Rabggta (Rab geranylgeranyltransferase subunit alpha) - Rat Genome Database

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Gene: Rabggta (Rab geranylgeranyltransferase subunit alpha) Rattus norvegicus
Analyze
Symbol: Rabggta
Name: Rab geranylgeranyltransferase subunit alpha
RGD ID: 621697
Description: Enables Rab geranylgeranyltransferase activity and small GTPase binding activity. Involved in protein geranylgeranylation. Part of Rab-protein geranylgeranyltransferase complex. Orthologous to human RABGGTA (Rab geranylgeranyltransferase subunit alpha); INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: geranylgeranyl transferase type II subunit alpha; geranylgeranyl transferase type-2 subunit alpha; rab geranyl-geranyltransferase subunit alpha; Rab geranylgeranyl transferase, a subunit; Rab geranylgeranyltransferase alpha; Rab geranylgeranyltransferase, alpha subunit; rab GG transferase alpha; rab GGTase alpha
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Rabggta-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21529,206,328 - 29,213,398 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1529,206,157 - 29,213,348 (-)Ensembl
Rnor_6.01534,393,419 - 34,400,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,393,233 - 34,400,449 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,283,389 - 38,290,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,862,275 - 33,868,619 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11533,877,146 - 33,883,992 (-)NCBI
Celera1528,783,370 - 28,789,714 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. cDNA cloning and expression of the alpha and beta subunits of rat Rab geranylgeranyl transferase. Armstrong SA, etal., J Biol Chem 1993 Jun 5;268(16):12221-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Structures of RabGGTase-substrate/product complexes provide insights into the evolution of protein prenylation. Guo Z, etal., EMBO J. 2008 Sep 17;27(18):2444-56. doi: 10.1038/emboj.2008.164. Epub 2008 Aug 28.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase. Pylypenko O, etal., Mol Cell. 2003 Feb;11(2):483-94.
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10737774   PMID:10745007   PMID:12477932   PMID:15489334   PMID:23114750   PMID:28755400   PMID:30053369  


Genomics

Comparative Map Data
Rabggta
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21529,206,328 - 29,213,398 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl1529,206,157 - 29,213,348 (-)Ensembl
Rnor_6.01534,393,419 - 34,400,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,393,233 - 34,400,449 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,283,389 - 38,290,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,862,275 - 33,868,619 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11533,877,146 - 33,883,992 (-)NCBI
Celera1528,783,370 - 28,789,714 (-)NCBICelera
Cytogenetic Map15p13NCBI
RABGGTA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,265,538 - 24,271,627 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1424,265,538 - 24,271,611 (-)EnsemblGRCh38hg38GRCh38
GRCh371424,734,744 - 24,740,833 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,804,584 - 23,810,643 (-)NCBINCBI36hg18NCBI36
Build 341423,804,585 - 23,810,643NCBI
Celera144,599,360 - 4,605,419 (-)NCBI
Cytogenetic Map14q12NCBI
HuRef144,849,901 - 4,855,990 (-)NCBIHuRef
CHM1_11424,733,345 - 24,739,434 (-)NCBICHM1_1
T2T-CHM13v2.01418,463,884 - 18,469,973 (-)NCBI
Rabggta
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,953,321 - 55,959,720 (-)NCBIGRCm39mm39
GRCm39 Ensembl1455,952,873 - 55,959,720 (-)Ensembl
GRCm381455,715,864 - 55,722,263 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,715,416 - 55,722,263 (-)EnsemblGRCm38mm10GRCm38
MGSCv371456,334,714 - 56,341,013 (-)NCBIGRCm37mm9NCBIm37
MGSCv361454,669,948 - 54,676,247 (-)NCBImm8
Celera1453,520,890 - 53,527,189 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
RABGGTA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11423,165,254 - 23,171,339 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,163,034 - 23,171,311 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0145,041,694 - 5,047,775 (-)NCBIMhudiblu_PPA_v0panPan3
RABGGTA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,244,731 - 4,250,836 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,244,781 - 4,250,744 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,166,409 - 4,172,506 (-)NCBI
ROS_Cfam_1.084,355,507 - 4,361,606 (-)NCBI
ROS_Cfam_1.0 Ensembl84,355,513 - 4,361,532 (-)Ensembl
UMICH_Zoey_3.184,045,886 - 4,051,978 (-)NCBI
UNSW_CanFamBas_1.084,107,715 - 4,113,807 (-)NCBI
UU_Cfam_GSD_1.084,370,053 - 4,376,415 (-)NCBI
Rabggta
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864036,099,444 - 36,105,342 (-)NCBI
SpeTri2.0NW_004936722283,682 - 289,548 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RABGGTA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,021,755 - 75,028,875 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,021,716 - 75,028,229 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,292,566 - 80,298,870 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RABGGTA
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,248,637 - 1,254,937 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl241,248,393 - 1,266,254 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603612,933,353 - 12,939,556 (-)NCBIVero_WHO_p1.0
Rabggta
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,230,893 - 8,236,843 (+)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046248208,230,560 - 8,236,843 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
BI278294  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21529,206,773 - 29,206,932 (+)MAPPERmRatBN7.2
Rnor_6.01534,393,865 - 34,394,023NCBIRnor6.0
Rnor_5.01538,283,841 - 38,283,999UniSTSRnor5.0
RGSC_v3.41533,862,062 - 33,862,220UniSTSRGSC3.4
Celera1528,783,157 - 28,783,315UniSTS
RH 3.4 Map15214.1UniSTS
Cytogenetic Map15p13UniSTS
AI071807  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21529,206,412 - 29,206,630 (+)MAPPERmRatBN7.2
Rnor_6.01534,393,504 - 34,393,721NCBIRnor6.0
Rnor_5.01538,283,480 - 38,283,697UniSTSRnor5.0
RGSC_v3.41533,861,701 - 33,861,918UniSTSRGSC3.4
Celera1528,782,796 - 28,783,013UniSTS
RH 3.4 Map15260.81UniSTS
Cytogenetic Map15p13UniSTS
AI410860  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21529,207,004 - 29,207,142 (+)MAPPERmRatBN7.2
Rnor_6.01534,394,096 - 34,394,233NCBIRnor6.0
Rnor_5.01538,284,072 - 38,284,209UniSTSRnor5.0
RGSC_v3.41533,862,293 - 33,862,430UniSTSRGSC3.4
Celera1528,783,388 - 28,783,525UniSTS
RH 3.4 Map15260.61UniSTS
Cytogenetic Map15p13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:49
Count of miRNA genes:49
Interacting mature miRNAs:49
Transcripts:ENSRNOT00000048455
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 47 32 19 32 3 74 34 36 11
Low 8 10 9 9 8 8 1 5 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000048455   ⟹   ENSRNOP00000049261
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1529,206,157 - 29,213,348 (-)Ensembl
Rnor_6.0 Ensembl1534,393,233 - 34,400,449 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099074   ⟹   ENSRNOP00000077243
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1529,206,324 - 29,213,302 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108610   ⟹   ENSRNOP00000091502
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1529,206,157 - 29,213,284 (-)Ensembl
RefSeq Acc Id: NM_031654   ⟹   NP_113842
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21529,206,987 - 29,213,331 (-)NCBI
Rnor_6.01534,394,078 - 34,400,422 (-)NCBI
Rnor_5.01538,283,389 - 38,290,429 (-)NCBI
RGSC_v3.41533,862,275 - 33,868,619 (-)RGD
Celera1528,783,370 - 28,789,714 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252009   ⟹   XP_006252071
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21529,206,328 - 29,213,302 (-)NCBI
Rnor_6.01534,393,419 - 34,400,381 (-)NCBI
Rnor_5.01538,283,389 - 38,290,429 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252010   ⟹   XP_006252072
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21529,206,328 - 29,213,398 (-)NCBI
Rnor_6.01534,393,419 - 34,400,466 (-)NCBI
Rnor_5.01538,283,389 - 38,290,429 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_113842   ⟸   NM_031654
- UniProtKB: Q08602 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006252072   ⟸   XM_006252010
- Peptide Label: isoform X1
- UniProtKB: Q08602 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006252071   ⟸   XM_006252009
- Peptide Label: isoform X1
- UniProtKB: Q08602 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000049261   ⟸   ENSRNOT00000048455
RefSeq Acc Id: ENSRNOP00000077243   ⟸   ENSRNOT00000099074
RefSeq Acc Id: ENSRNOP00000091502   ⟸   ENSRNOT00000108610

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q08602-F1-model_v2 AlphaFold Q08602 1-567 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699686
Promoter ID:EPDNEW_R10209
Type:initiation region
Name:Rabggta_1
Description:Rab geranylgeranyltransferase, alpha subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01534,400,443 - 34,400,503EPDNEW

Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621697 AgrOrtholog
BioCyc Gene G2FUF-13695 BioCyc
Ensembl Genes ENSRNOG00000030483 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000049261 ENTREZGENE
  ENSRNOP00000077243.1 UniProtKB/TrEMBL
  ENSRNOP00000091502 ENTREZGENE
  ENSRNOP00000091502.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000048455 ENTREZGENE
  ENSRNOT00000099074.1 UniProtKB/TrEMBL
  ENSRNOT00000108610 ENTREZGENE
  ENSRNOT00000108610.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7301723 IMAGE-MGC_LOAD
InterPro LRR_dom_sf UniProtKB/Swiss-Prot
  Prenyl_trans_a UniProtKB/Swiss-Prot
  RabGGT_asu_insert-dom_sf UniProtKB/Swiss-Prot
  RabGGT_asu_insert-domain UniProtKB/Swiss-Prot
  RabGGTase_alpha UniProtKB/Swiss-Prot
KEGG Report rno:58983 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105396 IMAGE-MGC_LOAD
NCBI Gene 58983 ENTREZGENE
PANTHER PTHR11129:SF2 UniProtKB/Swiss-Prot
Pfam PPTA UniProtKB/Swiss-Prot
  RabGGT_insert UniProtKB/Swiss-Prot
PhenoGen Rabggta PhenoGen
PROSITE PFTA UniProtKB/Swiss-Prot
Superfamily-SCOP SSF49594 UniProtKB/Swiss-Prot
UniProt A0A8I5ZK93_RAT UniProtKB/TrEMBL
  A0A8I6GJ12_RAT UniProtKB/TrEMBL
  PGTA_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-04 Rabggta  Rab geranylgeranyltransferase subunit alpha  Rabggta  Rab geranylgeranyltransferase, alpha subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-24 Rabggta  Rab geranylgeranyltransferase, alpha subunit  Rabggta  Rab geranylgeranyl transferase, a subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Rabggta  Rab geranylgeranyl transferase, a subunit      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Rabggta  Rab geranylgeranyl transferase, a subunit      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_physical_interaction combines with beta subunit Rabggtb to form Component B of the Rab geranylgeranyl transferase, which combines with an additional Component A for enzyme activity 69952