Ndrg2 (NDRG family member 2) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Ndrg2 (NDRG family member 2) Rattus norvegicus
Analyze
Symbol: Ndrg2
Name: NDRG family member 2
RGD ID: 621874
Description: Involved in postsynapse organization and signal transduction. Localizes to glutamatergic synapse. Orthologous to human NDRG2 (NDRG family member 2); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: antidepressant-related protein ADRG123; N-myc downstream regulated gene 2; N-myc downstream-regulated gene 2; NDRG1-related protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21524,600,981 - 24,609,621 (-)NCBI
Rnor_6.0 Ensembl1528,305,821 - 28,314,459 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01528,305,820 - 28,314,459 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01532,118,799 - 32,127,439 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,338,552 - 27,347,196 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11527,354,251 - 27,362,896 (-)NCBI
Celera1524,906,439 - 24,915,078 (-)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
antimony(0)  (ISO)
arsenite(3-)  (ISO)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
cerium trichloride  (ISO)
ciglitazone  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
cobalt dichloride  (EXP)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
corticosterone  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
cytarabine  (ISO)
D-glucose  (EXP,ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (EXP,ISO)
dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
genistein  (EXP,ISO)
glafenine  (EXP)
glucose  (EXP,ISO)
hexadecanoic acid  (ISO)
hydrogen peroxide  (ISO)
ketamine  (EXP)
L-ascorbic acid  (EXP)
L-ethionine  (EXP)
manganese(II) chloride  (EXP)
mechlorethamine  (ISO)
methapyrilene  (EXP)
methoxyacetic acid  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP,ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nickel dichloride  (EXP)
nickel sulfate  (ISO)
nimesulide  (EXP)
omeprazole  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
p-toluidine  (EXP)
paracetamol  (EXP,ISO)
perfluorononanoic acid  (ISO)
PhIP  (EXP)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (EXP,ISO)
propiconazole  (ISO)
Propiverine  (EXP)
quercetin  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (EXP,ISO)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone enanthate  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
thioacetamide  (EXP)
tipifarnib  (EXP)
titanium dioxide  (EXP,ISO)
topotecan  (EXP)
triclosan  (ISO)
trimellitic anhydride  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:14985363   PMID:14993068   PMID:15769300   PMID:16039777   PMID:16396499   PMID:16520977   PMID:17652085   PMID:19199708   PMID:19471968   PMID:19815093   PMID:20840522   PMID:21241684  
PMID:22110735   PMID:22610521   PMID:22871113   PMID:22926577   PMID:23376485   PMID:23463182   PMID:23540409   PMID:24343104   PMID:26414218   PMID:26631961   PMID:28670853   PMID:29476059  
PMID:32196570   PMID:32329820  


Genomics

Comparative Map Data
Ndrg2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21524,600,981 - 24,609,621 (-)NCBI
Rnor_6.0 Ensembl1528,305,821 - 28,314,459 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01528,305,820 - 28,314,459 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01532,118,799 - 32,127,439 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41527,338,552 - 27,347,196 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11527,354,251 - 27,362,896 (-)NCBI
Celera1524,906,439 - 24,915,078 (-)NCBICelera
Cytogenetic Map15p14NCBI
NDRG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1421,016,763 - 21,070,872 (-)EnsemblGRCh38hg38GRCh38
GRCh381421,016,763 - 21,070,872 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371421,484,922 - 21,539,031 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361420,554,762 - 20,563,775 (-)NCBINCBI36hg18NCBI36
Build 341420,554,762 - 20,563,104NCBI
Celera141,345,785 - 1,354,798 (-)NCBI
Cytogenetic Map14q11.2NCBI
HuRef141,606,057 - 1,614,869 (-)NCBIHuRef
CHM1_11421,487,031 - 21,540,818 (-)NCBICHM1_1
Ndrg2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391452,142,728 - 52,151,461 (-)NCBIGRCm39mm39
GRCm39 Ensembl1452,142,728 - 52,151,615 (-)Ensembl
GRCm381451,905,271 - 51,914,004 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1451,905,271 - 51,914,158 (-)EnsemblGRCm38mm10GRCm38
MGSCv371452,524,946 - 52,533,163 (-)NCBIGRCm37mm9NCBIm37
MGSCv361450,827,232 - 50,835,302 (-)NCBImm8
Celera1448,890,602 - 48,898,821 (-)NCBICelera
Cytogenetic Map14C2NCBI
Ndrg2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555501,767,911 - 1,780,635 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555501,771,514 - 1,778,693 (-)NCBIChiLan1.0ChiLan1.0
NDRG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11419,913,665 - 19,922,753 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1419,913,674 - 19,967,470 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0141,831,764 - 1,840,819 (-)NCBIMhudiblu_PPA_v0panPan3
NDRG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11518,106,651 - 18,115,026 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1518,106,654 - 18,113,970 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1518,592,191 - 18,609,584 (-)NCBI
