Gene: Psmd6 (proteasome 26S subunit, non-ATPase 6) Rattus norvegicus
Analyze
Symbol:
Psmd6
Name:
proteasome 26S subunit, non-ATPase 6
Description:
Predicted to have enzyme regulator activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to localize to the proteasome regulatory particle. Orthologous to human PSMD6 (proteasome 26S subunit, non-ATPase 6); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
26S proteasome non-ATPase regulatory subunit 6; MGC72968; P44s10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 6; proteasome regulatory particle subunit p44S10; proteasome, 26S, non-ATPase regulatory subunit 6; Unknown (protein for MGC:72968)
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
PSMD6 (proteasome 26S subunit, non-ATPase 6) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):
Psmd6 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 6) HGNC
Treefam, EggNOG, OrthoMCL, NCBI, OMA, HomoloGene, Inparanoid, Panther, PhylomeDB, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Psmd6 (proteasome 26S subunit, non-ATPase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
PSMD6 (proteasome 26S subunit, non-ATPase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
PSMD6 (proteasome 26S subunit, non-ATPase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Psmd6 (proteasome 26S subunit, non-ATPase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
PSMD6 (proteasome 26S subunit, non-ATPase 6) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
PSMD6 (proteasome 26S subunit, non-ATPase 6)
Alliance
DIOPT (Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Mus musculus (house mouse):
Psmd6 (proteasome (prosome, macropain) 26S subunit, non-ATPase, 6)
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Danio rerio (zebrafish):
psmd6 (proteasome 26S subunit, non-ATPase 6)
Alliance
DIOPT (Ensembl Compara, Hieranoid, OMA, OrthoFinder, PANTHER, PhylomeDB, TreeFam)
Caenorhabditis elegans (roundworm):
rpn-7
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB)
Saccharomyces cerevisiae (baker's yeast):
RPN7
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Drosophila melanogaster (fruit fly):
Rpn7
Alliance
DIOPT (Ensembl Compara, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, TreeFam)
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 15 12,407,557 - 12,416,153 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 12,407,524 - 12,416,105 (+) Ensembl Rnor_5.0 15 16,438,829 - 16,447,425 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 15 12,650,570 - 12,660,487 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 15 12,650,569 - 12,660,487 (+) NCBI Celera 15 11,109,222 - 11,119,073 (+) NCBI Celera Cytogenetic Map 15 p16 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Disease Annotations
Gene-Chemical Interaction Annotations
(+)-schisandrin B multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PSMD6 mRNA] CTD PMID:31150632 17alpha-ethynylestradiol affects expression ISO RGD:1553613 6480464 Ethinyl Estradiol affects the expression of PSMD6 mRNA CTD PMID:17555576 17beta-estradiol increases expression ISO RGD:1351950 6480464 Estradiol results in increased expression of PSMD6 mRNA CTD PMID:16514628 17beta-estradiol multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PSMD6 mRNA CTD PMID:26496021 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases expression ISO RGD:1351950 6480464 Metribolone results in increased expression of PSMD6 mRNA CTD PMID:17010196 1H-pyrazole increases expression ISO RGD:1553613 6480464 pyrazole results in increased expression of PSMD6 mRNA CTD PMID:17945193 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1553613 6480464 Tetrachlorodibenzodioxin affects the expression of PSMD6 mRNA CTD PMID:21570461 2,4-dinitrotoluene affects expression EXP 6480464 2, 4-dinitrotoluene affects the expression of PSMD6 mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression EXP 6480464 2, 6-dinitrotoluene affects the expression of PSMD6 mRNA CTD PMID:21346803 afimoxifene decreases expression ISO RGD:1351950 6480464 afimoxifene results in decreased expression of PSMD6 mRNA CTD PMID:16514628 Aroclor 1254 decreases expression ISO RGD:1553613 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of PSMD6 mRNA CTD PMID:23650126 benzo[a]pyrene increases expression ISO RGD:1553613 6480464 Benzo(a)pyrene results in increased expression of PSMD6 mRNA CTD PMID:22228805 bis(2-chloroethyl) sulfide increases expression ISO RGD:1351950 6480464 Mustard Gas results in increased expression of PSMD6 mRNA CTD PMID:12884408 bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of PSMD6 mRNA CTD PMID:26496021 bisphenol A decreases expression ISO RGD:1351950 6480464 bisphenol A results in decreased expression of PSMD6 mRNA CTD PMID:29275510 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PSMD6 mRNA CTD PMID:25181051 C60 fullerene increases expression EXP 6480464 fullerene C60 results in increased expression of PSMD6 mRNA CTD PMID:19167457 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of PSMD6 mRNA CTD PMID:17327699 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of PSMD6 mRNA CTD PMID:17327699 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of PSMD6 promoter CTD PMID:22457795 cadmium dichloride affects localization ISO RGD:1351950 6480464 Cadmium Chloride affects the localization of PSMD6 protein CTD PMID:18261755 carbon nanotube increases expression ISO RGD:1553613 6480464 Nanotubes, Carbon analog results in increased expression of PSMD6 mRNA, Nanotubes, Carbon results in increased expression of PSMD6 mRNA CTD PMID:25554681 chromium(6+) affects expression ISO RGD:1553613 6480464 chromium hexavalent ion affects the expression of PSMD6 mRNA CTD PMID:28472532 clobetasol increases expression ISO RGD:1553613 6480464 Clobetasol results in increased expression of PSMD6 mRNA CTD PMID:27462272 cobalt dichloride increases expression ISO RGD:1351950 6480464 cobaltous chloride results in increased expression of PSMD6 mRNA CTD PMID:19320972 , PMID:19376846 copper(II) sulfate decreases expression ISO RGD:1351950 6480464 Copper Sulfate results in decreased expression of PSMD6 mRNA CTD PMID:19549813 crocidolite asbestos increases expression ISO RGD:1351950 6480464 Asbestos, Crocidolite results in increased expression of PSMD6 mRNA CTD PMID:29523930 dibutyl phthalate decreases expression ISO RGD:1553613 6480464 Dibutyl Phthalate results in decreased expression of PSMD6 mRNA CTD PMID:17361019 dicrotophos decreases expression ISO RGD:1351950 6480464 dicrotophos results in decreased expression of PSMD6 mRNA CTD PMID:28302478 elemental selenium increases expression ISO RGD:1351950 6480464 Selenium results in increased expression of PSMD6 mRNA CTD PMID:19244175 ethanol increases expression ISO RGD:1553613 6480464 Ethanol results in increased expression of PSMD6 mRNA CTD PMID:30319688 finasteride increases expression EXP 6480464 Finasteride results in increased expression of PSMD6 mRNA CTD PMID:24136188 flutamide increases expression EXP 6480464 Flutamide results in increased expression of PSMD6 mRNA CTD PMID:24136188 fulvestrant decreases expression ISO RGD:1351950 6480464 fulvestrant results in decreased expression of PSMD6 mRNA CTD PMID:16514628 nefazodone increases expression EXP 6480464 nefazodone results in increased expression of PSMD6 mRNA CTD PMID:24136188 nickel atom increases expression ISO RGD:1351950 6480464 Nickel results in increased expression of PSMD6 mRNA CTD PMID:25583101 nimesulide increases expression EXP 6480464 nimesulide results in increased expression of PSMD6 mRNA CTD PMID:24136188 perfluorooctane-1-sulfonic acid affects expression ISO RGD:1553613 6480464 perfluorooctane sulfonic acid affects the expression of PSMD6 mRNA CTD PMID:19429403 perfluorooctane-1-sulfonic acid multiple interactions ISO RGD:1553613 6480464 PPARA protein promotes the reaction [perfluorooctane sulfonic acid results in increased expression of PSMD6 mRNA] CTD PMID:20936131 perfluorooctane-1-sulfonic acid increases expression ISO RGD:1553613 6480464 perfluorooctane sulfonic acid results in increased expression of PSMD6 mRNA CTD PMID:20936131 perfluorooctanoic acid affects expression ISO RGD:1553613 6480464 perfluorooctanoic acid affects the expression of PSMD6 mRNA CTD PMID:19429403 phenacetin increases expression EXP 6480464 Phenacetin results in increased expression of PSMD6 mRNA CTD PMID:17082564 phenylhydrazine increases expression EXP 6480464 phenylhydrazine results in increased expression of PSMD6 mRNA CTD PMID:17082564 phlorizin increases expression ISO RGD:1553613 6480464 Phlorhizin results in increased expression of PSMD6 mRNA CTD PMID:22538082 pirinixic acid increases expression ISO RGD:1553613 6480464 pirinixic acid results in increased expression of PSMD6 mRNA CTD PMID:23811191 propiconazole increases expression ISO RGD:1553613 6480464 propiconazole results in increased expression of PSMD6 mRNA CTD PMID:21278054 raloxifene decreases expression ISO RGD:1351950 6480464 Raloxifene Hydrochloride results in decreased expression of PSMD6 mRNA CTD PMID:16514628 selenium atom increases expression ISO RGD:1351950 6480464 Selenium results in increased expression of PSMD6 mRNA CTD PMID:19244175 tetrachloromethane multiple interactions EXP 6480464 schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of PSMD6 mRNA] CTD PMID:31150632 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PSMD6 mRNA CTD PMID:31150632 trichloroethene affects expression ISO RGD:1553613 6480464 Trichloroethylene affects the expression of PSMD6 mRNA CTD PMID:21135412 valdecoxib increases expression EXP 6480464 valdecoxib results in increased expression of PSMD6 mRNA CTD PMID:24136188 valproic acid increases expression ISO RGD:1351950 6480464 Valproic Acid results in increased expression of PSMD6 mRNA CTD PMID:23179753 valproic acid affects expression ISO RGD:1351950 6480464 Valproic Acid affects the expression of PSMD6 mRNA CTD PMID:25979313 vinclozolin decreases expression EXP 6480464 vinclozolin results in decreased expression of PSMD6 mRNA CTD PMID:23555832 vorinostat decreases expression ISO RGD:1351950 6480464 vorinostat results in decreased expression of PSMD6 mRNA CTD PMID:27188386 
Gene-Chemical Interaction Annotations
