Oxsm (3-oxoacyl-ACP synthase, mitochondrial)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Oxsm (3-oxoacyl-ACP synthase, mitochondrial) Rattus norvegicus

Analyze

Symbol:

Oxsm

Name:

3-oxoacyl-ACP synthase, mitochondrial

RGD ID:

1311092

Description:

Predicted to enable 3-oxoacyl-[acyl-carrier-protein] synthase activity. Predicted to be involved in acyl-CoA metabolic process; medium-chain fatty acid biosynthetic process; and short-chain fatty acid biosynthetic process. Predicted to be located in cytosol. Predicted to be active in mitochondrion. Orthologous to human OXSM (3-oxoacyl-ACP synthase, mitochondrial); PARTICIPATES IN fatty acid biosynthetic pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; LOC289934; RGD1311092; similar to hypothetical protein FLJ20604

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	OXSM (3-oxoacyl-ACP synthase, mitochondrial)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther
Mus musculus (house mouse):	Oxsm (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Oxsm (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	OXSM (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	OXSM (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Oxsm (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	OXSM (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	OXSM (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Oxsm (3-oxoacyl-ACP synthase, mitochondrial)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	MGST3 (microsomal glutathione S-transferase 3)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Oxsm (3-oxoacyl-ACP synthase, mitochondrial)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	OXSM (3-oxoacyl-ACP synthase, mitochondrial)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	oxsm (3-oxoacyl-ACP synthase, mitochondrial)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG12170	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	CEM1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	F10G8.9	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	oxsm	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	9,210,443 - 9,215,852 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	9,210,547 - 9,214,558 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	11,353,346 - 11,356,828 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	12,266,135 - 12,269,617 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	10,566,610 - 10,570,092 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	10,462,380 - 10,466,496 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	10,462,106 - 10,466,496 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	14,507,711 - 14,511,770 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	10,761,610 - 10,765,356 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	10,762,673 - 10,765,356 (+)	NCBI
Celera	15	9,249,455 - 9,252,948 (+)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

1,2-dimethylhydrazine (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2-hydroxypropanoic acid (ISO)

aflatoxin B1 (ISO)

amiodarone (ISO)

benzene (ISO)

bisphenol A (EXP)

bisphenol F (ISO)

cadmium dichloride (ISO)

carbamazepine (ISO)

CGP 52608 (ISO)

chloroacetaldehyde (ISO)

chlorpyrifos (ISO)

cidofovir anhydrous (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

dicrotophos (ISO)

dioxygen (ISO)

doxorubicin (ISO)

finasteride (EXP)

flutamide (EXP)

formaldehyde (ISO)

gentamycin (EXP)

paracetamol (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

rac-lactic acid (ISO)

senecionine (ISO)

sodium fluoride (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

acyl-CoA metabolic process (ISO)

fatty acid biosynthetic process (IBA)

medium-chain fatty acid biosynthetic process (ISO)

short-chain fatty acid biosynthetic process (ISO)

Cellular Component

cytosol (IEA,ISO)

mitochondrion (IBA,ISO)

Molecular Function

3-oxoacyl-[acyl-carrier-protein] synthase activity (IBA,ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

fatty acid biosynthetic pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15668256	PMID:18614015

Genomics

Comparative Map Data

Oxsm
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	9,210,443 - 9,215,852 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	9,210,547 - 9,214,558 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	11,353,346 - 11,356,828 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	15	12,266,135 - 12,269,617 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	15	10,566,610 - 10,570,092 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	15	10,462,380 - 10,466,496 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	10,462,106 - 10,466,496 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	14,507,711 - 14,511,770 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	10,761,610 - 10,765,356 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	10,762,673 - 10,765,356 (+)	NCBI
Celera	15	9,249,455 - 9,252,948 (+)	NCBI		Celera
Cytogenetic Map	15	p16	NCBI

