Ndst2 (N-deacetylase and N-sulfotransferase 2) - Rat Genome Database
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Gene: Ndst2 (N-deacetylase and N-sulfotransferase 2) Rattus norvegicus
Analyze
Symbol: Ndst2
Name: N-deacetylase and N-sulfotransferase 2
RGD ID: 1304700
Description: Predicted to have [heparan sulfate]-glucosamine N-sulfotransferase activity and deacetylase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process and regulation of angiotensin levels in blood. Predicted to localize to Golgi apparatus. Orthologous to human NDST2 (N-deacetylase and N-sulfotransferase 2); PARTICIPATES IN heparan sulfate biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2; N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2; N-deacetylase/N-sulfotransferase 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2153,563,358 - 3,573,801 (+)NCBI
Rnor_6.0 Ensembl153,996,048 - 4,006,491 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0153,995,797 - 4,006,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0153,726,893 - 3,737,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,788,239 - 3,798,682 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1153,792,088 - 3,798,551 (+)NCBI
Celera151,020,455 - 1,030,898 (-)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10466726   PMID:10466727   PMID:10639137   PMID:11087757   PMID:15173164  


Genomics

Comparative Map Data
Ndst2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2153,563,358 - 3,573,801 (+)NCBI
Rnor_6.0 Ensembl153,996,048 - 4,006,491 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0153,995,797 - 4,006,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0153,726,893 - 3,737,357 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4153,788,239 - 3,798,682 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1153,792,088 - 3,798,551 (+)NCBI
Celera151,020,455 - 1,030,898 (-)NCBICelera
Cytogenetic Map15p16NCBI
NDST2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1073,801,911 - 73,811,798 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1073,796,514 - 73,811,651 (-)EnsemblGRCh38hg38GRCh38
GRCh381073,801,916 - 73,811,820 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371075,561,674 - 75,571,578 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371075,561,669 - 75,571,589 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361075,231,675 - 75,241,348 (-)NCBINCBI36hg18NCBI36
Build 341075,231,674 - 75,241,348NCBI
Celera1068,844,842 - 68,854,762 (-)NCBI
Cytogenetic Map10q22.2NCBI
HuRef1069,556,745 - 69,566,664 (-)NCBIHuRef
CHM1_11075,843,450 - 75,853,374 (-)NCBICHM1_1
Ndst2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391420,773,798 - 20,784,638 (-)NCBIGRCm39mm39
GRCm381420,723,730 - 20,734,570 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1420,723,730 - 20,734,562 (-)EnsemblGRCm38mm10GRCm38
MGSCv371421,542,952 - 21,553,784 (-)NCBIGRCm37mm9NCBIm37
MGSCv361419,512,291 - 19,518,879 (-)NCBImm8
Celera1417,106,546 - 17,117,371 (-)NCBICelera
Cytogenetic Map14A3NCBI
Ndst2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543718,090,198 - 18,099,328 (+)NCBIChiLan1.0ChiLan1.0
NDST2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11072,997,205 - 73,006,645 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01070,324,842 - 70,335,169 (-)NCBIMhudiblu_PPA_v0panPan3
NDST2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl424,231,492 - 24,243,455 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1424,235,051 - 24,243,411 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ndst2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365215,336,658 - 5,346,704 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NDST2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11476,525,998 - 76,534,695 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21482,652,638 - 82,661,329 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NDST2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1957,561,349 - 57,574,145 (+)NCBI
Ndst2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247547,316,421 - 7,322,539 (-)NCBI

Position Markers
RH134514  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0153,760,247 - 3,760,444NCBIRnor6.0
Rnor_6.0154,005,986 - 4,006,183NCBIRnor6.0
Rnor_5.0153,736,852 - 3,737,049UniSTSRnor5.0
RGSC_v3.4153,798,177 - 3,798,374UniSTSRGSC3.4
Celera151,020,763 - 1,020,960UniSTS
RH 3.4 Map1547.9UniSTS
Cytogenetic Map15p16UniSTS
AA875438  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0153,760,771 - 3,760,995NCBIRnor6.0
Rnor_6.0154,006,510 - 4,006,734NCBIRnor6.0
Rnor_5.0153,737,376 - 3,737,600UniSTSRnor5.0
RGSC_v3.4153,798,701 - 3,798,925UniSTSRGSC3.4
Celera151,020,212 - 1,020,436UniSTS
RH 3.4 Map1566.8UniSTS
Cytogenetic Map15p16UniSTS
GDB:642165  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0153,760,520 - 3,760,594NCBIRnor6.0
Rnor_6.0154,006,259 - 4,006,333NCBIRnor6.0
Rnor_5.0153,737,125 - 3,737,199UniSTSRnor5.0
RGSC_v3.4153,798,450 - 3,798,524UniSTSRGSC3.4
Celera151,020,613 - 1,020,687UniSTS
Cytogenetic Map15p16UniSTS
Ndst2  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0153,758,945 - 3,759,291NCBIRnor6.0
Rnor_6.0154,004,684 - 4,005,030NCBIRnor6.0
Rnor_5.0153,735,550 - 3,735,896UniSTSRnor5.0
Celera151,021,916 - 1,022,262UniSTS
Cytogenetic Map15p16UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300142Bp191Blood pressure QTL 1913.14arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)15112800829Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15130597196Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15137708474Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15137708474Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15137708474Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15142844179Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15143521446Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15162301382Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15110589015828368Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)colorectal tumor number (CMO:0001794)15232787726288802Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15232787726288802Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15232787753535766Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15388113148881131Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:74
Count of miRNA genes:58
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000035100
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 3 24 35 19 19 19 1 3 67 27 40 11 1
Below cutoff 19 22 22 22 7 8 7 8 1 7