ROS_Cfam_1.01518,367,496 - 18,384,905 (-)NCBI
UMICH_Zoey_3.11518,048,851 - 18,058,146 (-)NCBI
UNSW_CanFamBas_1.01518,104,845 - 18,122,209 (-)NCBI
UU_Cfam_GSD_1.01518,233,466 - 18,241,162 (-)NCBI
Ndrg2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864032,309,751 - 32,318,531 (-)NCBI
SpeTri2.0NW_004936880219,131 - 227,856 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDRG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl778,066,978 - 78,121,233 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1778,111,736 - 78,121,216 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
NDRG2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12921,490,219 - 21,499,194 (-)NCBI
ChlSab1.1 Ensembl2921,488,808 - 21,496,757 (-)Ensembl
Ndrg2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248257,008,475 - 7,017,422 (-)NCBI

Position Markers
RH129362  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01528,306,081 - 28,306,276NCBIRnor6.0
Rnor_5.01532,119,061 - 32,119,256UniSTSRnor5.0
RGSC_v3.41527,338,813 - 27,339,008UniSTSRGSC3.4
Celera1524,906,700 - 24,906,895UniSTS
Cytogenetic Map15p14UniSTS
RH130102  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01528,305,851 - 28,306,011NCBIRnor6.0
Rnor_5.01532,118,831 - 32,118,991UniSTSRnor5.0
RGSC_v3.41527,338,583 - 27,338,743UniSTSRGSC3.4
Celera1524,906,470 - 24,906,630UniSTS
Cytogenetic Map15p14UniSTS
RH140915  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01528,305,857 - 28,306,100NCBIRnor6.0
Rnor_5.01532,118,837 - 32,119,080UniSTSRnor5.0
RGSC_v3.41527,338,589 - 27,338,832UniSTSRGSC3.4
Celera1524,906,476 - 24,906,719UniSTS
Cytogenetic Map15p14UniSTS
Ndrg2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.01528,305,849 - 28,306,680NCBIRnor6.0
Rnor_5.01532,118,829 - 32,119,660UniSTSRnor5.0
RGSC_v3.41527,338,581 - 27,339,412UniSTSRGSC3.4
Celera1524,906,468 - 24,907,299UniSTS
Cytogenetic Map15p14UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15130597196Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15137708474Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15137708474Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15137708474Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15142844179Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15143521446Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15162301382Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15232787753535766Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15388113148881131Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)151071919155719191Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151549236072568189Rat
5685002Bss103Bone structure and strength QTL 1032.8tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)151582824233657761Rat
9590272Scort14Serum corticosterone level QTL 142.780.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)151698090761980907Rat
8694427Bw163Body weight QTL 1634.820.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)151698090761980907Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151724964162249641Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151724964162249641Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151724964162249641Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151809320881255430Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151851391388036354Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)152102134241082727Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)152102134252831189Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152377896946825072Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)1526381041106550657Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)1526381041106550657Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)1526381041106550657Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:411
Count of miRNA genes:169
Interacting mature miRNAs:199
Transcripts:ENSRNOT00000040540, ENSRNOT00000042055
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2 7
Medium 3 43 57 41 14 41 8 9 63 35 41 11 8
Low 5 4
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001270862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001270864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_133583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039092969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC094516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF334105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF334106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ426427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM045410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM057759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ213480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216465 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218864 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000263 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000040540   ⟹   ENSRNOP00000039619
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1528,305,821 - 28,314,459 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000042055   ⟹   ENSRNOP00000042949
