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Gene: Cr2 (complement C3d receptor 2) Rattus norvegicus
Symbol: Cr2
Name: complement C3d receptor 2
RGD ID: 1310065
Description: Predicted to have several functions, including complement binding activity; complement receptor activity; and protein homodimerization activity. Predicted to be involved in several processes, including B cell activation; complement activation, alternative pathway; and skeletal system development. Predicted to localize to external side of plasma membrane and receptor complex. Human ortholog(s) of this gene implicated in common variable immunodeficiency and systemic lupus erythematosus. Orthologous to human CR2 (complement C3d receptor 2); PARTICIPATES IN B cell receptor signaling pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; 1,2-dichloroethane (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Cd21; complement component (3d/Epstein Barr virus) receptor 2; complement component 3d receptor 2; complement receptor 2; complement receptor type 2
Homo sapiens (human) : CR2 (complement C3d receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Cr2 (complement receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cr2 (complement C3d receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CR2 (complement C3d receptor 2)
Canis lupus familiaris (dog) : CR2 (complement C3d receptor 2)
Chlorocebus sabaeus (African green monkey) : CR2 (complement C3d receptor 2)
Heterocephalus glaber (naked mole-rat) : Cr2 (complement C3d receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.013113,890,274 - 113,927,824 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13113,890,272 - 113,927,877 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013118,580,480 - 118,618,039 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.413111,078,338 - 111,113,667 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.113111,281,069 - 111,300,233 (-)NCBI
Celera13106,107,601 - 106,138,227 (-)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
More on Cr2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1310065
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.