Ttc5 (tetratricopeptide repeat domain 5) - Rat Genome Database

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Gene: Ttc5 (tetratricopeptide repeat domain 5) Rattus norvegicus
Analyze
Symbol: Ttc5
Name: tetratricopeptide repeat domain 5
RGD ID: 1311284
Description: Predicted to enable DNA binding activity; chromatin binding activity; and ribosome binding activity. Predicted to be involved in DNA damage response; cellular response to starvation; and positive regulation of mRNA catabolic process. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including cytosol; mitochondrion; and nucleoplasm. Orthologous to human TTC5 (tetratricopeptide repeat domain 5); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC305837; MGC108914; strap; stress-responsive activator of p300; tetratricopeptide repeat protein 5; TPR repeat protein 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,466,613 - 26,484,269 (-)NCBIGRCr8
mRatBN7.21523,993,046 - 24,010,710 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1523,993,048 - 24,010,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1526,764,272 - 26,781,856 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,722,902 - 27,740,465 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01525,972,796 - 25,990,392 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,698,375 - 27,715,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,698,362 - 27,716,008 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,530,800 - 31,548,395 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41526,749,259 - 26,766,848 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,764,960 - 26,782,548 (-)NCBI
Celera1524,312,000 - 24,330,147 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc5RatNEURODEVELOPMENTAL DISORDER WITH CEREBRAL ATROPHY AND VARIABLE FACIAL DYSMORPHISM  ISOTTC5 (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorder with cerebral atrophy and variable facial dysmorphismClinVarPMID:25741868 more ...
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc5RatNEURODEVELOPMENTAL DISORDER WITH CEREBRAL ATROPHY AND VARIABLE FACIAL DYSMORPHISM  ISOTTC5 (Homo sapiens)7240710 OMIM 

1 to 20 of 34 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc5Rat1,2-dimethylhydrazine multiple interactionsISOTtc5 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TTC5 mRNACTDPMID:22206623
Ttc5Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of TTC5 mRNACTDPMID:33387578
Ttc5Rat2-palmitoylglycerol increases expressionISOTTC5 (Homo sapiens)64804642-palmitoylglycerol results in increased expression of TTC5 mRNACTDPMID:37199045
Ttc5Rat4,4'-diaminodiphenylmethane increases expressionISOTtc5 (Mus musculus)64804644 and 4'-diaminodiphenylmethane results in increased expression of TTC5 mRNACTDPMID:18648102
Ttc5Rat4,4'-sulfonyldiphenol decreases expressionISOTtc5 (Mus musculus)6480464bisphenol S results in decreased expression of TTC5 mRNACTDPMID:39298647
Ttc5Rataflatoxin B1 decreases methylationISOTTC5 (Homo sapiens)6480464Aflatoxin B1 results in decreased methylation of TTC5 geneCTDPMID:27153756
Ttc5Rataristolochic acid A decreases expressionISOTTC5 (Homo sapiens)6480464aristolochic acid I results in decreased expression of TTC5 mRNACTDPMID:33212167
Ttc5Ratbenzo[a]pyrene increases expressionISOTtc5 (Mus musculus)6480464Benzo(a)pyrene results in increased expression of TTC5 mRNACTDPMID:22228805
Ttc5Ratbenzo[a]pyrene decreases methylationISOTTC5 (Homo sapiens)6480464Benzo(a)pyrene results in decreased methylation of TTC5 promoterCTDPMID:27901495
Ttc5Ratbenzo[a]pyrene multiple interactionsISOTtc5 (Mus musculus)6480464AHR protein affects the reaction [Benzo(a)pyrene affects the expression of TTC5 mRNA]CTDPMID:22228805
Ttc5Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of TTC5 mRNACTDPMID:25181051
Ttc5Ratcarbon nanotube decreases expressionISOTtc5 (Mus musculus)6480464Nanotubes more ...CTDPMID:25554681
Ttc5RatCGP 52608 multiple interactionsISOTTC5 (Homo sapiens)6480464CGP 52608 promotes the reaction [RORA protein binds to TTC5 gene]CTDPMID:28238834
Ttc5Ratcopper(II) sulfate decreases expressionISOTTC5 (Homo sapiens)6480464Copper Sulfate results in decreased expression of TTC5 mRNACTDPMID:19549813
Ttc5Ratdioxygen decreases expressionISOTtc5 (Mus musculus)6480464Oxygen deficiency results in decreased expression of TTC5 mRNACTDPMID:24205000
Ttc5Ratdorsomorphin multiple interactionsISOTTC5 (Homo sapiens)6480464[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TTC5 mRNACTDPMID:27188386
Ttc5Ratfolic acid decreases expressionISOTtc5 (Mus musculus)6480464Folic Acid results in decreased expression of TTC5 mRNACTDPMID:25629700
Ttc5Ratfolic acid multiple interactionsISOTtc5 (Mus musculus)6480464[1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of TTC5 mRNACTDPMID:22206623
Ttc5Ratgentamycin decreases expressionEXP 6480464Gentamicins results in decreased expression of TTC5 mRNACTDPMID:33387578
Ttc5Ratmethimazole increases expressionEXP 6480464Methimazole results in increased expression of TTC5 mRNACTDPMID:38685447

