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Gene: Flnb (filamin B) Rattus norvegicus
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Symbol: Flnb
Name: filamin B
Description: Predicted to have identical protein binding activity. Predicted to be involved in several processes, including cellular response to interferon-gamma; epithelial cell development; and skeletal muscle tissue development. Localizes to the neuron projection; neuronal cell body; and nucleus. Human ortholog(s) of this gene implicated in Larsen syndrome; bone development disease (multiple); cleft palate; and spinal disease. Orthologous to human FLNB (filamin B); PARTICIPATES IN integrin mediated signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: filamin B, beta; filamin, beta; filamin-B; LOC306204
Orthologs:
Homo sapiens (human) : FLNB (filamin B)  HGNC  Alliance
Mus musculus (house mouse) : Flnb (filamin, beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Flnb (filamin B)
Pan paniscus (bonobo/pygmy chimpanzee) : FLNB (filamin B)
Canis lupus familiaris (dog) : FLNB (filamin B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Flnb (filamin B)
Sus scrofa (pig) : FLNB (filamin B)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01518,750,152 - 18,883,019 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01522,716,606 - 22,849,401 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41518,949,027 - 19,082,504 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11518,950,017 - 19,108,490 (-)NCBI
Celera1516,918,384 - 17,051,016 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Flnb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311915
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.