Gmfb (glia maturation factor, beta) - Rat Genome Database

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Gene: Gmfb (glia maturation factor, beta) Rattus norvegicus
Analyze
Symbol: Gmfb
Name: glia maturation factor, beta
RGD ID: 70910
Description: Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within learning and locomotory behavior. Predicted to be active in cortical actin cytoskeleton. Orthologous to human GMFB (glia maturation factor beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DNA for thyroid hormone receptor binding site (276bp); glia maturation factor beta; GMF-beta; MGC93372
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81522,549,705 - 22,560,125 (-)NCBIGRCr8
mRatBN7.21520,069,923 - 20,081,005 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1520,067,263 - 20,080,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1522,850,667 - 22,860,918 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01523,808,661 - 23,818,912 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01522,058,939 - 22,069,311 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01523,597,846 - 23,611,541 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1523,601,368 - 23,606,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01527,541,333 - 27,555,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41522,664,728 - 22,675,100 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11522,680,429 - 22,690,800 (-)NCBI
Celera1520,468,408 - 20,478,698 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GmfbRatDOPA-responsive dystonia  ISOGMFB (Homo sapiens)8554872ClinVar Annotator: match by term: Dystonia 5ClinVarPMID:17111153 more ...
GmfbRatsyndromic microphthalmia 6  ISOGMFB (Homo sapiens)8554872ClinVar Annotator: match by term: Microphthalmia with brain and digit anomaliesClinVarPMID:18252212 more ...

1 to 20 of 104 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GmfbRat(-)-demecolcine increases expressionISOGMFB (Homo sapiens)6480464Demecolcine results in increased expression of GMFB mRNACTDPMID:23649840
GmfbRat(1->4)-beta-D-glucan multiple interactionsISOGmfb (Mus musculus)6480464[perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GMFB mRNACTDPMID:36331819
GmfbRat(S)-nicotine multiple interactionsISOGmfb (Mus musculus)6480464[Nicotine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
GmfbRat1,2-dimethylhydrazine multiple interactionsISOGmfb (Mus musculus)6480464Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of GMFB mRNA]CTDPMID:22206623
GmfbRat1,2-dimethylhydrazine decreases expressionISOGmfb (Mus musculus)64804641 and 2-Dimethylhydrazine results in decreased expression of GMFB mRNACTDPMID:22206623
GmfbRat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expressionISOGmfb (Mus musculus)64804641-Methyl-4-phenyl-1 more ...CTDPMID:20230807
GmfbRat1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactionsISOGmfb (Mus musculus)6480464[Caffeine co-treated with 1-Methyl-4-phenyl-1 more ...CTDPMID:20230807
GmfbRat17beta-estradiol decreases expressionISOGmfb (Mus musculus)6480464Estradiol results in decreased expression of GMFB mRNACTDPMID:39298647
GmfbRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGMFB (Homo sapiens)6480464Tetrachlorodibenzodioxin results in increased expression of GMFB mRNACTDPMID:21632981
GmfbRat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of GMFB mRNACTDPMID:33387578
GmfbRat2,3,7,8-tetrachlorodibenzodioxine increases expressionISOGmfb (Mus musculus)6480464Tetrachlorodibenzodioxin results in increased expression of GMFB mRNACTDPMID:15034205 and PMID:17942748
GmfbRat2,3,7,8-tetrachlorodibenzodioxine multiple interactionsISOGmfb (Mus musculus)6480464AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GMFB mRNA]CTDPMID:15034205
GmfbRat2,4-dinitrotoluene affects expressionEXP 64804642 and 4-dinitrotoluene affects the expression of GMFB mRNACTDPMID:21346803
GmfbRat2,6-dinitrotoluene affects expressionEXP 64804642 and 6-dinitrotoluene affects the expression of GMFB mRNACTDPMID:21346803
GmfbRat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of GMFB mRNACTDPMID:30047161
GmfbRatacetamide decreases expressionEXP 6480464acetamide results in decreased expression of GMFB mRNACTDPMID:31881176
GmfbRataflatoxin M1 decreases expressionISOGMFB (Homo sapiens)6480464Aflatoxin M1 results in decreased expression of GMFB mRNACTDPMID:30928695
GmfbRatalpha-Zearalanol multiple interactionsEXP 6480464[Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of GMFB mRNACTDPMID:35163327
GmfbRatamitrole increases expressionEXP 6480464Amitrole results in increased expression of GMFB mRNACTDPMID:30047161
GmfbRatatrazine decreases expressionISOGMFB (Homo sapiens)6480464Atrazine results in decreased expression of GMFB mRNACTDPMID:22378314

