decreased expression of ADK mRNA CTD PMID:22465980 copper(0) decreases expression EXP 6480464 Copper results in decreased expression of ADK mRNA CTD PMID:22465980 copper(II) sulfate decreases expression ISO RGD:737582 6480464 Copper Sulfate results in decreased expression of ADK mRNA CTD PMID:19549813 coumestrol increases expression ISO RGD:737582 6480464 Coumestrol results in increased expression of ADK mRNA CTD PMID:19167446 cyclosporin A decreases expression ISO RGD:10091 6480464 Cyclosporine results in decreased expression of ADK mRNA CTD PMID:19770486 diarsenic trioxide decreases expression ISO RGD:737582 6480464 Arsenic Trioxide results in decreased expression of ADK protein CTD PMID:25419056 dibutyl phthalate decreases expression ISO RGD:10091 6480464 Dibutyl Phthalate results in decreased expression of ADK mRNA CTD PMID:21266533 diclofenac increases expression ISO RGD:737582 6480464 Diclofenac results in increased expression of ADK mRNA CTD PMID:19022234 diclofenac decreases expression EXP 6480464 Diclofenac results in decreased expression of ADK mRNA CTD PMID:19022234 dicrotophos decreases expression ISO RGD:737582 6480464 dicrotophos results in decreased expression of ADK mRNA CTD PMID:28302478 dorsomorphin multiple interactions ISO RGD:737582 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADK mRNA CTD PMID:27188386 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of ADK mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions ISO RGD:737582 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ADK protein CTD PMID:23301498 ethanol affects splicing ISO RGD:10091 6480464 Ethanol affects the splicing of ADK mRNA CTD PMID:30319688 ethyl methanesulfonate decreases expression ISO RGD:737582 6480464 Ethyl Methanesulfonate results in decreased expression of ADK mRNA CTD PMID:23649840 flutamide decreases expression EXP 6480464 Flutamide results in decreased expression of ADK mRNA CTD PMID:24793618 formaldehyde decreases expression ISO RGD:737582 6480464 Formaldehyde results in decreased expression of ADK mRNA CTD PMID:23649840 glafenine decreases expression EXP 6480464 Glafenine results in decreased expression of ADK mRNA CTD PMID:24136188 irinotecan affects expression EXP 6480464 Irinotecan affects the expression of ADK mRNA CTD PMID:20097248 kainic acid increases expression ISO RGD:10091 6480464 Kainic Acid results in increased expression of ADK mRNA CTD PMID:17997037 lead diacetate decreases expression ISO RGD:10091 6480464 lead acetate results in decreased expression of ADK mRNA CTD PMID:20542052 lead(II) chloride multiple interactions ISO RGD:737582 6480464 [cadmium sulfate co-treated with cobaltous chloride co-treated with lead chloride] results in increased expression of ADK mRNA CTD PMID:18654764 lithium atom increases expression EXP 6480464 Lithium results in increased expression of ADK protein CTD PMID:18296634 lithium hydride increases expression EXP 6480464 Lithium results in increased expression of ADK protein CTD PMID:18296634 menadione affects expression ISO RGD:737582 6480464 Vitamin K 3 affects the expression of ADK mRNA CTD PMID:20044591 N-nitrosodiethylamine decreases expression EXP 6480464 Diethylnitrosamine results in decreased expression of ADK mRNA CTD PMID:20360939 N-nitrosodiethylamine multiple interactions EXP 6480464 [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of ADK mRNA CTD PMID:17602206 N-nitrosomorpholine decreases expression EXP 6480464 N-nitrosomorpholine results in decreased expression of ADK protein CTD PMID:19716841 nickel atom multiple interactions ISO RGD:737582 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of ADK mRNA] CTD PMID:14575637 nickel atom affects expression ISO RGD:737582 6480464 Nickel affects the expression of ADK mRNA CTD PMID:14575637 nicotine increases expression ISO RGD:10091 6480464 Nicotine results in increased expression of ADK mRNA CTD PMID:17997037 oxaliplatin multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ADK mRNA CTD PMID:25729387 paracetamol multiple interactions ISO RGD:10091 6480464 [Clofibrate co-treated with Acetaminophen] affects the expression of ADK mRNA more ... CTD PMID:17585979 , PMID:25499718 paracetamol affects expression ISO RGD:10091 6480464 Acetaminophen affects the expression of ADK mRNA CTD PMID:17562736 perfluorododecanoic acid decreases expression EXP 6480464 perfluorododecanoic acid results in decreased expression of ADK protein CTD PMID:26168851 phenobarbital decreases expression ISO RGD:10091 6480464 Phenobarbital results in decreased expression of ADK mRNA CTD PMID:23091169 Propiverine affects binding EXP 6480464 propiverine binds to ADK protein CTD PMID:29273565 protein kinase inhibitor multiple interactions ISO RGD:737582 6480464 Protein Kinase Inhibitors inhibits the reaction [gardiquimod results in decreased expression of ADK mRNA] CTD PMID:28003376 quercitrin decreases expression ISO RGD:737582 6480464 quercitrin results in decreased expression of ADK mRNA CTD PMID:25193878 rac-lactic acid increases expression ISO RGD:737582 6480464 Lactic Acid results in increased expression of ADK mRNA CTD PMID:30851411 Ritodrine decreases expression ISO RGD:10091 6480464 