Psme1 (proteasome activator subunit 1) - Rat Genome Database

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Gene: Psme1 (proteasome activator subunit 1) Rattus norvegicus
Analyze
Symbol: Psme1
Name: proteasome activator subunit 1
RGD ID: 3429
Description: Predicted to enable endopeptidase activator activity. Predicted to be involved in positive regulation of endopeptidase activity; regulation of G1/S transition of mitotic cell cycle; and regulation of proteasomal protein catabolic process. Predicted to act upstream of or within antigen processing and presentation of exogenous antigen. Predicted to be part of proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Orthologous to human PSME1 (proteasome activator subunit 1); PARTICIPATES IN antigen processing and presentation pathway; ubiquitin/proteasome degradation pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 11S regulator complex subunit alpha; activator of multicatalytic protease subunit 1; PA28a; PA28alpha; protease (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) 28 subunit, alpha; proteasome (prosome, macropain) activator subunit 1; proteasome activator 28 subunit alpha; proteasome activator complex subunit 1; REG-alpha
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Psme1-ps1  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21529,069,012 - 29,071,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,068,729 - 29,071,890 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,914,716 - 30,917,592 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01532,061,922 - 32,064,798 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01530,304,268 - 30,307,144 (+)NCBIRnor_WKY
Rnor_6.01534,256,071 - 34,258,947 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,256,071 - 34,258,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,146,266 - 38,149,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,712,892 - 33,715,769 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,728,591 - 33,731,469 (+)NCBI
Celera1528,644,934 - 28,647,810 (+)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
alendronic acid  (EXP)
all-trans-retinoic acid  (ISO)
alpha-hexachlorocyclohexane  (EXP)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP)
bromobenzene  (EXP)
cadmium dichloride  (EXP,ISO)
carbon nanotube  (ISO)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
decabromodiphenyl ether  (EXP,ISO)
dehydroepiandrosterone  (EXP)
diazinon  (EXP)
dibutyl phthalate  (EXP,ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
ethanol  (EXP)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
heparin  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lithium chloride  (ISO)
methidathion  (ISO)
methylmercury chloride  (ISO)
microcystin RR  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosomorpholine  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (EXP)
pirinixic acid  (ISO)
raloxifene  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP)
titanium dioxide  (ISO)
toluene  (EXP)
Tributyltin oxide  (ISO)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Primary structures of two homologous subunits of PA28, a gamma-interferon-inducible protein activator of the 20S proteasome. Ahn JY, etal., FEBS Lett 1995 Jun 5;366(1):37-42.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9679960   PMID:12477932   PMID:15944286   PMID:19182904   PMID:20458337   PMID:21098724   PMID:23376485  


Genomics

Comparative Map Data
Psme1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21529,069,012 - 29,071,888 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1529,068,729 - 29,071,890 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1530,914,716 - 30,917,592 (+)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01532,061,922 - 32,064,798 (+)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01530,304,268 - 30,307,144 (+)NCBIRnor_WKY
Rnor_6.01534,256,071 - 34,258,947 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,256,071 - 34,258,947 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,146,266 - 38,149,142 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,712,892 - 33,715,769 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11533,728,591 - 33,731,469 (+)NCBI
Celera1528,644,934 - 28,647,810 (+)NCBICelera
Cytogenetic Map15p13NCBI
PSME1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381424,136,194 - 24,138,962 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1424,136,163 - 24,138,967 (+)EnsemblGRCh38hg38GRCh38
GRCh371424,605,403 - 24,608,171 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361423,675,218 - 23,678,016 (+)NCBINCBI36Build 36hg18NCBI36
Build 341423,675,217 - 23,678,015NCBI
Celera144,469,848 - 4,472,646 (+)NCBICelera
Cytogenetic Map14q12NCBI
HuRef144,720,599 - 4,723,242 (+)NCBIHuRef
CHM1_11424,604,038 - 24,606,847 (+)NCBICHM1_1
T2T-CHM13v2.01418,334,505 - 18,337,273 (+)NCBIT2T-CHM13v2.0
Psme1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391455,815,951 - 55,818,984 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1455,815,580 - 55,818,986 (+)EnsemblGRCm39 Ensembl
GRCm381455,578,494 - 55,581,527 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1455,578,123 - 55,581,529 (+)EnsemblGRCm38mm10GRCm38
MGSCv371456,197,331 - 56,200,364 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361454,532,565 - 54,535,598 (+)NCBIMGSCv36mm8
Celera1453,383,350 - 53,386,383 (+)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1428.19NCBI
Psme1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540936,262,114 - 36,264,994 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540936,262,114 - 36,264,996 (-)NCBIChiLan1.0ChiLan1.0
PSME1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11423,036,223 - 23,039,405 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1423,033,548 - 23,039,405 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0144,912,390 - 4,915,219 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PSME1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.184,131,197 - 4,134,001 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl84,131,345 - 4,134,006 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha84,052,885 - 4,055,693 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.084,241,777 - 4,244,585 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl84,241,348 - 4,244,585 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.183,932,403 - 3,935,211 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.083,994,149 - 3,996,957 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.084,256,309 - 4,259,117 (+)NCBIUU_Cfam_GSD_1.0
Psme1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864035,980,669 - 35,983,504 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936722405,491 - 408,277 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PSME1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl775,160,766 - 75,164,810 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1775,161,830 - 75,164,531 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2780,433,126 - 80,435,826 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap7q12-q23NCBI
PSME1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1241,122,086 - 1,124,907 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl241,122,631 - 1,125,416 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603612,803,781 - 12,806,636 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Psme1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248208,397,344 - 8,400,285 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248208,397,344 - 8,400,273 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Position Markers
Psme1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21529,070,638 - 29,071,171 (+)MAPPERmRatBN7.2
Rnor_6.01534,257,698 - 34,258,230NCBIRnor6.0
Rnor_5.01538,147,893 - 38,148,425UniSTSRnor5.0
RGSC_v3.41533,714,520 - 33,715,052UniSTSRGSC3.4
Celera1528,646,561 - 28,647,093UniSTS
Cytogenetic Map15p13UniSTS
AW413925  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21529,071,740 - 29,071,873 (+)MAPPERmRatBN7.2
Rnor_6.01534,258,800 - 34,258,932NCBIRnor6.0
Rnor_5.01538,148,995 - 38,149,127UniSTSRnor5.0
RGSC_v3.41533,715,622 - 33,715,754UniSTSRGSC3.4
Celera1528,647,663 - 28,647,795UniSTS
Cytogenetic Map15p13UniSTS
UniSTS:237187  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21529,071,885 - 29,072,091 (+)MAPPERmRatBN7.2
Rnor_6.01534,258,945 - 34,259,150NCBIRnor6.0
Rnor_5.01538,149,140 - 38,149,345UniSTSRnor5.0
RGSC_v3.41533,715,767 - 33,715,972UniSTSRGSC3.4
Celera1528,647,808 - 28,648,013UniSTS
Cytogenetic Map15p13UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:25
Count of miRNA genes:25
Interacting mature miRNAs:25
Transcripts:ENSRNOT00000025887
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 54 39 19 39 2 63 28 35 11
Low 3 2 2 8 9 11 7 6 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000025887   ⟹   ENSRNOP00000025887
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1529,068,729 - 29,071,890 (+)Ensembl
Rnor_6.0 Ensembl1534,256,071 - 34,258,947 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098373   ⟹   ENSRNOP00000086094
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1529,069,034 - 29,071,890 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000101716   ⟹   ENSRNOP00000080362
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1529,068,729 - 29,071,890 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000111999   ⟹   ENSRNOP00000096823
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1529,069,065 - 29,071,872 (+)Ensembl
RefSeq Acc Id: NM_017264   ⟹   NP_058960
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21529,069,012 - 29,071,888 (+)NCBI
Rnor_6.01534,256,071 - 34,258,947 (+)NCBI
Rnor_5.01538,146,266 - 38,149,142 (+)NCBI
RGSC_v3.41533,712,892 - 33,715,769 (+)RGD
Celera1528,644,934 - 28,647,810 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058960 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH60574 (Get FASTA)   NCBI Sequence Viewer  
  BAA08206 (Get FASTA)   NCBI Sequence Viewer  
  EDM14241 (Get FASTA)   NCBI Sequence Viewer  
  Q63797 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058960   ⟸   NM_017264
- UniProtKB: Q6P9V7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000025887   ⟸   ENSRNOT00000025887
RefSeq Acc Id: ENSRNOP00000080362   ⟸   ENSRNOT00000101716
RefSeq Acc Id: ENSRNOP00000086094   ⟸   ENSRNOT00000098373
RefSeq Acc Id: ENSRNOP00000096823   ⟸   ENSRNOT00000111999
Protein Domains
PA28_alpha   PA28_beta

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63797-F1-model_v2 AlphaFold Q63797 1-249 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699672
Promoter ID:EPDNEW_R10195
Type:initiation region
Name:Psme1_1
Description:proteasome activator subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01534,256,122 - 34,256,182EPDNEW

Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3429 AgrOrtholog
BioCyc Gene G2FUF-13712 BioCyc
Ensembl Genes ENSRNOG00000019041 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000025887 ENTREZGENE
  ENSRNOP00000025887.3 UniProtKB/TrEMBL
  ENSRNOP00000080362.1 UniProtKB/TrEMBL
  ENSRNOP00000086094.1 UniProtKB/TrEMBL
  ENSRNOP00000096823.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000025887 ENTREZGENE
  ENSRNOT00000025887.6 UniProtKB/TrEMBL
  ENSRNOT00000098373.1 UniProtKB/TrEMBL
  ENSRNOT00000101716.1 UniProtKB/TrEMBL
  ENSRNOT00000111999.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.120.180 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.20.5.120 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6890794 IMAGE-MGC_LOAD
InterPro PA28_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA28_C_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA28_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proteasome_activ_PA28 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proteasome_activ_PA28_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proteasome_activ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29630 UniProtKB/TrEMBL
MGC_CLONE MGC:72874 IMAGE-MGC_LOAD
NCBI Gene 29630 ENTREZGENE
PANTHER PTHR10660 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PA28_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PA28_beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Psme1 PhenoGen
Superfamily-SCOP SSF47216 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZQ53_RAT UniProtKB/TrEMBL
  A0A8I6A5D1_RAT UniProtKB/TrEMBL
  A0A8I6AU10_RAT UniProtKB/TrEMBL
  PSME1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6P9V7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-05-11 Psme1  proteasome activator subunit 1  Psme1  proteasome (prosome, macropain) activator subunit 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-12-15 Psme1  proteasome (prosome, macropain) activator subunit 1  Psme1  proteasome (prosome, macropain) 28 subunit, alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Psme1  proteasome (prosome, macropain) 28 subunit, alpha    protease (prosome, macropain) 28 subunit, alpha  Name updated 1299863 APPROVED
2002-06-10 Psme1  protease (prosome, macropain) 28 subunit, alpha      Name updated 70584 APPROVED