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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at The data is made available under the Creative Commons License (CC BY 3.0, For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

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Accession:CHEBI:82866 term browser browse the term
Definition:A racemate comprising equimolar amounts of (R)- and (S)-sertaconazole. A broad spectrum antifungal with added antipruritic and anti-inflammatory activity used (as its nitrate salt) for treatment of various skin infections.
Synonyms:exact_synonym: rac-1-{2-[(7-chloro-1-benzothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
 related_synonym: (+-)-1-(2,4-Dichloro-beta-((7-chlorobenzo(b)thien-3-yl)methoxy)phenethyl)imidazole;   (RS)-sertaconazole;   1-(2-((7-Chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-1H-imidazole;   7-Chloro-3-(1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethoxy-methyl)benzo(b)thiophene;   Formula=C20H15Cl3N2OS;   rac-sertaconazole;   racemic sertaconazole;   sertaconazol;   sertaconazolum
 xref: CAS:99592-32-2;   DrugBank:DB01153;   HMDB:HMDB0015284;   KEGG:D06883
 xref_mesh: MESH:C061131
 xref: PMID:19925567;   PMID:20349685;   PMID:21746955;   PMID:21818511;   PMID:21968663;   PMID:23210976;   PMID:23296325;   PMID:23372210;   PMID:23441833;   PMID:23470235;   PMID:23546772;   PMID:23566144;   PMID:23715821;   PMID:23829055;   PMID:24171300;   PMID:24249897;   PMID:24249898;   PMID:24511475;   PMID:24791343;   PMID:24845480;   PMID:24881281;   PMID:24909149;   PMID:24953450;   Reaxys:5385663

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sertaconazole term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnh2 potassium voltage-gated channel subfamily H member 2 decreases activity ISO sertaconazole results in decreased activity of KCNH2 protein CTD PMID:28551711 NCBI chr 4:10,826,834...10,859,009
Ensembl chr 4:10,826,928...10,859,008
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Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    chemical entity 19812
      chemical substance 12981
        mixture 12153
          racemate 10095
            sertaconazole 1
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19811
      composite particle 19811
        hadron 19811
          baryon 19811
            nucleon 19811
              atomic nucleus 19811
                atom 19811
                  main group element atom 19708
                    p-block element atom 19708
                      carbon group element atom 19630
                        carbon atom 19620
                          organic molecular entity 19620
                            organic molecule 19560
                              organic cyclic compound 19351
                                organic heterocyclic compound 18582
                                  heteroarene 16534
                                    monocyclic heteroarene 13436
                                      azole 12624
                                        diazole 8394
                                          imidazoles 7688
                                            imidazole antifungal agent 1303
                                              imidazole antifungal drug 827
                                                arasertaconazole 1
                                                  sertaconazole 1
paths to the root