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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lrp10 | Rat | (-)-demecolcine | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of LRP10 mRNA | CTD | PMID:23649840 | Lrp10 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Lrp10 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of LRP10 mRNA] | CTD | PMID:22206623 | Lrp10 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Lrp10 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of LRP10 mRNA | CTD | PMID:22206623 | Lrp10 | Rat | 17beta-estradiol | increases expression | ISO | Lrp10 (Mus musculus) | 6480464 | Estradiol results in increased expression of LRP10 mRNA | CTD | PMID:39298647 | Lrp10 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LRP10 mRNA | CTD | PMID:20106945 and PMID:21632981 | Lrp10 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of LRP10 mRNA | CTD | PMID:34747641 | Lrp10 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Lrp10 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of LRP10 mRNA | CTD | PMID:26290441 | Lrp10 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Lrp10 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LRP10 mRNA | CTD | PMID:21570461 | Lrp10 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of LRP10 mRNA | CTD | PMID:21346803 | Lrp10 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LRP10 mRNA | CTD | PMID:28628672 | Lrp10 | Rat | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Lrp10 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of LRP10 mRNA | CTD | PMID:18648102 | Lrp10 | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Lrp10 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of LRP10 mRNA | CTD | PMID:39298647 | Lrp10 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of LRP10 mRNA | CTD | PMID:30047161 | Lrp10 | Rat | aflatoxin B1 | affects expression | ISO | LRP10 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of LRP10 protein | CTD | PMID:20106945 | Lrp10 | Rat | aflatoxin B1 | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of LRP10 mRNA | CTD | PMID:21632981 and PMID:21641981 | Lrp10 | Rat | all-trans-retinoic acid | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of LRP10 mRNA | CTD | PMID:21934132 more ... | Lrp10 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of LRP10 mRNA | CTD | PMID:30047161 | Lrp10 | Rat | atrazine | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Atrazine results in increased expression of LRP10 mRNA | CTD | PMID:22378314 | Lrp10 | Rat | azathioprine | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Azathioprine results in increased expression of LRP10 mRNA | CTD | PMID:22623647 | Lrp10 | Rat | benzo[a]pyrene | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of LRP10 mRNA | CTD | PMID:20106945 more ... | Lrp10 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Lrp10 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of LRP10 mRNA | CTD | PMID:31163220 | Lrp10 | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Lrp10 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of LRP10 mRNA | CTD | PMID:34319233 | Lrp10 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | Lrp10 (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in increased expression of LRP10 mRNA | CTD | PMID:33754040 | Lrp10 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LRP10 mRNA | CTD | PMID:25181051 and PMID:34947998 | Lrp10 | Rat | bisphenol A | increases expression | ISO | Lrp10 (Mus musculus) | 6480464 | bisphenol A results in increased expression of LRP10 mRNA | CTD | PMID:32156529 and PMID:33221593 | Lrp10 | Rat | bisphenol A | affects expression | ISO | LRP10 (Homo sapiens) | 6480464 | bisphenol A affects the expression of LRP10 mRNA | CTD | PMID:30903817 | Lrp10 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of LRP10 gene | CTD | PMID:28505145 | Lrp10 | Rat | bisphenol F | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LRP10 mRNA | CTD | PMID:28628672 | Lrp10 | Rat | butanal | decreases expression | ISO | LRP10 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of LRP10 mRNA | CTD | PMID:26079696 | Lrp10 | Rat | cadmium dichloride | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of LRP10 mRNA | CTD | PMID:38568856 | Lrp10 | Rat | calcitriol | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of LRP10 mRNA | CTD | PMID:21592394 | Lrp10 | Rat | calcitriol | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of LRP10 mRNA | CTD | PMID:21592394 | Lrp10 | Rat | CGP 52608 | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LRP10 gene] | CTD | PMID:28238834 | Lrp10 | Rat | chlorpyrifos | increases expression | ISO | Lrp10 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of LRP10 mRNA | CTD | PMID:37019170 | Lrp10 | Rat | cisplatin | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of LRP10 mRNA | CTD | PMID:27392435 | Lrp10 | Rat | cisplatin | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of LRP10 mRNA | CTD | PMID:27392435 | Lrp10 | Rat | clozapine | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Clozapine results in increased expression of LRP10 protein | CTD | PMID:36482696 | Lrp10 | Rat | copper(II) chloride | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | cupric chloride results in increased expression of LRP10 mRNA | CTD | PMID:38568856 | Lrp10 | Rat | copper(II) sulfate | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of LRP10 mRNA | CTD | PMID:19549813 | Lrp10 | Rat | coumestrol | decreases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of LRP10 mRNA | CTD | PMID:19167446 | Lrp10 | Rat | Cuprizon | increases expression | EXP | | 6480464 | Cuprizone results in increased expression of LRP10 mRNA | CTD | PMID:26577399 | Lrp10 | Rat | cyclosporin A | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of LRP10 mRNA | CTD | PMID:20106945 and PMID:25562108 | Lrp10 | Rat | DDE | decreases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in decreased expression of LRP10 mRNA | CTD | PMID:38568856 | Lrp10 | Rat | dexamethasone | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LRP10 mRNA | CTD | PMID:28628672 | Lrp10 | Rat | disodium selenite | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of LRP10 mRNA | CTD | PMID:18175754 | Lrp10 | Rat | dorsomorphin | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Lrp10 | Rat | ethyl methanesulfonate | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of LRP10 mRNA | CTD | PMID:23649840 | Lrp10 | Rat | fenthion | decreases expression | ISO | Lrp10 (Mus musculus) | 6480464 | Fenthion results in decreased expression of LRP10 mRNA | CTD | PMID:34813904 | Lrp10 | Rat | folic acid | multiple interactions | ISO | Lrp10 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in increased expression of LRP10 mRNA] | CTD | PMID:22206623 | Lrp10 | Rat | formaldehyde | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of LRP10 mRNA | CTD | PMID:23649840 | Lrp10 | Rat | hydralazine | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of LRP10 mRNA | CTD | PMID:17183730 | Lrp10 | Rat | indometacin | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of LRP10 mRNA | CTD | PMID:28628672 | Lrp10 | Rat | inulin | multiple interactions | ISO | Lrp10 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of LRP10 mRNA | CTD | PMID:36331819 | Lrp10 | Rat | mercury dibromide | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of LRP10 mRNA | CTD | PMID:26272509 | Lrp10 | Rat | mercury dibromide | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LRP10 mRNA | CTD | PMID:27188386 | Lrp10 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of LRP10 mRNA | CTD | PMID:30047161 | Lrp10 | Rat | methyl methanesulfonate | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of LRP10 mRNA | CTD | PMID:23649840 | Lrp10 | Rat | methylmercury chloride | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of LRP10 mRNA | CTD | PMID:28001369 | Lrp10 | Rat | niclosamide | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of LRP10 mRNA | CTD | PMID:36318118 | Lrp10 | Rat | nitrates | multiple interactions | ISO | Lrp10 (Mus musculus) | 6480464 | [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of LRP10 mRNA | CTD | PMID:35964746 | Lrp10 | Rat | ozone | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of LRP10 mRNA | CTD | PMID:35430440 | Lrp10 | Rat | paracetamol | affects expression | ISO | Lrp10 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LRP10 mRNA | CTD | PMID:17562736 | Lrp10 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of LRP10 mRNA | CTD | PMID:33387578 | Lrp10 | Rat | paracetamol | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of LRP10 mRNA | CTD | PMID:22230336 and PMID:26690555 | Lrp10 | Rat | paracetamol | decreases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LRP10 mRNA | CTD | PMID:21420995 | Lrp10 | Rat | pentane-2,3-dione | increases expression | EXP | | 6480464 | 2 and 3-pentanedione results in increased expression of LRP10 mRNA | CTD | PMID:25710175 | Lrp10 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Lrp10 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of LRP10 mRNA | CTD | PMID:36331819 | Lrp10 | Rat | phenylmercury acetate | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of LRP10 mRNA | CTD | PMID:26272509 | Lrp10 | Rat | phenylmercury acetate | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LRP10 mRNA | CTD | PMID:27188386 | Lrp10 | Rat | quercetin | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Quercetin results in increased expression of LRP10 mRNA | CTD | PMID:21632981 | Lrp10 | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of LRP10 mRNA | CTD | PMID:28374803 | Lrp10 | Rat | SB 431542 | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Lrp10 | Rat | silicon dioxide | decreases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of LRP10 mRNA | CTD | PMID:25895662 | Lrp10 | Rat | sodium arsenite | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of LRP10 mRNA | CTD | PMID:38568856 | Lrp10 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of LRP10 mRNA | CTD | PMID:30047161 | Lrp10 | Rat | sulforaphane | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | sulforaphane results in increased expression of LRP10 mRNA | CTD | PMID:26833863 | Lrp10 | Rat | temozolomide | decreases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of LRP10 mRNA | CTD | PMID:31758290 | Lrp10 | Rat | testosterone | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of LRP10 mRNA | CTD | PMID:21592394 | Lrp10 | Rat | testosterone | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Testosterone results in increased expression of LRP10 mRNA | CTD | PMID:21592394 | Lrp10 | Rat | titanium dioxide | increases expression | ISO | Lrp10 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of LRP10 mRNA | CTD | PMID:29264374 | Lrp10 | Rat | titanium dioxide | decreases methylation | ISO | Lrp10 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of LRP10 gene and titanium dioxide results in decreased methylation of LRP10 promoter | CTD | PMID:35295148 | Lrp10 | Rat | trichostatin A | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of LRP10 mRNA | CTD | PMID:24935251 and PMID:26272509 | Lrp10 | Rat | trichostatin A | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of LRP10 mRNA | CTD | PMID:27188386 | Lrp10 | Rat | triphenyl phosphate | affects expression | ISO | LRP10 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of LRP10 mRNA | CTD | PMID:37042841 | Lrp10 | Rat | valproic acid | increases methylation | ISO | LRP10 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of LRP10 gene | CTD | PMID:29154799 | Lrp10 | Rat | valproic acid | increases expression | ISO | LRP10 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LRP10 mRNA | CTD | PMID:19101580 more ... | Lrp10 | Rat | valproic acid | multiple interactions | ISO | LRP10 (Homo sapiens) | 6480464 | [Hydralazine co-treated with Valproic Acid] results in increased expression of LRP10 mRNA more ... | CTD | PMID:17183730 and PMID:27188386 | Lrp10 | Rat | valproic acid | increases expression | ISO | Lrp10 (Mus musculus) | 6480464 | Valproic Acid results in increased expression of LRP10 mRNA | CTD | PMID:19136453 | Lrp10 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of LRP10 mRNA | CTD | PMID:22570695 | Lrp10 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of LRP10 mRNA | CTD | PMID:23034163 | |