Ltb4r (leukotriene B4 receptor) - Rat Genome Database

Name: Ltb4r
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Ltb4r (leukotriene B4 receptor) Rattus norvegicus

Analyze

Symbol:

Ltb4r

Name:

leukotriene B4 receptor

RGD ID:

620410

Description:

Enables leukotriene receptor activity. Involved in inflammatory response. Located in membrane raft. Used to study carotid artery disease. Orthologous to human LTB4R (leukotriene B4 receptor); PARTICIPATES IN G protein mediated signaling pathway; INTERACTS WITH 1,2-dimethylhydrazine; 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid; ammonium chloride.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

BLT-1; BLT1; leukotriene B4 receptor 1; LTB4-R 1; LTB4-R1; Ltb4r1

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	LTB4R (leukotriene B4 receptor)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ltb4r1 (leukotriene B4 receptor 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ltb4r (leukotriene B4 receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	LTB4R (leukotriene B4 receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	LTB4R (leukotriene B4 receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ltb4r (leukotriene B4 receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LTB4R (leukotriene B4 receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	LTB4R (leukotriene B4 receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ltb4r (leukotriene B4 receptor)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	LTB4R (leukotriene B4 receptor)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ltb4r1 (leukotriene B4 receptor 1)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ltb4r (leukotriene B4 receptor)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	29,263,126 - 29,265,716 (+)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	15	31,110,164 - 31,111,219 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	32,257,374 - 32,258,429 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	30,499,723 - 30,500,778 (+)	NCBI	Rnor_WKY
Rnor_6.0	15	34,449,299 - 34,453,352 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,452,116 - 34,453,171 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	38,337,878 - 38,341,864 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	33,928,726 - 33,929,781 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	33,944,425 - 33,945,481 (+)	NCBI
Celera	15	28,839,411 - 28,840,466 (+)	NCBI		Celera
Cytogenetic Map	15	p13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Anaphylaxis (ISO)

arteriosclerosis (ISO)

Brain-Lung-Thyroid Syndrome (ISO)

carotid artery disease (IDA)

Chemical and Drug Induced Liver Injury (ISO)

Helicobacter Infections (ISO)

Inflammation (ISO)

liver disease (ISO)

nephrosclerosis (ISO)

otitis media (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-acetyl-1-alkyl-sn-glycero-3-phosphocholine (ISO)

3,3',5-triiodo-L-thyronine (ISO)

3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid (EXP)

4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one (ISO)

5-azacytidine (ISO)

acrylamide (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

arachidonic acid (ISO)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bis(2-chloroethyl) sulfide (ISO)

bisphenol A (EXP)

buta-1,3-diene (ISO)

calciol (ISO)

calcitriol (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clopidogrel (ISO)

copper atom (ISO)

copper(0) (ISO)

dextran sulfate (ISO)

dibenz[a,h]anthracene (ISO)

dichloroacetic acid (ISO)

dioxygen (EXP,ISO)

disulfiram (ISO)

flavonoids (EXP)

formaldehyde (EXP,ISO)

furan (ISO)

gentamycin (EXP)

hydroxyurea (ISO)

leukotriene B4 (ISO)

lipopolysaccharide (ISO)

methotrexate (ISO)

Methylazoxymethanol acetate (EXP)

nickel atom (ISO)

nitrobenzenes (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

pirinixic acid (ISO)

potassium dichromate (ISO)

quercetin (ISO)

tamibarotene (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

titanium dioxide (ISO)

trichloroethene (EXP)

triptonide (ISO)

vinclozolin (EXP)

zinc dichloride (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

inflammatory response (IBA,IEP)

leukotriene signaling pathway (ISO)

neuropeptide signaling pathway (IBA)

signal transduction (ISO)

Cellular Component

membrane raft (IDA)

plasma membrane (IBA)

Molecular Function

G protein-coupled peptide receptor activity (IBA)

leukotriene B4 receptor activity (IBA,ISO)

leukotriene receptor activity (IDA)

protein binding (IPI)

