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Gene: Esco2 (establishment of sister chromatid cohesion N-acetyltransferase 2) Rattus norvegicus
Symbol: Esco2
Name: establishment of sister chromatid cohesion N-acetyltransferase 2
RGD ID: 1593313
Description: Predicted to have lysine N-acetyltransferase activity, acting on acetyl phosphate as donor. Predicted to be involved in several processes, including hematopoietic progenitor cell differentiation; post-translational protein acetylation; and protein localization to chromatin. Predicted to localize to several cellular components, including Golgi apparatus; chromosome; and nucleoplasm. Human ortholog(s) of this gene implicated in Roberts syndrome and SC phocomelia syndrome. Orthologous to human ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; cobalt dichloride.
Type: protein-coding
RefSeq Status: MODEL
Also known as: establishment of cohesion 1 homolog 2; establishment of cohesion 1 homolog 2 (S. cerevisiae); LOC691979; N-acetyltransferase ESCO2; similar to N-acetyltransferase ESCO2 (Establishment of cohesion 1 homolog 2) (ECO1 homolog 2)
Related Pseudogenes: Esco2-ps1   Esco2-ps2  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01542,500,929 - 42,519,019 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1542,500,929 - 42,518,855 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01549,072,219 - 49,091,726 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41545,239,871 - 45,254,898 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1539,706,954 - 39,724,684 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Esco2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1593313
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.