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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:82866 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-sertaconazole. A broad spectrum antifungal with added antipruritic and anti-inflammatory activity used (as its nitrate salt) for treatment of various skin infections.
Synonyms:exact_synonym: rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (+-)-1-(2,4-Dichloro-beta-((7-chlorobenzo(b)thien-3-yl)methoxy)phenethyl)imidazole;   (RS)-sertaconazole;   1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole;   7-Chloro-3-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl)benzo(b)thiophene;   Formula=C20H15Cl3N2OS;   rac-sertaconazole;   racemic sertaconazole;   sertaconazol;   sertaconazolum
 xref: CAS:99592-32-2;   DrugBank:DB01153;   HMDB:HMDB0015284;   KEGG:D06883
 xref_mesh: MESH:C061131
 xref: PMID:19925567;   PMID:20349685;   PMID:21746955;   PMID:21818511;   PMID:21968663;   PMID:23210976;   PMID:23296325;   PMID:23372210;   PMID:23441833;   PMID:23470235;   PMID:23546772;   PMID:23566144;   PMID:23715821;   PMID:23829055;   PMID:24171300;   PMID:24249897;   PMID:24249898;   PMID:24511475;   PMID:24791343;   PMID:24845480;   PMID:24881281;   PMID:24909149;   PMID:24953450;   Reaxys:5385663

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sertaconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO sertaconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19757
    chemical entity 19755
      chemical substance 14004
        mixture 13298
          racemate 11728
            sertaconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19757
    subatomic particle 19755
      composite particle 19755
        hadron 19755
          baryon 19755
            nucleon 19755
              atomic nucleus 19755
                atom 19755
                  main group element atom 19703
                    p-block element atom 19703
                      carbon group element atom 19649
                        carbon atom 19645
                          organic molecular entity 19645
                            organic molecule 19604
                              organic cyclic compound 19407
                                organic heterocyclic compound 18772
                                  heteroarene 16879
                                    monocyclic heteroarene 14242
                                      azole 13600
                                        diazole 8634
                                          imidazoles 7735
                                            imidazole antifungal agent 1300
                                              imidazole antifungal drug 830
                                                arasertaconazole 1
                                                  sertaconazole 1
paths to the root