Spetex2e (Spetex-2E protein) - Rat Genome Database

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Gene: Spetex2e (Spetex-2E protein) Rattus norvegicus
Analyze
Symbol: Spetex2e (Ensembl: Spetex-2E)
Name: Spetex-2E protein
RGD ID: 1359714
Description: INTERACTS WITH indole-3-methanol; Monobutylphthalate; ochratoxin A
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100360667; LOC108352882; LOC498444; similar to Spetex-2E protein; Spetex-2E; Spetex-2G protein-like; uncharacterized LOC108352882; uncharacterized protein LOC108352882
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8157,244,519 - 7,247,668 (+)NCBIGRCr8
mRatBN7.2154,813,644 - 4,816,793 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl154,739,331 - 4,816,815 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx156,946,340 - 6,949,489 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0157,859,052 - 7,862,201 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0156,159,539 - 6,162,688 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0983,416,906 - 83,420,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0159,451,365 - 9,501,593 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4156,289,492 - 6,292,666 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1156,289,491 - 6,292,664 (+)NCBI
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Molecular cloning of rat Spetex2 family genes mapped on chromosome 15p16, encoding a 23-kilodalton protein associated with the plasma membranes of haploid spermatids. Iwamoto Y, etal., Biol Reprod 2005 Feb;72(2):284-92. Epub 2004 Sep 15.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Spetex2e
174 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15105825014481294Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)colorectal tumor number (CMO:0001794)15226636822711984Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat

Markers in Region
AW531802  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.281,921,117 - 1,921,268 (+)MAPPERmRatBN7.2
mRatBN7.2154,615,370 - 4,615,517 (-)MAPPERmRatBN7.2
Rnor_6.081,933,354 - 1,933,504NCBIRnor6.0
Rnor_5.081,956,740 - 1,956,890UniSTSRnor5.0
Celera81,800,389 - 1,800,539UniSTS
Celera15250 - 399UniSTS
RH 3.4 Map1568.9UniSTS
Cytogenetic Map15p16UniSTS
Cytogenetic Map8q11UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000061525   ⟹   ENSRNOP00000058243
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl154,739,331 - 4,816,815 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000080252   ⟹   ENSRNOP00000073067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl154,793,512 - 4,816,815 (+)Ensembl
RefSeq Acc Id: NM_001011702   ⟹   NP_001011702
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8157,244,519 - 7,247,668 (+)NCBI
mRatBN7.2154,813,644 - 4,816,793 (+)NCBI
Rnor_6.0983,417,024 - 83,420,181 (-)NCBI
Rnor_5.0159,451,365 - 9,501,593 (-)NCBI
RGSC_v3.4156,289,492 - 6,292,666 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001011702 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein BAD83787 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000058243.4
  ENSRNOP00000073067
  ENSRNOP00000073067.2
Reference Protein Sequences
RefSeq Acc Id: NP_001011702   ⟸   NM_001011702
- UniProtKB: Q5KT05 (UniProtKB/TrEMBL),   A0A0G2K4J5 (UniProtKB/TrEMBL),   F1LXX8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073067   ⟸   ENSRNOT00000080252
RefSeq Acc Id: ENSRNOP00000058243   ⟸   ENSRNOT00000061525
Protein Domains
Disks large homolog 5 N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K4J5-F1-model_v2 AlphaFold A0A0G2K4J5 1-196 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-14492 BioCyc
Ensembl Genes ENSRNOG00000065267 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000061525.5 UniProtKB/TrEMBL
  ENSRNOT00000080252 ENTREZGENE
  ENSRNOT00000080252.2 UniProtKB/TrEMBL
InterPro DUF622 UniProtKB/TrEMBL
KEGG Report rno:361012 UniProtKB/TrEMBL
NCBI Gene 361012 ENTREZGENE
PANTHER 2610042L04RIK PROTEIN-RELATED UniProtKB/TrEMBL
  SPEER/SPETEX UniProtKB/TrEMBL
Pfam DUF622 UniProtKB/TrEMBL
PhenoGen Spetex2e PhenoGen
RatGTEx ENSRNOG00000065267 RatGTEx
UniProt A0A0G2K4J5 ENTREZGENE
  F1LXX8 ENTREZGENE, UniProtKB/TrEMBL
  Q5KT05 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A0A0G2K4J5 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-05-05 Spetex2e  Spetex-2E protein  Spetex-2E  Spetex-2E protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2021-03-09 Spetex-2E  Spetex-2E protein  LOC108352882  uncharacterized LOC108352882  Data merged from RGD:11435680 737654 PROVISIONAL
2016-08-02 LOC108352882  uncharacterized LOC108352882      Symbol and Name status set to provisional 70820 PROVISIONAL
2015-07-29 Spetex-2E  Spetex-2E protein  LOC100360667  Spetex-2G protein-like  Data merged from RGD:2321690 737654 PROVISIONAL
2015-07-29 Spetex-2E  Spetex-2E protein  LOC498444  similar to Spetex-2E protein  Data merged from RGD:1591968 737654 PROVISIONAL
2010-05-06 LOC100360667  Spetex-2G protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC498444  similar to Spetex-2E protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-07-29 Spetex-2E  Spetex-2E protein      Symbol and Name status set to provisional 70820 PROVISIONAL