Ptger2 (prostaglandin E receptor 2) - Rat Genome Database

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Gene: Ptger2 (prostaglandin E receptor 2) Rattus norvegicus
Analyze
Symbol: Ptger2
Name: prostaglandin E receptor 2
RGD ID: 620020
Description: Enables prostaglandin E receptor activity. Involved in positive regulation of gastric mucosal blood circulation. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Orthologous to human PTGER2 (prostaglandin E receptor 2); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: EP2; LOC100360765; PGE receptor EP2 subtype; PGE receptor, EP2 subtype; PGE2 receptor EP2 subtype; prostaglandin E receptor 2 (subtype EP2); prostaglandin E receptor EP2 subtype; prostaglandin E2 receptor EP2 subtype; prostaglandin E2 receptor EP2 subtype-like; prostaglandin E2 receptor type 2; prostanoid EP2 receptor; Ptger-ep2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81520,694,765 - 20,708,475 (+)NCBIGRCr8
mRatBN7.21518,215,013 - 18,228,714 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1518,217,285 - 18,228,714 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1521,008,805 - 21,020,249 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01521,965,749 - 21,977,190 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01520,222,303 - 20,233,747 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01519,336,029 - 19,349,759 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1519,338,175 - 19,350,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01523,301,463 - 23,315,207 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41520,205,443 - 20,216,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11520,878,084 - 20,889,615 (+)NCBI
Celera1518,649,190 - 18,660,619 (+)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-bis(4-hydroxyphenyl)propionitrile  (EXP)
2,4,6-trinitrobenzenesulfonic acid  (EXP)
3',5'-cyclic AMP  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acetylsalicylic acid  (ISO)
AH23848  (ISO)
all-trans-retinoic acid  (ISO)
alternariol  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (ISO)
asbestos  (ISO)
bellidifolin  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
Cryptotanshinone  (ISO)
D-penicillamine  (EXP)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP,ISO)
dichloromethane  (ISO)
diosmin  (ISO)
dioxygen  (EXP)
disodium selenite  (ISO)
diuron  (EXP)
ethylbenzene  (ISO)
fonofos  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
hemin  (ISO)
ibuprofen  (ISO)
indometacin  (ISO)
inulin  (ISO)
ketoconazole  (ISO)
levonorgestrel  (ISO)
lipopolysaccharide  (EXP,ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
methylisothiazolinone  (ISO)
mifepristone  (EXP)
misoprostol  (ISO)
mono(2-ethylhexyl) phthalate  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
nickel atom  (ISO)
nickel sulfate  (ISO)
Nonylphenol  (EXP)
NS-398  (EXP,ISO)
o-xylene  (ISO)
oxaliplatin  (EXP)
paraquat  (EXP)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
progesterone  (EXP,ISO)
propanal  (ISO)
prostaglandin D2  (ISO)
prostaglandin E2  (EXP,ISO)
prostaglandin F2alpha  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
selenic acid  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium hydrogensulfite  (EXP)
sodium sulfite  (EXP)
sulfur dioxide  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
terbinafine  (ISO)
terbufos  (ISO)
testosterone  (EXP)
testosterone undecanoate  (ISO)
tetrachloromethane  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene  (ISO)
topotecan  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinyl carbamate  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
plasma membrane  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach. Araki H, etal., Aliment Pharmacol Ther. 2000 Apr;14 Suppl 1:116-24.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Molecular cloning and expression of a rat prostaglandin E2 receptor of the EP2 subtype. Nemoto K, etal., Prostaglandins 1997 Oct;54(4):713-25.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9537820   PMID:10684792   PMID:11533709   PMID:12939279   PMID:14552899   PMID:14606517   PMID:15834430   PMID:16136483   PMID:16437207   PMID:16546360   PMID:16646980   PMID:17058034  
PMID:17947453   PMID:18403039   PMID:18684231   PMID:19524109   PMID:19555672   PMID:19712723   PMID:20713561   PMID:21716255   PMID:21768374   PMID:21939736   PMID:22061836   PMID:22789984  
PMID:23404506   PMID:24146253   PMID:24253784   PMID:25059824   PMID:25715797   PMID:28717970   PMID:28759126   PMID:32165825   PMID:36889213  


Genomics

Comparative Map Data
Ptger2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81520,694,765 - 20,708,475 (+)NCBIGRCr8
mRatBN7.21518,215,013 - 18,228,714 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1518,217,285 - 18,228,714 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1521,008,805 - 21,020,249 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01521,965,749 - 21,977,190 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01520,222,303 - 20,233,747 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01519,336,029 - 19,349,759 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1519,338,175 - 19,350,210 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01523,301,463 - 23,315,207 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41520,205,443 - 20,216,872 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11520,878,084 - 20,889,615 (+)NCBI
Celera1518,649,190 - 18,660,619 (+)NCBICelera
Cytogenetic Map15p14NCBI
PTGER2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381452,314,312 - 52,328,598 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1452,314,305 - 52,329,822 (+)EnsemblGRCh38hg38GRCh38
GRCh371452,781,030 - 52,795,316 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361451,850,863 - 51,865,074 (+)NCBINCBI36Build 36hg18NCBI36
Build 341451,850,862 - 51,865,070NCBI
Celera1432,648,601 - 32,662,908 (+)NCBICelera
Cytogenetic Map14q22.1NCBI
HuRef1432,941,341 - 32,955,648 (+)NCBIHuRef
CHM1_11452,720,192 - 52,734,499 (+)NCBICHM1_1
T2T-CHM13v2.01446,521,407 - 46,535,692 (+)NCBIT2T-CHM13v2.0
Ptger2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391445,225,568 - 45,241,277 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1445,225,652 - 45,241,277 (+)EnsemblGRCm39 Ensembl
GRCm381444,988,111 - 45,003,820 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1444,988,195 - 45,003,820 (+)EnsemblGRCm38mm10GRCm38
MGSCv371445,607,786 - 45,623,495 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361443,910,468 - 43,925,027 (+)NCBIMGSCv36mm8
Celera1441,179,301 - 41,195,008 (+)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1422.68NCBI
Ptger2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540910,757,888 - 10,774,688 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540910,760,801 - 10,775,197 (-)NCBIChiLan1.0ChiLan1.0
PTGER2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21553,441,812 - 53,459,334 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11452,661,559 - 52,676,942 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01432,910,755 - 32,926,138 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11451,195,381 - 51,209,686 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1451,195,381 - 51,209,686 (+)Ensemblpanpan1.1panPan2
PTGER2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1828,523,318 - 28,536,936 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl828,522,681 - 28,536,922 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha828,274,789 - 28,288,408 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0828,698,142 - 28,712,635 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl828,699,025 - 28,712,635 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1828,369,315 - 28,383,055 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0828,428,898 - 28,442,522 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0828,777,540 - 28,791,160 (+)NCBIUU_Cfam_GSD_1.0
Ptger2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864076,666,763 - 76,679,725 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366972,440,901 - 2,453,975 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366972,440,943 - 2,453,897 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGER2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1181,994,560 - 182,009,953 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11181,993,961 - 182,009,959 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21202,268,089 - 202,282,621 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGER2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12429,395,799 - 29,410,723 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2429,396,464 - 29,409,575 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605317,664,018 - 17,678,316 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ptger2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473116,726,975 - 16,741,557 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473116,729,846 - 16,741,529 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ptger2
59 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:43
Count of miRNA genes:41
Interacting mature miRNAs:42
Transcripts:ENSRNOT00000075209
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat

Markers in Region
RH134047  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21518,228,901 - 18,229,081 (+)MAPPERmRatBN7.2
Rnor_6.01519,349,947 - 19,350,126NCBIRnor6.0
Rnor_5.01523,315,395 - 23,315,574UniSTSRnor5.0
RGSC_v3.41520,889,803 - 20,889,982UniSTSRGSC3.4
RGSC_v3.41520,217,060 - 20,217,239UniSTSRGSC3.4
Celera1518,660,807 - 18,660,986UniSTS
RH 3.4 Map15149.7UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 6 42 113 90 89 58 25 58 6 205 88 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000075209   ⟹   ENSRNOP00000064907
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1518,217,285 - 18,228,714 (+)Ensembl
Rnor_6.0 Ensembl1519,338,175 - 19,350,210 (+)Ensembl
RefSeq Acc Id: NM_031088   ⟹   NP_112350
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81520,697,046 - 20,708,475 (+)NCBI
mRatBN7.21518,217,285 - 18,228,714 (+)NCBI
Rnor_6.01519,338,330 - 19,349,759 (+)NCBI
Rnor_5.01523,301,463 - 23,315,207 (+)NCBI
RGSC_v3.41520,205,443 - 20,216,872 (+)RGD
Celera1518,649,190 - 18,660,619 (+)RGD
Sequence:
RefSeq Acc Id: XM_039093687   ⟹   XP_038949615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81520,694,771 - 20,701,592 (+)NCBI
mRatBN7.21518,215,015 - 18,222,120 (+)NCBI
RefSeq Acc Id: XR_001841264
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81520,694,765 - 20,708,145 (+)NCBI
mRatBN7.21518,215,013 - 18,228,384 (+)NCBI
Rnor_6.01519,336,029 - 19,349,361 (+)NCBI
Sequence:
RefSeq Acc Id: NP_112350   ⟸   NM_031088
- UniProtKB: Q547S0 (UniProtKB/Swiss-Prot),   Q62928 (UniProtKB/Swiss-Prot),   A6KDY9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064907   ⟸   ENSRNOT00000075209
RefSeq Acc Id: XP_038949615   ⟸   XM_039093687
- Peptide Label: isoform X1
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q62928-F1-model_v2 AlphaFold Q62928 1-357 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620020 AgrOrtholog
BioCyc Gene G2FUF-14230 BioCyc
Ensembl Genes ENSRNOG00000050968 Ensembl, UniProtKB/Swiss-Prot
  ENSRNOG00055026775 UniProtKB/Swiss-Prot
  ENSRNOG00060028536 UniProtKB/Swiss-Prot
  ENSRNOG00065008656 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000075209.3 UniProtKB/Swiss-Prot
  ENSRNOT00055046233 UniProtKB/Swiss-Prot
  ENSRNOT00060049603 UniProtKB/Swiss-Prot
  ENSRNOT00065013735 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostanoid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostglndn_EP2_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81752 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 81752 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR FAMILY 1 MEMBER UniProtKB/TrEMBL
  PROSTAGLANDIN E2 RECEPTOR EP2 SUBTYPE UniProtKB/TrEMBL
  PTHR11866 UniProtKB/Swiss-Prot
  PTHR11866:SF8 UniProtKB/Swiss-Prot
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ptger2 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROSTANOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRSTNOIDEP2R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050968 RatGTEx
  ENSRNOG00055026775 RatGTEx
  ENSRNOG00060028536 RatGTEx
  ENSRNOG00065008656 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6KDY9 ENTREZGENE, UniProtKB/TrEMBL
  PE2R2_RAT UniProtKB/Swiss-Prot
  Q547S0 ENTREZGENE
  Q62928 ENTREZGENE
UniProt Secondary Q547S0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-29 Ptger2  prostaglandin E receptor 2  Ptger2  prostaglandin E receptor 2 (subtype EP2)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Ptger2  prostaglandin E receptor 2 (subtype EP2)  LOC100360765  prostaglandin E2 receptor EP2 subtype-like  Data merged from RGD:2321493 737654 PROVISIONAL
2010-05-06 LOC100360765  prostaglandin E2 receptor EP2 subtype-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-02-24 Ptger2  prostaglandin E receptor 2 (subtype EP2)  Ptger2  prostaglandin E receptor 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Ptger2  prostaglandin E receptor 2, subtype EP2    prostaglandin E receptor EP2 subtype  Name updated 1299863 APPROVED
2002-08-07 Ptger2  prostaglandin E receptor EP2 subtype      Symbol and Name status set to provisional 70820 PROVISIONAL