Molecular Pathway Annotations Click to see Annotation Detail View

G protein mediated signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Leukotriene B4 signaling through NF-kappaB-dependent BLT1 receptors on vascular smooth muscle cells in atherosclerosis and intimal hyperplasia.	Back M, etal., Proc Natl Acad Sci U S A. 2005 Nov 29;102(48):17501-6. Epub 2005 Nov 17.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Inhibition of atherogenesis in BLT1-deficient mice reveals a role for LTB4 and BLT1 in smooth muscle cell recruitment.	Heller EA, etal., Circulation. 2005 Jul 26;112(4):578-86.
4.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
5.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
6.	GOA pipeline	RGD automated data pipeline
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
8.	FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.	Serezani CH, etal., Blood. 2009 Oct 8;114(15):3316-24. doi: 10.1182/blood-2009-01-199919. Epub 2009 Aug 5.
9.	Cloning and characterization of rat leukotriene B(4) receptor.	Toda A, etal., Biochem Biophys Res Commun 1999 Sep 7;262(3):806-12.
10.	The long-term effect of Helicobacter pylori eradication on COX-1/2, 5-LOX and leukotriene receptors in patients with a risk gastritis phenotype--a link to gastric carcinogenesis.	Venerito M, etal., Cancer Lett. 2008 Nov 8;270(2):218-28. doi: 10.1016/j.canlet.2008.05.015. Epub 2008 Jun 20.

Additional References at PubMed

PMID:15561704	PMID:15866883	PMID:17481560	PMID:20403205	PMID:21189570	PMID:27725151

Genomics

Comparative Map Data

Ltb4r
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	29,263,126 - 29,265,716 (+)	NCBI	mRatBN7.2	mRatBN7.2
UTH_Rnor_SHR_Utx	15	31,110,164 - 31,111,219 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	32,257,374 - 32,258,429 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	30,499,723 - 30,500,778 (+)	NCBI	Rnor_WKY
Rnor_6.0	15	34,449,299 - 34,453,352 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	34,452,116 - 34,453,171 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	38,337,878 - 38,341,864 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	33,928,726 - 33,929,781 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	33,944,425 - 33,945,481 (+)	NCBI
Celera	15	28,839,411 - 28,840,466 (+)	NCBI		Celera
Cytogenetic Map	15	p13	NCBI

LTB4R
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	24,311,502 - 24,318,036 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	14	24,311,450 - 24,318,036 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	24,780,708 - 24,787,242 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	23,852,357 - 23,855,992 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	14	23,852,356 - 23,855,990	NCBI
Celera	14	4,645,334 - 4,651,863 (+)	NCBI		Celera
Cytogenetic Map	14	q12	NCBI
HuRef	14	4,895,872 - 4,902,130 (+)	NCBI		HuRef
CHM1_1	14	24,779,305 - 24,785,834 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	14	18,509,845 - 18,516,371 (+)	NCBI		T2T-CHM13v2.0

Ltb4r1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	56,003,419 - 56,005,949 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	56,003,419 - 56,005,951 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	55,765,962 - 55,768,492 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	55,765,962 - 55,768,494 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	56,384,799 - 56,387,329 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	54,720,087 - 54,722,560 (+)	NCBI		MGSCv36	mm8
Celera	14	53,570,996 - 53,573,526 (+)	NCBI		Celera
Cytogenetic Map	14	C3	NCBI
cM Map	14	28.19	NCBI

Ltb4r
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955409	35,984,933 - 35,985,976 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955409	35,984,757 - 35,991,492 (-)	NCBI	ChiLan1.0	ChiLan1.0

LTB4R
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	14	23,211,859 - 23,217,861 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	23,215,469 - 23,216,527 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	14	5,088,907 - 5,094,571 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

LTB4R
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	4,282,924 - 4,286,869 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	4,285,323 - 4,286,534 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	4,206,403 - 4,208,655 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	4,395,506 - 4,397,677 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	8	4,395,197 - 4,397,891 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	8	4,085,854 - 4,088,025 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	4,147,678 - 4,149,852 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	4,410,263 - 4,412,434 (+)	NCBI		UU_Cfam_GSD_1.0