1 to 20 of 34 rows

Biological Process
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc5Ratcellular response to starvation involved_inISSUniProtKB:Q99LG41600115GO_REF:0000024UniProtGO_REF:0000024
Ttc5Ratcellular response to starvation involved_inIEAUniProtKB:Q99LG4 and ensembl:ENSMUSP000000064511600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratcellular response to starvation involved_inISOTtc5 (Mus musculus)1624291 PMID:30420355RGDPMID:30420355
Ttc5RatDNA damage response involved_inISOTtc5 (Mus musculus)1624291 PMID:15448695 and PMID:18833288RGDPMID:15448695 and PMID:18833288
Ttc5RatDNA damage response involved_inIEAUniProtKB:Q99LG4 and ensembl:ENSMUSP000000064511600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5RatDNA damage response involved_inIEAUniProtKB-KW:KW-02271600115GO_REF:0000043UniProtGO_REF:0000043
Ttc5RatDNA damage response involved_inISSUniProtKB:Q99LG41600115GO_REF:0000024UniProtGO_REF:0000024
Ttc5RatDNA repair involved_inIEAUniProtKB-KW:KW-02341600115GO_REF:0000043UniProtGO_REF:0000043
Ttc5Ratpositive regulation of mRNA catabolic process involved_inISOTTC5 (Homo sapiens)1624291 PMID:31727855RGDPMID:31727855
Ttc5Ratpositive regulation of mRNA catabolic process involved_inIEAUniProtKB:Q8N0Z6 and ensembl:ENSP000002588211600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratpositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinIEAUniProtKB:Q99LG4 and ensembl:ENSMUSP000000064511600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratpositive regulation of transcription by RNA polymerase II acts_upstream_of_or_withinISOTtc5 (Mus musculus)1624291MGI:98834 PMID:22362889RGDPMID:22362889
1 to 12 of 12 rows

Cellular Component
1 to 20 of 26 rows

  
Object Symbol
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Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc5Ratcytoplasm located_inIEAUniProtKB:Q99LG4 and ensembl:ENSMUSP000000064511600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Ttc5Ratcytoplasm located_inIEAUniProtKB-SubCell:SL-00861600115GO_REF:0000044UniProtGO_REF:0000044
Ttc5Ratcytoplasm located_inISOTtc5 (Mus musculus)1624291 PMID:22362889RGDPMID:22362889
Ttc5Ratcytoplasmic vesicle located_inIEAUniProtKB-KW:KW-09681600115GO_REF:0000043UniProtGO_REF:0000043
Ttc5Ratcytoplasmic vesicle located_inIEAUniProtKB:Q99LG4 and ensembl:ENSMUSP000000064511600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratcytoplasmic vesicle located_inISOTtc5 (Mus musculus)1624291 PMID:30420355RGDPMID:30420355
Ttc5Ratcytoplasmic vesicle located_inISSUniProtKB:Q99LG41600115GO_REF:0000024UniProtGO_REF:0000024
Ttc5Ratcytosol located_inISOTtc5 (Mus musculus)1624291 PMID:15448695 more ...RGDPMID:15448695 more ...
Ttc5Ratcytosol located_inIEAUniProtKB:Q8N0Z6 and ensembl:ENSP000002588211600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratcytosol located_inIEAUniProtKB:Q99LG4 and ensembl:ENSMUSP000000064511600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratcytosol located_inISOTTC5 (Homo sapiens)1624291 PMID:31727855RGDPMID:31727855
Ttc5Ratcytosol located_inISSUniProtKB:Q8N0Z61600115GO_REF:0000024UniProtGO_REF:0000024
Ttc5Ratcytosol located_inISSUniProtKB:Q99LG41600115GO_REF:0000024UniProtGO_REF:0000024
Ttc5Ratmitochondrial matrix located_inIEAUniProtKB-SubCell:SL-01701600115GO_REF:0000044UniProtGO_REF:0000044
Ttc5Ratmitochondrion located_inIEAUniProtKB-KW:KW-04961600115GO_REF:0000043UniProtGO_REF:0000043
Ttc5Ratmitochondrion located_inISOTtc5 (Mus musculus)1624291 PMID:25168243RGDPMID:25168243
Ttc5Ratmitochondrion located_inISSUniProtKB:Q99LG41600115GO_REF:0000024UniProtGO_REF:0000024
Ttc5Ratmitochondrion located_inIEAUniProtKB:Q99LG4 and ensembl:ENSMUSP000000064511600115GO_REF:0000107EnsemblGO_REF:0000107
Ttc5Ratnucleoplasm located_inIEAUniProtKB:Q8N0Z6 and ensembl:ENSP000002588211600115GO_REF:0000107EnsemblGO_REF:0000107
1 to 20 of 26 rows