1 to 20 of 104 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GmfbRatactin filament debranching involved_inIEAInterPro:IPR0111711600115GO_REF:0000002InterProGO_REF:0000002
GmfbRatactin filament debranching involved_inIBAFB:FBgn0028894 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
GmfbRatlearning acts_upstream_of_or_withinISOGmfb (Mus musculus)1624291MGI:3056591 PMID:15451385RGDPMID:15451385
GmfbRatlocomotory behavior acts_upstream_of_or_withinISOGmfb (Mus musculus)1624291MGI:3056591 PMID:15451385RGDPMID:15451385
GmfbRatnegative regulation of Arp2/3 complex-mediated actin nucleation involved_inIBAFB:FBgn0028894 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
GmfbRatsignal transduction involved_inIEAGO:00080831600115GO_REF:0000108GOCGO_REF:0000108

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GmfbRatcortical actin cytoskeleton is_active_inIBAPANTHER:PTN000882413 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
GmfbRatactin binding enablesIEAInterPro:IPR0021081600115GO_REF:0000002InterProGO_REF:0000002
GmfbRatArp2/3 complex binding enablesIEAInterPro:IPR0111711600115GO_REF:0000002InterProGO_REF:0000002
GmfbRatArp2/3 complex binding enablesIBAPANTHER:PTN000882413 and PomBase:SPAC17H9.111600115GO_REF:0000033GO_CentralGO_REF:0000033
GmfbRatgrowth factor activity enablesIEAUniRule:UR0011167791600115GO_REF:0000104UniProtGO_REF:0000104
GmfbRatgrowth factor activity enablesIEAUniProtKB-KW:KW-03391600115GO_REF:0000043UniProtGO_REF:0000043


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Gene Data Set MGD Curation, June 12, 2002
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Expression of glia maturation factor beta mRNA and protein in rat organs and cells. Zaheer A, etal., J Neurochem 1993 Mar;60(3):914-20.
PMID:12477932   PMID:15451385   PMID:15489334   PMID:29476059   PMID:30191459   PMID:31505169   PMID:37121966   PMID:37904673  