Ltb4r
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	36,153,951 - 36,157,722 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936722	232,320 - 233,802 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LTB4R
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	74,974,308 - 74,975,357 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	74,972,723 - 74,978,266 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	80,243,663 - 80,248,968 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

LTB4R
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	1,294,453 - 1,301,113 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	1,298,729 - 1,299,790 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666036	12,978,984 - 12,985,650 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ltb4r
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624820	8,187,496 - 8,189,562 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624820	8,187,496 - 8,196,381 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ltb4r
3 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	119
Count of miRNA genes:	101
Interacting mature miRNAs:	102
Transcripts:	ENSRNOT00000027647
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354657	Despr13	Despair related QTL 13		0.0022	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	15	1	29912054	Rat
8552920	Pigfal8	Plasma insulin-like growth factor 1 level QTL 8	3		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	15	1	34723002	Rat
8694361	Abfw6	Abdominal fat weight QTL 6	10.2	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	15	1	34723002	Rat
9589149	Insul29	Insulin level QTL 29	9.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	15	1	34723002	Rat
731170	Pur3	Proteinuria QTL 3	2.3	0.0005	urine protein amount (VT:0005160)	urine protein excretion rate (CMO:0000759)	15	1	41686771	Rat
1641887	Alcrsp14	Alcohol response QTL 14			response to alcohol trait (VT:0010489)	brain neurotensin receptor 1 density (CMO:0002068)	15	1	42356671	Rat
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
10401805	Kidm51	Kidney mass QTL 51			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	15	306329	45306329	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
631550	Bw7	Body weight QTL 7	3.6		body mass (VT:0001259)	body weight (CMO:0000012)	15	19856566	34924750	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	19856566	46187442	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat

Markers in Region

D15Wox12

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	29,263,537 - 29,263,754 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	34,451,175 - 34,451,391	NCBI	Rnor6.0
Rnor_5.0	15	38,339,687 - 38,339,903	UniSTS	Rnor5.0
RGSC_v3.4	15	33,927,785 - 33,928,001	UniSTS	RGSC3.4
Celera	15	28,838,470 - 28,838,686	UniSTS
Cytogenetic Map	15	p13	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium
Low			13	12	7	12			6	4	11	8
Below cutoff	3	28	30	20	9	20	7	10	53	30	24	3	7

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_021656	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599791	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB025230	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC116083	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474049	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000268	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000027647 ⟹ ENSRNOP00000027647

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	15	34,452,116 - 34,453,171 (+)	Ensembl

RefSeq Acc Id:

NM_021656 ⟹ NP_067688

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	29,264,479 - 29,265,534 (+)	NCBI
Rnor_6.0	15	34,452,116 - 34,453,171 (+)	NCBI
Rnor_5.0	15	38,337,878 - 38,341,864 (+)	NCBI
RGSC_v3.4	15	33,928,726 - 33,929,781 (+)	RGD
Celera	15	28,839,411 - 28,840,466 (+)	RGD

Sequence:

