Gene: Gzmb (granzyme B) Rattus norvegicus
Symbol: Gzmb
Name: granzyme B
Description: ENCODES a protein that exhibits serine-type endopeptidase activity; serine-type peptidase activity (ortholog); INVOLVED IN positive regulation of cell death; positive regulation of necroptotic process; granzyme-mediated apoptotic signaling pathway (ortholog); PARTICIPATES IN allograft rejection pathway; autoimmune thyroiditis pathway; graft-versus-host disease pathway; ASSOCIATED WITH Acute Lung Injury (ortholog); Autistic Disorder (ortholog); Breast Neoplasms (ortholog); FOUND IN early endosome; cytolytic granule (ortholog); cytoplasm (ortholog); INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 1-chloro-2,4-dinitrobenzene; 17beta-estradiol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: fragmentin; GLP I; GLP III; GLP-1; granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1); granzyme-like protein 1; granzyme-like protein I; LOW QUALITY PROTEIN: granzyme-like protein 1; MGC156565; natural killer cell protease 1; RNKP-1
Homo sapiens (human) : GZMB (granzyme B)  HGNC  Alliance
Mus musculus (house mouse) : Gzmb (granzyme B)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GZMB (granzyme B)
Canis lupus familiaris (dog) : GZMB (granzyme B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01535,413,862 - 35,417,293 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01539,296,950 - 39,300,381 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41535,195,075 - 35,198,506 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11535,211,149 - 35,214,166 (-)NCBI
Celera1529,891,059 - 29,893,786 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gzmb
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620018
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2018-03-20
Status: ACTIVE