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Gene: Atp6v0c (ATPase H+ transporting V0 subunit C) Rattus norvegicus
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Symbol: Atp6v0c
Name: ATPase H+ transporting V0 subunit C
RGD ID: 621394
Description: Predicted to have proton-transporting ATPase activity, rotational mechanism and ubiquitin protein ligase binding activity. Involved in negative regulation of autophagic cell death and positive regulation of ERK1 and ERK2 cascade. Localizes to Golgi apparatus; lysosome; and synaptic vesicle. Human ortholog(s) of this gene implicated in thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c); PARTICIPATES IN oxidative phosphorylation pathway; phagocytosis pathway; rheumatoid arthritis pathway; INTERACTS WITH 2,4-dinitrotoluene; ammonium chloride; amphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Atp6c; Atp6l; ATPase, H transporting, lysosomal V0 subunit c; ATPase, H+ transporting, lysosomal (vacuolar proton pump) 16 kDa; ATPase, H+ transporting, lysosomal (vacuolar proton pump), subunit C; ATPase, H+ transporting, lysosomal 1; ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c; ATPase, H+ transporting, lysosomal V0 subunit C; ATPase, H+ transporting, V0 subunit C; V-ATPase 16 kDa proteolipid subunit; V-type proton ATPase 16 kDa proteolipid subunit; vacuolar proton pump 16 kDa proteolipid subunit
Orthologs:
Homo sapiens (human) : ATP6V0C (ATPase H+ transporting V0 subunit c)  HGNC  Alliance
Mus musculus (house mouse) : Atp6v0c (ATPase, H+ transporting, lysosomal V0 subunit C)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp6v0c (ATPase H+ transporting V0 subunit c)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Canis lupus familiaris (dog) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp6v0c (ATPase H+ transporting V0 subunit c)
Sus scrofa (pig) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Chlorocebus sabaeus (African green monkey) : ATP6V0C (ATPase H+ transporting V0 subunit c)
Heterocephalus glaber (naked mole-rat) : Atp6v0c (ATPase H+ transporting V0 subunit c)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01013,537,031 - 13,543,407 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1013,537,033 - 13,542,077 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01013,352,991 - 13,359,367 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41013,415,671 - 13,420,715 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11013,415,670 - 13,420,715 (-)NCBI
Celera1012,882,252 - 12,887,296 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Atp6v0c
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621394
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.