Molecular Function

  

Imported Annotations - PID (archival)

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ttc5Ratp53 signaling pathway   ISOTTC5 (Homo sapiens)6484113 PIDPID:200206

#
Reference Title
Reference Citation
1. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:15489334   PMID:22362889  



Ttc5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81526,466,613 - 26,484,269 (-)NCBIGRCr8
mRatBN7.21523,993,046 - 24,010,710 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1523,993,048 - 24,010,668 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1526,764,272 - 26,781,856 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01527,722,902 - 27,740,465 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01525,972,796 - 25,990,392 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01527,698,375 - 27,715,970 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1527,698,362 - 27,716,008 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01531,530,800 - 31,548,395 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41526,749,259 - 26,766,848 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11526,764,960 - 26,782,548 (-)NCBI
Celera1524,312,000 - 24,330,147 (-)NCBICelera
Cytogenetic Map15p14NCBI
TTC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381420,286,227 - 20,305,951 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1420,256,558 - 20,305,960 (-)EnsemblGRCh38hg38GRCh38
GRCh371420,754,386 - 20,774,110 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361419,827,144 - 19,843,976 (-)NCBINCBI36Build 36hg18NCBI36
Build 341419,827,143 - 19,843,976NCBI
Celera14618,437 - 635,301 (-)NCBICelera
Cytogenetic Map14q11.2NCBI
HuRef14879,432 - 896,309 (-)NCBIHuRef
CHM1_11420,758,235 - 20,775,107 (-)NCBICHM1_1
T2T-CHM13v2.01414,483,002 - 14,502,708 (-)NCBIT2T-CHM13v2.0
Ttc5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391451,002,866 - 51,022,977 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1451,002,872 - 51,022,976 (-)EnsemblGRCm39 Ensembl
GRCm381450,765,409 - 50,785,520 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1450,765,415 - 50,785,519 (-)EnsemblGRCm38mm10GRCm38
MGSCv371451,385,090 - 51,405,193 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361449,697,406 - 49,707,446 (-)NCBIMGSCv36mm8
Celera1447,053,176 - 47,073,234 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1426.24NCBI
Ttc5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,074,170 - 1,105,357 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,073,697 - 1,105,055 (-)NCBIChiLan1.0ChiLan1.0
TTC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21521,795,330 - 21,815,184 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11421,011,312 - 21,031,670 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0141,163,280 - 1,180,212 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11419,214,337 - 19,233,797 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,216,993 - 19,233,797 (-)Ensemblpanpan1.1panPan2
TTC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11517,653,008 - 17,670,231 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1517,638,462 - 17,670,575 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,137,305 - 18,155,363 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01517,910,664 - 17,929,053 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1517,910,691 - 17,929,008 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11517,594,498 - 17,612,265 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01517,648,692 - 17,666,694 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01517,777,371 - 17,795,817 (-)NCBIUU_Cfam_GSD_1.0
Ttc5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864077,515,241 - 77,539,652 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936877501,743 - 520,316 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936877504,406 - 520,295 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,578,294 - 78,600,592 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,578,247 - 78,600,794 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2783,606,604 - 83,626,652 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TTC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12920,809,004 - 20,825,918 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2920,808,945 - 20,826,111 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605925,595,832 - 25,612,685 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttc5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248254,863,028 - 4,900,363 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248254,863,610 - 4,923,164 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Ttc5
36 total Variants

Predicted Target Of
Summary Value
Count of predictions:294
Count of miRNA genes:172
Interacting mature miRNAs:211
Transcripts:ENSRNOT00000011741
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 25 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat

1 to 10 of 25 rows
RH127591  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21523,993,294 - 23,993,478 (+)MAPPERmRatBN7.2
Rnor_6.01527,698,615 - 27,698,798NCBIRnor6.0
Rnor_5.01531,531,040 - 31,531,223UniSTSRnor5.0
RGSC_v3.41526,749,499 - 26,749,682UniSTSRGSC3.4
Celera1524,312,240 - 24,312,423UniSTS
Cytogenetic Map15p14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000011741   ⟹   ENSRNOP00000011741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1523,993,048 - 24,010,668 (-)Ensembl
Rnor_6.0 Ensembl1527,698,362 - 27,716,008 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000118299   ⟹   ENSRNOP00000090197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1523,993,048 - 24,007,641 (-)Ensembl
RefSeq Acc Id: NM_001013131   ⟹   NP_001013149
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,466,617 - 26,484,212 (-)NCBI
mRatBN7.21523,993,055 - 24,010,655 (-)NCBI
Rnor_6.01527,698,375 - 27,715,970 (-)NCBI
Rnor_5.01531,530,800 - 31,548,395 (-)NCBI
RGSC_v3.41526,749,259 - 26,766,848 (-)RGD
Celera1524,312,000 - 24,330,147 (-)RGD
Sequence:
RefSeq Acc Id: XM_039093271   ⟹   XP_038949199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,474,061 - 26,484,269 (-)NCBI
mRatBN7.21524,000,570 - 24,010,710 (-)NCBI
RefSeq Acc Id: XM_063274219   ⟹   XP_063130289
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,466,613 - 26,476,734 (-)NCBI
RefSeq Acc Id: XR_010057812
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81526,471,811 - 26,484,269 (-)NCBI
Protein RefSeqs NP_001013149 (Get FASTA)   NCBI Sequence Viewer  
  XP_038949199 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130289 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91207 (Get FASTA)   NCBI Sequence Viewer  
  EDL88410 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011741
  ENSRNOP00000011741.5
GenBank Protein Q5BK48 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001013149   ⟸   NM_001013131
- UniProtKB: Q5BK48 (UniProtKB/Swiss-Prot),   A6KEA5 (UniProtKB/TrEMBL),   A0A8I6GIP6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000011741   ⟸   ENSRNOT00000011741
RefSeq Acc Id: XP_038949199   ⟸   XM_039093271
- Peptide Label: isoform X2
Ensembl Acc Id: ENSRNOP00000090197   ⟸   ENSRNOT00000118299
RefSeq Acc Id: XP_063130289   ⟸   XM_063274219
- Peptide Label: isoform X1
Tetratricopeptide repeat protein 5 OB fold

Name Modeler Protein Id AA Range Protein Structure
AF-Q5BK48-F1-model_v2 AlphaFold Q5BK48 1-440 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13699619
Promoter ID:EPDNEW_R10143
Type:multiple initiation site
Name:Ttc5_1
Description:tetratricopeptide repeat domain 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01527,715,973 - 27,716,033EPDNEW


1 to 27 of 27 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14065 BioCyc
Ensembl Genes ENSRNOG00000008850 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000011741 ENTREZGENE
  ENSRNOT00000011741.8 UniProtKB/Swiss-Prot
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot
  2.40.50.550 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7381272 IMAGE-MGC_LOAD
InterPro TPR-like_helical_dom_sf UniProtKB/Swiss-Prot
  TPR_repeat UniProtKB/Swiss-Prot
  TTC5_OB UniProtKB/Swiss-Prot
  TTC5_OB_sf UniProtKB/Swiss-Prot
  Ycf3/AcsC/BcsC/TPR_MFPF UniProtKB/Swiss-Prot
KEGG Report rno:305837 UniProtKB/Swiss-Prot
MGC_CLONE MGC:108914 IMAGE-MGC_LOAD
NCBI Gene 305837 ENTREZGENE
PANTHER CELLULOSE SYNTHASE OPERON PROTEIN C UniProtKB/Swiss-Prot
  TPR REPEAT-CONTAINING PROTEIN MJ0798 UniProtKB/Swiss-Prot
Pfam TTC5_OB UniProtKB/Swiss-Prot
PhenoGen Ttc5 PhenoGen
PROSITE TPR UniProtKB/Swiss-Prot
  TPR_REGION UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000008850 RatGTEx
SMART TPR UniProtKB/Swiss-Prot
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot
UniProt A0A8I6GIP6 ENTREZGENE, UniProtKB/TrEMBL
  A6KEA5 ENTREZGENE, UniProtKB/TrEMBL
  Q5BK48 ENTREZGENE, UniProtKB/Swiss-Prot
1 to 27 of 27 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Ttc5  tetratricopeptide repeat domain 5  Ttc5_predicted  tetratricopeptide repeat domain 5 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Ttc5_predicted  tetratricopeptide repeat domain 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED