Gene: Pdhb (pyruvate dehydrogenase E1 beta subunit) Rattus norvegicus
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Symbol: Pdhb
Name: pyruvate dehydrogenase E1 beta subunit
Description: ENCODES a protein that exhibits pyruvate dehydrogenase (acetyl-transferring) activity; pyruvate dehydrogenase (NAD+) activity (ortholog); pyruvate dehydrogenase activity (ortholog); INVOLVED IN acetyl-CoA biosynthetic process from pyruvate; tricarboxylic acid cycle (ortholog); PARTICIPATES IN citric acid cycle pathway; fumaric aciduria disease pathway; Leigh syndrome pathway; ASSOCIATED WITH Carcinoma, Renal Cell (ortholog); Pyruvate Dehydrogenase Complex Deficiency Disease (ortholog); Pyruvate Dehydrogenase E1-Beta Deficiency (ortholog); FOUND IN mitochondrion; pyruvate dehydrogenase complex; nucleoplasm (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; aflatoxin B1
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC94149; PDHE1-B; pyruvate dehydrogenase (lipoamide) beta; pyruvate dehydrogenase E1 component subunit beta, mitochondrial
Orthologs:
Homo sapiens (human) : PDHB (pyruvate dehydrogenase E1 beta subunit)  HGNC  AGR
Mus musculus (house mouse) : Pdhb (pyruvate dehydrogenase (lipoamide) beta)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : Pdhb (pyruvate dehydrogenase E1 beta subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : PDHB (pyruvate dehydrogenase E1 beta subunit)
Canis lupus familiaris (dog) : PDHB (pyruvate dehydrogenase E1 beta subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pdhb (pyruvate dehydrogenase E1 beta subunit)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01518,540,826 - 18,546,855 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01522,507,861 - 22,513,890 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41518,737,449 - 18,743,391 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11518,737,448 - 18,743,390 (+)NCBI
Celera1516,710,789 - 16,716,731 (+)NCBICelera
Cytogenetic Map15p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pdhb
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1359146
Created: 2005-07-29
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE