Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Prmt5 (protein arginine methyltransferase 5) Rattus norvegicus
Symbol: Prmt5
Name: protein arginine methyltransferase 5
Description: Predicted to have several functions, including p53 binding activity; protein-arginine N-methyltransferase activity; and sequence-specific DNA binding activity. Involved in several processes, including liver regeneration; positive regulation of oligodendrocyte differentiation; and regulation of ERK1 and ERK2 cascade. Localizes to protein-containing complex. Biomarker of asthma. Orthologous to human PRMT5 (protein arginine methyltransferase 5); PARTICIPATES IN histone modification pathway; homocysteine metabolic pathway; methionine cycle/metabolic pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: HMT1 hnRNP methyltransferase-like 5; Hrmt1l5; LOC364382; protein arginine N-methyltransferase 5; Skb1; SKB1 homolog; SKB1 homolog (S. pombe)
Homo sapiens (human) : PRMT5 (protein arginine methyltransferase 5)  HGNC  Alliance
Mus musculus (house mouse) : Prmt5 (protein arginine N-methyltransferase 5)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prmt5 (protein arginine methyltransferase 5)
Pan paniscus (bonobo/pygmy chimpanzee) : PRMT5 (protein arginine methyltransferase 5)
Canis lupus familiaris (dog) : PRMT5 (protein arginine methyltransferase 5)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prmt5 (protein arginine methyltransferase 5)
Sus scrofa (pig) : PRMT5 (protein arginine methyltransferase 5)
Chlorocebus sabaeus (African green monkey) : PRMT5 (protein arginine methyltransferase 5)
Heterocephalus glaber (naked mole-rat) : Prmt5 (protein arginine methyltransferase 5)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01533,156,508 - 33,165,893 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1533,156,492 - 33,165,895 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01537,041,740 - 37,051,125 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41532,574,951 - 32,584,336 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11532,590,652 - 32,600,343 (-)NCBI
Celera1527,551,512 - 27,560,897 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Prmt5
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309053
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.