Atp8a2 (ATPase phospholipid transporting 8A2) - Rat Genome Database
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Gene: Atp8a2 (ATPase phospholipid transporting 8A2) Rattus norvegicus
Analyze
Symbol: Atp8a2
Name: ATPase phospholipid transporting 8A2
RGD ID: 1594597
Description: Predicted to have ATPase activity. Involved in neuron projection development. Predicted to localize to Golgi apparatus; nucleoplasm; and plasma membrane. Human ortholog(s) of this gene implicated in cerebellar ataxia, mental retardation and dysequlibrium syndrome. Orthologous to human ATP8A2 (ATPase phospholipid transporting 8A2); INTERACTS WITH 17alpha-ethynylestradiol; bisphenol A; valproic acid.
Type: protein-coding
RefSeq Status: MODEL
Also known as: ATPase, aminophospholipid transporter, class I, type 8A, member 2; LOC691889; phospholipid-transporting ATPase IB; similar to ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21533,817,309 - 34,350,193 (-)NCBI
Rnor_6.0 Ensembl1540,000,322 - 40,428,800 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01539,955,689 - 40,488,737 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01543,781,312 - 44,300,886 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41538,759,902 - 39,271,237 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1533,526,116 - 34,051,833 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:1634998   PMID:20947505   PMID:22912588   PMID:24413176  


Genomics

Comparative Map Data
Atp8a2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21533,817,309 - 34,350,193 (-)NCBI
Rnor_6.0 Ensembl1540,000,322 - 40,428,800 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01539,955,689 - 40,488,737 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01543,781,312 - 44,300,886 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41538,759,902 - 39,271,237 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1533,526,116 - 34,051,833 (-)NCBICelera
Cytogenetic Map15p12NCBI
ATP8A2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1325,371,974 - 26,025,851 (+)EnsemblGRCh38hg38GRCh38
GRCh381325,371,974 - 26,025,851 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371325,946,112 - 26,599,989 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361324,844,209 - 25,493,420 (+)NCBINCBI36hg18NCBI36
Build 341324,941,114 - 25,492,996NCBI
Celera137,010,413 - 7,663,625 (+)NCBI
Cytogenetic Map13q12.13NCBI
HuRef136,857,229 - 7,413,507 (+)NCBIHuRef
CHM1_11325,914,326 - 26,568,138 (+)NCBICHM1_1
LOC108168164
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391460,423,607 - 60,434,657 (-)NCBIGRCm39mm39
GRCm381460,186,158 - 60,197,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1459,638,540 - 60,197,179 (-)EnsemblGRCm38mm10GRCm38
MGSCv371460,266,578 - 60,705,671 (-)NCBIGRCm37mm9NCBIm37
MGSCv361458,601,851 - 59,040,944 (-)NCBImm8
Celera1457,450,161 - 57,876,764 (-)NCBICelera
Cytogenetic Map14D1NCBI
ATP8A2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11325,111,454 - 25,668,526 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1325,111,653 - 25,662,668 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0136,663,888 - 7,319,094 (+)NCBIMhudiblu_PPA_v0panPan3
ATP8A2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2513,495,970 - 14,066,513 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12513,490,550 - 14,066,942 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Atp8a2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936688299,831 - 925,444 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LOC100523747
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl113,278,071 - 3,793,881 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1113,277,395 - 3,793,881 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2112,576,600 - 2,969,328 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ATP8A2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.134,747,744 - 5,378,598 (+)NCBI
ChlSab1.1 Ensembl34,747,882 - 5,323,235 (+)Ensembl
Atp8a2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477612,474,442 - 13,126,237 (-)NCBI

Position Markers
D15Got23  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01540,269,617 - 40,269,718NCBIRnor6.0
Rnor_5.01544,083,263 - 44,083,364UniSTSRnor5.0
Celera1533,834,224 - 33,834,325UniSTS
RH 3.4 Map15230.5RGD
RH 3.4 Map15230.5UniSTS
Cytogenetic Map15p12UniSTS
D15Rat87  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01540,049,394 - 40,049,552NCBIRnor6.0
Rnor_5.01543,867,742 - 43,867,900UniSTSRnor5.0
RGSC_v3.41538,847,197 - 38,847,355UniSTSRGSC3.4
Celera1533,619,835 - 33,619,995UniSTS
Cytogenetic Map15p12UniSTS
RH144321  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01540,195,468 - 40,195,621NCBIRnor6.0
Rnor_5.01544,009,114 - 44,009,267UniSTSRnor5.0
RGSC_v3.41538,995,971 - 38,996,124UniSTSRGSC3.4
Celera1533,762,294 - 33,762,447UniSTS
RH 3.4 Map15218.3UniSTS
Cytogenetic Map15p12UniSTS
BI277866  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01539,964,624 - 39,964,777NCBIRnor6.0
Rnor_5.01543,782,761 - 43,782,914UniSTSRnor5.0
RGSC_v3.41538,760,040 - 38,760,193UniSTSRGSC3.4
Celera1533,535,051 - 33,535,204UniSTS
RH 3.4 Map15217.5UniSTS
Cytogenetic Map15p12UniSTS
BQ210369  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01539,975,854 - 39,976,063NCBIRnor6.0
Rnor_5.01543,793,855 - 43,794,064UniSTSRnor5.0
RGSC_v3.41538,771,134 - 38,771,343UniSTSRGSC3.4
Celera1533,546,313 - 33,546,522UniSTS
RH 3.4 Map15217.7UniSTS
Cytogenetic Map15p12UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15142844179Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15143521446Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15162301382Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15232787753535766Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15388113148881131Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151071919155719191Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151549236072568189Rat
9590272Scort14Serum corticosterone level QTL 142.780.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)151698090761980907Rat
8694427Bw163Body weight QTL 1634.820.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)151698090761980907Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151724964162249641Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151724964162249641Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151724964162249641Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151809320881255430Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151851391388036354Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152102134241082727Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152102134252831189Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152377896946825072Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1526381041106550657Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1526381041106550657Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1526381041106550657Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152870974173709741Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)153321910189640841Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)153321910189640841Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)153321910189640841Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)153321910189640841Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)153321910189640841Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)153948079762596410Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153974955779033707Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153974955779033707Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:71
Count of miRNA genes:59
Interacting mature miRNAs:63
Transcripts:ENSRNOT00000011451, ENSRNOT00000051937
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 58 7
Low 3 26 50 34 18 34 1 1 14 24 20 7 1
Below cutoff 14 5 5 1 5 7 8 2 11 14 3 7

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_003751492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093998 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093999 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039094005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC126002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000011451   ⟹   ENSRNOP00000011451
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1540,000,322 - 40,428,800 (-)Ensembl
RefSeq Acc Id: XM_003751492   ⟹   XP_003751540
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,328,616 (-)NCBI
Rnor_6.01539,955,689 - 40,466,848 (-)NCBI
Rnor_5.01543,781,312 - 44,300,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_003752815   ⟹   XP_003752863
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1533,526,116 - 33,955,920 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221968   ⟹   XP_006222030
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1533,526,116 - 33,982,217 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221970   ⟹   XP_006222032
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1533,526,116 - 34,051,833 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006221972   ⟹   XP_006222034
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1533,526,116 - 34,031,491 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252160   ⟹   XP_006252222
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01539,955,689 - 40,417,907 (-)NCBI
Rnor_5.01543,781,312 - 44,300,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252164   ⟹   XP_006252226
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01539,955,689 - 40,468,295 (-)NCBI
Rnor_5.01543,781,312 - 44,300,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252165   ⟹   XP_006252227
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01539,955,689 - 40,391,575 (-)NCBI
Rnor_5.01543,781,312 - 44,300,886 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769169   ⟹   XP_008767391
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1533,526,116 - 34,005,962 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008769177   ⟹   XP_008767399
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Celera1533,526,116 - 33,972,219 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770789   ⟹   XP_008769011
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01539,955,689 - 40,442,015 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008770790   ⟹   XP_008769012
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01539,955,689 - 40,407,883 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017599897   ⟹   XP_017455386
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01539,955,689 - 40,488,737 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093993   ⟹   XP_038949921
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,328,616 (-)NCBI
RefSeq Acc Id: XM_039093994   ⟹   XP_038949922
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,304,389 (-)NCBI
RefSeq Acc Id: XM_039093995   ⟹   XP_038949923
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,280,483 (-)NCBI
RefSeq Acc Id: XM_039093996   ⟹   XP_038949924
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,350,193 (-)NCBI
RefSeq Acc Id: XM_039093997   ⟹   XP_038949925
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,350,193 (-)NCBI
RefSeq Acc Id: XM_039093998   ⟹   XP_038949926
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,318,397 (-)NCBI
RefSeq Acc Id: XM_039093999   ⟹   XP_038949927
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,350,193 (-)NCBI
RefSeq Acc Id: XM_039094000   ⟹   XP_038949928
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,303,379 (-)NCBI
RefSeq Acc Id: XM_039094001   ⟹   XP_038949929
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,255,049 (-)NCBI
RefSeq Acc Id: XM_039094002   ⟹   XP_038949930
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,328,998 (-)NCBI
RefSeq Acc Id: XM_039094003   ⟹   XP_038949931
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21533,817,309 - 34,328,616 (-)NCBI
RefSeq Acc Id: XM_039094004   ⟹   XP_038949932
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21534,081,745 - 34,328,616 (-)NCBI
RefSeq Acc Id: XM_039094005   ⟹   XP_038949933
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21534,143,714 - 34,328,616 (-)NCBI
Reference Sequences
RefSeq Acc Id: XP_003751540   ⟸   XM_003751492
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_003752863   ⟸   XM_003752815
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006222032   ⟸   XM_006221970
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006222034   ⟸   XM_006221972
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006222030   ⟸   XM_006221968
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006252226   ⟸   XM_006252164
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_006252222   ⟸   XM_006252160
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006252227   ⟸   XM_006252165
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008767391   ⟸   XM_008769169
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008767399   ⟸   XM_008769177
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008769011   ⟸   XM_008770789
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_008769012   ⟸   XM_008770790
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_017455386   ⟸   XM_017599897
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000011451   ⟸   ENSRNOT00000011451
RefSeq Acc Id: XP_038949927   ⟸   XM_039093999
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038949924   ⟸   XM_039093996
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038949925   ⟸   XM_039093997
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038949930   ⟸   XM_039094002
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038949931   ⟸   XM_039094003
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038949921   ⟸   XM_039093993
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949926   ⟸   XM_039093998
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038949922   ⟸   XM_039093994
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038949928   ⟸   XM_039094000
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038949923   ⟸   XM_039093995
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038949929   ⟸   XM_039094001
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038949932   ⟸   XM_039094004
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038949933   ⟸   XM_039094005
- Peptide Label: isoform X8
Protein Domains
PhoLip_ATPase_C   PhoLip_ATPase_N

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Damaging Variants


Assembly: Rnor_5.0
Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Strain
15 43977841 43977842 C T snv SDLEF7/Barth (UDEL)


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1594597 AgrOrtholog
Ensembl Genes ENSRNOG00000008053 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000011451 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011451 UniProtKB/TrEMBL
Gene3D-CATH 3.40.1110.10 UniProtKB/TrEMBL
  3.40.50.1000 UniProtKB/TrEMBL
InterPro ATPase_P-typ_cyto_domN UniProtKB/TrEMBL
  ATPase_P-typ_P_site UniProtKB/TrEMBL
  ATPase_P-typ_Plipid-transl UniProtKB/TrEMBL
  ATPase_P-typ_TM_dom UniProtKB/TrEMBL
  ATPase_P-typ_transduc_dom_A UniProtKB/TrEMBL
  Cation_transp_P_typ_ATPase UniProtKB/TrEMBL
  HAD-like_dom UniProtKB/TrEMBL
  HAD-like_sf UniProtKB/TrEMBL
  P-type_ATPase_N UniProtKB/TrEMBL
  P_typ_ATPase_c UniProtKB/TrEMBL
NCBI Gene 691889 ENTREZGENE
PANTHER PTHR24092 UniProtKB/TrEMBL
Pfam PhoLip_ATPase_C UniProtKB/TrEMBL
  PhoLip_ATPase_N UniProtKB/TrEMBL
PhenoGen Atp8a2 PhenoGen
PROSITE ATPASE_E1_E2 UniProtKB/TrEMBL
Superfamily-SCOP ATPase_cation_domN UniProtKB/TrEMBL
  HAD-like_dom UniProtKB/TrEMBL
  SSF81653 UniProtKB/TrEMBL
  SSF81665 UniProtKB/TrEMBL
TIGRFAMs ATPase-Plipid UniProtKB/TrEMBL
  ATPase_P-type UniProtKB/TrEMBL
UniProt D4A3X6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-17 Atp8a2  ATPase phospholipid transporting 8A2  Atp8a2  ATPase, aminophospholipid transporter, class I, type 8A, member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-09-17 Atp8a2  ATPase, aminophospholipid transporter, class I, type 8A, member 2  LOC691889  similar to ATPase, aminophospholipid transporter-like, class I, type 8A, member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC691889  similar to ATPase, aminophospholipid transporter-like, class I, type 8A, member 2  LOC682925  similar to ATPase, aminophospholipid transporter-like, Class I, type 8A, member 2  Data Merged 1643240 APPROVED
2006-11-20 LOC691889  similar to ATPase, aminophospholipid transporter-like, class I, type 8A, member 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC682925  similar to ATPase, aminophospholipid transporter-like, Class I, type 8A, member 2      Symbol and Name status set to provisional 70820 PROVISIONAL