GJA3 (gap junction protein alpha 3) - Rat Genome Database

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Gene: GJA3 (gap junction protein alpha 3) Chlorocebus sabaeus
Analyze
Symbol: GJA3
Name: gap junction protein alpha 3
RGD ID: 18498132
Description: ENCODES a protein that exhibits gap junction channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN response to hydrogen peroxide (ortholog); response to pH (ortholog); ASSOCIATED WITH autosomal dominant nonsyndromic deafness 3B (ortholog); autosomal recessive nonsyndromic deafness 1A (ortholog); autosomal recessive nonsyndromic deafness 1B (ortholog); FOUND IN gap junction (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: gap junction alpha-3 protein
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChlSab1.1 - Green Monkey 1.1 Assembly
Position:
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.13820,352 - 852,003 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl3846,982 - 848,286 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605743,732,906 - 43,755,939 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
GJA3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.13820,352 - 852,003 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl3846,982 - 848,286 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605743,732,906 - 43,755,939 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
GJA3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381320,138,255 - 20,161,565 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1320,138,255 - 20,161,052 (-)EnsemblGRCh38hg38GRCh38
GRCh371320,712,394 - 20,735,191 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361319,610,394 - 19,633,183 (-)NCBINCBI36Build 36hg18NCBI36
Build 341319,614,119 - 19,615,427NCBI
Celera131,774,203 - 1,796,991 (-)NCBICelera
Cytogenetic Map13q12.11NCBI
HuRef131,517,843 - 1,540,632 (-)NCBIHuRef
CHM1_11320,680,889 - 20,703,688 (-)NCBICHM1_1
T2T-CHM13v2.01319,334,689 - 19,357,997 (-)NCBIT2T-CHM13v2.0
Gja3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391457,271,917 - 57,295,487 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1457,271,917 - 57,295,557 (-)EnsemblGRCm39 Ensembl
GRCm381457,034,460 - 57,058,030 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1457,034,460 - 57,058,100 (-)EnsemblGRCm38mm10GRCm38
MGSCv371457,654,497 - 57,676,782 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361455,989,770 - 56,012,055 (-)NCBIMGSCv36mm8
Celera1454,826,204 - 54,848,538 (-)NCBICelera
Cytogenetic Map14C3NCBI
cM Map1429.82NCBI
Gja3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81535,296,946 - 35,322,405 (-)NCBIGRCr8
mRatBN7.21531,181,360 - 31,206,820 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1531,181,369 - 31,206,810 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1533,172,676 - 33,198,138 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01534,323,331 - 34,348,793 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01532,581,458 - 32,606,917 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01537,298,607 - 37,325,370 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1537,299,738 - 37,325,178 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01541,146,019 - 41,172,888 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41536,052,554 - 36,078,001 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11536,068,253 - 36,093,701 (-)NCBI
Celera1530,893,821 - 30,919,252 (-)NCBICelera
Cytogenetic Map15p12NCBI
GJA3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21419,771,129 - 19,791,424 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11310,875,614 - 10,903,716 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0131,464,542 - 1,488,240 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11319,780,656 - 19,803,446 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1319,784,372 - 19,785,679 (-)Ensemblpanpan1.1panPan2
GJA3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12517,986,270 - 18,004,344 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2518,002,817 - 18,004,160 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2518,016,882 - 18,034,847 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02518,124,207 - 18,142,180 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2518,124,215 - 18,143,066 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12517,990,559 - 18,008,503 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02518,002,295 - 18,020,235 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02518,058,980 - 18,076,953 (+)NCBIUU_Cfam_GSD_1.0
Gja3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945120,017,114 - 120,040,168 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367201,583,588 - 1,584,904 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367201,564,680 - 1,586,379 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GJA3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl11750,658 - 751,800 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.111750,658 - 751,889 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Gja3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477617,579,913 - 17,581,121 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477617,562,050 - 17,585,308 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression

ectoderm
endocrine system
hemolymphoid system
mesenchyme
mesoderm
nervous system
reproductive system
76 36 18 34 34 60 20

Sequence


Ensembl Acc Id: ENSCSAT00000018677   ⟹   ENSCSAP00000018120
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.1 Ensembl3846,982 - 848,286 (+)Ensembl
RefSeq Acc Id: XM_008021675   ⟹   XP_008019866
Type: CODING
Position:
Green Monkey AssemblyChrPosition (strand)Source
ChlSab1.13829,534 - 852,003 (+)NCBI
Vero_WHO_p1.0NW_02366605743,732,906 - 43,755,939 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008019866 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCSAP00000018120.1
RefSeq Acc Id: XP_008019866   ⟸   XM_008021675
- UniProtKB: A0A0D9SB81 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSCSAP00000018120   ⟸   ENSCSAT00000018677


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCSAG00000018587 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCSAT00000018677.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1440.80 UniProtKB/TrEMBL
InterPro Connexin UniProtKB/TrEMBL
  Connexin46 UniProtKB/TrEMBL
  Connexin_C UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
  Connexin_CS UniProtKB/TrEMBL
  Connexin_N UniProtKB/TrEMBL
  Connexin_N_sf UniProtKB/TrEMBL
KEGG Report csab:103248968 UniProtKB/TrEMBL
NCBI Gene GJA3 ENTREZGENE
PANTHER PTHR11984 UniProtKB/TrEMBL
  PTHR11984:SF12 UniProtKB/TrEMBL
Pfam Connexin UniProtKB/TrEMBL
PRINTS CONNEXIN UniProtKB/TrEMBL
  CONNEXINA3 UniProtKB/TrEMBL
PROSITE CONNEXINS_1 UniProtKB/TrEMBL
  CONNEXINS_2 UniProtKB/TrEMBL
SMART CNX UniProtKB/TrEMBL
  Connexin_CCC UniProtKB/TrEMBL
Superfamily-SCOP SSF118220 UniProtKB/TrEMBL
UniProt A0A0D9SB81 ENTREZGENE, UniProtKB/TrEMBL