Gene: Kcnma1 (potassium calcium-activated channel subfamily M alpha 1) Rattus norvegicus
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Symbol:
Kcnma1
Name:
potassium calcium-activated channel subfamily M alpha 1
Description:
Exhibits identical protein binding activity; large conductance calcium-activated potassium channel activity; and ligand-gated ion channel activity involved in regulation of presynaptic membrane potential. Involved in several processes, including negative regulation of small intestine smooth muscle contraction; positive regulation of neuron apoptotic process; and response to estrogen. Localizes to several cellular components, including external side of plasma membrane; glutamatergic synapse; and integral component of presynaptic active zone membrane. Colocalizes with mitochondrion. Human ortholog(s) of this gene implicated in Alzheimer's disease and idiopathic generalized epilepsy. Orthologous to human KCNMA1 (potassium calcium-activated channel subfamily M alpha 1); INTERACTS WITH (+)-pilocarpine; (+)-Pimaric acid; (R)-noradrenaline.
Type:
protein-coding
RefSeq Status:
PROVISIONAL
Also known as:
BK channel; BKCa; BKCA alpha; calcium-activated potassium channel alpha subunit; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; cbv1; k(VCA)alpha; KCa1.1; Kcnma; KCNMA1b; KCNMA1c; LOC498438; maxi K channel; maxiK; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; similar to potassium large conductance calcium-activated channel, subfamily M, alpha member 1; Slo; slo homolog; slo-alpha; slo1; slowpoke homolog
Orthologs:
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Homo sapiens (human):
KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, OMA, OrthoDB, Panther
Mus musculus (house mouse):
Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1) HGNC
EggNOG, OMA, HomoloGene, Inparanoid, Panther, OrthoDB, Ensembl
Chinchilla lanigera (long-tailed chinchilla):
Kcnma1 (potassium calcium-activated channel subfamily M alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):
KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Canis lupus familiaris (dog):
KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Kcnma1 (potassium calcium-activated channel subfamily M alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Sus scrofa (pig):
KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Chlorocebus sabaeus (African green monkey):
KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):
Kcnma1 (potassium calcium-activated channel subfamily M alpha 1) Transitive Ortholog Pipeline
Transitive Ortholog Pipeline
Alliance orthologs 3
Homo sapiens (human):
KCNMA1 (potassium calcium-activated channel subfamily M alpha 1)
Alliance
DIOPT (Ensembl Compara|InParanoid|PhylomeDB|OMA|PANTHER|OrthoFinder|HGNC|OrthoInspector|Hieranoid)
Mus musculus (house mouse):
Kcnma1 (potassium large conductance calcium-activated channel, subfamily M, alpha member 1)
Alliance
DIOPT (Ensembl Compara|InParanoid|PhylomeDB|OMA|PANTHER|OrthoFinder|OrthoInspector|Hieranoid)
Danio rerio (zebrafish):
kcnma1a (potassium large conductance calcium-activated channel, subfamily M, alpha member 1a)
Alliance
DIOPT (Ensembl Compara|InParanoid|OMA|PANTHER|OrthoInspector|OrthoFinder|Hieranoid)
Caenorhabditis elegans (roundworm):
slo-1
Alliance
DIOPT (InParanoid|PhylomeDB|OMA|PANTHER|OrthoInspector|OrthoFinder|Hieranoid)
Drosophila melanogaster (fruit fly):
slo
Alliance
DIOPT (InParanoid|PhylomeDB|OMA|PANTHER|OrthoInspector|OrthoFinder|Hieranoid)
Allele / Splice:
Kcnma1_v1
Kcnma1_v2
Latest Assembly:
Rnor_6.0 - RGSC Genome Assembly v6.0
NCBI Annotation Information:
Annotation category: partial on reference assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl Rnor_6.0 15 344,204 - 1,048,849 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 15 344,360 - 1,047,956 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 15 339,100 - 1,037,105 (+) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 RGSC_v3.4 15 575,136 - 950,275 (+) NCBI RGSC3.4 rn4 RGSC3.4 RGSC_v3.1 15 322,288 - 950,273 NCBI Celera 15 3,556,267 - 4,246,392 (-) NCBI Celera Cytogenetic Map 15 p16 NCBI
JBrowse:
View Region in Genome Browser (JBrowse)
Model
Imported Annotations - ClinVar