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000078653   ⟹   ENSRNOP00000073946
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl153,996,048 - 4,006,491 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000088252   ⟹   ENSRNOP00000073437
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl153,996,328 - 4,006,354 (+)Ensembl
RefSeq Acc Id: NM_001105740   ⟹   NP_001099210
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2153,563,358 - 3,573,801 (+)NCBI
Rnor_6.0153,996,048 - 4,006,491 (+)NCBI
Rnor_5.0153,726,893 - 3,737,357 (+)NCBI
RGSC_v3.4153,788,239 - 3,798,682 (+)RGD
Celera151,020,455 - 1,030,898 (-)RGD
Sequence:
RefSeq Acc Id: XM_008770476   ⟹   XP_008768698
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0153,995,797 - 4,006,355 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770477   ⟹   XP_008768699
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2153,563,567 - 3,573,665 (+)NCBI
Rnor_6.0153,995,797 - 4,006,355 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770478   ⟹   XP_008768700
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0153,995,797 - 4,005,177 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770479   ⟹   XP_008768701
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2153,563,567 - 3,572,619 (+)NCBI
Rnor_6.0153,995,797 - 4,005,258 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770480   ⟹   XP_008768702
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0154,001,211 - 4,006,355 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039092946   ⟹   XP_038948874
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2153,563,567 - 3,573,665 (+)NCBI
RefSeq Acc Id: XM_039092947   ⟹   XP_038948875
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2153,563,567 - 3,573,665 (+)NCBI
RefSeq Acc Id: XR_005493682
RefSeq Status:
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2153,563,567 - 3,571,989 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_001099210   ⟸   NM_001105740
- UniProtKB: D3ZD62 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768698   ⟸   XM_008770476
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008768699   ⟸   XM_008770477
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008768701   ⟸   XM_008770479
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_008768700   ⟸   XM_008770478
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_008768702   ⟸   XM_008770480
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: ENSRNOP00000073437   ⟸   ENSRNOT00000088252
RefSeq Acc Id: ENSRNOP00000073946   ⟸   ENSRNOT00000078653
RefSeq Acc Id: XP_038948875   ⟸   XM_039092947
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038948874   ⟸   XM_039092946
- Peptide Label: isoform X1
Protein Domains
HSNSD   Sulfotransfer_1

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699559
Promoter ID:EPDNEW_R10080
Type:single initiation site
Name:NEWGENE_1304700_2
Description:N-deacetylase/N-sulfotransferase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10081  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0153,996,042 - 3,996,102EPDNEW
RGD ID:13699570
Promoter ID:EPDNEW_R10081
Type:multiple initiation site
Name:NEWGENE_1304700_1
Description:N-deacetylase/N-sulfotransferase 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R10080  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0153,996,268 - 3,996,328EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1304700 AgrOrtholog
Ensembl Genes ENSRNOG00000027171 UniProtKB/TrEMBL
  ENSRNOG00000057755 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000031692 UniProtKB/TrEMBL
  ENSRNOP00000073437 UniProtKB/TrEMBL
  ENSRNOP00000073946 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035100 UniProtKB/TrEMBL
  ENSRNOT00000078653 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000088252 UniProtKB/TrEMBL
InterPro Heparan_SO4_deacetylase UniProtKB/TrEMBL
  NST/OST UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Sulfotransferase_dom UniProtKB/TrEMBL
KEGG Report rno:103690051 UniProtKB/TrEMBL
  rno:114002 UniProtKB/TrEMBL
NCBI Gene 114002 ENTREZGENE
PANTHER PTHR10605 UniProtKB/TrEMBL
Pfam HSNSD UniProtKB/TrEMBL
  Sulfotransfer_1 UniProtKB/TrEMBL
PhenoGen Ndst2 PhenoGen
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
UniProt D3ZD62 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-21 Ndst2  N-deacetylase and N-sulfotransferase 2  Ndst2  N-deacetylase/N-sulfotransferase 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-02-03 Ndst2  N-deacetylase/N-sulfotransferase 2  Ndst2  N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Ndst2  N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2   Ndst2_predicted  N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Ndst2_predicted  N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED