Dlg5 (discs large MAGUK scaffold protein 5) - Rat Genome Database

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Gene: Dlg5 (discs large MAGUK scaffold protein 5) Rattus norvegicus
Analyze
Symbol: Dlg5
Name: discs large MAGUK scaffold protein 5
RGD ID: 1308753
Description: Predicted to enable beta-catenin binding activity and cytoskeletal protein binding activity. Predicted to be involved in several processes, including positive regulation of dendritic spine development; positive regulation of smoothened signaling pathway; and regulation of hippo signaling. Predicted to act upstream of or within several processes, including apical protein localization; morphogenesis of an epithelium; and protein localization to adherens junction. Predicted to be located in adherens junction; ciliary basal body; and postsynaptic density. Orthologous to human DLG5 (discs large MAGUK scaffold protein 5); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; aconitine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: discs large homolog 5; discs, large homolog 5; discs, large homolog 5 (Drosophila); disks large homolog 5; LOC305645
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21575,786 - 209,735 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1575,786 - 187,837 (+)Ensembl
Rnor_6.015120,213 - 230,312 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15120,372 - 228,977 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015115,133 - 225,208 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415118,948 - 207,783 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11574,450 - 322,113 (+)NCBI
Celera154,360,539 - 4,471,389 (-)NCBICelera
Cytogenetic Map15p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:8889548   PMID:12657639   PMID:17765678   PMID:23466739   PMID:25232112   PMID:25644602   PMID:28087714   PMID:28169360  


Genomics

Comparative Map Data
Dlg5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21575,786 - 209,735 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl1575,786 - 187,837 (+)Ensembl
Rnor_6.015120,213 - 230,312 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl15120,372 - 228,977 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.015115,133 - 225,208 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.415118,948 - 207,783 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11574,450 - 322,113 (+)NCBI
Celera154,360,539 - 4,471,389 (-)NCBICelera
Cytogenetic Map15p16NCBI
DLG5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381077,790,791 - 77,940,736 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1077,790,791 - 77,926,755 (-)EnsemblGRCh38hg38GRCh38
GRCh371079,550,549 - 79,686,513 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361079,220,555 - 79,356,354 (-)NCBINCBI36hg18NCBI36
Build 341079,220,556 - 79,298,959NCBI
Celera1072,837,188 - 72,972,945 (-)NCBI
Cytogenetic Map10q22.3NCBI
HuRef1073,545,075 - 73,623,451 (-)NCBIHuRef
CHM1_11079,833,321 - 79,969,137 (-)NCBICHM1_1
Dlg5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391424,184,021 - 24,295,988 (-)NCBIGRCm39mm39
GRCm39 Ensembl1424,184,021 - 24,295,988 (-)Ensembl
GRCm381424,133,953 - 24,245,920 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1424,133,953 - 24,245,920 (-)EnsemblGRCm38mm10GRCm38
MGSCv371424,953,175 - 25,065,142 (-)NCBIGRCm37mm9NCBIm37
MGSCv361422,966,418 - 23,078,385 (-)NCBImm8
Celera1420,508,965 - 20,620,834 (-)NCBICelera
Cytogenetic Map14A3NCBI
Dlg5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543714,510,488 - 14,628,768 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543714,510,488 - 14,628,768 (+)NCBIChiLan1.0ChiLan1.0
DLG5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11076,974,106 - 77,110,109 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1076,972,573 - 77,110,115 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01074,311,249 - 74,447,312 (-)NCBIMhudiblu_PPA_v0panPan3
DLG5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1427,687,223 - 27,780,007 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl427,687,287 - 27,806,722 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha427,812,670 - 27,931,793 (-)NCBI
ROS_Cfam_1.0427,989,064 - 28,108,333 (-)NCBI
ROS_Cfam_1.0 Ensembl427,989,135 - 28,108,809 (-)Ensembl
UMICH_Zoey_3.1427,863,475 - 27,982,805 (-)NCBI
UNSW_CanFamBas_1.0428,062,456 - 28,181,770 (-)NCBI
UU_Cfam_GSD_1.0428,414,697 - 28,534,135 (-)NCBI
Dlg5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721353,156,825 - 53,260,424 (+)NCBI
SpeTri2.0NW_0049365211,649,557 - 1,753,149 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DLG5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1480,249,693 - 80,377,505 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11480,249,693 - 80,377,496 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21486,782,895 - 86,907,451 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DLG5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1953,513,871 - 53,648,510 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl953,513,979 - 53,648,839 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604813,933,918 - 14,070,588 (+)NCBIVero_WHO_p1.0
Dlg5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475411,033,649 - 11,155,271 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
D15Rat55  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.215168,549 - 168,678 (+)MAPPERmRatBN7.2
Rnor_6.015211,024 - 211,152NCBIRnor6.0
Rnor_5.015205,920 - 206,048UniSTSRnor5.0
RGSC_v3.415188,498 - 188,626UniSTSRGSC3.4
RGSC_v3.415188,497 - 188,626RGDRGSC3.4
RGSC_v3.115188,497 - 188,626RGD
Celera154,379,628 - 4,379,756UniSTS
RH 3.4 Map1522.9RGD
RH 3.4 Map1522.9UniSTS
RH 2.0 Map150.0RGD
SHRSP x BN Map153.9298RGD
FHH x ACI Map150.0RGD
Cytogenetic Map15p16UniSTS
AA986715  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21587,669 - 87,797 (+)MAPPERmRatBN7.2
Rnor_6.015129,869 - 129,996NCBIRnor6.0
Rnor_5.015125,207 - 125,334UniSTSRnor5.0
RGSC_v3.41584,666 - 84,793UniSTSRGSC3.4
Celera154,459,619 - 4,459,746UniSTS
Cytogenetic Map15p16UniSTS
RH142459  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.215163,475 - 163,613 (+)MAPPERmRatBN7.2
Rnor_6.015205,950 - 206,087NCBIRnor6.0
Rnor_5.015200,846 - 200,983UniSTSRnor5.0
RGSC_v3.415183,424 - 183,561UniSTSRGSC3.4
Celera154,384,693 - 4,384,830UniSTS
RH 3.4 Map1518.7UniSTS
Cytogenetic Map15p16UniSTS
RH127943  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.215106,667 - 106,887 (+)MAPPERmRatBN7.2
mRatBN7.21033,173,170 - 33,174,731 (+)MAPPERmRatBN7.2
Rnor_6.01034,153,473 - 34,155,033NCBIRnor6.0
Rnor_6.015148,807 - 149,026NCBIRnor6.0
Rnor_5.015144,153 - 144,372UniSTSRnor5.0
Rnor_5.01033,937,376 - 33,938,936UniSTSRnor5.0
RGSC_v3.41034,070,951 - 34,072,511UniSTSRGSC3.4
RGSC_v3.415104,836 - 105,055UniSTSRGSC3.4
Celera154,440,546 - 4,440,765UniSTS
Celera1032,559,329 - 32,560,889UniSTS
Cytogenetic Map10q21UniSTS
Cytogenetic Map15p16UniSTS
RH139450  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.215187,567 - 187,729 (+)MAPPERmRatBN7.2
Rnor_6.015230,041 - 230,202NCBIRnor6.0
Rnor_5.015224,937 - 225,098UniSTSRnor5.0
RGSC_v3.415207,516 - 207,677UniSTSRGSC3.4
Celera154,360,649 - 4,360,810UniSTS
RH 3.4 Map1529.2UniSTS
Cytogenetic Map15p16UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354657Despr13Despair related QTL 130.0022locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)15129912054Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:104
Count of miRNA genes:67
Interacting mature miRNAs:68
Transcripts:ENSRNOT00000007828, ENSRNOT00000068181
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 20 6 4 4 66 35 34 11
Low 2 23 51 37 19 37 8 11 8 7 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007828   ⟹   ENSRNOP00000007828
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1576,021 - 187,837 (+)Ensembl
Rnor_6.0 Ensembl15120,372 - 228,977 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000099309   ⟹   ENSRNOP00000080089
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl15129,004 - 187,837 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000103743   ⟹   ENSRNOP00000081500
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1575,786 - 187,837 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000112381   ⟹   ENSRNOP00000096092
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1575,786 - 187,837 (+)Ensembl
RefSeq Acc Id: NM_001372003   ⟹   NP_001358932
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21575,786 - 187,839 (+)NCBI
RefSeq Acc Id: XM_039093224   ⟹   XP_038949152
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21575,786 - 209,735 (+)NCBI
RefSeq Acc Id: XM_039093225   ⟹   XP_038949153
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21575,786 - 209,735 (+)NCBI
RefSeq Acc Id: XM_039093226   ⟹   XP_038949154
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21575,875 - 209,735 (+)NCBI
RefSeq Acc Id: XM_039093227   ⟹   XP_038949155
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21575,874 - 172,461 (+)NCBI
RefSeq Acc Id: XM_039093228   ⟹   XP_038949156
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21575,874 - 170,554 (+)NCBI
Reference Sequences
RefSeq Acc Id: ENSRNOP00000007828   ⟸   ENSRNOT00000007828
RefSeq Acc Id: XP_038949152   ⟸   XM_039093224
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038949153   ⟸   XM_039093225
- Peptide Label: isoform X1
RefSeq Acc Id: NP_001358932   ⟸   NM_001372003
RefSeq Acc Id: XP_038949155   ⟸   XM_039093227
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038949156   ⟸   XM_039093228
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038949154   ⟸   XM_039093226
- Peptide Label: isoform X2
RefSeq Acc Id: ENSRNOP00000096092   ⟸   ENSRNOT00000112381
RefSeq Acc Id: ENSRNOP00000081500   ⟸   ENSRNOT00000103743
RefSeq Acc Id: ENSRNOP00000080089   ⟸   ENSRNOT00000099309
Protein Domains
Guanylate kinase-like   PDZ   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A3K3-F1-model_v2 AlphaFold D4A3K3 1-1815 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (MRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
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Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308753 AgrOrtholog
BioCyc Gene G2FUF-14615 BioCyc
Ensembl Genes ENSRNOG00000005783 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000007828 UniProtKB/TrEMBL
  ENSRNOP00000081500 ENTREZGENE
  ENSRNOP00000096092 ENTREZGENE
Ensembl Transcript ENSRNOT00000007828 UniProtKB/TrEMBL
  ENSRNOT00000103743 ENTREZGENE
  ENSRNOT00000112381 ENTREZGENE
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DLG5_SH3 UniProtKB/TrEMBL
  DUF622 UniProtKB/TrEMBL
  Guanylate_kin UniProtKB/TrEMBL
  Guanylate_kin/L-typ_Ca_channel UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
  SH3-like_dom UniProtKB/TrEMBL
  SH3_domain UniProtKB/TrEMBL
NCBI Gene 305645 ENTREZGENE
Pfam DUF622 UniProtKB/TrEMBL
  Guanylate_kin UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PhenoGen Dlg5 PhenoGen
PROSITE GUANYLATE_KINASE_2 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
SMART GuKc UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
Superfamily-SCOP PDZ UniProtKB/TrEMBL
  SH3 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt D4A3K3_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-06-01 Dlg5  discs large MAGUK scaffold protein 5  Dlg5  discs large homolog 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-01-27 Dlg5  discs large homolog 5  Dlg5  discs, large homolog 5 (Drosophila)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Dlg5  discs, large homolog 5 (Drosophila)   Dlg5_predicted  discs, large homolog 5 (Drosophila) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Dlg5_predicted  discs, large homolog 5 (Drosophila) (predicted)      Symbol and Name status set to approved 70820 APPROVED