Atp5pb (ATP synthase peripheral stalk-membrane subunit b) - Rat Genome Database

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Gene: Atp5pb (ATP synthase peripheral stalk-membrane subunit b) Rattus norvegicus
Analyze
Symbol: Atp5pb
Name: ATP synthase peripheral stalk-membrane subunit b
RGD ID: 620041
Description: Contributes to ATP hydrolysis activity. Involved in ATP metabolic process and cellular response to hypoxia. Part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Orthologous to human ATP5PB (ATP synthase peripheral stalk-membrane subunit b); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP synthase F(0) complex subunit B1, mitochondrial; ATP synthase subunit b; ATP synthase subunit b, mitochondrial; ATP synthase subunit b, mitochondrial-like; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1; ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1; Atp5f1; ATPase subunit b; LOC100911417
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22193,424,138 - 193,435,418 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2193,424,047 - 193,435,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2201,018,609 - 201,029,888 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02198,914,310 - 198,925,477 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02193,731,277 - 193,742,444 (-)NCBIRnor_WKY
Rnor_6.02208,566,385 - 208,577,147 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,408,890 - 208,420,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,566,385 - 208,577,146 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02227,987,601 - 227,998,363 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42201,195,390 - 201,206,585 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12201,158,143 - 201,169,339 (-)NCBI
Celera2186,126,257 - 186,137,862 (-)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Systematic Analysis of the Expression of the Mitochondrial ATP Synthase (Complex V) Subunits in Clear Cell Renal Cell Carcinoma. Br├╝ggemann M, etal., Transl Oncol. 2017 Aug;10(4):661-668. doi: 10.1016/j.tranon.2017.06.002. Epub 2017 Jun 30.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
5. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). Ko YH, etal., J Biol Chem. 2000 Oct 20;275(42):32931-9.
6. Distinct expression patterns in hepatitis B virus- and hepatitis C virus-infected hepatocellular carcinoma. Lee CF, etal., World J Gastroenterol. 2008 Oct 21;14(39):6072-7. doi: 10.3748/wjg.14.6072.
7. Identification of two proteins associated with mammalian ATP synthase. Meyer B, etal., Mol Cell Proteomics. 2007 Oct;6(10):1690-9. Epub 2007 Jun 17.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
12. GOA pipeline RGD automated data pipeline
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
15. cDNA cloning and sequencing for the import precursor of subunit B in H(+)-ATP synthase from rat mitochondria. Tsurumi C, etal., Biochem Biophys Res Commun 1990 May 31;169(1):136-42.
16. iTRAQ-Based Proteomic Analysis Reveals Recovery of Impaired Mitochondrial Function in Ischemic Myocardium by Shenmai Formula. Wang Y, etal., J Proteome Res. 2018 Feb 2;17(2):794-803. doi: 10.1021/acs.jproteome.7b00450. Epub 2018 Jan 23.
Additional References at PubMed
PMID:8889548   PMID:12110673   PMID:12865426   PMID:14651853   PMID:15489334   PMID:17634366   PMID:18614015   PMID:19946888   PMID:20833797   PMID:21630459   PMID:22926577   PMID:23376485  
PMID:24625528   PMID:29476059   PMID:32357304  


Genomics

Comparative Map Data
Atp5pb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22193,424,138 - 193,435,418 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2193,424,047 - 193,435,418 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2201,018,609 - 201,029,888 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.02198,914,310 - 198,925,477 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.02193,731,277 - 193,742,444 (-)NCBIRnor_WKY
Rnor_6.02208,566,385 - 208,577,147 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,408,890 - 208,420,163 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2208,566,385 - 208,577,146 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02227,987,601 - 227,998,363 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42201,195,390 - 201,206,585 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12201,158,143 - 201,169,339 (-)NCBI
Celera2186,126,257 - 186,137,862 (-)NCBICelera
Cytogenetic Map2q34NCBI
ATP5PB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381111,449,464 - 111,462,773 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl1111,448,864 - 111,462,773 (+)EnsemblGRCh38hg38GRCh38
GRCh371111,992,086 - 112,005,395 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361111,793,266 - 111,806,063 (+)NCBINCBI36Build 36hg18NCBI36
Build 341111,703,807 - 111,716,113NCBI
Celera1110,238,666 - 110,251,462 (+)NCBICelera
Cytogenetic Map1p13.2NCBI
HuRef1109,863,192 - 109,875,988 (+)NCBIHuRef
CHM1_11112,106,752 - 112,119,548 (+)NCBICHM1_1
T2T-CHM13v2.01111,464,148 - 111,477,456 (+)NCBIT2T-CHM13v2.0
Atp5pb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393105,850,014 - 105,866,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3105,850,014 - 105,867,415 (-)EnsemblGRCm39 Ensembl
GRCm383105,942,698 - 105,959,263 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3105,942,698 - 105,960,099 (-)EnsemblGRCm38mm10GRCm38
MGSCv373105,745,781 - 105,763,166 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363106,070,919 - 106,088,304 (-)NCBIMGSCv36mm8
Celera3108,133,284 - 108,150,668 (-)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map346.46NCBI
Atp5pb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543514,940,434 - 14,954,310 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543514,940,502 - 14,952,423 (+)NCBIChiLan1.0ChiLan1.0
ATP5PB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11126,224,308 - 126,236,596 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1126,224,725 - 126,235,897 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01114,110,749 - 114,122,715 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
LOC100688796
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11763,940,486 - 63,954,982 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,613,415 - 40,625,979 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,613,415 - 40,625,979 (-)NCBICanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1763,454,097 - 63,461,699 (-)NCBIDog10K_Boxer_Tasha
Atp5pb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505817,342,222 - 17,357,091 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936690120,572 - 135,509 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP5PB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4108,896,057 - 108,907,805 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14108,896,063 - 108,907,626 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24119,078,642 - 119,090,149 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP5PB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12022,150,488 - 22,162,740 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2022,150,239 - 22,162,312 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603836,316,725 - 36,328,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp5pb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247727,167,147 - 7,179,273 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247727,167,074 - 7,178,756 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp5pb
42 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2184114274202447032Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2185876309219753474Rat
1359031Bp275Blood pressure QTL 275arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2185876309219753474Rat
61458Bp10Blood pressure QTL 103.42arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1298083Bp158Blood pressure QTL 1582.62arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189020722215287351Rat
1331745Bp203Blood pressure QTL 2034.377arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2189599258218414891Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat

Markers in Region
AW531304  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22193,424,258 - 193,424,459 (+)MAPPERmRatBN7.2
Rnor_6.02208,566,506 - 208,566,706NCBIRnor6.0
Rnor_6.02208,409,011 - 208,409,211NCBIRnor6.0
Rnor_5.02227,987,722 - 227,987,922UniSTSRnor5.0
Rnor_5.02227,830,501 - 227,830,701UniSTSRnor5.0
RGSC_v3.42201,195,509 - 201,195,709UniSTSRGSC3.4
Celera2186,126,378 - 186,126,578UniSTS
RH 3.4 Map21372.0UniSTS
Cytogenetic Map2q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1
Below cutoff 4 37 28 17 17 17 4 5 74 31 39 6 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_134365 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC063808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK845764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209675 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214449 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ227239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ232356 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M35052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000021920   ⟹   ENSRNOP00000021920
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2193,424,047 - 193,435,349 (-)Ensembl
Rnor_6.0 Ensembl2208,408,890 - 208,420,163 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000075083   ⟹   ENSRNOP00000065147
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2193,424,047 - 193,431,820 (-)Ensembl
Rnor_6.0 Ensembl2208,566,385 - 208,577,146 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000075932
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,576,214 - 208,577,053 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000075982   ⟹   ENSRNOP00000068400
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2193,424,056 - 193,435,321 (-)Ensembl
Rnor_6.0 Ensembl2208,569,469 - 208,576,705 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076379
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,573,290 - 208,577,043 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076556   ⟹   ENSRNOP00000067965
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2193,424,676 - 193,435,418 (-)Ensembl
Rnor_6.0 Ensembl2208,411,969 - 208,419,722 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000076666
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,415,791 - 208,420,060 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077057
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2208,419,231 - 208,420,070 (-)Ensembl
RefSeq Acc Id: NM_134365   ⟹   NP_599192
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22193,424,138 - 193,435,418 (-)NCBI
Rnor_6.02208,566,385 - 208,577,147 (-)NCBI
Rnor_5.02227,987,601 - 227,998,363 (-)NCBI
RGSC_v3.42201,195,390 - 201,206,585 (-)RGD
Celera2186,126,257 - 186,137,862 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039101623   ⟹   XP_038957551
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22193,424,138 - 193,435,337 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_599192   ⟸   NM_134365
- Peptide Label: precursor
- UniProtKB: P19511 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068400   ⟸   ENSRNOT00000075982
RefSeq Acc Id: ENSRNOP00000065147   ⟸   ENSRNOT00000075083
RefSeq Acc Id: XP_038957551   ⟸   XM_039101623
- Peptide Label: isoform X1
RefSeq Acc Id: ENSRNOP00000067965   ⟸   ENSRNOT00000076556
RefSeq Acc Id: ENSRNOP00000021920   ⟸   ENSRNOT00000021920

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P19511-F1-model_v2 AlphaFold P19511 1-256 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691649
Promoter ID:EPDNEW_R2172
Type:initiation region
Name:LOC100911417_1
Description:ATP synthase subunit b, mitochondrial-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02208,577,078 - 208,577,138EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620041 AgrOrtholog
BioCyc Gene G2FUF-51717 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
Ensembl Genes ENSRNOG00000016000 Ensembl
  ENSRNOG00000046299 Ensembl
  ENSRNOG00000064742 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000021920 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000065147 ENTREZGENE
  ENSRNOP00000065147.2 UniProtKB/TrEMBL
  ENSRNOP00000067965.2 UniProtKB/TrEMBL
  ENSRNOP00000068400.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000021920 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOT00000075083 ENTREZGENE
  ENSRNOT00000075083.3 UniProtKB/TrEMBL
  ENSRNOT00000075982.2 UniProtKB/TrEMBL
  ENSRNOT00000076556.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6920021 IMAGE-MGC_LOAD
InterPro ATP_synth_Bsub_B/MI25 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP_synth_F0_suB UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:171375 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72698 IMAGE-MGC_LOAD
NCBI Gene 171375 ENTREZGENE
PANTHER PTHR12733 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Mt_ATP-synt_B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atp5pb PhenoGen
UniProt A0A096MJ25_RAT UniProtKB/TrEMBL
  A0A096MK68_RAT UniProtKB/TrEMBL
  A0A8L2QWG8_RAT UniProtKB/TrEMBL
  AT5F1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Atp5pb  ATP synthase peripheral stalk-membrane subunit b  LOC100911417  ATP synthase subunit b, mitochondrial-like  Data Merged 737654 PROVISIONAL
2017-11-30 Atp5pb  ATP synthase peripheral stalk-membrane subunit b  Atp5f1  ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911417  ATP synthase subunit b, mitochondrial-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-12-01 Atp5f1  ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1  Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-06-27 Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit B1  Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-02-26 Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Atp5f1  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit b, isoform 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_protein contains a mitochondrial import signal 631941