OXSM
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	25,790,090 - 25,794,531 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	25,782,917 - 25,794,534 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	25,831,581 - 25,836,022 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	25,806,575 - 25,811,029 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	3	25,768,436 - 25,772,898 (+)	NCBI		Celera
Cytogenetic Map	3	p24.2	NCBI
HuRef	3	25,776,553 - 25,781,015 (+)	NCBI		HuRef
CHM1_1	3	25,781,541 - 25,786,000 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	25,786,612 - 25,797,297 (+)	NCBI		T2T-CHM13v2.0

Oxsm
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	6,219,955 - 6,231,111 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	6,219,955 - 6,231,111 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	16,238,652 - 16,249,808 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	16,238,652 - 16,249,808 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	17,071,173 - 17,082,322 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	15,031,926 - 15,043,075 (-)	NCBI		MGSCv36	mm8
Celera	14	11,933,669 - 11,944,766 (-)	NCBI		Celera
Cytogenetic Map	14	A1	NCBI
cM Map	14	7.08	NCBI

Oxsm
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955430	17,653,438 - 17,658,171 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955430	17,644,800 - 17,661,097 (+)	NCBI	ChiLan1.0	ChiLan1.0

OXSM
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	3	25,747,760 - 25,761,286 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	25,683,801 - 25,697,227 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	26,015,343 - 26,026,222 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	26,021,806 - 26,026,222 (+)	Ensembl	panpan1.1		panPan2

OXSM
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	18,034,532 - 18,045,630 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	18,034,526 - 18,045,217 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	18,032,163 - 18,043,226 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	18,337,417 - 18,348,700 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	18,337,423 - 18,342,365 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	18,156,214 - 18,167,276 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	18,259,330 - 18,270,399 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	18,373,009 - 18,384,089 (-)	NCBI		UU_Cfam_GSD_1.0

Oxsm
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	184,159,101 - 184,166,433 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936473	17,298,777 - 17,305,007 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936473	17,298,641 - 17,302,954 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

OXSM
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	12,685,974 - 12,695,244 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	12,685,893 - 12,692,148 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	14,291,830 - 14,296,658 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

OXSM
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	70,447,061 - 70,460,690 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	70,457,228 - 70,460,650 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	43,587,980 - 43,599,795 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Oxsm
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624788	3,714,360 - 3,718,678 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624788	3,701,751 - 3,721,743 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Oxsm
58 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	305
Count of miRNA genes:	169
Interacting mature miRNAs:	192
Transcripts:	ENSRNOT00000008035
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	29912054	Rat
8552920	Pigfal8	Plasma insulin-like growth factor 1 level QTL 8	3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	15	1	34723002	Rat
8694361	Abfw6	Abdominal fat weight QTL 6	10.2	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	15	1	34723002	Rat
9589149	Insul29	Insulin level QTL 29	9.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	15	1	34723002	Rat
731170	Pur3	Proteinuria QTL 3	2.3	0.0005	urine protein amount (VT:0005160)	urine protein excretion rate (CMO:0000759)	15	1	41686771	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	42356671	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	306329	45306329	Rat
5684946	Bss98	Bone structure and strength QTL 98	3.9	0.0026	tibia strength trait (VT:1000284)	tibia ultimate force (CMO:0001734)	15	1058250	14481294	Rat
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	colorectal tumor number (CMO:0001794)	15	2266368	22711984	Rat
1641913	Colcr2	Colorectal carcinoma resistance QTL 2	6.57	0.0197	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	15	2266368	22711984	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat

Markers in Region

RH133244

Rat Assembly	Chr	Position (strand)	Source	JBrowse
RH 3.4 Map	15	110.3	UniSTS
Cytogenetic Map	15	p16	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		5							14	12	5
Low	3	38	57	41	19	41	8	11	60	23	36	11	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001100508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006251711	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC090025	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000260	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000008035 ⟹ ENSRNOP00000008035

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	9,210,547 - 9,214,558 (+)	Ensembl
Rnor_6.0 Ensembl	15	10,462,749 - 10,466,496 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000078249 ⟹ ENSRNOP00000074133