autism spectrum disorder ISO RGD:731981 8554872 ClinVar Annotator: match by term: Autism spectrum disorders ClinVar PMID:25741868 , PMID:27569545 CEREBELLAR ATROPHY, DEVELOPMENTAL DELAY, AND SEIZURES ISO RGD:731981 8554872 ClinVar Annotator: match by term: CEREBELLAR ATROPHY, DEVELOPMENTAL DELAY, AND SEIZURES ClinVar PMID:27567911 CEREBELLAR ATROPHY, DEVELOPMENTAL DELAY, AND SEIZURES ISO RGD:731981 8554872 ClinVar Annotator: match by term: CEREBELLAR ATROPHY, DEVELOPMENTAL DELAY, AND SEIZURES ClinVar PMID:29545233 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:25741868 more ... Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:26467025 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:25741868 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:25326635 , PMID:25741868 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Paroxysmal nonkinesigenic dyskinesia, 3, with or without generalized epilepsy ClinVar PMID:28492532 , PMID:29933521 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Paroxysmal nonkinesigenic dyskinesia, 3, with or without generalized epilepsy ClinVar PMID:18414213 more ... Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:18414213 , PMID:28492532 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Paroxysmal nonkinesigenic dyskinesia, 3, with or without generalized epilepsy ClinVar PMID:28492532 , PMID:29330545 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:25741868 , PMID:28492532 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:26195193 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:26467025 , PMID:28492532 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by OMIM:609446 ClinVar PMID:15937479 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by OMIM:609446 ClinVar PMID:25326637 Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Generalized epilepsy and paroxysmal dyskinesia ClinVar PMID:28492532 genetic disease ISO RGD:731981 8554872 ClinVar Annotator: match by term: Inborn genetic diseases ClinVar PMID:12366739 more ... Liang-Wang Syndrome ISO RGD:731981 8554872 ClinVar Annotator: match by term: LIANG-WANG SYNDROME ClinVar PMID:12366739 more ... spastic ataxia ISO RGD:731981 8554872 ClinVar Annotator: match by term: Spastic ataxia ClinVar PMID:25741868
Imported Annotations - CTD
autistic disorder ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:16946189 Diaphragmatic Hernia ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:15088113 Growth Disorders ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:28242822 Metabolic Bone Diseases ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21695131 morbid obesity ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:21708048 obesity ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:27605626 Perinatal Death ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:28242822 pulmonary hypertension ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:28090300 renal cell carcinoma ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:23797736 status epilepticus ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:18695509 Weight Gain ISO RGD:731981 11554173 CTD Direct Evidence: marker/mechanism CTD PMID:27605626 Imported Annotations - OMIM
CEREBELLAR ATROPHY, DEVELOPMENTAL DELAY, AND SEIZURES ISO RGD:731981 7240710 OMIM Generalized Epilepsy and Paroxysmal Dyskinesia ISO RGD:731981 7240710 OMIM Idiopathic Generalized Epilepsy 16 susceptibility ISO RGD:731981 7240710 OMIM Liang-Wang Syndrome ISO RGD:731981 7240710 OMIM
(+)-pilocarpine decreases expression EXP 6480464 Pilocarpine results in decreased expression of KCNMA1 mRNA CTD PMID:18695509 (+)-Pimaric acid affects response to substance EXP 6480464 KCNMA1 mRNA affects the susceptibility to pimaric acid CTD PMID:19247476 (R)-noradrenaline affects response to substance EXP 6480464 KCNMA1 protein affects the susceptibility to Norepinephrine CTD PMID:22226998 1,2-dichloroethane increases expression ISO RGD:731982 6480464 ethylene dichloride results in increased expression of KCNMA1 mRNA CTD PMID:28189721 , PMID:28960355 17alpha-ethynylestradiol decreases expression EXP 6480464 Ethinyl Estradiol results in decreased expression of KCNMA1 mRNA CTD PMID:17557909 17beta-estradiol increases activity ISO RGD:731981 6480464 Estradiol results in increased activity of KCNMA1 protein CTD PMID:18068743 17beta-estradiol multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [Estradiol results in decreased expression of KCNMA1 mRNA alternative form] more ... CTD PMID:16102753 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of KCNMA1 mRNA more ... CTD PMID:16102753 17beta-estradiol multiple interactions ISO RGD:731981 6480464 [Estradiol co-treated with Progesterone] results in increased expression of KCNMA1 mRNA more ... CTD PMID:18068743 more ... 