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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nynrin | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of NYNRIN mRNA | CTD | PMID:29097150 | Nynrin | Rat | 17beta-estradiol | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Estradiol results in decreased expression of NYNRIN mRNA | CTD | PMID:31614463 | Nynrin | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NYNRIN mRNA | CTD | PMID:32109520 | Nynrin | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NYNRIN mRNA | CTD | PMID:33387578 | Nynrin | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Nynrin (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin affects the methylation of NYNRIN intron] which results in decreased expression of NYNRIN mRNA | CTD | PMID:33017471 | Nynrin | Rat | 4,4'-sulfonyldiphenol | affects methylation | ISO | Nynrin (Mus musculus) | 6480464 | bisphenol S affects the methylation of NYNRIN gene | CTD | PMID:31683443 | Nynrin | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Decitabine affects the expression of NYNRIN mRNA | CTD | PMID:23300844 | Nynrin | Rat | acrylamide | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of NYNRIN mRNA | CTD | PMID:32763439 | Nynrin | Rat | aflatoxin B1 | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of NYNRIN mRNA | CTD | PMID:27153756 | Nynrin | Rat | aflatoxin B1 | decreases methylation | ISO | NYNRIN (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of NYNRIN exon and Aflatoxin B1 results in decreased methylation of NYNRIN gene | CTD | PMID:27153756 and PMID:30157460 | Nynrin | Rat | Aflatoxin B2 alpha | decreases methylation | ISO | NYNRIN (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of NYNRIN exon | CTD | PMID:30157460 | Nynrin | Rat | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of NYNRIN mRNA | CTD | PMID:30779732 | Nynrin | Rat | antirheumatic drug | increases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of NYNRIN mRNA | CTD | PMID:24449571 | Nynrin | Rat | arsane | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of NYNRIN mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NYNRIN mRNA | CTD | PMID:39836092 | Nynrin | Rat | arsenic atom | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of NYNRIN mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NYNRIN mRNA | CTD | PMID:39836092 | Nynrin | Rat | benzo[a]pyrene | decreases methylation | ISO | NYNRIN (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of NYNRIN promoter | CTD | PMID:27901495 | Nynrin | Rat | benzo[e]pyrene | decreases methylation | ISO | NYNRIN (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of NYNRIN exon | CTD | PMID:30157460 | Nynrin | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Nynrin (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of NYNRIN mRNA | CTD | PMID:33754040 | Nynrin | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NYNRIN mRNA | CTD | PMID:30816183 | Nynrin | Rat | bisphenol A | increases expression | ISO | Nynrin (Mus musculus) | 6480464 | bisphenol A results in increased expression of NYNRIN mRNA | CTD | PMID:32156529 | Nynrin | Rat | cisplatin | affects expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Cisplatin affects the expression of NYNRIN mRNA | CTD | PMID:23300844 | Nynrin | Rat | cisplatin | decreases phosphorylation | ISO | Nynrin (Mus musculus) | 6480464 | Cisplatin results in decreased phosphorylation of NYNRIN protein | CTD | PMID:22006019 | Nynrin | Rat | dorsomorphin | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NYNRIN mRNA | CTD | PMID:27188386 | Nynrin | Rat | doxorubicin | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of NYNRIN mRNA | CTD | PMID:29803840 | Nynrin | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of NYNRIN mRNA | CTD | PMID:33387578 | Nynrin | Rat | lipopolysaccharide | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with Resveratrol] results in increased expression of NYNRIN mRNA more ... | CTD | PMID:26667767 and PMID:35811015 | Nynrin | Rat | manganese atom | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of NYNRIN mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of NYNRIN mRNA | CTD | PMID:39836092 | Nynrin | Rat | manganese(0) | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of NYNRIN mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of NYNRIN mRNA | CTD | PMID:39836092 | Nynrin | Rat | manganese(II) chloride | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of NYNRIN mRNA and [manganese chloride results in increased abundance of Manganese] which results in decreased expression of NYNRIN mRNA | CTD | PMID:39836092 | Nynrin | Rat | methapyrilene | decreases methylation | ISO | NYNRIN (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of NYNRIN exon | CTD | PMID:30157460 | Nynrin | Rat | methylmercury chloride | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of NYNRIN mRNA | CTD | PMID:28001369 | Nynrin | Rat | nickel atom | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Nickel results in decreased expression of NYNRIN mRNA | CTD | PMID:24768652 and PMID:25583101 | Nynrin | Rat | ozone | multiple interactions | ISO | Nynrin (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of NYNRIN mRNA | CTD | PMID:34911549 | Nynrin | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NYNRIN mRNA | CTD | PMID:33387578 | Nynrin | Rat | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of NYNRIN mRNA | CTD | PMID:32680482 | Nynrin | Rat | phenylmercury acetate | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of NYNRIN mRNA | CTD | PMID:26272509 | Nynrin | Rat | phenylmercury acetate | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NYNRIN mRNA | CTD | PMID:27188386 | Nynrin | Rat | resveratrol | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with Resveratrol] results in increased expression of NYNRIN mRNA and [Plant Extracts co-treated with Resveratrol] results in decreased expression of NYNRIN mRNA | CTD | PMID:23557933 and PMID:26667767 | Nynrin | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of NYNRIN mRNA | CTD | PMID:35811015 | Nynrin | Rat | SB 431542 | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of NYNRIN mRNA | CTD | PMID:27188386 | Nynrin | Rat | silicon dioxide | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of NYNRIN mRNA | CTD | PMID:25895662 | Nynrin | Rat | sodium arsenate | decreases expression | ISO | Nynrin (Mus musculus) | 6480464 | sodium arsenate results in decreased expression of NYNRIN mRNA | CTD | PMID:21795629 | Nynrin | Rat | sodium arsenite | multiple interactions | ISO | NYNRIN (Homo sapiens) | 6480464 | [[sodium arsenite results in increased abundance of Arsenic] co-treated with [manganese chloride results in increased abundance of Manganese]] results in decreased expression of NYNRIN mRNA and [sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of NYNRIN mRNA | CTD | PMID:39836092 | Nynrin | Rat | sunitinib | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of NYNRIN mRNA | CTD | PMID:31533062 | Nynrin | Rat | thimerosal | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of NYNRIN mRNA | CTD | PMID:27188386 | Nynrin | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of NYNRIN mRNA | CTD | PMID:33387578 | Nynrin | Rat | tris(2-butoxyethyl) phosphate | affects expression | ISO | NYNRIN (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of NYNRIN mRNA | CTD | PMID:29024780 | Nynrin | Rat | valproic acid | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of NYNRIN mRNA | CTD | PMID:28001369 and PMID:29154799 | Nynrin | Rat | vorinostat | decreases expression | ISO | NYNRIN (Homo sapiens) | 6480464 | vorinostat results in decreased expression of NYNRIN mRNA | CTD | PMID:27188386 | |