show sequence

ATGGCTGCAAACACTACATCTACTGCAGCAACTTCTTCTCCTGGTGGCATGTCCCTGTCTCTGT
TGCCCATTGTCCTGCTGTCTGTGGCCCTGGTTGTGGGGCTTCCCGGCAATAGCTTTGTCGTGTG
GAGCATCCTGAAAAGGATGCAGAAACGCTCTGTCACCGCCCTGCTGGTGCTGAACTTGGCCCTG
GCCGACCTGGCCGTGTTGCTCACTGCTCCCTTTTTCCTACACTTTCTGGCTCGGGGCACCTGGA
GTTTTGAAGTGACCGGTTGCCGCCTGTGTCACTATGTCTGTGGAGTAAGCATGTATGCCAGCGT
CCTGCTTATCACTATCATGAGCCTGGACCGCTCACTGGCAGTTGCCCGCCCCTTTGTGTCCCAA
AAGGTTCGTACTAAAGCCTTTGCCCGATGGGTGCTGGCAGGTATCTGGGTGGTGTCTTTTCTGC
TGGCCATACCGGTCCTTGTGTACCGCACAGTAACACCCAAGAACAAGACGTTGATCTGCGACTC
GAGGTATCCCAGCGACGGGCATAAAGTCTTTCATCTGCTCTTTGAAGCCATCACGGGCTTCCTG
CTGCCCTTCCTGGCGGTGGTGGCCAGCTACTCTGACATCGGGCGCAGGCTGCAGGCTCGGCGCT
TCCGCCGCAGCCGCCGCACCGGTCGCCTGGTGGTGCTCATTATCCTGGCCTTCGCCGCCTTCTG
GCTGCCTTATCACCTGGTGAACCTGGTGGAAGCTGGCCGCACGCTGGCCGGCTGGGACAAGAAC
AGCCCTGCTGGGCAGCGTCTGAAGCTGGCCCGCTACGTGCTGATCGCGCTGGCCTTCCTGAGCA
GCAGCGTGAACCCGGTGCTGTACGCGTGCGCAGGCGGCGGCCTGCTTCGTTCGGCGGGCGTGGG
CTTCGTAGTCAAGCTGCTCGAGGGCACTGGCTCCGAGGTGTCCAGCACCCGTCGCGGAGGCACT
TTGGTCCAGACCCCGAAGGCCACACCCACCTGTCCTGAACCGGGCCCCACCGACAGCTTCATGA
CTTCCTCCACCCCTCCTGAATCTTCGAAGTGA

hide sequence

RefSeq Acc Id:

XM_006252011 ⟹ XP_006252073

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	29,263,126 - 29,265,716 (+)	NCBI
Rnor_6.0	15	34,449,299 - 34,453,352 (+)	NCBI
Rnor_5.0	15	38,337,878 - 38,341,864 (+)	NCBI

Sequence:

show sequence

ACTGCTTCCCAAGGAAGAAGGAGTGAGGAAAACCCAGGGAGAGAGTGCAGAGAACCCACCACTG
GCTTGGAAGGGCTGGAGAGGACCCCAGCGCTCTGAGCCCAAAGCTTCATTCTGAAACACAGAAT
CCTTCCTGCCCTGGTGCTCTGGAGCAGGGTCTCCTGAACTTCCCCTGTTGTACACTCTTCACCT
TACACACCCCGTGTGGTCAGAGAGATCCTTCCTCAACTCTGCCCTCTGTTCTTGCTGTGGTTTA
GCCCCCCCTTTCATCATATCCTCTGCCTGACAGTTACTGGGTCAGTGCTGATCTGGCTTTTCTC
ACTGTTCAGCAAGTGAGATCACTGGAGAAAGAGCATAAGGGACGCCAGGGACCACCCTTTTGCC
ACCTTTCACCTTTTCTGAGAAGTGACAAGTCAAAAGACAAACAGAAAGGCTCCTGGCAGACTGA
AGGGATGTGTTCTTGGTACCACACTTCAAGGAGAGCCAGCATCCTTTCTTTCGCTGAGGGGAGT
AGAAGGGTAACGCTGTGGTGGCTGTGTAATTTTCCGAATTCTTAGATGCTCTCATGGCAGGGCT
GGAGGGCGGCGCTGCTGGCCCTGGGCCACCCTGTCTCTTCTTGTTTGATGTTCTCAGCATCCCC
TAGCTTAGCCCACACTCTGTCAGAGTTGAAACTAGACGGCGCAAGGCTGTGTGGATGTAGGAAA
GGGATGTGGATTCTTGCCTAGATCCCAGTAAGAAGGTCAACCAGGGCTACTAAATGGTCAAGTG
GCTAAGGTAAGGGGAAGACCTCGGTGCTTTGTGTCACAAAGGAGATCACTTAGACTTTGGTGTC
TCTCTCAAAGAATGGAGAATTGGCTAACCTGGAGAGAGCAGTGCTGGGCATGGCTGTTTCCTAT
AACCACACCACAGTCATGGTCTGACCTGAAGCCAAGAACAGGCTGTGGTTCCCTCTGTTCATTT
TTTTTTTTTACATTCTCATTGATATTCTTACTCTTTATGCCCCCTCCCCTCCAGTGTCTGTGGA
TCTGCCTCTCAATCTCATATAGCCTAGGGTGGCTTGACCCCAATATGCTGTTTTTAGATCATGA
TGATGTTACCCTAACTCGTAACAATACACAGAACATAGGTGGTCAACCTAATCTAAAAACCCAT
TAATCTAAAAACCACGGCTTGCGCACGTTGTTAATGTGAAGTACAAAGATAATATATTTTTTTA
ATTAGCAGTCTCAATCTTCTCCTTCTGCCTTGCTTCCTTCTCCTATGATACAATCCGTAATTTT
GTTCACTTCTCCAGTCCAGACTTGCACTTTTAGACCACACCCCAAGCCAAGTCACTCCTGGCAC
CCCTCTTTCCTATCTCAGCTGCCCTTTCCTGGCTACTACTCACTTAGCCCCACCCAAAGAGTCT
TCCTCCCTTCTGGACTGCTCTGGAACACAGACTGTCCCTCCCCAACAGTGAAGGGAGGTGTGGG
GGTTTTCAGCCTCACCCTCAGGAAGATGCTCCCCGGCCCCTGCCTCCTTTGCTCTGCTCTGTGG
TACTTCCTCTCTGGCTGTCTTAGCTGACAGACCTAGAAGTGGGACCAAGACCCTAGCACTAAGA
CAGATTCAAGGACTGTATATCCAACTACTAGACGTGTGTTACCTTCTGATCAGCATCTGAAAAA
CCCTGACCTTTTGATGGCTGCAAACACTACATCTACTGCAGCAACTTCTTCTCCTGGTGGCATG
TCCCTGTCTCTGTTGCCCATTGTCCTGCTGTCTGTGGCCCTGGTTGTGGGGCTTCCCGGCAATA
GCTTTGTCGTGTGGAGCATCCTGAAAAGGATGCAGAAACGCTCTGTCACCGCCCTGCTGGTGCT
GAACTTGGCCCTGGCCGACCTGGCCGTGTTGCTCACTGCTCCCTTTTTCCTACACTTTCTGGCT
CGGGGCACCTGGAGTTTTGAAGTGACCGGTTGCCGCCTGTGTCACTATGTCTGTGGAGTAAGCA
TGTATGCCAGCGTCCTGCTTATCACTATCATGAGCCTGGACCGCTCACTGGCAGTTGCCCGCCC
CTTTGTGTCCCAAAAGGTTCGTACTAAAGCCTTTGCCCGATGGGTGCTGGCAGGTATCTGGGTG
GTGTCTTTTCTGCTGGCCATACCGGTCCTTGTGTACCGCACAGTAACACCCAAGAACAAGACGT
TGATCTGCGACTCGAGGTATCCCAGCGACGGGCATAAAGTCTTTCATCTGCTCTTTGAAGCCAT
CACGGGCTTCCTGCTGCCCTTCCTGGCGGTGGTGGCCAGCTACTCTGACATCGGGCGCAGGCTG
CAGGCTCGGCGCTTCCGCCGCAGCCGCCGCACCGGTCGCCTGGTGGTGCTCATTATCCTGGCCT
TCGCCGCCTTCTGGCTGCCTTATCACCTGGTGAACCTGGTGGAAGCTGGCCGCACGCTGGCCGG
CTGGGACAAGAACAGCCCTGCTGGGCAGCGTCTGAAGCTGGCCCGCTACGTGCTGATCGCGCTG
GCCTTCCTGAGCAGCAGCGTGAACCCGGTGCTGTACGCGTGCGCAGGCGGCGGCCTGCTTCGTT
CGGCGGGCGTGGGCTTCGTAGTCAAGCTGCTCGAGGGCACTGGCTCCGAGGTGTCCAGCACCCG
TCGCGGAGGCACTTTGGTCCAGACCCCGAAGGCCACACCCACCTGTCCTGAACCGGGCCCCACC
GACAGCTTCATGACTTCCTCCACCCCTCCTGAATCTTCGAAGTGAACTGTAGTAGGTTGGGTTA
TGACACAACTCATAACTTGGAGGAGAACCTGGAGGAGAACATGTTGGGGACTGGGCTAAAGTGG
AAAAGAGGGAGGGGTGGGGCAAGTCAGGGCAGAGAGATAGCATGCTCTGTCCTGGCTTCTGCAG
GCAGCCTTACGATTAAAACTAAAGTCTAAAGCCA

hide sequence

RefSeq Acc Id:

XM_006252012 ⟹ XP_006252074

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	29,263,540 - 29,265,716 (+)	NCBI
Rnor_6.0	15	34,451,456 - 34,453,352 (+)	NCBI
Rnor_5.0	15	38,337,878 - 38,341,864 (+)	NCBI

Sequence:

show sequence

CCGAACCCAGGGCCTTGTGCTTCCTAGGACCTTTTGATGGCTGCAAACACTACATCTACTGCAG
CAACTTCTTCTCCTGGTGGCATGTCCCTGTCTCTGTTGCCCATTGTCCTGCTGTCTGTGGCCCT
GGTTGTGGGGCTTCCCGGCAATAGCTTTGTCGTGTGGAGCATCCTGAAAAGGATGCAGAAACGC
TCTGTCACCGCCCTGCTGGTGCTGAACTTGGCCCTGGCCGACCTGGCCGTGTTGCTCACTGCTC
CCTTTTTCCTACACTTTCTGGCTCGGGGCACCTGGAGTTTTGAAGTGACCGGTTGCCGCCTGTG
TCACTATGTCTGTGGAGTAAGCATGTATGCCAGCGTCCTGCTTATCACTATCATGAGCCTGGAC
CGCTCACTGGCAGTTGCCCGCCCCTTTGTGTCCCAAAAGGTTCGTACTAAAGCCTTTGCCCGAT
GGGTGCTGGCAGGTATCTGGGTGGTGTCTTTTCTGCTGGCCATACCGGTCCTTGTGTACCGCAC
AGTAACACCCAAGAACAAGACGTTGATCTGCGACTCGAGGTATCCCAGCGACGGGCATAAAGTC
TTTCATCTGCTCTTTGAAGCCATCACGGGCTTCCTGCTGCCCTTCCTGGCGGTGGTGGCCAGCT
ACTCTGACATCGGGCGCAGGCTGCAGGCTCGGCGCTTCCGCCGCAGCCGCCGCACCGGTCGCCT
GGTGGTGCTCATTATCCTGGCCTTCGCCGCCTTCTGGCTGCCTTATCACCTGGTGAACCTGGTG
GAAGCTGGCCGCACGCTGGCCGGCTGGGACAAGAACAGCCCTGCTGGGCAGCGTCTGAAGCTGG
CCCGCTACGTGCTGATCGCGCTGGCCTTCCTGAGCAGCAGCGTGAACCCGGTGCTGTACGCGTG
CGCAGGCGGCGGCCTGCTTCGTTCGGCGGGCGTGGGCTTCGTAGTCAAGCTGCTCGAGGGCACT
GGCTCCGAGGTGTCCAGCACCCGTCGCGGAGGCACTTTGGTCCAGACCCCGAAGGCCACACCCA
CCTGTCCTGAACCGGGCCCCACCGACAGCTTCATGACTTCCTCCACCCCTCCTGAATCTTCGAA
GTGAACTGTAGTAGGTTGGGTTATGACACAACTCATAACTTGGAGGAGAACCTGGAGGAGAACA
TGTTGGGGACTGGGCTAAAGTGGAAAAGAGGGAGGGGTGGGGCAAGTCAGGGCAGAGAGATAGC
ATGCTCTGTCCTGGCTTCTGCAGGCAGCCTTACGATTAAAACTAAAGTCTAAAGCCA

hide sequence

Protein Sequences


Protein RefSeqs	NP_067688	(Get FASTA)	NCBI Sequence Viewer
	XP_006252073	(Get FASTA)	NCBI Sequence Viewer
	XP_006252074	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAA84578	(Get FASTA)	NCBI Sequence Viewer
	EDM14281	(Get FASTA)	NCBI Sequence Viewer
	Q9R0Q2	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_067688 ⟸ NM_021656