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:731981 6480464 Dihydrotestosterone results in increased expression of KCNMA1 mRNA CTD PMID:29581250 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:731982 6480464 [2 more ... CTD PMID:25510870 2,2',5,5'-tetrachlorobiphenyl multiple interactions ISO RGD:731982 6480464 [2 more ... CTD PMID:25510870 2-methylcholine affects expression ISO RGD:731981 6480464 beta-methylcholine affects the expression of KCNMA1 mRNA CTD PMID:21179406 3,3',5-triiodo-L-thyronine multiple interactions ISO RGD:731982 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 mRNA, [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 protein CTD PMID:27605626 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:731982 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 mRNA, [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 protein CTD PMID:27605626 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:731981 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of KCNMA1 mRNA CTD PMID:28628672 4,4'-sulfonyldiphenol increases expression ISO RGD:731982 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of KCNMA1 mRNA CTD PMID:31881267 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of KCNMA1 mRNA CTD PMID:24780913 acetylcholine affects response to substance EXP 6480464 KCNMA1 protein affects the susceptibility to Acetylcholine CTD PMID:22226998 aflatoxin B1 increases expression ISO RGD:731982 6480464 Aflatoxin B1 results in increased expression of KCNMA1 mRNA CTD PMID:19770486 aflatoxin B1 decreases methylation ISO RGD:731981 6480464 Aflatoxin B1 results in decreased methylation of KCNMA1 exon CTD PMID:30157460 aflatoxin B1 affects methylation ISO RGD:731981 6480464 Aflatoxin B1 affects the methylation of KCNMA1 intron CTD PMID:30157460 aflatoxin B1 decreases expression ISO RGD:731981 6480464 Aflatoxin B1 results in decreased expression of KCNMA1 mRNA CTD PMID:31555880 aflatoxin B2 affects methylation ISO RGD:731981 6480464 aflatoxin B2 affects the methylation of KCNMA1 intron CTD PMID:30157460 aldehydo-D-glucose multiple interactions ISO RGD:731981 6480464 Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein] more ... CTD PMID:21413024 all-trans-retinoic acid decreases expression ISO RGD:731981 6480464 Tretinoin results in decreased expression of KCNMA1 mRNA CTD PMID:23724009 amiodarone increases expression ISO RGD:731981 6480464 Amiodarone results in increased expression of KCNMA1 mRNA CTD PMID:19774075 arsane affects methylation ISO RGD:731981 6480464 Arsenic affects the methylation of KCNMA1 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:731981 6480464 Arsenic affects the methylation of KCNMA1 gene CTD PMID:25304211 arsenous acid increases expression ISO RGD:731981 6480464 Arsenic Trioxide results in increased expression of KCNMA1 mRNA CTD PMID:20458559 benzo[a]pyrene decreases expression ISO RGD:731981 6480464 Benzo(a)pyrene results in decreased expression of KCNMA1 mRNA CTD PMID:20064835 more ... benzo[a]pyrene affects methylation ISO RGD:731981 6480464 Benzo(a)pyrene affects the methylation of KCNMA1 intron CTD PMID:30157460 benzo[a]pyrene increases expression ISO RGD:731982 6480464 Benzo(a)pyrene results in increased expression of KCNMA1 mRNA CTD PMID:22228805 benzo[e]pyrene affects methylation ISO RGD:731981 6480464 benzo(e)pyrene affects the methylation of KCNMA1 intron CTD PMID:30157460 bexarotene multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in decreased expression of KCNMA1 mRNA CTD PMID:17630414 bis(2-chloroethyl) sulfide decreases expression ISO RGD:731981 6480464 Mustard Gas results in decreased expression of KCNMA1 mRNA CTD PMID:25102026 bis(2-ethylhexyl) phthalate decreases expression EXP 6480464 Diethylhexyl Phthalate results in decreased expression of KCNMA1 mRNA CTD PMID:20920545 bis(2-ethylhexyl) phthalate increases expression ISO RGD:731981 6480464 Diethylhexyl Phthalate results in increased expression of KCNMA1 mRNA CTD PMID:31163220 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of KCNMA1 mRNA CTD PMID:25181051 , PMID:30816183 bisphenol A decreases expression ISO RGD:731982 6480464 bisphenol A results in decreased expression of KCNMA1 mRNA CTD PMID:31250031 bisphenol A multiple interactions ISO RGD:731982 6480464 ESR2 protein affects the reaction [bisphenol A results in decreased expression of KCNMA1 mRNA] CTD PMID:31250031 bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of KCNMA1 gene CTD PMID:28505145 buta-1,3-diene decreases expression ISO RGD:731982 6480464 1, 3-butadiene results in decreased expression of KCNMA1 mRNA CTD PMID:29038090 cadmium dichloride decreases methylation EXP 6480464 Cadmium Chloride results in decreased methylation of KCNMA1 promoter CTD PMID:22457795 caesium atom affects activity ISO RGD:731982 6480464 Cesium affects the activity of KCNMA1 protein CTD PMID:16636204 calcium atom increases response to substance EXP 6480464 KCNMA1 mRNA alternative form results in increased susceptibility to Calcium CTD PMID:28090300 calcium atom increases response to substance ISO RGD:731981 6480464 KCNMA1 mRNA alternative form results in increased susceptibility to Calcium CTD PMID:28090300 calcium atom multiple interactions ISO RGD:731981 6480464 [KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium, Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] CTD PMID:22123969 calcium(0) multiple interactions ISO RGD:731981 6480464 [KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium, Lithocholic Acid promotes the reaction [[KCNMB1 protein co-treated with KCNMA1 protein] results in increased transport of Calcium] CTD PMID:22123969 calcium(0) increases response to substance EXP 6480464 KCNMA1 mRNA alternative form results in increased susceptibility to Calcium CTD PMID:28090300 calcium(0) increases response to substance ISO RGD:731981 6480464 KCNMA1 mRNA alternative form results in increased susceptibility to Calcium CTD PMID:28090300 cisplatin multiple interactions ISO RGD:731981 6480464 [Piroxicam co-treated with Cisplatin] results in increased expression of KCNMA1 mRNA more ... CTD PMID:21858171 , PMID:27392435 cisplatin decreases expression ISO RGD:731981 6480464 Cisplatin results in decreased expression of KCNMA1 mRNA CTD PMID:19561079 , PMID:27392435 clothianidin decreases expression ISO RGD:731981 6480464 clothianidin results in decreased expression of KCNMA1 mRNA CTD PMID:31626844 copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of KCNMA1 mRNA CTD PMID:26033743 copper atom multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of KCNMA1 mRNA CTD PMID:26033743 copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of KCNMA1 mRNA CTD PMID:26033743 copper(0) multiple interactions EXP 6480464 [Copper co-treated with Dietary Sucrose] results in increased expression of KCNMA1 mRNA CTD PMID:26033743 D-glucose multiple interactions ISO RGD:731981 6480464 Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein] more ... CTD PMID:21413024 decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of KCNMA1 mRNA CTD PMID:23914054 dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNMA1 mRNA], Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNMA1 protein] CTD PMID:15088113 dexamethasone multiple interactions ISO RGD:731981 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of KCNMA1 mRNA CTD PMID:28628672 dexamethasone multiple interactions ISO RGD:731982 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 mRNA, [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 protein CTD PMID:27605626 diarsenic trioxide increases expression ISO RGD:731981 6480464 Arsenic Trioxide results in increased expression of KCNMA1 mRNA CTD PMID:20458559 dibutyl phthalate decreases expression ISO RGD:731982 6480464 Dibutyl Phthalate results in decreased expression of KCNMA1 mRNA CTD PMID:21266533 dioxygen decreases response to substance EXP 6480464 KCNMA1 mRNA alternative form results in decreased susceptibility to Oxygen deficiency CTD PMID:28090300 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of KCNMA1 mRNA alternative form, Oxygen deficiency results in increased expression of KCNMA1 protein alternative form CTD PMID:28090300 endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of KCNMA1 mRNA CTD PMID:29391264 endosulfan decreases expression ISO RGD:731981 6480464 Endosulfan results in decreased expression of KCNMA1 mRNA CTD PMID:30090376 ethanol increases activity ISO RGD:731982 6480464 Ethanol results in increased activity of KCNMA1 protein CTD PMID:16626657 ethanol increases expression ISO RGD:731982 6480464 Ethanol results in increased expression of KCNMA1 mRNA CTD PMID:30319688 ethanol affects splicing ISO RGD:731982 6480464 Ethanol affects the splicing of KCNMA1 mRNA CTD PMID:30319688 formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of KCNMA1 protein CTD PMID:30974163 fulvestrant multiple interactions EXP 6480464 fulvestrant inhibits the reaction [Estradiol results in decreased expression of KCNMA1 mRNA alternative form] more ... CTD PMID:16102753 glucose multiple interactions ISO RGD:731981 6480464 Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein] more ... CTD PMID:21413024 hydrogen peroxide affects response to substance EXP 6480464 KCNMA1 mRNA affects the susceptibility to Hydrogen Peroxide CTD PMID:19247476 indometacin multiple interactions ISO RGD:731982 6480464 [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 mRNA, [Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS protein co-treated with Indomethacin co-treated with rosiglitazone co-treated with Triiodothyronine] results in increased expression of KCNMA1 protein CTD PMID:27605626 indometacin multiple interactions ISO RGD:731981 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in decreased expression of KCNMA1 mRNA CTD PMID:28628672 lithocholic acid multiple interactions ISO RGD:731981 6480464 [KCNMB1 protein co-treated with KCNMA1 protein] results in increased susceptibility to Lithocholic Acid more ... CTD PMID:22123969 lithocholic