Gmfb (glia maturation factor, beta) - Rat Genome Database

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Gene: Gmfb (glia maturation factor, beta) Rattus norvegicus
Analyze
Symbol: Gmfb
Name: glia maturation factor, beta
RGD ID: 70910
Description: Predicted to enable Arp2/3 complex binding activity. Predicted to be involved in actin filament debranching and negative regulation of Arp2/3 complex-mediated actin nucleation. Predicted to act upstream of or within learning and locomotory behavior. Predicted to be active in cortical actin cytoskeleton. Orthologous to human GMFB (glia maturation factor beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DNA for thyroid hormone receptor binding site (276bp); glia maturation factor beta; GMF-beta; MGC93372
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81522,549,705 - 22,560,125 (-)NCBIGRCr8
mRatBN7.21520,069,923 - 20,081,005 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1520,067,263 - 20,080,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1522,850,667 - 22,860,918 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01523,808,661 - 23,818,912 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01522,058,939 - 22,069,311 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01523,597,846 - 23,611,541 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1523,601,368 - 23,606,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01527,541,333 - 27,555,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41522,664,728 - 22,675,100 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11522,680,429 - 22,690,800 (-)NCBI
Celera1520,468,408 - 20,478,698 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
aflatoxin M1  (ISO)
alpha-Zearalanol  (EXP)
amitrole  (EXP)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
chlorpyrifos  (EXP,ISO)
cisplatin  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
diazinon  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (ISO)
dichlorine  (EXP)
dicrotophos  (ISO)
doxorubicin  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
hydrogen peroxide  (ISO)
hypochlorous acid  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
methamphetamine  (EXP)
methapyrilene  (EXP)
methimazole  (EXP)
methylmercury chloride  (ISO)
monosodium L-glutamate  (ISO)
nickel atom  (ISO)
nicotine  (ISO)
ozone  (EXP,ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorododecanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
resveratrol  (ISO)
rimonabant  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 203580  (ISO)
sevoflurane  (EXP)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trovafloxacin  (ISO)
valproic acid  (ISO)
vincristine  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Gene Data Set MGD Curation, June 12, 2002
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Expression of glia maturation factor beta mRNA and protein in rat organs and cells. Zaheer A, etal., J Neurochem 1993 Mar;60(3):914-20.
Additional References at PubMed
PMID:12477932   PMID:15451385   PMID:15489334   PMID:29476059   PMID:30191459   PMID:31505169   PMID:37121966   PMID:37904673  


Genomics

Comparative Map Data
Gmfb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81522,549,705 - 22,560,125 (-)NCBIGRCr8
mRatBN7.21520,069,923 - 20,081,005 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1520,067,263 - 20,080,331 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1522,850,667 - 22,860,918 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01523,808,661 - 23,818,912 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01522,058,939 - 22,069,311 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01523,597,846 - 23,611,541 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1523,601,368 - 23,606,634 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01527,541,333 - 27,555,033 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41522,664,728 - 22,675,100 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11522,680,429 - 22,690,800 (-)NCBI
Celera1520,468,408 - 20,478,698 (-)NCBICelera
Cytogenetic Map15p14NCBI
GMFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381454,474,485 - 54,488,980 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1454,474,484 - 54,489,025 (-)EnsemblGRCh38hg38GRCh38
GRCh371454,941,203 - 54,955,698 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361454,010,959 - 54,025,494 (-)NCBINCBI36Build 36hg18NCBI36
Build 341454,010,958 - 54,025,494NCBI
Celera1434,990,739 - 35,005,274 (-)NCBICelera
Cytogenetic Map14q22.2NCBI
HuRef1435,103,853 - 35,118,388 (-)NCBIHuRef
CHM1_11454,879,910 - 54,894,446 (-)NCBICHM1_1
T2T-CHM13v2.01448,679,656 - 48,694,147 (-)NCBIT2T-CHM13v2.0
Gmfb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391447,045,606 - 47,059,711 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1447,045,606 - 47,059,699 (-)EnsemblGRCm39 Ensembl
GRCm381446,808,149 - 46,822,259 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1446,808,149 - 46,822,242 (-)EnsemblGRCm38mm10GRCm38
MGSCv371447,427,824 - 47,441,917 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361445,730,026 - 45,744,086 (-)NCBIMGSCv36mm8
Celera1442,976,366 - 42,990,224 (-)NCBICelera
Cytogenetic Map14C1NCBI
cM Map1424.32NCBI
Gmfb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554098,969,398 - 8,984,257 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554098,969,398 - 8,984,008 (+)NCBIChiLan1.0ChiLan1.0
GMFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21555,596,106 - 55,610,916 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11454,812,615 - 54,827,432 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01435,061,469 - 35,076,234 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11453,339,536 - 53,353,873 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1453,343,142 - 53,348,840 (-)Ensemblpanpan1.1panPan2
GMFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1830,394,020 - 30,408,408 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl830,359,499 - 30,408,357 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha830,162,606 - 30,177,006 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0830,651,153 - 30,665,519 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl830,651,155 - 30,665,487 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1830,255,325 - 30,269,686 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0830,331,779 - 30,346,147 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0830,697,308 - 30,711,696 (-)NCBIUU_Cfam_GSD_1.0
Gmfb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864074,839,349 - 74,853,751 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936697613,547 - 625,438 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936697613,535 - 627,906 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GMFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1183,846,680 - 183,863,398 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11183,846,672 - 183,863,396 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GMFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12431,643,202 - 31,655,819 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2431,640,022 - 31,655,768 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605319,872,348 - 19,887,054 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gmfb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473114,790,384 - 14,804,163 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473114,790,338 - 14,804,163 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gmfb
56 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:803
Count of miRNA genes:322
Interacting mature miRNAs:428
Transcripts:ENSRNOT00000075602
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15226636822711984Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151448116528469888Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat

Markers in Region
RH132322  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21520,067,440 - 20,067,634 (+)MAPPERmRatBN7.2
Rnor_6.01523,598,031 - 23,598,224NCBIRnor6.0
Rnor_5.01527,541,518 - 27,541,711UniSTSRnor5.0
RGSC_v3.41522,662,241 - 22,662,434UniSTSRGSC3.4
Celera1520,465,921 - 20,466,114UniSTS
RH 3.4 Map15186.3UniSTS
Cytogenetic Map15p14UniSTS
BE095473  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21520,080,436 - 20,080,602 (+)MAPPERmRatBN7.2
Rnor_6.01523,611,027 - 23,611,192NCBIRnor6.0
Rnor_5.01527,554,514 - 27,554,679UniSTSRnor5.0
RGSC_v3.41522,675,237 - 22,675,402UniSTSRGSC3.4
Celera1520,478,835 - 20,479,000UniSTS
RH 3.4 Map15189.0UniSTS
Cytogenetic Map15p14UniSTS
Gmfb  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21520,069,957 - 20,070,671 (+)MAPPERmRatBN7.2
Rnor_6.01523,600,548 - 23,601,261NCBIRnor6.0
Rnor_5.01527,544,035 - 27,544,748UniSTSRnor5.0
Celera1520,468,438 - 20,469,151UniSTS
Cytogenetic Map15p14UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000075602   ⟹   ENSRNOP00000067695
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1520,070,778 - 20,076,045 (-)Ensembl
Rnor_6.0 Ensembl1523,601,368 - 23,606,634 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101993   ⟹   ENSRNOP00000089942
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1520,067,263 - 20,080,331 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119616   ⟹   ENSRNOP00000083410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1520,067,263 - 20,076,414 (-)Ensembl
RefSeq Acc Id: NM_031032   ⟹   NP_112294
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81522,549,705 - 22,560,077 (-)NCBI
mRatBN7.21520,069,928 - 20,080,300 (-)NCBI
Rnor_6.01523,600,518 - 23,610,890 (-)NCBI
Rnor_5.01527,541,333 - 27,555,033 (-)NCBI
RGSC_v3.41522,664,728 - 22,675,100 (-)RGD
Celera1520,468,408 - 20,478,698 (-)RGD
Sequence:
RefSeq Acc Id: XM_063274691   ⟹   XP_063130761
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81522,552,377 - 22,560,125 (-)NCBI
RefSeq Acc Id: XM_063274692   ⟹   XP_063130762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81522,552,377 - 22,558,041 (-)NCBI
RefSeq Acc Id: NP_112294   ⟸   NM_031032
- UniProtKB: Q63228 (UniProtKB/Swiss-Prot),   A6KE25 (UniProtKB/TrEMBL),   M0RDJ4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000067695   ⟸   ENSRNOT00000075602
Ensembl Acc Id: ENSRNOP00000089942   ⟸   ENSRNOT00000101993
Ensembl Acc Id: ENSRNOP00000083410   ⟸   ENSRNOT00000119616
RefSeq Acc Id: XP_063130761   ⟸   XM_063274691
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063130762   ⟸   XM_063274692
- Peptide Label: isoform X2
Protein Domains
ADF-H

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63228-F1-model_v2 AlphaFold Q63228 1-142 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:70910 AgrOrtholog
BioCyc Gene G2FUF-14171 BioCyc
Ensembl Genes ENSRNOG00000047250 Ensembl
  ENSRNOG00000064480 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055027212 UniProtKB/Swiss-Prot
  ENSRNOG00060023326 UniProtKB/Swiss-Prot
  ENSRNOG00065032462 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000075602.3 UniProtKB/TrEMBL
  ENSRNOT00000101993.1 UniProtKB/Swiss-Prot
  ENSRNOT00000119616.1 UniProtKB/TrEMBL
  ENSRNOT00055047081 UniProtKB/Swiss-Prot
  ENSRNOT00060040468 UniProtKB/Swiss-Prot
  ENSRNOT00065055880 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7192655 IMAGE-MGC_LOAD
InterPro ADF-H UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADF-H/Gelsolin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GMF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81661 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:93372 IMAGE-MGC_LOAD
NCBI Gene 81661 ENTREZGENE
PANTHER GLIA MATURATION FACTOR BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11249 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cofilin_ADF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gmfb PhenoGen
PIRSF GMF-beta UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADF_H UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047250 RatGTEx
  ENSRNOG00000064480 RatGTEx
  ENSRNOG00055027212 RatGTEx
  ENSRNOG00060023326 RatGTEx
  ENSRNOG00065032462 RatGTEx
SMART ADF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Actin depolymerizing proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZWW7_RAT UniProtKB/TrEMBL
  A6KE25 ENTREZGENE, UniProtKB/TrEMBL
  A6KE26_RAT UniProtKB/TrEMBL
  GMFB_RAT UniProtKB/Swiss-Prot
  M0RDJ4 ENTREZGENE, UniProtKB/TrEMBL
  Q63228 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Gmfb  glia maturation factor, beta      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expressed in brain and spinal chord 70747
gene_expression mRNA detected in brain from E10 to postnatal month 14 70747
gene_expression protein level increases slowly through embryonic period to plateau at P7 70747
gene_homology deduced amino acid sequence differed from human homolog in only 3 places; His27 (in place of Asn), Val51 (for Ile), and Leu93 (for Val) 70747