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	15	10,462,106 - 10,466,021 (+)	Ensembl

RefSeq Acc Id:

NM_001100508 ⟹ NP_001093978

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	9,210,883 - 9,214,629 (+)	NCBI
Rnor_6.0	15	10,462,749 - 10,466,496 (+)	NCBI
Rnor_5.0	15	14,507,711 - 14,511,770 (+)	NCBI
RGSC_v3.4	15	10,761,610 - 10,765,356 (+)	RGD
Celera	15	9,249,455 - 9,252,948 (+)	RGD

Sequence:

show sequence

GAAGGATGCCCCCTGCAGGGTGGGGTGGCTTTGTGAAATCCAGCGAACTTGCTGTCAGTTGACA
GTCTGAGGGACCTCATAGATTACAAATAAAAGTTAAGTCCAAGCGAGTGTTGCATTTTTCTGTG
GCTTTTAGCACATGACCTCAAGCACACCTAGGGTGTGTATGTAAGATCCTTCGATTGTTTAAAC
AAAAGTTGCTGTCTCTTGTGATCTGTTCCAGGAATGTGTTTCTGATCTTCTGAATTTCAACCAT
GTTGTCAAAGTGCTTGCAACATTTTCTAAAAGCCCATCTGTATCCAGCATCATATTGTTGGTTA
ATAAGCAAGCACAAGTTTTCTGGAAGTGTGCCAGCAGCCGGGTCGCGCAGGCGAGTTGTCATCA
CAGGCATTGGACTAGTGACACCACTTGGCGTTGGGACTCAACTAGTTTGGGATCGGCTTCTCCG
AGGAGAAAGTGGAATTGTTTCTGTAGTTGGTGATGAGTACAAGAGTATTCCTTGCAGTGTAGCT
GCTTTTGTACCAAGAGGTTCAGATAAAGGTCAGTTTAATGAACAAAACTTTGTGTCCAAATCAG
ATGCCAAGTCCATGTCCTCTCCCACCATCATGGCGGTCGGAGCAGCAGAGTTGGCCCTGAAAGA
CTCCGGCTGGTATCCAAAACTAGAAGCAGATCAGGTGGCTACTGGCGTTGCCATTGGCATGGGC
ATGGTTCCTCTGGAAGTTGTTTCTGAAACTGCTTTAATGTTTCAAACCAAAGGTTATAGTAAAG
TAAGCCCATTCTTTGTCCCTAAGATTCTGATCAATATGGCTGCAGGCCAGGTCAGCATTCGCTA
CAAACTCAAAGGCCCCAATCATTCAGTGTCTACAGCCTGTACCACGGGTGCACATGCTGTGGGA
GACTCTTTTAGACTTATAGCCCATGGTGACGCAGATGTGATGGTGGCTGGAGGCACAGACTCTT
GTATTAGTCCGTTATCTCTCGCTGGGTTTTCCAGAGCCCGGGCTCTAAGCACGAACCCAGATCC
TAAGCTGGCCTGCCGACCATTTCATCCAGAAAGAGATGGTTTTGTCATGGGTGAGGGAGCTGCT
GTACTGGTGCTAGAAGAACATGAACATGCTGTTCAGAGAGGAGCCCGGATCTACGCAGAAGTTT
