Dad1 (defender against cell death 1) - Rat Genome Database

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Gene: Dad1 (defender against cell death 1) Rattus norvegicus
Analyze
Symbol: Dad1
Name: defender against cell death 1
RGD ID: 621028
Description: Predicted to enable enzyme activator activity. Involved in response to nutrient and response to xenobiotic stimulus. Predicted to be part of oligosaccharyltransferase complex A and oligosaccharyltransferase complex B. Orthologous to human DAD1 (defender against cell death 1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; N-linked glycan biosynthetic pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DAD-1; dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1; oligosaccharyl transferase subunit DAD1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,647,326 - 31,667,159 (-)NCBIGRCr8
mRatBN7.21527,677,286 - 27,697,120 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,677,268 - 27,697,347 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,518,815 - 29,538,699 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,665,754 - 30,685,523 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01528,915,796 - 28,935,565 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01532,868,136 - 32,887,933 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1532,868,087 - 32,888,095 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01536,679,088 - 36,699,062 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,285,592 - 32,305,885 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,301,291 - 32,321,585 (-)NCBI
Celera1527,259,040 - 27,278,828 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-bromohexadecanoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
arsenous acid  (ISO)
azoxystrobin  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
cadmium acetate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (ISO)
doxorubicin  (ISO)
elemental selenium  (EXP)
ethanol  (EXP)
folic acid  (ISO)
genistein  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
indometacin  (ISO)
ivermectin  (ISO)
Mesaconitine  (EXP)
methamphetamine  (EXP)
methidathion  (ISO)
methimazole  (EXP)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
N-nitrosodiethylamine  (EXP)
nickel dichloride  (EXP)
nitrates  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (EXP,ISO)
phenobarbital  (EXP)
picoxystrobin  (ISO)
poly(vinylpyrrolidone)  (EXP)
procymidone  (EXP)
Propiverine  (EXP)
pyrimidifen  (ISO)
rac-lactic acid  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
SCH 23390  (EXP)
selenium atom  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
triadimefon  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Effect of selenium and vitamin E deficiency on differential gene expression in rat liver. Fischer A, etal., Biochem Biophys Res Commun. 2001 Jul 13;285(2):470-5.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. GOA pipeline RGD automated data pipeline
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Gene expression analysis in the ventral prostate of rats exposed to vinclozolin or procymidone. Rosen MB, etal., Reprod Toxicol. 2005 Jan-Feb;19(3):367-79.
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10748466   PMID:12887896   PMID:15489334   PMID:19946888   PMID:22467853   PMID:23376485  


Genomics

Comparative Map Data
Dad1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81531,647,326 - 31,667,159 (-)NCBIGRCr8
mRatBN7.21527,677,286 - 27,697,120 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1527,677,268 - 27,697,347 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1529,518,815 - 29,538,699 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01530,665,754 - 30,685,523 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01528,915,796 - 28,935,565 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01532,868,136 - 32,887,933 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1532,868,087 - 32,888,095 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01536,679,088 - 36,699,062 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,285,592 - 32,305,885 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11532,301,291 - 32,321,585 (-)NCBI
Celera1527,259,040 - 27,278,828 (-)NCBICelera
Cytogenetic Map15p13NCBI
DAD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381422,564,907 - 22,589,224 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1422,564,907 - 22,589,224 (-)EnsemblGRCh38hg38GRCh38
GRCh371423,033,807 - 23,058,130 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361422,103,647 - 22,127,969 (-)NCBINCBI36Build 36hg18NCBI36
Build 341422,103,646 - 22,127,969NCBI
Celera142,896,859 - 2,921,191 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef143,152,065 - 3,176,551 (-)NCBIHuRef
CHM1_11423,032,809 - 23,057,139 (-)NCBICHM1_1
T2T-CHM13v2.01416,762,628 - 16,786,951 (-)NCBIT2T-CHM13v2.0
Dad1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391454,472,942 - 54,491,386 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1454,472,936 - 54,491,561 (-)EnsemblGRCm39 Ensembl
GRCm381454,235,485 - 54,253,929 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1454,235,479 - 54,254,104 (-)EnsemblGRCm38mm10GRCm38
MGSCv371454,855,160 - 54,873,604 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361453,193,491 - 53,211,877 (-)NCBIMGSCv36mm8
Celera1452,031,369 - 52,050,171 (-)NCBICelera
Cytogenetic Map14C2NCBI
cM Map1427.7NCBI
Dad1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540937,670,274 - 37,688,391 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540937,670,266 - 37,688,226 (+)NCBIChiLan1.0ChiLan1.0
DAD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21524,013,115 - 24,044,990 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11423,229,601 - 23,254,008 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0143,401,048 - 3,425,359 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11421,502,618 - 21,526,793 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1421,502,618 - 21,526,793 (-)Ensemblpanpan1.1panPan2
DAD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.182,963,719 - 2,984,978 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha82,913,614 - 2,934,653 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.083,071,124 - 3,092,393 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl83,070,735 - 3,092,373 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.182,763,845 - 2,785,098 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.082,825,279 - 2,846,498 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.083,087,258 - 3,108,519 (-)NCBIUU_Cfam_GSD_1.0
Dad1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864034,690,409 - 34,710,031 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367221,678,862 - 1,698,579 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367221,678,952 - 1,698,583 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DAD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl776,432,051 - 76,457,192 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1776,432,040 - 76,457,403 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2781,668,608 - 81,693,971 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DAD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12922,935,231 - 22,958,331 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2922,935,005 - 22,958,414 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605923,465,308 - 23,488,458 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dad1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248259,045,163 - 9,082,634 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248259,062,984 - 9,081,939 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dad1
89 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:50
Count of miRNA genes:40
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000012233
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat

Markers in Region
AW557067  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21527,685,287 - 27,685,437 (+)MAPPERmRatBN7.2
Rnor_6.01532,876,138 - 32,876,287NCBIRnor6.0
Rnor_5.01536,687,267 - 36,687,416UniSTSRnor5.0
RGSC_v3.41532,294,087 - 32,294,236UniSTSRGSC3.4
Celera1527,267,033 - 27,267,182UniSTS
Cytogenetic Map15p13UniSTS
RH133381  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2224,859,980 - 24,860,177 (+)MAPPERmRatBN7.2
mRatBN7.21527,691,609 - 27,691,806 (+)MAPPERmRatBN7.2
Rnor_6.01532,882,459 - 32,882,655NCBIRnor6.0
Rnor_6.0223,236,683 - 23,236,879NCBIRnor6.0
Rnor_5.01536,693,588 - 36,693,784UniSTSRnor5.0
Rnor_5.0242,418,108 - 42,418,304UniSTSRnor5.0
RGSC_v3.4223,923,761 - 23,923,957UniSTSRGSC3.4
RGSC_v3.41532,300,411 - 32,300,607UniSTSRGSC3.4
Celera1527,273,354 - 27,273,550UniSTS
Celera220,935,169 - 20,935,365UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map15p13UniSTS
UniSTS:99121  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21527,696,876 - 27,696,986 (+)MAPPERmRatBN7.2
Rnor_6.01532,887,726 - 32,887,835NCBIRnor6.0
Rnor_5.01536,698,855 - 36,698,964UniSTSRnor5.0
RGSC_v3.41532,305,678 - 32,305,787UniSTSRGSC3.4
Celera1527,278,621 - 27,278,730UniSTS
Cytogenetic Map15p13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000012233   ⟹   ENSRNOP00000012233
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1527,677,268 - 27,697,347 (-)Ensembl
Rnor_6.0 Ensembl1532,868,087 - 32,888,095 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000098684   ⟹   ENSRNOP00000092852
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1527,677,289 - 27,697,136 (-)Ensembl
RefSeq Acc Id: NM_001393807   ⟹   NP_001380736
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,647,326 - 31,667,159 (-)NCBI
mRatBN7.21527,677,286 - 27,697,120 (-)NCBI
RefSeq Acc Id: NM_138910   ⟹   NP_620265
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81531,647,326 - 31,667,159 (-)NCBI
mRatBN7.21527,677,286 - 27,697,120 (-)NCBI
Rnor_6.01532,868,136 - 32,887,933 (-)NCBI
Rnor_5.01536,679,088 - 36,699,062 (-)NCBI
RGSC_v3.41532,285,592 - 32,305,885 (-)RGD
Celera1527,259,040 - 27,278,828 (-)RGD
Sequence:
RefSeq Acc Id: NP_620265   ⟸   NM_138910
- Peptide Label: isoform 2
- UniProtKB: P61805 (UniProtKB/Swiss-Prot),   A6KGR8 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000012233   ⟸   ENSRNOT00000012233
Ensembl Acc Id: ENSRNOP00000092852   ⟸   ENSRNOT00000098684
RefSeq Acc Id: NP_001380736   ⟸   NM_001393807
- Peptide Label: isoform 1
- UniProtKB: A0A8L2Q6I7 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61805-F1-model_v2 AlphaFold P61805 1-113 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699646
Promoter ID:EPDNEW_R10169
Type:initiation region
Name:Dad1_1
Description:defender against cell death 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01532,887,933 - 32,887,993EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621028 AgrOrtholog
BioCyc Gene G2FUF-13816 BioCyc
BioCyc Pathway MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS [protein N-glycosylation initial phase (eukaryotic)] BioCyc
BioCyc Pathway Image MANNOSYL-CHITO-DOLICHOL-BIOSYNTHESIS BioCyc
Ensembl Genes ENSRNOG00000009090 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012233 ENTREZGENE
  ENSRNOT00000012233.6 UniProtKB/TrEMBL
  ENSRNOT00000098684 ENTREZGENE
  ENSRNOT00000098684.1 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6917861 IMAGE-MGC_LOAD
InterPro DAD/Ost2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:192275 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72685 IMAGE-MGC_LOAD
NCBI Gene 192275 ENTREZGENE
PANTHER DOLICHYL-DIPHOSPHOOLIGOSACCHARIDE--PROTEIN GLYCOSYLTRANSFERASE SUBUNIT DAD1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10705 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dad1 PhenoGen
PIRSF DAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009090 RatGTEx
UniProt A0A8L2Q6I7 ENTREZGENE, UniProtKB/TrEMBL
  A6KGR8 ENTREZGENE, UniProtKB/TrEMBL
  A6KGR9_RAT UniProtKB/TrEMBL
  DAD1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary O08552 UniProtKB/Swiss-Prot
  O70364 UniProtKB/Swiss-Prot
  P46966 UniProtKB/Swiss-Prot
  P46968 UniProtKB/Swiss-Prot
  Q96GB7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Dad1  defender against cell death 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Dad1  defender against cell death 1      Symbol and Name status set to provisional 70820 PROVISIONAL