acid increases response to substance ISO RGD:731981 6480464 KCNMA1 mRNA alternative form results in increased susceptibility to Lithocholic Acid CTD PMID:28090300 lithocholic acid multiple interactions EXP 6480464 Lithocholic Acid analog results in increased activity of [KCNMB1 protein co-treated with KCNMA1 protein], Lithocholic Acid results in increased activity of [KCNMB1 protein co-treated with KCNMA1 protein] CTD PMID:18650555 lithocholic acid increases response to substance EXP 6480464 KCNMA1 mRNA alternative form results in increased susceptibility to Lithocholic Acid, KCNMA1 protein results in increased susceptibility to Lithocholic Acid CTD PMID:18242174 , PMID:28090300 maneb multiple interactions ISO RGD:731982 6480464 [Paraquat co-treated with Maneb] affects the expression of KCNMA1 mRNA CTD PMID:22563483 methapyrilene decreases expression ISO RGD:731981 6480464 Methapyrilene results in decreased expression of KCNMA1 mRNA CTD PMID:31555880 methapyrilene affects methylation ISO RGD:731981 6480464 Methapyrilene affects the methylation of KCNMA1 intron CTD PMID:30157460 methotrexate increases expression ISO RGD:731981 6480464 Methotrexate results in increased expression of KCNMA1 mRNA CTD PMID:24449571 methoxychlor increases methylation EXP 6480464 Methoxychlor results in increased methylation of KCNMA1 gene CTD PMID:23303685 mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of KCNMA1 mRNA CTD PMID:25972201 nickel atom multiple interactions ISO RGD:731981 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of KCNMA1 mRNA] CTD PMID:14575637 nickel atom decreases expression ISO RGD:731981 6480464 Nickel results in decreased expression of KCNMA1 mRNA CTD PMID:24768652 , PMID:25583101 nickel atom affects expression ISO RGD:731981 6480464 Nickel affects the expression of KCNMA1 mRNA CTD PMID:14575637 nitrofen decreases expression EXP 6480464 nitrofen results in decreased expression of KCNMA1 mRNA, nitrofen results in decreased expression of KCNMA1 protein CTD PMID:15088113 nitrofen multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNMA1 mRNA], Dexamethasone inhibits the reaction [nitrofen results in decreased expression of KCNMA1 protein] CTD PMID:15088113 NS 1619 multiple interactions ISO RGD:731981 6480464 NS 1619 binds to and results in increased activity of KCNMA1 protein more ... CTD PMID:21413024 paclitaxel affects response to substance ISO RGD:731981 6480464 KCNMA1 protein affects the susceptibility to Paclitaxel CTD PMID:16217747 paraquat multiple interactions ISO RGD:731982 6480464 [Paraquat co-treated with Maneb] affects the expression of KCNMA1 mRNA CTD PMID:22563483 paraquat increases expression ISO RGD:731982 6480464 Paraquat results in increased expression of KCNMA1 mRNA CTD PMID:22563483 Paxilline affects response to substance EXP 6480464 KCNMA1 protein affects the susceptibility to paxilline CTD PMID:22226998 pentanal increases expression ISO RGD:731981 6480464 pentanal results in increased expression of KCNMA1 mRNA CTD PMID:26079696 pergolide decreases activity EXP 6480464 Pergolide results in decreased activity of KCNMA1 protein CTD PMID:16129789 phloretin affects response to substance EXP 6480464 KCNMA1 mRNA affects the susceptibility to Phloretin CTD PMID:19247476 piroxicam multiple interactions ISO RGD:731981 6480464 [Piroxicam co-treated with Cisplatin] results in increased expression of KCNMA1 mRNA CTD PMID:21858171 potassium atom increases transport ISO RGD:731982 6480464 KCNMA1 protein results in increased transport of Potassium CTD PMID:16020453 potassium atom affects transport EXP 6480464 KCNMA1 protein affects the transport of Potassium CTD PMID:22226998 progesterone multiple interactions ISO RGD:731981 6480464 [Estradiol co-treated with Progesterone] results in increased expression of KCNMA1 mRNA, Progesterone inhibits the reaction [Estradiol results in increased activity of KCNMA1 protein] CTD PMID:18068743 , PMID:20660070 progesterone increases expression ISO RGD:731981 6480464 Progesterone results in increased expression of KCNMA1 mRNA, Progesterone results in increased expression of KCNMA1 protein CTD PMID:21795739 progesterone decreases activity ISO RGD:731981 6480464 Progesterone results in decreased activity of KCNMA1 protein CTD PMID:18068743 progesterone increases expression EXP 6480464 Progesterone results in increased expression of KCNMA1 mRNA, Progesterone results in increased expression of KCNMA1 mRNA alternative form CTD PMID:16102753 propanal increases expression ISO RGD:731981 6480464 propionaldehyde results in increased expression of KCNMA1 mRNA CTD PMID:26079696 pyridaben increases expression ISO RGD:731982 6480464 pyridaben results in increased expression of KCNMA1 mRNA CTD PMID:22563483 rubidium atom affects activity ISO RGD:731982 6480464 Rubidium affects the activity of KCNMA1 protein CTD PMID:16636204 silicon dioxide increases expression ISO RGD:731981 6480464 Silicon Dioxide analog results in increased expression of KCNMA1 mRNA CTD PMID:25895662 sodium arsenite affects methylation ISO RGD:731981 6480464 sodium arsenite affects the methylation of KCNMA1 gene CTD PMID:28589171 sodium arsenite decreases expression ISO RGD:731981 6480464 sodium arsenite results in decreased expression of KCNMA1 mRNA CTD PMID:29301061 tamoxifen multiple interactions ISO RGD:731981 6480464 Tamoxifen inhibits the reaction [Glucose inhibits the reaction [[KCNMA1 protein binds to KCNMB1 protein] which results in decreased expression of BCL2 protein]], Tamoxifen inhibits the reaction [Glucose results in decreased activity of [KCNMA1 protein binds to KCNMB1 protein]] CTD PMID:21413024 tamoxifen multiple interactions EXP 6480464 [bexarotene co-treated with Tamoxifen] results in decreased expression of KCNMA1 mRNA CTD PMID:17630414 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of KCNMA1 mRNA, Carbon Tetrachloride results in increased expression of KCNMA1 protein CTD PMID:16644059 more ... tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of KCNMA1 mRNA CTD PMID:31150632 tetraethylammonium multiple interactions ISO RGD:731981 6480464 Tetraethylammonium inhibits the reaction [Estradiol results in increased activity of KCNMA1 protein] more ... CTD PMID:18068743 , PMID:21413024 thallium affects activity ISO RGD:731982 6480464 Thallium affects the activity of KCNMA1 protein CTD PMID:16636204 toluene decreases activity ISO RGD:731982 6480464 Toluene results in decreased activity of KCNMA1 protein CTD PMID:16626657 topotecan affects response to substance ISO RGD:731981 6480464 KCNMA1 protein affects the susceptibility to Topotecan CTD PMID:16217747 trichostatin A multiple interactions ISO RGD:731981 6480464 trichostatin A inhibits the reaction [Nickel affects the expression of KCNMA1 mRNA] CTD PMID:14575637 trichostatin A decreases expression ISO RGD:731981 6480464 trichostatin A results in decreased expression of KCNMA1 mRNA CTD PMID:24935251 valproic acid affects expression ISO RGD:731982 6480464 Valproic Acid affects the expression of KCNMA1 mRNA CTD PMID:17292431 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of KCNMA1 mRNA CTD PMID:29427782 vinclozolin affects expression EXP 6480464 vinclozolin affects the expression of KCNMA1 mRNA CTD PMID:19015723 XL147 multiple interactions ISO RGD:731982 6480464 [N-nitroso-tris-chloroethylurea co-treated with XL147] results in decreased expression of KCNMA1 mRNA CTD PMID:27935865
Biological Process adult walking behavior ISO RGD:731982 1624291 MGI:MGI:3050114 more ... RGD MGI:MGI:3047034 more ... aging IEP 10412028 RGD cell maturation ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3052624 , PMID:15328414) RGD MGI:MGI:3052624 , PMID:15328414 cellular potassium ion homeostasis ISO RGD:731981 1624291 (PMID:11245614) RGD PMID:11245614 cellular potassium ion homeostasis IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 chemical synaptic transmission ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3047034 , PMID:15194823) RGD MGI:MGI:3047034 , PMID:15194823 circadian rhythm ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3654773 , PMID:16845385) RGD MGI:MGI:3654773 , PMID:16845385 eye blink reflex ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3047034 , PMID:15194823) RGD MGI:MGI:3047034 , PMID:15194823 inner ear auditory receptor cell differentiation ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3052624 more ... RGD MGI:MGI:3052624 more ... locomotor rhythm ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3654773 , PMID:16845385) RGD MGI:MGI:3654773 , PMID:16845385 micturition ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3053479 , PMID:15184377) RGD MGI:MGI:3053479 , PMID:15184377 micturition ISO RGD:731981 1624291 (PMID:11641143) RGD PMID:11641143 negative regulation of cell volume ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3695228 , PMID:16873365) RGD MGI:MGI:3695228 , PMID:16873365 negative regulation of cell volume IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 negative regulation of cell volume ISO RGD:731981 1624291 (PMID:12388065) RGD PMID:12388065 negative regulation of small intestine smooth muscle contraction IMP 10412032 RGD neuromuscular process controlling balance ISO RGD:731982 1624291 MGI:MGI:3050114 more ... RGD MGI:MGI:3047034 more ... neuronal action potential ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3654773 , PMID:16845385) RGD MGI:MGI:3654773 , PMID:16845385 positive regulation of apoptotic process ISO RGD:731981 1624291 (PMID:11245614) RGD PMID:11245614 positive regulation of apoptotic process IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 positive regulation of blood vessel diameter IMP 10412027 RGD positive regulation of membrane hyperpolarization ISO RGD:14078396 1624291 (PMID:25139746) RGD PMID:25139746 positive regulation of neuron apoptotic process IMP 10412031 RGD potassium ion transmembrane transport IEA GO:0060072 1600115 GO_REF:0000108 GOC GO_REF:0000108 potassium ion transmembrane transport IEA UniProtKB-KW:KW-0631 1600115 GO_REF:0000043 UniProt GO_REF:0000043 potassium ion transport ISO RGD:731982 1624291 (MGI:MGI:1346192 more ... RGD MGI:MGI:1346192 more ... potassium ion transport ISO RGD:731981 1624291 (PMID:11245614), (PMID:12388065), (PMID:17706472), (PMID:18458941), (PMID:7573516), (PMID:7877450), (PMID:7993625) RGD PMID:11245614 more ... regulation of aldosterone metabolic process ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3693138 , PMID:17122062) RGD MGI:MGI:3693138 , PMID:17122062 regulation of blood vessel diameter IDA 1581588 RGD regulation of ion transmembrane transport IEA UniProtKB-KW:KW-0851 1600115 GO_REF:0000043 UniProt GO_REF:0000043 regulation of membrane potential ISO RGD:731981 1624291 (PMID:7877450), (PMID:7993625) RGD PMID:7877450 , PMID:7993625 regulation of membrane potential IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 regulation of membrane potential ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3047034 more ... RGD MGI:MGI:3047034 more ... regulation of presynaptic membrane potential IEA GO:0099507 1600115 GO_REF:0000108 GOC GO_REF:0000108 relaxation of vascular smooth muscle ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3695011 , PMID:15867178) RGD MGI:MGI:3695011 , PMID:15867178 relaxation of vascular smooth muscle ISO RGD:14078396 1624291 (PMID:25139746) RGD PMID:25139746 relaxation of vascular smooth muscle IBA MGI:MGI:99923 more ... 13792537 PMID:21873635 GO_Central response to calcium ion IDA 1581585 RGD response to calcium ion IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to calcium ion ISO RGD:731981 1624291 (PMID:12388065), (PMID:18458941) RGD PMID:12388065 , PMID:18458941 response to carbon monoxide ISO RGD:731981 1624291 (PMID:15528406), (PMID:18180950) RGD PMID:15528406 , PMID:18180950 response to carbon monoxide IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to corticosteroid IDA 1581581 RGD response to estrogen IDA 1581582 RGD response to hypoxia IDA 1581584 RGD response to hypoxia IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to hypoxia ISO RGD:731981 1624291 (PMID:15528406) RGD PMID:15528406 response to hypoxia ISO RGD:731982 1624291 (MGI:MGI:3611743, PMID:16306267) RGD MGI:MGI:3611743 , PMID:16306267 response to osmotic stress ISO RGD:731981 1624291 (PMID:10840032), (PMID:12388065) RGD PMID:10840032 , PMID:12388065 response to osmotic stress IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 response to pH IDA 1581586 RGD saliva secretion ISO RGD:731982 1624291 MGI:MGI:1277957 (MGI:MGI:3695228 , PMID:16873365) RGD MGI:MGI:3695228 , PMID:16873365 sensory perception of sound ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3052624 more ... RGD MGI:MGI:3052624 more ... sensory perception of sound NOT ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3697763 , PMID:17135251) RGD MGI:MGI:3697763 , PMID:17135251 smooth muscle contraction involved in micturition ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3612609 , PMID:15827347) RGD MGI:MGI:3612609 , PMID:15827347 smooth muscle contraction involved in micturition IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 smooth muscle contraction involved in micturition ISO RGD:731981 1624291 (PMID:11641143) RGD PMID:11641143 vasodilation ISO RGD:731982 1624291 MGI:MGI:3050114 (MGI:MGI:3695011 , PMID:15867178) RGD MGI:MGI:3695011 , PMID:15867178 Cellular Component apical plasma membrane ISO RGD:731982 1624291 (MGI:MGI:3697763, PMID:17135251) RGD MGI:MGI:3697763 , PMID:17135251 apical plasma membrane IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 apical plasma membrane ISO RGD:731981 1624291 (PMID:10840032) RGD PMID:10840032 caveola ISO RGD:731981 1624291 (PMID:15703204) RGD PMID:15703204 caveola IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 cytoplasm ISO RGD:731982 1624291 (MGI:MGI:2680842, PMID:12952984) RGD MGI:MGI:2680842 , PMID:12952984 dendrite IDA 1581583 RGD endoplasmic reticulum ISO RGD:731982 1624291 (MGI:MGI:3700594, PMID:17303127) RGD MGI:MGI:3700594 , PMID:17303127 endoplasmic reticulum membrane IEA UniProtKB-SubCell:SL-0097 1600115 GO_REF:0000044 UniProt GO_REF:0000044 external side of plasma membrane IDA 1581583 RGD external side of plasma membrane ISO RGD:731982 1624291 (MGI:MGI:3700594, PMID:17303127) RGD MGI:MGI:3700594 , PMID:17303127 glutamatergic synapse IDA 1581587 PMID:11739569 SynGO glutamatergic synapse EXP 1581587 PMID:11739569 SynGO integral component of membrane ISO RGD:731982 1624291 (MGI:MGI:2450799, PMID:12388098) RGD MGI:MGI:2450799 , PMID:12388098 integral component of membrane IEA UniProtKB-KW:KW-0812 1600115 GO_REF:0000043 UniProt GO_REF:0000043 integral component of membrane ISO RGD:731981 1624291 (PMID:11880513), (PMID:7573516), (PMID:7877450) RGD PMID:11880513 more ... integral component of presynaptic active zone membrane IDA 1581587 PMID:11739569 SynGO mitochondrion colocalizes_with IDA 10412029 RGD neuronal cell body IDA 1581583 RGD perinuclear region of cytoplasm IDA 1581589 RGD plasma membrane IDA 1581589 ; 7205477 RGD plasma membrane ISO RGD:731982 1624291 (MGI:MGI:1346192 more ... RGD MGI:MGI:1346192 more ... postsynaptic membrane ISO RGD:731982 1624291 (MGI:MGI:3052624, PMID:15328414) RGD MGI:MGI:3052624 , PMID:15328414 postsynaptic membrane IBA MGI:MGI:99923 , PANTHER:PTN000002875 13792537 PMID:21873635 GO_Central presynaptic active zone membrane IDA 1581587 RGD protein-containing complex IDA 7205477 RGD terminal bouton ISO RGD:731982 1624291 (MGI:MGI:3052624, PMID:15328414) RGD MGI:MGI:3052624 , PMID:15328414 voltage-gated potassium channel complex ISO RGD:731982 1624291 MGI:MGI:1334203 more ... RGD MGI:MGI:2450799 , PMID:12388098 voltage-gated potassium channel complex ISO RGD:731981 1624291 (PMID:7573516), (PMID:7877450), (PMID:7993625) RGD PMID:7573516 more ... voltage-gated potassium channel complex IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 Molecular Function actin binding ISO RGD:731981 1624291 (PMID:15703204) RGD PMID:15703204 actin binding IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 calcium-activated potassium channel activity IDA 633136 RGD calcium-activated potassium channel activity IBA FB:FBgn0003429 more ... 13792537 PMID:21873635 GO_Central calcium-activated potassium channel activity ISO RGD:731981 1624291 (PMID:11245614), (PMID:11880513), (PMID:17706472), (PMID:18458941), (PMID:7573516), (PMID:7877450), (PMID:7993625) RGD PMID:11245614 more ... calcium-activated potassium channel activity ISO RGD:731982 1624291 MGI:MGI:1334203 more ... RGD MGI:MGI:1346192 more ... identical protein binding IPI RGD:620715 1581583 homodimerization and homotetramerization RGD identical protein binding ISO RGD:731982 1624291 (MGI:MGI:3700594, PMID:17303127) RGD MGI:MGI:3700594 , PMID:17303127 identical protein binding ISO RGD:731981 1624291 UniProtKB:Q12791-5 (PMID:20574420) RGD PMID:20574420 large conductance calcium-activated potassium channel activity ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:2450799 more ... RGD MGI:MGI:2450799 more ... large conductance calcium-activated potassium channel activity IBA MGI:MGI:99923 more ... 13792537 PMID:21873635 GO_Central large conductance calcium-activated potassium channel activity IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107 large conductance calcium-activated potassium channel activity ISO RGD:731981 1624291 (PMID:15703204), (PMID:7993625) RGD PMID:15703204 , PMID:7993625 large conductance calcium-activated potassium channel activity IDA 7205477 RGD large conductance calcium-activated potassium channel activity IEA InterPro:IPR024939 1600115 GO_REF:0000002 InterPro GO_REF:0000002 ligand-gated ion channel activity involved in regulation of presynaptic membrane potential EXP 1581587 PMID:11739569 SynGO ligand-gated ion channel activity involved in regulation of presynaptic membrane potential IDA 1581587 PMID:11739569 SynGO metal ion binding IEA UniProtKB-KW:KW-0479 1600115 GO_REF:0000043 UniProt GO_REF:0000043 potassium channel activity ISO RGD:731982 1624291 MGI:MGI:1277957 more ... RGD MGI:MGI:3695228 more ... protein binding IPI RGD:1310533 1581583 RGD protein binding ISO RGD:14078396 1624291 UniProtKB:B3VP30 more ... RGD PMID:25139746 protein binding IPI UniProtKB:P02688 8554328 PMID:17610306 IntAct protein binding ISO RGD:731981 1624291 UniProtKB:P19440 more ... RGD PMID:10692449 more ... protein binding ISO RGD:731982 1624291 UniProtKB:O75791 more ... RGD MGI:MGI:3852248 more ... protein binding IPI RGD:3825 11059604 RGD protein-containing complex binding IPI RGD:620829 , RGD:2060 2313233 RGD voltage-gated potassium channel activity ISO RGD:731982 1624291 MGI:MGI:3053849 (MGI:MGI:3053479 more ... RGD MGI:MGI:3053479 more ... voltage-gated potassium channel activity ISO RGD:731981 1624291 (PMID:11880513), (PMID:12388065), (PMID:31152168), (PMID:7877450), (PMID:7993625) RGD PMID:11880513 more ... voltage-gated potassium channel activity IEA UniProtKB:Q12791 , ensembl:ENSP000002866281600115 GO_REF:0000107 Ensembl GO_REF:0000107
Gene-Chemical Interaction Annotations