TGGGTTATGGACTCTCAGGTGATGCTGGTCACATAACTGCCCCCGATCCTGAAGGAGAAGGTGC
TTTAAGATGCATGGCTGCTGCTGTAAAAGATGCAGGCGTATCACCTGATCAGATATCCTATGTC
AACGCACATGCCACCTCCACACCACTGGGTGACGCTGCTGAGAACAGAGCCATCAAGAGGCTCT
TTAGGGACCATGCTCGTGCCCTCGCCATATCCTCCACAAAGGGAGCCACGGGGCATCTTCTGGG
AGCTGCAGGGGCAGTCGAGGCAGCTTTCACTGCACTGGCTTGTTACCATCACAAACTACCGCCA
ACTTTAAACCTGGATTGTACAGAGGCAGAATTTGATCTCAATTATGTTCCACTGGAGGCACAGG
AATGGAAAACCGAGGGTCGATGTATTGGACTCACCAATTCCTTCGGGTTTGGTGGTACTAATGC
GACACTTTGTATTGCTGGCATGTAAGCTTTGGCTTTCAATAGTCATAAATGTATAAATAGTATG
CACATAAATGTCTTATCAGTGCCCAGGTGACTCTAGCCTACTTGGTATTTGTACAGTTCTTTGC
TAGTGAACAGGCTACCTAGTACTTGTCGGTATTTTATAGCATCTTGGTGTCTCCTGTGAGATTT
CAGTGGCAACTGTGACAACTAGAAATGTCTCTGGAGGACAGGATAGCCTGCACACAGAACTACT
GATTTATATTTTTCTAACGCACTATTTCACCCATCCCTGTCCTTTTTAGATATTTATTTAGAGA
CTAGCTCCTCTGAGCAAGGCTGTGTTGCTTCATGGTGTAACTCTAGGGGCACCACTGTCATACA
GCATATAGGGAGGAATGTAATACAAGTAGGAGTATGCATCATCAGGCAGCATCCTTTGAGGACA
ACTGTCAGTCAATTATGGCCTAGTCACCCCTGACCTGTGTAGGTCTCCTCAGTGGATTTTCCCC
CAAGCTTTCATTTCTCTGAAGGAGGAAGTGAAGCTGATTTGGCATTTTTCTTGTCTTTTCTCAT
TTGTCCTTCCTTCCTTCCTTCCTTTCTCCTCCTCTTCTTCTCCTTCCTCCTCTTCTTCCTCCCC
TTTCTCCTCTTCCTCCCCTCCCCCTTTCTCCTCTTCCCCTTCCTCCTCTTCTTCTCCTTCCTCC
TCTTCTTCCTCCCCTTTCTCCTCTTCCTCCCCTTCCTCCTCTTCCCCTTTCTCCTCTTCCCCTT
CCTCTTCCTCCCCTTCCTCCTCCTCTTCCTCCCCTTCCTCCTCTTCCTCCCCTTCCTCCTCCTC
TTCCTCCCCTTCCTCCTCTTCCTCCCCTTCCTCCTCCTCTTCCTCCCCTTCCTCCTCTTCCTCC
CCTTCCTCCTCCCCTCCTCCCCTTCCTCCCCTTCCTCCTCCTCTTCCTCCTCCCCTCCTCCTCT
TCCTCTTCCTCCCCCTCTTCCTCCTCTTCCTCTTCTTTCTCCTCTTCCTCCTCCTCTTCCTCCT
CTACTTCTTTGAGACTGGGTTTCTCTTGGAACTCATTCTATAAACCCTGGCTGGCCTTGAACTC
AACAAAGATCTGTTTGCCTCTGCCTCCCAAGTGCTACTATTAAAGGTGTACACCAC

