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Gene: Gjb6 (gap junction protein, beta 6) Rattus norvegicus
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Symbol: Gjb6
Name: gap junction protein, beta 6
Description: Predicted to have cytoskeletal protein binding activity and gap junction channel activity involved in cell communication by electrical coupling. Involved in several processes, including cellular response to glucose stimulus; response to electrical stimulus; and response to lipopolysaccharide. Localizes to apical plasma membrane; cytosol; and gap junction. Biomarker of borna disease; status epilepticus; transient cerebral ischemia; ureteral obstruction; and visual epilepsy. Human ortholog(s) of this gene implicated in Clouston syndrome; autosomal dominant nonsyndromic deafness 3B; autosomal recessive nonsyndromic deafness 1A; autosomal recessive nonsyndromic deafness 1B; and ectodermal dysplasia. Orthologous to human GJB6 (gap junction protein beta 6); INTERACTS WITH 1,3-dinitrobenzene; 6-propyl-2-thiouracil; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: connexin f; Cx30; Cxnf; gap junction beta-6 protein; gap junction membrane channel protein beta 6; gap junction protein, beta 6 (connexin 30)
Orthologs:
Homo sapiens (human) : GJB6 (gap junction protein beta 6)  HGNC  Alliance
Mus musculus (house mouse) : Gjb6 (gap junction protein, beta 6)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gjb6 (gap junction protein beta 6)
Pan paniscus (bonobo/pygmy chimpanzee) : GJB6 (gap junction protein beta 6)
Canis lupus familiaris (dog) : GJB6 (gap junction protein beta 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gjb6 (gap junction protein beta 6)
Sus scrofa (pig) : GJB6 (gap junction protein beta 6)
Chlorocebus sabaeus (African green monkey) : GJB6 (gap junction protein beta 6)
Heterocephalus glaber (naked mole-rat) : Gjb6 (gap junction protein beta 6)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01537,400,888 - 37,411,656 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1537,400,889 - 37,410,848 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01541,248,072 - 41,258,522 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41536,177,736 - 36,186,513 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11536,193,435 - 36,202,213 (-)NCBI
Celera1530,996,679 - 31,005,456 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gjb6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621830
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.