Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Demecolcine results in increased expression of GMFB mRNA | CTD | PMID:23649840 | (1->4)-beta-D-glucan | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GMFB mRNA | CTD | PMID:36331819 | (S)-nicotine | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1,2-dimethylhydrazine | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of GMFB mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | ISO | Gmfb (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of GMFB mRNA | CTD | PMID:22206623 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GMFB mRNA | CTD | PMID:21632981 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GMFB mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of GMFB mRNA | CTD | PMID:15034205 and PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | AHR protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of GMFB mRNA] | CTD | PMID:15034205 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of GMFB mRNA | CTD | PMID:21346803 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of GMFB mRNA | CTD | PMID:21346803 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of GMFB mRNA | CTD | PMID:30047161 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of GMFB mRNA | CTD | PMID:31881176 | aflatoxin M1 | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of GMFB mRNA | CTD | PMID:30928695 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of GMFB mRNA | CTD | PMID:30047161 | atrazine | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | Atrazine results in decreased expression of GMFB mRNA | CTD | PMID:22378314 | benzo[a]pyrene | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | AHR protein promotes the reaction [Benzo(a)pyrene results in decreased expression of GMFB mRNA] | CTD | PMID:15034205 | benzo[a]pyrene | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of GMFB mRNA | CTD | PMID:26238291 | benzo[a]pyrene | decreases expression | ISO | Gmfb (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of GMFB mRNA | CTD | PMID:15034205 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GMFB mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol A | decreases expression | ISO | Gmfb (Mus musculus) | 6480464 | bisphenol A results in decreased expression of GMFB mRNA | CTD | PMID:37894381 | bisphenol A | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of GMFB protein | CTD | PMID:34186270 | bisphenol A | decreases methylation | ISO | GMFB (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of GMFB gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of GMFB mRNA | CTD | PMID:29097150 and PMID:33296240 | bisphenol F | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | bisphenol F results in increased expression of GMFB protein | CTD | PMID:34186270 | butan-1-ol | multiple interactions | ISO | GMFB (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of GMFB mRNA | CTD | PMID:29432896 | cadmium atom | multiple interactions | ISO | GMFB (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GMFB mRNA | CTD | PMID:35301059 | cadmium dichloride | affects expression | EXP | | 6480464 | Cadmium Chloride affects the expression of GMFB mRNA | CTD | PMID:22110744 | cadmium dichloride | multiple interactions | ISO | GMFB (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of GMFB mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | MT3 affects the reaction [Cadmium Chloride affects the expression of GMFB mRNA] | CTD | PMID:20371981 | caffeine | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of GMFB mRNA | CTD | PMID:17452286 | chlorpyrifos | decreases expression | ISO | Gmfb (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of GMFB mRNA | CTD | PMID:37019170 | cisplatin | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of GMFB mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of GMFB mRNA | CTD | PMID:24386269 | copper(II) sulfate | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of GMFB mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of GMFB mRNA | CTD | PMID:25562108 | diazinon | affects expression | EXP | | 6480464 | Diazinon affects the expression of GMFB mRNA | CTD | PMID:17452286 | dibutyl phthalate | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of GMFB mRNA | CTD | PMID:21266533 | dichlorine | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of GMFB mRNA | CTD | PMID:18636392 | dicrotophos | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of GMFB mRNA | CTD | PMID:28302478 | doxorubicin | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of GMFB mRNA | CTD | PMID:29803840 | ethanol | affects expression | ISO | Gmfb (Mus musculus) | 6480464 | Ethanol affects the expression of GMFB mRNA | CTD | PMID:30319688 | ethanol | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of GMFB mRNA | CTD | PMID:30319688 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of GMFB protein | CTD | PMID:33656234 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of GMFB mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of GMFB mRNA] | CTD | PMID:22206623 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of GMFB mRNA | CTD | PMID:25539665 | hydrogen peroxide | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [GMFB protein co-treated with AGT protein] results in increased abundance of Hydrogen Peroxide more ... | CTD | PMID:12791701 | hydrogen peroxide | increases response to substance | ISO | Gmfb (Mus musculus) | 6480464 | GMFB protein results in increased susceptibility to Hydrogen Peroxide | CTD | PMID:12791701 | hypochlorous acid | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | Hypochlorous Acid results in increased expression of GMFB mRNA | CTD | PMID:19376150 | ivermectin | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of GMFB protein | CTD | PMID:32959892 | lead(0) | affects splicing | ISO | GMFB (Homo sapiens) | 6480464 | Lead affects the splicing of GMFB mRNA | CTD | PMID:28903495 | lipopolysaccharide | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | Lipopolysaccharides results in increased expression of GMFB mRNA | CTD | PMID:15919760 | maneb | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] results in decreased expression of GMFB mRNA and [Paraquat co-treated with Maneb] results in decreased expression of GMFB protein | CTD | PMID:17532186 | methamphetamine | affects expression | EXP | | 6480464 | Methamphetamine affects the expression of GMFB protein | CTD | PMID:17904249 | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of GMFB mRNA | CTD | PMID:30467583 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of GMFB mRNA | CTD | PMID:30047161 | methylmercury chloride | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of GMFB mRNA | CTD | PMID:28001369 | monosodium L-glutamate | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [Trans Fatty Acids co-treated with Sodium Glutamate] results in increased expression of GMFB mRNA | CTD | PMID:22078008 | nickel atom | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Nickel results in increased expression of GMFB mRNA | CTD | PMID:24768652 and PMID:25583101 | nicotine | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | ozone | decreases expression | ISO | Gmfb (Mus musculus) | 6480464 | Ozone results in decreased expression of GMFB mRNA | CTD | PMID:17460151 | ozone | multiple interactions | ISO | GMFB (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of GMFB mRNA | CTD | PMID:35430440 | ozone | multiple interactions | EXP | | 6480464 | [Ozone co-treated with Chlorine] results in decreased expression of GMFB mRNA | CTD | PMID:18636392 | paracetamol | affects expression | ISO | Gmfb (Mus musculus) | 6480464 | Acetaminophen affects the expression of GMFB mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of GMFB mRNA | CTD | PMID:21420995 | paraquat | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [Paraquat co-treated with Maneb] results in decreased expression of GMFB mRNA and [Paraquat co-treated with Maneb] results in decreased expression of GMFB protein | CTD | PMID:17532186 | perfluorododecanoic acid | decreases expression | EXP | | 6480464 | perfluorododecanoic acid results in decreased expression of GMFB protein | CTD | PMID:26168851 | perfluorooctane-1-sulfonic acid | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | perfluorooctane sulfonic acid results in decreased expression of GMFB mRNA | CTD | PMID:27153767 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of GMFB mRNA | CTD | PMID:36331819 | perfluorooctanoic acid | increases expression | EXP | | 6480464 | perfluorooctanoic acid results in increased expression of GMFB mRNA | CTD | PMID:19162173 | phenobarbital | decreases expression | ISO | Gmfb (Mus musculus) | 6480464 | Phenobarbital results in decreased expression of GMFB mRNA | CTD | PMID:23091169 | pirinixic acid | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | pirinixic acid results in increased expression of GMFB mRNA | CTD | PMID:17426115 more ... | poly(I:C) | multiple interactions | EXP | | 6480464 | [Poly I-C co-treated with HU 211] results in decreased expression of GMFB mRNA | CTD | PMID:26923065 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of GMFB mRNA | CTD | PMID:19162173 | resveratrol | multiple interactions | ISO | GMFB (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of GMFB mRNA | CTD | PMID:23557933 | rimonabant | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | Rimonabant inhibits the reaction [Dietary Fats results in increased expression of GMFB mRNA] | CTD | PMID:19030233 | S-butyl-DL-homocysteine (S,R)-sulfoximine | increases response to substance | ISO | Gmfb (Mus musculus) | 6480464 | GMFB protein results in increased susceptibility to Buthionine Sulfoximine | CTD | PMID:12791701 | SB 203580 | multiple interactions | ISO | Gmfb (Mus musculus) | 6480464 | SB 203580 inhibits the reaction [[GMFB protein co-treated with Hydrogen Peroxide] results in increased abundance of Hydrogen Peroxide] and SB 203580 inhibits the reaction [[GMFB protein co-treated with Hydrogen Peroxide] results in increased activity of CASP3 protein] | CTD | PMID:12791701 | sevoflurane | affects expression | EXP | | 6480464 | sevoflurane affects the expression of GMFB mRNA | CTD | PMID:15967596 | sodium arsenate | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | sodium arsenate results in increased expression of GMFB mRNA | CTD | PMID:21795629 | sodium dichromate | increases expression | EXP | | 6480464 | sodium bichromate results in increased expression of GMFB mRNA | CTD | PMID:25993096 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of GMFB mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Sunitinib results in increased expression of GMFB mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of GMFB mRNA | CTD | PMID:31758290 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of GMFB mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | affects expression | ISO | Gmfb (Mus musculus) | 6480464 | Trichloroethylene affects the expression of GMFB mRNA | CTD | PMID:21135412 | trovafloxacin | increases expression | ISO | Gmfb (Mus musculus) | 6480464 | trovafloxacin results in increased expression of GMFB mRNA | CTD | PMID:35537566 | valproic acid | affects expression | ISO | GMFB (Homo sapiens) | 6480464 | Valproic Acid affects the expression of GMFB mRNA | CTD | PMID:25979313 | vincristine | increases expression | ISO | GMFB (Homo sapiens) | 6480464 | Vincristine results in increased expression of GMFB mRNA | CTD | PMID:23649840 | vorinostat | decreases expression | ISO | GMFB (Homo sapiens) | 6480464 | vorinostat results in decreased expression of GMFB protein | CTD | PMID:20543569 | zinc atom | multiple interactions | ISO | GMFB (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of GMFB mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | GMFB (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of GMFB mRNA | CTD | PMID:18593933 | |