Ritodrine results in decreased expression of ADK mRNA CTD PMID:23370008 SB 431542 multiple interactions ISO RGD:737582 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADK mRNA CTD PMID:27188386 sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of ADK protein CTD PMID:29459688 sodium dichromate affects expression EXP 6480464 sodium bichromate affects the expression of ADK mRNA CTD PMID:22110744 sodium dichromate decreases expression ISO RGD:737582 6480464 sodium bichromate results in decreased expression of ADK mRNA CTD PMID:17685462 sodium fluoride decreases expression ISO RGD:10091 6480464 Sodium Fluoride results in decreased expression of ADK protein CTD PMID:28918527 Soman decreases expression EXP 6480464 Soman results in decreased expression of ADK mRNA CTD PMID:19281266 tauroursodeoxycholic acid decreases expression EXP 6480464 tauroursodeoxycholic acid results in decreased expression of ADK mRNA CTD PMID:15885361 topotecan multiple interactions EXP 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of ADK mRNA CTD PMID:25729387 trichostatin A multiple interactions ISO RGD:737582 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of ADK mRNA] CTD PMID:14575637 trichostatin A increases expression ISO RGD:737582 6480464 trichostatin A results in increased expression of ADK mRNA CTD PMID:24935251 trimellitic anhydride increases expression ISO RGD:10091 6480464 trimellitic anhydride results in increased expression of ADK mRNA CTD PMID:19042947 tungsten increases expression ISO RGD:10091 6480464 Tungsten results in increased expression of ADK mRNA CTD PMID:30912803 valproic acid affects expression ISO RGD:737582 6480464 Valproic Acid affects the expression of ADK mRNA CTD PMID:25979313 valproic acid multiple interactions ISO RGD:737582 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ADK mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:737582 6480464 Valproic Acid results in increased expression of ADK mRNA CTD PMID:23179753 more ... vancomycin increases expression ISO RGD:10091 6480464 Vancomycin results in increased expression of ADK mRNA CTD PMID:18930951 vorinostat increases expression ISO RGD:737582 6480464 Vorinostat results in increased expression of ADK mRNA, Vorinostat results in increased expression of ADK protein CTD PMID:20543569 , PMID:27188386
Biological Process adenosine metabolic process IDA 2291861 RGD AMP biosynthetic process IEA GO:0004001 1600115 GO_REF:0000108 GOC GO_REF:0000108 AMP salvage IEA UniPathway:UPA00588 1600115 GO_REF:0000041 UniProt GO_REF:0000041 circadian regulation of gene expression IEP 2291861 RGD dATP biosynthetic process ISO RGD:10091 1624291 (MGI:MGI:3620422, PMID:12163459) RGD MGI:MGI:3620422 , PMID:12163459 dATP biosynthetic process IEA UniProtKB:P55264 , ensembl:ENSMUSP000000476651600115 GO_REF:0000107 Ensembl GO_REF:0000107 phosphorylation IEA UniProtKB-KW:KW-0418 1600115 GO_REF:0000043 UniProt GO_REF:0000043 positive regulation of cardiac muscle hypertrophy IMP 6482642 RGD positive regulation of T cell proliferation IEP 2313341 decreased expression of mRNA under high glucose in the absence of insulin RGD positive regulation of T cell proliferation IMP 2313341 Adk activity inhibited with 5-iodotubercidin RGD purine ribonucleoside salvage NAS 631740 RGD purine ribonucleoside salvage IEA UniProtKB:P55264 , ensembl:ENSMUSP000000476651600115 GO_REF:0000107 Ensembl GO_REF:0000107 purine ribonucleoside salvage IEA InterPro:IPR001805 1600115 GO_REF:0000002 InterPro GO_REF:0000002 purine ribonucleoside salvage ISO RGD:10091 1624291 (MGI:MGI:3027665, PMID:14736855) RGD MGI:MGI:3027665 , PMID:14736855 type B pancreatic cell proliferation IMP 6482300 RGD Cellular Component cytoplasm IDA 6482302 RGD cytosol IEA UniProtKB:P55263 , ensembl:ENSP000004439651600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytosol IBA MGI:MGI:87930 more ... 13792537 PMID:21873635 GO_Central cytosol ISO RGD:737582 1624291 RGD GO_REF:0000052 cytosol IEA UniProtKB:P55264 , ensembl:ENSMUSP000000476651600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytosol ISO RGD:10091 1624291 (MGI:MGI:55561 more ... RGD MGI:MGI:55561 more ... nucleoplasm ISO RGD:737582 1624291 RGD GO_REF:0000052 nucleoplasm IEA UniProtKB:P55263 , ensembl:ENSP000004439651600115 GO_REF:0000107 Ensembl GO_REF:0000107 nucleus IDA 6482302 RGD nucleus IBA MGI:MGI:87930 more ... 13792537 PMID:21873635 GO_Central nucleus ISO RGD:10091 1624291 (MGI:MGI:3027665, PMID:14736855) RGD MGI:MGI:3027665 , PMID:14736855 Molecular Function adenosine kinase activity IDA 631804 ; 2291861 RGD adenosine kinase activity IBA MGI:MGI:87930 more ... 13792537 PMID:21873635 GO_Central adenosine kinase activity IEA UniProtKB:P55264 , ensembl:ENSMUSP000000476651600115 GO_REF:0000107 Ensembl GO_REF:0000107 adenosine kinase activity IEA InterPro:IPR001805 1600115 GO_REF:0000002 InterPro GO_REF:0000002 adenosine kinase activity ISO RGD:10091 1624291 (MGI:MGI:3027665 more ... RGD MGI:MGI:3027665 more ... ATP binding IEA UniProtKB-KW:KW-0067 1600115 GO_REF:0000043 UniProt GO_REF:0000043 metal ion binding IEA UniProtKB-KW:KW-0479 1600115 GO_REF:0000043 UniProt GO_REF:0000043
Gene-Chemical Interaction Annotations
