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ONTOLOGY REPORT - ANNOTATIONS


Term:sertaconazole
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Accession:CHEBI:82866 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-sertaconazole. A broad spectrum antifungal with added antipruritic and anti-inflammatory activity used (as its nitrate salt) for treatment of various skin infections.
Synonyms:exact_synonym: rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (+-)-1-(2,4-Dichloro-beta-((7-chlorobenzo(b)thien-3-yl)methoxy)phenethyl)imidazole;   (RS)-sertaconazole;   1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole;   7-Chloro-3-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl)benzo(b)thiophene;   Formula=C20H15Cl3N2OS;   rac-sertaconazole;   racemic sertaconazole;   sertaconazol;   sertaconazolum
 xref: CAS:99592-32-2 "ChemIDplus";   CAS:99592-32-2 "KEGG DRUG";   DrugBank:DB01153;   HMDB:HMDB0015284;   KEGG:D06883
 xref_mesh: MESH:C061131
 xref: PMID:19925567 "Europe PMC";   PMID:20349685 "Europe PMC";   PMID:21746955 "Europe PMC";   PMID:21818511 "Europe PMC";   PMID:21968663 "Europe PMC";   PMID:23210976 "Europe PMC";   PMID:23296325 "Europe PMC";   PMID:23372210 "Europe PMC";   PMID:23441833 "Europe PMC";   PMID:23470235 "Europe PMC";   PMID:23546772 "Europe PMC";   PMID:23566144 "Europe PMC";   PMID:23715821 "Europe PMC";   PMID:23829055 "Europe PMC";   PMID:24171300 "Europe PMC";   PMID:24249897 "Europe PMC";   PMID:24249898 "Europe PMC";   PMID:24511475 "Europe PMC";   PMID:24791343 "Europe PMC";   PMID:24845480 "Europe PMC";   PMID:24881281 "Europe PMC";   PMID:24909149 "Europe PMC";   PMID:24953450 "Europe PMC";   Reaxys:5385663 "Reaxys"


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sertaconazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19669
    chemical entity 19667
      chemical substance 10725
        mixture 9929
          racemate 8658
            sertaconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19669
    subatomic particle 19665
      composite particle 19665
        hadron 19665
          baryon 19665
            nucleon 19665
              atomic nucleus 19665
                atom 19665
                  main group element atom 19545
                    p-block element atom 19545
                      carbon group element atom 19428
                        carbon atom 19420
                          organic molecular entity 19420
                            organic molecule 19343
                              organic cyclic compound 19093
                                organic heterocyclic compound 18157
                                  heteroarene 15146
                                    monocyclic heteroarene 11614
                                      azole 10473
                                        diazole 8040
                                          imidazoles 7591
                                            imidazole antifungal agent 1230
                                              imidazole antifungal drug 763
                                                arasertaconazole 1
                                                  sertaconazole 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.