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Gene: Gja3 (gap junction protein, alpha 3) Rattus norvegicus
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Symbol: Gja3
Name: gap junction protein, alpha 3
Description: Exhibits gap junction hemi-channel activity and identical protein binding activity. Involved in response to hydrogen peroxide and response to pH. Localizes to gap junction and membrane raft. Used to study cataract. Human ortholog(s) of this gene implicated in cataract 14 multiple types. Orthologous to human GJA3 (gap junction protein alpha 3); INTERACTS WITH 6-propyl-2-thiouracil; acrylamide; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: connexin 46; connexin j1; connexin-46; cx46; Cxnj1; gap junction alpha-3 protein; gap junction membrane channel protein alpha 3
Orthologs:
Homo sapiens (human) : GJA3 (gap junction protein alpha 3)  HGNC  Alliance
Mus musculus (house mouse) : Gja3 (gap junction protein, alpha 3)  MGI  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : GJA3 (gap junction protein alpha 3)
Canis lupus familiaris (dog) : GJA3 (gap junction protein alpha 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gja3 (gap junction protein alpha 3)
Sus scrofa (pig) : GJA3 (gap junction protein alpha 3)
Chlorocebus sabaeus (African green monkey) : GJA3 (gap junction protein alpha 3)
Heterocephalus glaber (naked mole-rat) : Gja3 (gap junction protein alpha 3)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01537,298,607 - 37,325,370 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1537,299,738 - 37,325,178 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01541,146,019 - 41,172,888 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41536,052,554 - 36,078,001 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11536,068,253 - 36,093,701 (-)NCBI
Celera1530,893,821 - 30,919,252 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Gja3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621820
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.