Gng2 (G protein subunit gamma 2) - Rat Genome Database
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Gene: Gng2 (G protein subunit gamma 2) Rattus norvegicus
Analyze
Symbol: Gng2
Name: G protein subunit gamma 2
RGD ID: 69268
Description: Predicted to have G-protein beta-subunit binding activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; positive regulation of epithelial cell migration; and positive regulation of lamellipodium morphogenesis. Localizes to heterotrimeric G-protein complex. Orthologous to human GNG2 (G protein subunit gamma 2); PARTICIPATES IN eicosanoid signaling pathway; Hedgehog signaling pathway; chemokine mediated signaling pathway; INTERACTS WITH 6-propyl-2-thiouracil; acetamide; bis(2-ethylhexyl) phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: guanine nucleotide binding protein (G protein) gamma 2 subunit; guanine nucleotide binding protein (G protein),; guanine nucleotide binding protein (G protein), gamma 2; guanine nucleotide binding protein (G protein), gamma 2 subunit; guanine nucleotide binding protein, gamma 2; guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2154,316,038 - 4,416,918 (+)NCBI
Rnor_6.0 Ensembl154,850,122 - 4,853,555 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0154,748,242 - 4,853,555 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0158,845,752 - 8,944,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera15191,251 - 288,803 (-)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:12606627   PMID:14712229   PMID:18054784   PMID:19168664   PMID:20458337   PMID:21633701   PMID:23376485  


Genomics

Comparative Map Data
Gng2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2154,316,038 - 4,416,918 (+)NCBI
Rnor_6.0 Ensembl154,850,122 - 4,853,555 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0154,748,242 - 4,853,555 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0158,845,752 - 8,944,463 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera15191,251 - 288,803 (-)NCBICelera
Cytogenetic Map15p16NCBI
GNG2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1451,826,195 - 51,979,342 (+)EnsemblGRCh38hg38GRCh38
GRCh381451,826,174 - 51,969,800 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371452,327,330 - 52,436,513 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361451,396,800 - 51,506,268 (+)NCBINCBI36hg18NCBI36
Build 341451,414,059 - 51,506,263NCBI
Celera1432,194,027 - 32,303,511 (+)NCBI
Cytogenetic Map14q22.1NCBI
HuRef1432,487,496 - 32,597,199 (+)NCBIHuRef
CHM1_11452,265,402 - 52,374,976 (+)NCBICHM1_1
Gng2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391419,922,626 - 20,027,893 (-)NCBIGRCm39mm39
GRCm39 Ensembl1419,922,627 - 20,027,695 (-)Ensembl
GRCm381419,872,558 - 19,977,825 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1419,872,559 - 19,977,627 (-)EnsemblGRCm38mm10GRCm38
MGSCv371420,691,781 - 20,796,471 (-)NCBIGRCm37mm9NCBIm37
MGSCv361418,663,255 - 18,767,945 (-)NCBImm8
Celera1416,255,643 - 16,361,179 (-)NCBICelera
Cytogenetic Map14A3NCBI
cM Map1411.17NCBI
Gng2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540911,075,455 - 11,088,455 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540911,075,455 - 11,178,993 (-)NCBIChiLan1.0ChiLan1.0
GNG2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11450,732,106 - 50,854,596 (+)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01432,460,027 - 32,569,359 (+)NCBIMhudiblu_PPA_v0panPan3
GNG2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1828,080,699 - 28,194,464 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl828,049,195 - 28,191,358 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha827,833,479 - 27,947,171 (+)NCBI
ROS_Cfam_1.0828,258,413 - 28,372,188 (+)NCBI
UMICH_Zoey_3.1827,927,704 - 28,041,498 (+)NCBI
UNSW_CanFamBas_1.0827,988,682 - 28,102,533 (+)NCBI
UU_Cfam_GSD_1.0828,335,664 - 28,449,250 (+)NCBI
Gng2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864060,308,633 - 60,416,144 (+)NCBI
SpeTri2.0NW_00493649513,775,555 - 13,883,042 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNG2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11181,485,257 - 181,651,972 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21201,794,957 - 201,826,239 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNG2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12428,935,885 - 29,069,741 (+)NCBI
ChlSab1.1 Ensembl2428,950,031 - 29,066,892 (+)Ensembl
Gng2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473117,081,259 - 17,185,073 (-)NCBI

Position Markers
D15Rat77  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0154,805,951 - 4,806,183NCBIRnor6.0
Rnor_5.0158,901,880 - 8,902,112UniSTSRnor5.0
Celera15231,099 - 231,331UniSTS
RH 3.4 Map1573.2RGD
RH 3.4 Map1573.2UniSTS
SHRSP x BN Map152.7498RGD
SHRSP x BN Map152.7498UniSTS
BE120130  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0154,852,015 - 4,852,170NCBIRnor6.0
Rnor_5.0158,942,923 - 8,943,078UniSTSRnor5.0
Celera15192,636 - 192,791UniSTS
RH 3.4 Map1569.5UniSTS
RH134043  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0154,850,357 - 4,850,559NCBIRnor6.0
Rnor_5.0158,941,265 - 8,941,467UniSTSRnor5.0
Celera15194,244 - 194,446UniSTS
RH 3.4 Map1570.0UniSTS
RH135076  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0154,853,331 - 4,853,517NCBIRnor6.0
Rnor_5.0158,944,239 - 8,944,425UniSTSRnor5.0
Celera15191,289 - 191,475UniSTS
RH 3.4 Map1569.5UniSTS
RH141577  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0154,850,691 - 4,850,909NCBIRnor6.0
Rnor_5.0158,941,599 - 8,941,817UniSTSRnor5.0
Celera15193,897 - 194,115UniSTS
RH 3.4 Map1569.6UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300142Bp191Blood pressure QTL 1913.14arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)15112800829Rat
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15130597196Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15137708474Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15137708474Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15137708474Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15142844179Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15143521446Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15162301382Rat
5684946Bss98Bone structure and strength QTL 983.90.0026tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)15110589015828368Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)colorectal tumor number (CMO:0001794)15232787726288802Rat
1641913Colcr2Colorectal carcinoma resistance QTL 26.570.0197intestine integrity trait (VT:0010554)poorly differentiated malignant colorectal tumor number (CMO:0002076)15232787726288802Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15232787753535766Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)15388113148881131Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:93
Count of miRNA genes:84
Interacting mature miRNAs:88
Transcripts:ENSRNOT00000071133
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 28 13 6 18 6 74 18 32 8
Low 1 15 44 35 1 35 8 10 17 9 3 8
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001257349 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_031754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093681 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039093682 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF022087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB609817 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ120495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ120496 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM112505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214279 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230460 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000071133   ⟹   ENSRNOP00000066927
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl154,850,122 - 4,853,555 (+)Ensembl
RefSeq Acc Id: NM_001257349   ⟹   NP_001244278
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2154,316,636 - 4,416,918 (+)NCBI
Rnor_6.0154,748,635 - 4,853,555 (+)NCBI
Rnor_5.0158,845,752 - 8,944,463 (+)NCBI
Celera15191,251 - 288,410 (-)NCBI
Sequence:
RefSeq Acc Id: NM_031754   ⟹   NP_113942
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2154,316,243 - 4,416,918 (+)NCBI
Rnor_6.0154,748,242 - 4,853,555 (+)NCBI
Rnor_5.0158,845,752 - 8,944,463 (+)NCBI
Celera15191,251 - 288,803 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039093680   ⟹   XP_038949608
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2154,316,038 - 4,416,918 (+)NCBI
RefSeq Acc Id: XM_039093681   ⟹   XP_038949609
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2154,316,068 - 4,416,918 (+)NCBI
RefSeq Acc Id: XM_039093682   ⟹   XP_038949610
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2154,316,318 - 4,416,918 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_113942   ⟸   NM_031754
- Sequence:
RefSeq Acc Id: NP_001244278   ⟸   NM_001257349
- Sequence:
RefSeq Acc Id: ENSRNOP00000066927   ⟸   ENSRNOT00000071133
RefSeq Acc Id: XP_038949608   ⟸   XM_039093680
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949609   ⟸   XM_039093681
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949610   ⟸   XM_039093682
- Peptide Label: isoform X1
Protein Domains
G protein gamma

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:69268 AgrOrtholog
Ensembl Genes ENSRNOG00000048980 Ensembl, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000066927 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000071133 UniProtKB/TrEMBL
Gene3D-CATH 4.10.260.10 UniProtKB/TrEMBL
InterPro G-protein_gamma-like_dom UniProtKB/TrEMBL
  GGL_sf UniProtKB/TrEMBL
  Gprotein-gamma UniProtKB/TrEMBL
NCBI Gene 80850 ENTREZGENE
PANTHER PTHR13809 UniProtKB/TrEMBL
Pfam G-gamma UniProtKB/TrEMBL
PhenoGen Gng2 PhenoGen
PRINTS GPROTEING UniProtKB/TrEMBL
PROSITE G_PROTEIN_GAMMA UniProtKB/TrEMBL
SMART GGL UniProtKB/TrEMBL
Superfamily-SCOP SSF48670 UniProtKB/TrEMBL
UniProt M0RBJ0_RAT UniProtKB/TrEMBL
  Q45QK6_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-15 Gng2  G protein subunit gamma 2  Gng2  guanine nucleotide binding protein (G protein), gamma 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-18 Gng2  guanine nucleotide binding protein (G protein), gamma 2  Gng2  guanine nucleotide binding protein, gamma 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-06-10 Gng2  guanine nucleotide binding protein, gamma 2      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_expression highly expressed in limbic system 632972
gene_expression coexpressed with beta4 subunit mRNAs in layer VI of the occipital cortex 632972