Gene: Gnai1 (G protein subunit alpha i1) Rattus norvegicus
Symbol: Gnai1
Name: G protein subunit alpha i1
Description: ENCODES a protein that exhibits G-protein coupled receptor binding; G-protein coupled serotonin receptor binding; GDP binding; INVOLVED IN cellular response to forskolin; G-protein coupled receptor signaling pathway; negative regulation of synaptic transmission; PARTICIPATES IN G protein mediated signaling pathway via Galphai family; orexin/hypocretin signaling pathway via orexin/hypocretin receptor 2; acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family; ASSOCIATED WITH Amnesia (ortholog); Pleomorphic Xanthoastrocytoma (ortholog); Seizures (ortholog); FOUND IN centrosome; cytoplasm; membrane; INTERACTS WITH 2-methoxyethanol; 6-propyl-2-thiouracil; aflatoxin B1
Type: protein-coding
Also known as: adenylate cyclase-inhibiting G alpha protein; BPGTPB; guanine nucleotide binding protein (G protein), alpha inhibiting 1; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide binding protein, alpha inhibiting 1; guanine nucleotide-binding protein G(i) subunit alpha-1; guanine nucleotide-binding protein G(i), alpha-1 subunit
Homo sapiens (human) : GNAI1 (G protein subunit alpha i1)  HGNC  Alliance
Mus musculus (house mouse) : Gnai1 (guanine nucleotide binding protein (G protein), alpha inhibiting 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnai1 (G protein subunit alpha i1)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAI1 (G protein subunit alpha i1)
Canis lupus familiaris (dog) : GNAI1 (G protein subunit alpha i1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnai1 (G protein subunit alpha i1)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0413,405,136 - 13,486,866 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0413,388,073 - 13,470,279 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4412,465,089 - 12,495,028 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1412,465,088 - 12,495,028 (+)NCBI
Celera412,346,868 - 12,428,695 (+)NCBICelera
Cytogenetic Map4q11NCBI
RH 3.4 Map449.5RGD
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gnai1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 2713
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2018-03-13
Status: ACTIVE