hide sequence

RefSeq Acc Id:

XM_006251711 ⟹ XP_006251773

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	9,210,463 - 9,215,852 (+)	NCBI
Rnor_6.0	15	10,462,380 - 10,466,496 (+)	NCBI
Rnor_5.0	15	14,507,711 - 14,511,770 (+)	NCBI

Sequence:

show sequence

GCCAGTCTCCGGGCGGAAGAAACGCTGCGCAGCAGACCAGCGTGCGCATGCGCACTCGGTGAGC
GCCCGCAAAGGCTTGTTTCAGGAATGTGTTTCTGATCTTCTGAATTTCAACCATGTTGTCAAAG
TGCTTGCAACATTTTCTAAAAGCCCATCTGTATCCAGCATCATATTGTTGGTTAATAAGCAAGC
ACAAGTTTTCTGGAAGTGTGCCAGCAGCCGGGTCGCGCAGGCGAGTTGTCATCACAGGCATTGG
ACTAGTGACACCACTTGGCGTTGGGACTCAACTAGTTTGGGATCGGCTTCTCCGAGGAGAAAGT
GGAATTGTTTCTGTAGTTGGTGATGAGTACAAGAGTATTCCTTGCAGTGTAGCTGCTTTTGTAC
CAAGAGGTTCAGATAAAGGTCAGTTTAATGAACAAAACTTTGTGTCCAAATCAGATGCCAAGTC
CATGTCCTCTCCCACCATCATGGCGGTCGGAGCAGCAGAGTTGGCCCTGAAAGACTCCGGCTGG
TATCCAAAACTAGAAGCAGATCAGGTGGCTACTGGCGTTGCCATTGGCATGGGCATGGTTCCTC
TGGAAGTTGTTTCTGAAACTGCTTTAATGTTTCAAACCAAAGGTTATAGTAAAGTAAGCCCATT
CTTTGTCCCTAAGATTCTGATCAATATGGCTGCAGGCCAGGTCAGCATTCGCTACAAACTCAAA
GGCCCCAATCATTCAGTGTCTACAGCCTGTACCACGGGTGCACATGCTGTGGGAGACTCTTTTA
GACTTATAGCCCATGGTGACGCAGATGTGATGGTGGCTGGAGGCACAGACTCTTGTATTAGTCC
GTTATCTCTCGCTGGGTTTTCCAGAGCCCGGGCTCTAAGCACGAACCCAGATCCTAAGCTGGCC
TGCCGACCATTTCATCCAGAAAGAGATGGTTTTGTCATGGGTGAGGGAGCTGCTGTACTGGTGC
TAGAAGAACATGAACATGCTGTTCAGAGAGGAGCCCGGATCTACGCAGAAGTTTTGGGTTATGG
ACTCTCAGGTGATGCTGGTCACATAACTGCCCCCGATCCTGAAGGAGAAGGTGCTTTAAGATGC
ATGGCTGCTGCTGTAAAAGATGCAGGCGTATCACCTGATCAGATATCCTATGTCAACGCACATG
CCACCTCCACACCACTGGGTGACGCTGCTGAGAACAGAGCCATCAAGAGGCTCTTTAGGGACCA
TGCTCGTGCCCTCGCCATATCCTCCACAAAGGGAGCCACGGGGCATCTTCTGGGAGCTGCAGGG
GCAGTCGAGGCAGCTTTCACTGCACTGGCTTGTTACCATCACAAACTACCGCCAACTTTAAACC
TGGATTGTACAGAGGCAGAATTTGATCTCAATTATGTTCCACTGGAGGCACAGGAATGGAAAAC
CGAGGGTCGATGTATTGGACTCACCAATTCCTTCGGGTTTGGTGGTACTAATGCGACACTTTGT
ATTGCTGGCATGTAAGCTTTGGCTTTCAATAGTCATAAATGTATAAATAGTATGCACATAAATG
TCTTATCAGTGCCCAGGTGACTCTAGCCTACTTGGTATTTGTACAGTTCTTTGCTAGTGAACAG
GCTACCTAGTACTTGTCGGTATTTTATAGCATCTTGGTGTCTCCTGTGAGATTTCAGTGGCAAC
TGTGACAACTAGAAATGTCTCTGGAGGACAGGATAGCCTGCACACAGAACTACTGATTTATATT
TTTCTAACGCACTATTTCACCCATCCCTGTCCTTTTTAGATATTTATTTAGAGACTAGCTCCTC
TGAGCAAGGCTGTGTTGCTTCATGGTGTAACTCTAGGGGCACCACTGTCATACAGCATATAGGG
AGGAATGTAATACAAGTAGGAGTATGCATCATCAGGCAGCATCCTTTGAGGACAACTGTCAGTC
AATTATGGCCTAGTCACCCCTGACCTGTGTAGGTCTCCTCAGTGGATTTTCCCCCAAGCTTTCA
TTTCTCTGAAGGAGGAAGTGAAGCTGATTTGGCATTTTTCTTGTCTTTTCTCATTTGTCCTTCC
TTCCTTCCTTCCTTTCTCCTCCTCTTCTTCTCCTTCCTCCTCTTCTTCCTCCCCTTTCTCCTCT
TCCTCCCCTCCCCCTTTCTCCTCTTCCCCTTCCTCCTCTTCTTCTCCTTCCTCCTCTTCTTCCT
CCCCTTTCTCCTCTTCCTCCCCTTCCTCCTCTTCCCCTTTCTCCTCTTCCCCTTCCTCTTCCTC
CCCTTCCTCCTCCTCTTCCTCCCCTTCCTCCTCTTCCTCCCCTTCCTCCTCCTCTTCCTCCCCT
TCCTCCTCTTCCTCCCCTTCCTCCTCCTCTTCCTCCCCTTCCTCCTCTTCCTCCCCTTCCTCCT
CCCCTCCTCCCCTTCCTCCCCTTCCTCCTCCTCTTCCTCCTCCCCTCCTCCTCTTCCTCTTCCT
CCCCCTCTTCCTCCTCTTCCTCTTCTTTCTCCTCTTCCTCCTCCTCTTCCTCCTCTACTTCTTT
GAGACTGGGTTTCTCTTGGAACTCATTCTATAAACCCTGGCTGGCCTTGAACTCAACAAAGATC
TGTTTGCCTCTGCCTCCCAAGTGCTACTATTAAAGGTGTACACCAC

hide sequence

RefSeq Acc Id:

XM_039093089 ⟹ XP_038949017

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	9,210,443 - 9,215,852 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001093978	(Get FASTA)	NCBI Sequence Viewer
	XP_006251773	(Get FASTA)	NCBI Sequence Viewer
	XP_038949017	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH90025	(Get FASTA)	NCBI Sequence Viewer
	EDL94095	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001093978 ⟸ NM_001100508

- UniProtKB:

G3V6R7 (UniProtKB/TrEMBL), A6K049 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLSKCLQHFLKAHLYPASYCWLISKHKFSGSVPAAGSRRRVVITGIGLVTPLGVGTQLVWDRLL
RGESGIVSVVGDEYKSIPCSVAAFVPRGSDKGQFNEQNFVSKSDAKSMSSPTIMAVGAAELALK
DSGWYPKLEADQVATGVAIGMGMVPLEVVSETALMFQTKGYSKVSPFFVPKILINMAAGQVSIR
YKLKGPNHSVSTACTTGAHAVGDSFRLIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNPD
PKLACRPFHPERDGFVMGEGAAVLVLEEHEHAVQRGARIYAEVLGYGLSGDAGHITAPDPEGEG
ALRCMAAAVKDAGVSPDQISYVNAHATSTPLGDAAENRAIKRLFRDHARALAISSTKGATGHLL
GAAGAVEAAFTALACYHHKLPPTLNLDCTEAEFDLNYVPLEAQEWKTEGRCIGLTNSFGFGGTN
ATLCIAGM

hide sequence

RefSeq Acc Id:	XP_006251773 ⟸ XM_006251711
- Peptide Label:	isoform X1
- UniProtKB:	G3V6R7 (UniProtKB/TrEMBL), A6K049 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLSKCLQHFLKAHLYPASYCWLISKHKFSGSVPAAGSRRRVVITGIGLVTPLGVGTQLVWDRLL RGESGIVSVVGDEYKSIPCSVAAFVPRGSDKGQFNEQNFVSKSDAKSMSSPTIMAVGAAELALK DSGWYPKLEADQVATGVAIGMGMVPLEVVSETALMFQTKGYSKVSPFFVPKILINMAAGQVSIR YKLKGPNHSVSTACTTGAHAVGDSFRLIAHGDADVMVAGGTDSCISPLSLAGFSRARALSTNPD PKLACRPFHPERDGFVMGEGAAVLVLEEHEHAVQRGARIYAEVLGYGLSGDAGHITAPDPEGEG ALRCMAAAVKDAGVSPDQISYVNAHATSTPLGDAAENRAIKRLFRDHARALAISSTKGATGHLL GAAGAVEAAFTALACYHHKLPPTLNLDCTEAEFDLNYVPLEAQEWKTEGRCIGLTNSFGFGGTN ATLCIAGM hide sequence