Gmfb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81522,549,705 - 22,560,125 (-)NCBIGRCr8
mRatBN7.21520,069,923 - 20,081,005 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1520,067,263 - 20,080,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1522,850,667 - 22,860,918 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01523,808,661 - 23,818,912 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01522,058,939 - 22,069,311 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01523,597,846 - 23,611,541 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1523,601,368 - 23,606,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01527,541,333 - 27,555,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41522,664,728 - 22,675,100 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11522,680,429 - 22,690,800 (-)NCBI
Celera1520,468,408 - 20,478,698 (-)NCBICelera
Cytogenetic Map15p14NCBI
GMFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381454,474,485 - 54,488,980 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1454,474,484 - 54,489,025 (-)EnsemblGRCh38hg38GRCh38
GRCh371454,941,203 - 54,955,698 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361454,010,959 - 54,025,494 (-)NCBINCBI36Build 36hg18NCBI36
Build 341454,010,958 - 54,025,494NCBI
Celera1434,990,739 - 35,005,274 (-)NCBICelera
Cytogenetic Map14q22.2NCBI
HuRef1435,103,853 - 35,118,388 (-)NCBIHuRef
CHM1_11454,879,910 - 54,894,446 (-)NCBICHM1_1
T2T-CHM13v2.01448,679,656 - 48,694,147 (-)NCBIT2T-CHM13v2.0
Gmfb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391447,045,606 - 47,059,711 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1447,045,606 - 47,059,699 (-)EnsemblGRCm39 Ensembl
GRCm381446,808,149 - 46,822,259 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1446,808,149 - 46,822,242 (-)EnsemblGRCm38mm10GRCm38
MGSCv371447,427,824 - 47,441,917 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361445,730,026 - 45,744,086 (-)NCBIMGSCv36mm8
Celera1442,976,366 - 42,990,224 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1424.32NCBI
Gmfb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554098,969,398 - 8,984,257 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554098,969,398 - 8,984,008 (+)NCBIChiLan1.0ChiLan1.0
GMFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21555,596,106 - 55,610,916 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11454,812,615 - 54,827,432 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01435,061,469 - 35,076,234 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11453,339,536 - 53,353,873 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1453,343,142 - 53,348,840 (-)Ensemblpanpan1.1panPan2
GMFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1830,394,020 - 30,408,408 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl830,359,499 - 30,408,357 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha830,162,606 - 30,177,006 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0830,651,153 - 30,665,519 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl830,651,155 - 30,665,487 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1830,255,325 - 30,269,686 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0830,331,779 - 30,346,147 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0830,697,308 - 30,711,696 (-)NCBIUU_Cfam_GSD_1.0
Gmfb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864074,839,349 - 74,853,751 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936697613,547 - 625,438 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936697613,535 - 627,906 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1183,846,680 - 183,863,398 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11183,846,672 - 183,863,396 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GMFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12431,643,202 - 31,655,819 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2431,640,022 - 31,655,768 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605319,872,348 - 19,887,054 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gmfb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473114,790,384 - 14,804,163 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473114,790,338 - 14,804,163 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

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Variants in Gmfb
56 total Variants

Predicted Target Of
Summary Value
Count of predictions:803
Count of miRNA genes:322
Interacting mature miRNAs:428
Transcripts:ENSRNOT00000075602
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 21 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat

1 to 10 of 21 rows
RH132322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21520,067,440 - 20,067,634 (+)MAPPERmRatBN7.2
Rnor_6.01523,598,031 - 23,598,224NCBIRnor6.0
Rnor_5.01527,541,518 - 27,541,711UniSTSRnor5.0
RGSC_v3.41522,662,241 - 22,662,434UniSTSRGSC3.4
Celera1520,465,921 - 20,466,114UniSTS
RH 3.4 Map15186.3UniSTS
Cytogenetic Map15p14UniSTS
BE095473  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21520,080,436 - 20,080,602 (+)MAPPERmRatBN7.2
Rnor_6.01523,611,027 - 23,611,192NCBIRnor6.0
Rnor_5.01527,554,514 - 27,554,679UniSTSRnor5.0
RGSC_v3.41522,675,237 - 22,675,402UniSTSRGSC3.4
Celera1520,478,835 - 20,479,000UniSTS
RH 3.4 Map15189.0UniSTS
Cytogenetic Map15p14UniSTS
Gmfb  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21520,069,957 - 20,070,671 (+)MAPPERmRatBN7.2
Rnor_6.01523,600,548 - 23,601,261NCBIRnor6.0
Rnor_5.01527,544,035 - 27,544,748UniSTSRnor5.0
Celera1520,468,438 - 20,469,151UniSTS
Cytogenetic Map15p14UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000075602   ⟹   ENSRNOP00000067695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1520,070,778 - 20,076,045 (-)Ensembl
Rnor_6.0 Ensembl1523,601,368 - 23,606,634 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101993   ⟹   ENSRNOP00000089942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1520,067,263 - 20,080,331 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119616   ⟹   ENSRNOP00000083410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1520,067,263 - 20,076,414 (-)Ensembl
RefSeq Acc Id: NM_031032   ⟹   NP_112294
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81522,549,705 - 22,560,077 (-)NCBI
mRatBN7.21520,069,928 - 20,080,300 (-)NCBI
Rnor_6.01523,600,518 - 23,610,890 (-)NCBI
Rnor_5.01527,541,333 - 27,555,033 (-)NCBI
RGSC_v3.41522,664,728 - 22,675,100 (-)RGD
Celera1520,468,408 - 20,478,698 (-)RGD
Sequence:
RefSeq Acc Id: XM_063274691   ⟹   XP_063130761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81522,552,377 - 22,560,125 (-)NCBI
RefSeq Acc Id: XM_063274692   ⟹   XP_063130762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81522,552,377 - 22,558,041 (-)NCBI
1 to 10 of 10 rows
Protein RefSeqs NP_112294 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130761 (Get FASTA)   NCBI Sequence Viewer  
  XP_063130762 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81778 (Get FASTA)   NCBI Sequence Viewer  
  CAA77650 (Get FASTA)   NCBI Sequence Viewer  
  EDL88330 (Get FASTA)   NCBI Sequence Viewer  
  EDL88331 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000089942
  ENSRNOP00000089942.1
GenBank Protein Q63228 (Get FASTA)   NCBI Sequence Viewer  
1 to 10 of 10 rows
RefSeq Acc Id: NP_112294   ⟸   NM_031032
- UniProtKB: Q63228 (UniProtKB/Swiss-Prot),   A6KE25 (UniProtKB/TrEMBL),   M0RDJ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067695   ⟸   ENSRNOT00000075602
Ensembl Acc Id: ENSRNOP00000089942   ⟸   ENSRNOT00000101993
Ensembl Acc Id: ENSRNOP00000083410   ⟸   ENSRNOT00000119616
RefSeq Acc Id: XP_063130761   ⟸   XM_063274691
- Peptide Label: isoform X1
ADF-H

Name Modeler Protein Id AA Range Protein Structure
AF-Q63228-F1-model_v2 AlphaFold Q63228 1-142 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen



1 to 29 of 29 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-14171 BioCyc
Ensembl Genes ENSRNOG00000047250 Ensembl
  ENSRNOG00000064480 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000101993 ENTREZGENE
  ENSRNOT00000101993.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7192655 IMAGE-MGC_LOAD
InterPro ADF-H UniProtKB/Swiss-Prot
  ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot
  GMF UniProtKB/Swiss-Prot
KEGG Report rno:81661 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93372 IMAGE-MGC_LOAD
NCBI Gene 81661 ENTREZGENE
PANTHER GLIA MATURATION FACTOR BETA UniProtKB/Swiss-Prot
  PTHR11249 UniProtKB/Swiss-Prot
Pfam Cofilin_ADF UniProtKB/Swiss-Prot
PhenoGen Gmfb PhenoGen
PIRSF GMF-beta UniProtKB/Swiss-Prot
PROSITE ADF_H UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000047250 RatGTEx
  ENSRNOG00000064480 RatGTEx
SMART ADF UniProtKB/Swiss-Prot
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/Swiss-Prot
UniProt A0A8I5ZWW7_RAT UniProtKB/TrEMBL
  A6KE25 ENTREZGENE, UniProtKB/TrEMBL
  A6KE26_RAT UniProtKB/TrEMBL
  GMFB_RAT UniProtKB/Swiss-Prot
  M0RDJ4 ENTREZGENE, UniProtKB/TrEMBL
  Q63228 ENTREZGENE
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Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Gmfb  glia maturation factor, beta      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

Note Type Note Reference
gene_expression mRNA expressed in brain and spinal chord 70747
gene_expression mRNA detected in brain from E10 to postnatal month 14 70747
gene_expression protein level increases slowly through embryonic period to plateau at P7 70747
gene_homology deduced amino acid sequence differed from human homolog in only 3 places; His27 (in place of Asn), Val51 (for Ile), and Leu93 (for Val) 70747