- UniProtKB:

Q9R0Q2 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MAANTTSTAATSSPGGMSLSLLPIVLLSVALVVGLPGNSFVVWSILKRMQKRSVTALLVLNLAL
ADLAVLLTAPFFLHFLARGTWSFEVTGCRLCHYVCGVSMYASVLLITIMSLDRSLAVARPFVSQ
KVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVTPKNKTLICDSRYPSDGHKVFHLLFEAITGFL
LPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTLAGWDKN
SPAGQRLKLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGT
LVQTPKATPTCPEPGPTDSFMTSSTPPESSK

hide sequence

RefSeq Acc Id:	XP_006252073 ⟸ XM_006252011
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0Q2 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAANTTSTAATSSPGGMSLSLLPIVLLSVALVVGLPGNSFVVWSILKRMQKRSVTALLVLNLAL ADLAVLLTAPFFLHFLARGTWSFEVTGCRLCHYVCGVSMYASVLLITIMSLDRSLAVARPFVSQ KVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVTPKNKTLICDSRYPSDGHKVFHLLFEAITGFL LPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTLAGWDKN SPAGQRLKLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGT LVQTPKATPTCPEPGPTDSFMTSSTPPESSK hide sequence

RefSeq Acc Id:	XP_006252074 ⟸ XM_006252012
- Peptide Label:	isoform X1
- UniProtKB:	Q9R0Q2 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MAANTTSTAATSSPGGMSLSLLPIVLLSVALVVGLPGNSFVVWSILKRMQKRSVTALLVLNLAL ADLAVLLTAPFFLHFLARGTWSFEVTGCRLCHYVCGVSMYASVLLITIMSLDRSLAVARPFVSQ KVRTKAFARWVLAGIWVVSFLLAIPVLVYRTVTPKNKTLICDSRYPSDGHKVFHLLFEAITGFL LPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILAFAAFWLPYHLVNLVEAGRTLAGWDKN SPAGQRLKLARYVLIALAFLSSSVNPVLYACAGGGLLRSAGVGFVVKLLEGTGSEVSSTRRGGT LVQTPKATPTCPEPGPTDSFMTSSTPPESSK hide sequence

RefSeq Acc Id:

ENSRNOP00000027647 ⟸ ENSRNOT00000027647

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9R0Q2-F1-model_v2	AlphaFold	Q9R0Q2	1-351	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620410	AgrOrtholog
BioCyc Gene	G2FUF-13687	BioCyc
Ensembl Genes	ENSRNOG00000020399	Ensembl
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot
	Leukotriene_B4_rcpt	UniProtKB/Swiss-Prot
	Leukotriene_B4_typ-1_rcpt	UniProtKB/Swiss-Prot
KEGG Report	rno:59264	UniProtKB/Swiss-Prot
NCBI Gene	59264	ENTREZGENE
PANTHER	PTHR24230:SF51	UniProtKB/Swiss-Prot
Pfam	7tm_1	UniProtKB/Swiss-Prot
PhenoGen	Ltb4r	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot
	LTB1RECEPTOR	UniProtKB/Swiss-Prot
	LTBRECEPTOR	UniProtKB/Swiss-Prot
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot
UniProt	LT4R1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-09-18	Ltb4r	leukotriene B4 receptor	Ltb4r1	leukotriene B4 receptor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-25	Ltb4r1	leukotriene B4 receptor 1	Ltb4r	leukotriene B4 receptor	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-20	Ltb4r	leukotriene B4 receptor			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Ltb4r	leukotriene B4 receptor			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed only in polymorphonuclear leukocytes	633182
gene_homology	80.2, 93.2, and 71.6% amino acid identity to human, mouse, and guinea pig, respectively	633182
gene_protein	351 amino acids	633182

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

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RGD Manual Annotations