RefSeq Acc Id:

ENSRNOP00000008035 ⟸ ENSRNOT00000008035

RefSeq Acc Id:

ENSRNOP00000074133 ⟸ ENSRNOT00000078249

RefSeq Acc Id:	XP_038949017 ⟸ XM_039093089
- Peptide Label:	isoform X1
- UniProtKB:	G3V6R7 (UniProtKB/TrEMBL), A6K049 (UniProtKB/TrEMBL)

Protein Domains

Ketosynthase family 3 (KS3)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-G3V6R7-F1-model_v2	AlphaFold	G3V6R7	1-456	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311092	AgrOrtholog
BioCyc Gene	G2FUF-14429	BioCyc
BioCyc Pathway	PWY66-429 [fatty acid biosynthesis initiation (mitochondria)]	BioCyc
	PWY66-430 [tetradecanoate biosynthesis (mitochondria)]	BioCyc
Ensembl Genes	ENSRNOG00000005993	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000008035	ENTREZGENE
	ENSRNOP00000008035.4	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000008035	ENTREZGENE
	ENSRNOT00000008035.6	UniProtKB/TrEMBL
Gene3D-CATH	3.40.47.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7364934	IMAGE-MGC_LOAD
InterPro	3-oxoacyl-ACP_synth-2	UniProtKB/TrEMBL
	Beta-ketoacyl_synthase	UniProtKB/TrEMBL
	Ketoacyl_synth_AS	UniProtKB/TrEMBL
	Ketoacyl_synth_C	UniProtKB/TrEMBL
	Ketoacyl_synth_N	UniProtKB/TrEMBL
	PKS_Beta-ketoAc_synthase_dom	UniProtKB/TrEMBL
	Thiolase-like	UniProtKB/TrEMBL
KEGG Report	rno:289934	UniProtKB/TrEMBL
MGC_CLONE	MGC:109568	IMAGE-MGC_LOAD
NCBI Gene	289934	ENTREZGENE
PANTHER	3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE, MITOCHONDRIAL	UniProtKB/TrEMBL
	PTHR11712	UniProtKB/TrEMBL
Pfam	ketoacyl-synt	UniProtKB/TrEMBL
	Ketoacyl-synt_C	UniProtKB/TrEMBL
PhenoGen	Oxsm	PhenoGen
PIRSF	KAS_II	UniProtKB/TrEMBL
PROSITE	B_KETOACYL_SYNTHASE	UniProtKB/TrEMBL
	KS3_2	UniProtKB/TrEMBL
SMART	PKS_KS	UniProtKB/TrEMBL
Superfamily-SCOP	Thiolase-like	UniProtKB/TrEMBL
UniProt	A6K049	ENTREZGENE, UniProtKB/TrEMBL
	G3V6R7	ENTREZGENE, UniProtKB/TrEMBL
	Q5EB57_RAT	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-02-27	Oxsm	3-oxoacyl-ACP synthase, mitochondrial	RGD1311092	similar to hypothetical protein FLJ20604	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-01-09	RGD1311092	similar to hypothetical protein FLJ20604	LOC498451	similar to hypothetical protein FLJ20604	Data Merged	1643240	APPROVED
2006-11-20	LOC498451	similar to hypothetical protein FLJ20604			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-12-06	RGD1311092	similar to hypothetical protein FLJ20604	RGD1311092_predicted	similar to hypothetical protein FLJ20604 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1311092_predicted	similar to hypothetical protein FLJ20604 (predicted)	LOC289934_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC289934_predicted	similar to hypothetical protein FLJ20604 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)

Send us a Message

Imported Disease Annotations - ClinVar

Imported Annotations - KEGG (archival)