Pigfal8 QTL Report (Rattus norvegicus) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
QTL Registration

QTL: Pigfal8 (Plasma insulin-like growth factor 1 level QTL 8) Rattus norvegicus

Symbol: Pigfal8
Name: Plasma insulin-like growth factor 1 level QTL 8
RGD ID: 8552920
Trait: blood insulin-like growth factor amount   (VT:0010479)    
Measurement Type: plasma insulin-like growth factor 1 level   (CMO:0001299)    
LOD Score: 3.0
P Value: Not Available
Variance: 4.5
Position
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2151 - 34,723,002RGD_MAPPER_PIPELINEmRatBN7.2
Rnor_6.0151 - 37,708,474RGD_MAPPER_PIPELINERnor6.0
Rnor_5.0151 - 41,712,083RGD_MAPPER_PIPELINERnor5.0
RGSC_v3.4151 - 36,290,302RGD_MAPPER_PIPELINERGSC3.4
Cross Type: intercross
Strains Crossed: F344/IcoCrlf LOU/NimrOlaHsd 




  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal8Ratdisease of metabolism  IAGP 7794844 RGD 
Pigfal8RatInsulin-Like Growth Factor I Deficiency  IAGP 7794844 RGD 

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal8Ratabnormal circulating insulin-like growth factor I level  IDA 7794844 RGD 

Clinical Measurement
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal8Ratplasma insulin-like growth factor 1 level  IDA 7794844 RGD 

Experimental Condition
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal8Ratcontrolled calorie content diet  IDA 7794844 RGD 
Pigfal8Ratfasting  IDA 7794844 RGD 

Measurement Method
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal8Ratradioimmunoassay  IDA 7794844 RGD 

Rat Strain
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal8RatF344/IcoCrlf  IEA 7794844 RGD 
Pigfal8RatLOU/NimrOlaHsd  IEA 7794844 RGD 

Vertebrate Trait
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Pigfal8Ratblood insulin-like growth factor amount  IDA 7794844 RGD 


#
Reference Title
Reference Citation
1. QTLs influencing IGF-1 levels in a LOU/CxFischer 344F2 rat population. Tracks towards the metabolic theory of Ageing. Marissal-Arvy N, etal., Growth Horm IGF Res. 2013 Dec;23(6):220-8. doi: 10.1016/j.ghir.2013.08.002. Epub 2013 Aug 19.


1 to 20 of 658 rows
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD ID
Symbol
Name
Chr
Start
Stop
Species
1308753Dlg5discs large MAGUK scaffold protein 51575786209735Rat
9173656LOC103693799uncharacterized LOC10369379915269430301400Rat
620715Kcnma1potassium calcium-activated channel subfamily M alpha 1153024801007675Rat
41260545LOC120097301U6 spliceosomal RNA15434956435062Rat
1596707Lrmdaleucine rich melanocyte differentiation associated1512230982284764Rat
40967355LOC120097295U6 spliceosomal RNA1516656381665744Rat
41116341Trnat-agu13transfer RNA threonine (anticodon AGU) 131518559571856028Rat
1312018Zfp503zinc finger protein 5031523130602316848Rat
41024592Trnap-agg44transfer RNA proline (anticodon AGG) 441524273042427384Rat
1306581Comtd1catechol-O-methyltransferase domain containing 11524597832462895Rat
621576Vdac2voltage-dependent anion channel 21524628772476802Rat
1306447Samd8sterile alpha motif domain containing 81525121042562368Rat
163748611Dusp13adual specificity phosphatase 13A1525597632562379Rat
1359712Dusp13bdual specificity phosphatase 13B1525674322575105Rat
11400930LOC108352868uncharacterized LOC1083528681525712732574656Rat
41134379LOC120096899uncharacterized LOC1200968991525842242598079Rat
1310229Dusp29dual specificity phosphatase 291525934732634019Rat
11516251LOC108352871uncharacterized LOC1083528711526081792622047Rat
1566399Kat6blysine acetyltransferase 6B1526388852811977Rat
7665573LOC102553460uncharacterized LOC1025534601528102542817573Rat

1 to 20 of 658 rows
1 to 20 of 681 rows
The following Markers overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Expected Size
Chr
Start
Stop
Species
Match
10877D15Mgh1148152591712825917277Ratregion
34453D15Mgh7132151672552816725660Ratregion
11416D15Wox52151576883547688569Ratregion
33614D15Mit2127151448116514481294Ratregion
33713D15Mit3201151736289717363086Ratregion
33713D15Mit3201151807856318078771Ratregion
36313D15Rat5210151985656619856776Ratregion
35350D15Rat3143152008692420087067Ratregion
35417D15Rat130166152192574621925910Ratregion
37060D15Rat2172151035505410355226Ratregion
37106D15Rat31211152271177322711984Ratregion
37694D15Rat571981577820307782228Ratregion
37702D15Rat66194151918667419186868Ratregion
36516D15Rat12781574119157412193Ratregion
35120D15Rat6182152803066528030847Ratregion
39766D15Rat1291471516040991604246Ratregion
39940D15Rat1092461510582501058496Ratregion
38114D1Rat172267152214124322141514Ratregion
38200D15Rat54223151249614112496364Ratregion
38206D15Rat62195152084273020842925Ratregion
1 to 20 of 681 rows

Peak: (D15Rat110)
Rat AssemblyChrPosition (strand)Source
mRatBN7.21512,222,939 - 12,223,065 (+)MAPPER
Rnor_6.01515,208,412 - 15,208,537NCBI
Rnor_5.01519,212,021 - 19,212,146UniSTS
RGSC_v3.41513,790,222 - 13,790,347UniSTS
RGSC_v3.41513,790,136 - 13,790,469RGD
RGSC_v3.11513,790,222 - 13,790,347RGD
Celera1512,222,535 - 12,222,660UniSTS
RH 3.4 Map1595.5RGD
RH 3.4 Map1595.5UniSTS
RH 2.0 Map1536.8RGD
FHH x ACI Map157.04RGD


1 to 10 of 36 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15105825014481294Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat

1 to 10 of 36 rows


Note Type Note Reference
qtl_general number of animals used: 93 F2 males 7794844
qtl_general software package used: ANOVA; MultiQTL software 7794844
qtl_general measurement method: 4 weeks old rats were fed SAFE-A03 chow; at 18 weeks of age they were fasted overnight, decapitated in the morning and blood samples taken; total Igf-1 level determined by radioimmunoassay 7794844
qtl_general confidence interval from 13.79-71.32 Mb 7794844