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1528,305,821 - 28,314,459 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085897   ⟹   ENSRNOP00000072772
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1528,305,821 - 28,313,841 (-)Ensembl
RefSeq Acc Id: NM_001270862   ⟹   NP_001257791
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,600,982 - 24,609,621 (-)NCBI
Rnor_6.01528,305,820 - 28,314,459 (-)NCBI
Rnor_5.01532,118,799 - 32,127,439 (-)NCBI
Celera1524,906,439 - 24,915,078 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001270863   ⟹   NP_001257792
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,600,982 - 24,609,003 (-)NCBI
Rnor_6.01528,305,820 - 28,313,841 (-)NCBI
Rnor_5.01532,118,799 - 32,127,439 (-)NCBI
Celera1524,906,439 - 24,914,460 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001270864   ⟹   NP_001257793
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,600,982 - 24,609,003 (-)NCBI
Rnor_6.01528,305,820 - 28,313,841 (-)NCBI
Rnor_5.01532,118,799 - 32,127,439 (-)NCBI
Celera1524,906,439 - 24,914,460 (-)NCBI
Sequence:
RefSeq Acc Id: NM_133583   ⟹   NP_598267
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,600,982 - 24,609,621 (-)NCBI
Rnor_6.01528,305,820 - 28,314,459 (-)NCBI
Rnor_5.01532,118,799 - 32,127,439 (-)NCBI
RGSC_v3.41527,338,552 - 27,347,196 (-)RGD
Celera1524,906,439 - 24,915,078 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092969   ⟹   XP_038948897
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21524,600,981 - 24,608,628 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_598267   ⟸   NM_133583
- Peptide Label: isoform b
- UniProtKB: Q8VBU2 (UniProtKB/Swiss-Prot),   A0A0G2JSU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257791   ⟸   NM_001270862
- Peptide Label: isoform a
- UniProtKB: Q8VBU2 (UniProtKB/Swiss-Prot),   A0A0G2JSV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257793   ⟸   NM_001270864
- Peptide Label: isoform b
- UniProtKB: Q8VBU2 (UniProtKB/Swiss-Prot),   A0A0G2JSU4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001257792   ⟸   NM_001270863
- Peptide Label: isoform a
- UniProtKB: Q8VBU2 (UniProtKB/Swiss-Prot),   A0A0G2JSV0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000042949   ⟸   ENSRNOT00000042055
RefSeq Acc Id: ENSRNOP00000072772   ⟸   ENSRNOT00000085897
RefSeq Acc Id: ENSRNOP00000039619   ⟸   ENSRNOT00000040540
RefSeq Acc Id: XP_038948897   ⟸   XM_039092969
- Peptide Label: isoform X1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699632
Promoter ID:EPDNEW_R10156
Type:multiple initiation site
Name:Ndrg2_1
Description:NDRG family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10157  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01528,313,827 - 28,313,887EPDNEW
RGD ID:13699633
Promoter ID:EPDNEW_R10157
Type:initiation region
Name:Ndrg2_2
Description:NDRG family member 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10156  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01528,314,467 - 28,314,527EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621874 AgrOrtholog
Ensembl Genes ENSRNOG00000010389 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000039619 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000042949 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000072772 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000040540 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000042055 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000085897 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.1820 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro AB_hydrolase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDRG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDRG2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171114 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 171114 ENTREZGENE
PANTHER PTHR11034 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11034:SF17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ndr UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ndrg2 PhenoGen
Superfamily-SCOP SSF53474 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSU4 ENTREZGENE, UniProtKB/TrEMBL
  A0A0G2JSV0 ENTREZGENE, UniProtKB/TrEMBL
  NDRG2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q8VBW2 UniProtKB/Swiss-Prot
  Q8VI00 UniProtKB/Swiss-Prot
  Q8VI01 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Ndrg2  NDRG family member 2  Ndrg2  N-myc downstream regulated gene 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-07-29 Ndrg2  N-myc downstream regulated gene 2  Ndrg2  NDRG family member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-01-22 Ndrg2  NDRG family member 2  Ndrg2  N-myc downstream regulated gene 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-12-15 Ndrg2  N-myc downstream regulated gene 2  Ndrg2  NDRG family member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-09 Ndrg2  NDRG family member 2  Ndrg2  N-myc downstream regulated gene 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Ndrg2  N-myc downstream regulated gene 2  Ndrg2  N-myc downstream-regulated gene 2  Name updated 1299863 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_product member of the family of differentiation-related genes 625480