LOC100361866 (eosinophil cationic protein-like) - Rat Genome Database

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Gene: LOC100361866 (eosinophil cationic protein-like) Rattus norvegicus
Analyze
No known orthologs.
Symbol: LOC100361866
Name: eosinophil cationic protein-like
RGD ID: 2319312
Description: Predicted to enable endonuclease activity and nucleic acid binding activity. Orthologous to human RNASE2 (ribonuclease A family member 2) and RNASE3 (ribonuclease A family member 3).
Type: protein-coding
RefSeq Status: VALIDATED
RGD Orthologs
Alliance Orthologs
More Info homologs ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81527,009,206 - 27,010,076 (-)NCBIGRCr8
mRatBN7.21524,535,701 - 24,536,571 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1524,535,700 - 24,536,592 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01528,240,548 - 28,241,466 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1528,240,731 - 28,241,198 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01532,046,718 - 32,047,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,272,317 - 27,272,784 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model



Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC100361866Ratchemotaxis involved_inIBAMGI:108020 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC100361866Ratdefense response to Gram-positive bacterium involved_inIBAMGI:1925666 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
LOC100361866Ratinnate immune response in mucosa involved_inIBAPANTHER:PTN000153602 and UniProtKB:P127241600115GO_REF:0000033GO_CentralGO_REF:0000033

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC100361866Ratextracellular space is_active_inIBAPANTHER:PTN000153602 and UniProtKB:P127241600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
LOC100361866Ratendonuclease activity enablesIEAUniProtKB-KW:KW-02551600115GO_REF:0000043UniProtGO_REF:0000043
LOC100361866Rathydrolase activity enablesIEAUniProtKB-KW:KW-03781600115GO_REF:0000043UniProtGO_REF:0000043
LOC100361866Ratnuclease activity enablesIEAUniProtKB-KW:KW-05401600115GO_REF:0000043UniProtGO_REF:0000043
LOC100361866Ratnucleic acid binding enablesIEAInterPro:IPR0014271600115GO_REF:0000002InterProGO_REF:0000002
LOC100361866RatRNA nuclease activity enablesIBAMGI:104984 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions


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1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat

1 to 10 of 25 rows



alimentary part of gastrointestinal system
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
4 3 30 39 41 18 12 18 12 55 30 11 3 25 23


RefSeq Transcripts NM_001408969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC094516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000015 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000086535   ⟹   ENSRNOP00000072837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1528,240,731 - 28,241,198 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105605   ⟹   ENSRNOP00000076490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1524,535,700 - 24,536,592 (-)Ensembl
RefSeq Acc Id: NM_001408969   ⟹   NP_001395898
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81527,009,206 - 27,010,076 (-)NCBI
mRatBN7.21524,535,701 - 24,536,571 (-)NCBI
Protein RefSeqs NP_001395898 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000084145
Ensembl Acc Id: ENSRNOP00000072837   ⟸   ENSRNOT00000086535
Ensembl Acc Id: ENSRNOP00000076490   ⟸   ENSRNOT00000105605
RefSeq Acc Id: NP_001395898   ⟸   NM_001408969
- Peptide Label: precursor
- UniProtKB: P70709 (UniProtKB/Swiss-Prot),   W0UVG3 (UniProtKB/TrEMBL),   Q9R130 (UniProtKB/TrEMBL)
Ribonuclease A-domain

Name Modeler Protein Id AA Range Protein Structure
AF-P70709-F1-model_v2 AlphaFold P70709 1-155 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 26 of 26 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14007 BioCyc
Ensembl Genes ENSRNOG00000053457 Ensembl
  ENSRNOG00000068464 Ensembl
  ENSRNOG00000085776 ENTREZGENE
Ensembl Transcript ENSRNOT00000119723 ENTREZGENE
Gene3D-CATH Ribonuclease A-like domain UniProtKB/TrEMBL
InterPro RNaseA UniProtKB/TrEMBL
  RNaseA-like_dom_sf UniProtKB/TrEMBL
  RNaseA_AS UniProtKB/TrEMBL
  RNaseA_domain UniProtKB/TrEMBL
NCBI Gene 100361866 ENTREZGENE
PANTHER EOSINOPHIL CATIONIC PROTEIN UniProtKB/TrEMBL
  RIBONUCLEASE UniProtKB/TrEMBL
Pfam RnaseA UniProtKB/TrEMBL
PhenoGen LOC100361866 PhenoGen
PRINTS RIBONUCLEASE UniProtKB/TrEMBL
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  RNASE_PANCREATIC UniProtKB/TrEMBL
RatGTEx ENSRNOG00000053457 RatGTEx
  ENSRNOG00000068464 RatGTEx
  ENSRNOG00000085776 RatGTEx
SMART RNAse_Pc UniProtKB/TrEMBL
Superfamily-SCOP RNase A-like UniProtKB/TrEMBL
UniProt P70709 ENTREZGENE
  Q9R130 ENTREZGENE, UniProtKB/TrEMBL
  W0UVG3 ENTREZGENE
1 to 26 of 26 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 LOC100361866  eosinophil cationic protein-like      Symbol and Name status set to provisional 70820 PROVISIONAL