Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAD1 mRNA | CTD | PMID:22206623 | 17beta-estradiol | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Estradiol results in increased expression of DAD1 mRNA | CTD | PMID:16474171 | 17beta-estradiol | increases expression | EXP | | 6480464 | Estradiol results in increased expression of DAD1 mRNA | CTD | PMID:32145629 | 17beta-estradiol | affects expression | ISO | Dad1 (Mus musculus) | 6480464 | Estradiol affects the expression of DAD1 mRNA | CTD | PMID:15598610 | 2,2',4,4'-Tetrabromodiphenyl ether | affects expression | ISO | Dad1 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:30294300 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DAD1 mRNA | CTD | PMID:19520675 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DAD1 mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dad1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DAD1 mRNA | CTD | PMID:21570461 and PMID:24680724 | 2-hydroxypropanoic acid | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DAD1 mRNA | CTD | PMID:30851411 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | DAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DAD1 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Dad1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of DAD1 mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [bisphenol S co-treated with Tretinoin] results in decreased expression of DAD1 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of DAD1 protein | CTD | PMID:34186270 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of DAD1 mRNA | CTD | PMID:30047161 | acrylamide | affects expression | EXP | | 6480464 | Acrylamide affects the expression of DAD1 mRNA | CTD | PMID:28959563 | aflatoxin B1 | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of DAD1 mRNA | CTD | PMID:27153756 | aflatoxin B1 | increases methylation | ISO | DAD1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of DAD1 gene | CTD | PMID:27153756 | all-trans-retinoic acid | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in decreased expression of DAD1 mRNA more ... | CTD | PMID:30951980 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of DAD1 mRNA | CTD | PMID:30047161 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of DAD1 mRNA | CTD | PMID:16483693 | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of DAD1 mRNA | CTD | PMID:30779732 | arsenous acid | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of DAD1 protein | CTD | PMID:25419056 | azoxystrobin | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | azoxystrobin results in increased expression of DAD1 mRNA | CTD | PMID:33512557 | bisphenol A | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of DAD1 mRNA | CTD | PMID:16474171 | bisphenol A | decreases expression | ISO | Dad1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of DAD1 mRNA | CTD | PMID:33221593 | bisphenol A | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [bisphenol A co-treated with Tretinoin] results in decreased expression of DAD1 mRNA | CTD | PMID:30951980 | bisphenol A | affects expression | ISO | DAD1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of DAD1 mRNA | CTD | PMID:30903817 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DAD1 mRNA | CTD | PMID:25181051 and PMID:32145629 | Bisphenol B | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of DAD1 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | DAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DAD1 mRNA | CTD | PMID:28628672 | bisphenol F | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | bisphenol F results in increased expression of DAD1 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [bisphenol F co-treated with Tretinoin] results in decreased expression of DAD1 mRNA | CTD | PMID:30951980 | caffeine | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Caffeine results in decreased expression of DAD1 mRNA | CTD | PMID:11793227 | chloropicrin | affects expression | ISO | DAD1 (Homo sapiens) | 6480464 | chloropicrin affects the expression of DAD1 mRNA | CTD | PMID:26352163 | chlorpyrifos | increases expression | ISO | Dad1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of DAD1 mRNA | CTD | PMID:37019170 | cisplatin | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of DAD1 mRNA and Cisplatin results in increased expression of DAD1 protein | CTD | PMID:21278888 | clobetasol | increases expression | ISO | Dad1 (Mus musculus) | 6480464 | Clobetasol results in increased expression of DAD1 mRNA | CTD | PMID:27462272 | clofibrate | decreases expression | ISO | Dad1 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of DAD1 mRNA | CTD | PMID:17585979 | cobalt dichloride | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of DAD1 mRNA | CTD | PMID:19376846 | copper(II) sulfate | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of DAD1 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DAD1 mRNA | CTD | PMID:20106945 | dexamethasone | multiple interactions | ISO | DAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DAD1 mRNA | CTD | PMID:28628672 | diarsenic trioxide | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of DAD1 protein | CTD | PMID:25419056 | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of DAD1 mRNA | CTD | PMID:22546817 | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of DAD1 mRNA | CTD | PMID:22546817 | diethylstilbestrol | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Diethylstilbestrol results in increased expression of DAD1 mRNA | CTD | PMID:15766595 | diethylstilbestrol | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of DAD1 mRNA | CTD | PMID:36621641 | doxorubicin | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of DAD1 mRNA | CTD | PMID:29803840 | elemental selenium | multiple interactions | EXP | | 6480464 | [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of DAD1 mRNA | CTD | PMID:11444866 | ethanol | increases expression | EXP | | 6480464 | Ethanol results in increased expression of DAD1 mRNA | CTD | PMID:15353170 | folic acid | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of DAD1 mRNA | CTD | PMID:22206623 | genistein | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Genistein results in increased expression of DAD1 mRNA | CTD | PMID:16474171 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of DAD1 mRNA | CTD | PMID:33387578 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of DAD1 mRNA | CTD | PMID:24136188 | indometacin | multiple interactions | ISO | DAD1 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of DAD1 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DAD1 protein | CTD | PMID:32959892 | Mesaconitine | increases expression | EXP | | 6480464 | mesaconitine results in increased expression of DAD1 protein | CTD | PMID:37182599 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of DAD1 mRNA | CTD | PMID:19564919 | methamphetamine | multiple interactions | EXP | | 6480464 | SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA] | CTD | PMID:19564919 | methidathion | increases expression | ISO | Dad1 (Mus musculus) | 6480464 | methidathion results in increased expression of DAD1 mRNA | CTD | PMID:34813904 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of DAD1 mRNA | CTD | PMID:30047161 | N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | N more ... | CTD | PMID:12888634 | N-nitrosodiethylamine | decreases expression | EXP | | 6480464 | Diethylnitrosamine results in decreased expression of DAD1 mRNA | CTD | PMID:11323195 | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of DAD1 mRNA | CTD | PMID:22546817 | p-menthan-3-ol | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Menthol results in decreased expression of DAD1 mRNA | CTD | PMID:26760959 | paracetamol | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of DAD1 mRNA | CTD | PMID:11793227 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of DAD1 mRNA | CTD | PMID:33387578 | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of DAD1 mRNA | CTD | PMID:16510358 more ... | picoxystrobin | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | picoxystrobin results in increased expression of DAD1 mRNA | CTD | PMID:33512557 | poly(vinylpyrrolidone) | multiple interactions | EXP | | 6480464 | [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA | CTD | PMID:25194297 | procymidone | decreases expression | EXP | | 6480464 | procymidone results in decreased expression of DAD1 mRNA | CTD | PMID:15686871 | Propiverine | affects binding | EXP | | 6480464 | propiverine binds to DAD1 protein | CTD | PMID:29273565 | pyrimidifen | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | pyrimidifen results in increased expression of DAD1 mRNA | CTD | PMID:33512557 | rac-lactic acid | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of DAD1 mRNA | CTD | PMID:30851411 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of DAD1 mRNA | CTD | PMID:28374803 | rotenone | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Rotenone results in increased expression of DAD1 mRNA | CTD | PMID:33512557 | SB 431542 | multiple interactions | ISO | DAD1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in decreased expression of DAD1 protein | CTD | PMID:37664457 | SCH 23390 | multiple interactions | EXP | | 6480464 | SCH 23390 inhibits the reaction [Methamphetamine results in increased expression of DAD1 mRNA] | CTD | PMID:19564919 | selenium atom | multiple interactions | EXP | | 6480464 | [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of DAD1 mRNA | CTD | PMID:11444866 | silver atom | multiple interactions | EXP | | 6480464 | [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA | CTD | PMID:25194297 | silver(0) | multiple interactions | EXP | | 6480464 | [Silver analog co-treated with Povidone] results in decreased expression of DAD1 mRNA | CTD | PMID:25194297 | sodium arsenite | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of DAD1 mRNA | CTD | PMID:12760830 | sodium fluoride | decreases expression | ISO | Dad1 (Mus musculus) | 6480464 | Sodium Fluoride results in decreased expression of DAD1 protein | CTD | PMID:28918527 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of DAD1 mRNA | CTD | PMID:30047161 | testosterone | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of DAD1 mRNA | CTD | PMID:33359661 | tetrachloroethene | decreases expression | ISO | Dad1 (Mus musculus) | 6480464 | Tetrachloroethylene results in decreased expression of DAD1 mRNA | CTD | PMID:28973375 | tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of DAD1 mRNA | CTD | PMID:15963342 | tetrachloromethane | increases expression | ISO | Dad1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of DAD1 mRNA | CTD | PMID:31919559 | thioacetamide | decreases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Thioacetamide results in decreased expression of DAD1 mRNA | CTD | PMID:11793227 | triadimefon | increases expression | EXP | | 6480464 | triadimefon results in increased expression of DAD1 mRNA | CTD | PMID:30047161 | trichloroethene | increases expression | ISO | Dad1 (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of DAD1 mRNA | CTD | PMID:15363585 | trichloroethene | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | PPARA protein inhibits the reaction [Trichloroethylene results in increased expression of DAD1 protein] | CTD | PMID:15363585 | valproic acid | affects expression | ISO | DAD1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DAD1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | DAD1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of DAD1 mRNA | CTD | PMID:28001369 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of DAD1 mRNA | CTD | PMID:15686871 | vitamin E | multiple interactions | EXP | | 6480464 | [Selenium deficiency co-treated with Vitamin E deficiency] results in decreased expression of DAD1 mRNA | CTD | PMID:11444866 | zinc atom | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [Zinc deficiency promotes the reaction [TRP53 gene mutant form results in increased susceptibility to nitrosobenzylmethylamine]] which results in increased expression of DAD1 mRNA | CTD | PMID:12517797 | zinc(0) | multiple interactions | ISO | Dad1 (Mus musculus) | 6480464 | [Zinc deficiency promotes the reaction [TRP53 gene mutant form results in increased susceptibility to nitrosobenzylmethylamine]] which results in increased expression of DAD1 mRNA | CTD | PMID:12517797 | |