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Gene: Cr2 (complement C3d receptor 2) Rattus norvegicus
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Symbol: Cr2
Name: complement C3d receptor 2
Description: Predicted to have several functions, including DNA binding activity; complement receptor activity; and protein homodimerization activity. Predicted to be involved in B cell differentiation and B cell proliferation. Predicted to localize to the external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in common variable immunodeficiency and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2); PARTICIPATES IN B cell receptor signaling pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH bisphenol A; 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 4,4'-diaminodiphenylmethane (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cd21; complement component (3d/Epstein Barr virus) receptor 2; complement component 3d receptor 2; complement receptor 2; complement receptor type 2
Orthologs:
Homo sapiens (human) : CR2 (complement C3d receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Cr2 (complement receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cr2 (complement C3d receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CR2 (complement C3d receptor 2)
Canis lupus familiaris (dog) : CR2 (complement C3d receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.013113,890,274 - 113,927,824 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.013118,580,480 - 118,618,039 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413111,078,338 - 111,113,667 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113111,281,069 - 111,300,233 (-)NCBI
Celera13106,107,601 - 106,138,227 (-)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Cr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310065
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.