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Gene: Nedd8 (NEDD8 ubiquitin like modifier) Rattus norvegicus
Symbol: Nedd8
Name: NEDD8 ubiquitin like modifier
Description: Predicted to have protein tag and ubiquitin protein ligase binding activity. Involved in protein neddylation and response to organic cyclic compound. Localizes to nucleus. Orthologous to human NEDD8 (NEDD8 ubiquitin like modifier); PARTICIPATES IN neddylation pathway; p53 signaling pathway; proteasome degradation pathway involving cullin-dependent ubiquitin ligases; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: CDK8; MGC105320; neddylin; neural precursor cell expressed, developmentally down-regulated 8; neural precursor cell expressed, developmentally down-regulated gene 8; ubiquitin-like protein Nedd8
Homo sapiens (human) : NEDD8 (NEDD8 ubiquitin like modifier)  HGNC  Alliance
Mus musculus (house mouse) : Nedd8 (neural precursor cell expressed, developmentally down-regulated gene 8)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nedd8 (NEDD8 ubiquitin like modifier)
Pan paniscus (bonobo/pygmy chimpanzee) : NEDD8 (NEDD8 ubiquitin like modifier)
Canis lupus familiaris (dog) : NEDD8 (NEDD8 ubiquitin like modifier)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nedd8 (NEDD8 ubiquitin like modifier)
Sus scrofa (pig) : NEDD8 (NEDD8 ubiquitin like modifier)
Chlorocebus sabaeus (African green monkey) : NEDD8 (NEDD8 ubiquitin like modifier)
Heterocephalus glaber (naked mole-rat) : Nedd8 (NEDD8 ubiquitin like modifier)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01534,340,607 - 34,352,673 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1534,340,607 - 34,352,673 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01538,230,806 - 38,242,650 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41533,797,457 - 33,820,624 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11533,813,156 - 33,836,123 (-)NCBI
Celera1528,729,741 - 28,741,968 (-)NCBICelera
Cytogenetic Map15p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Nedd8
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 3158
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2020-06-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.