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Gene: GNAI1 (G protein subunit alpha i1) Homo sapiens
Symbol: GNAI1
Name: G protein subunit alpha i1
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; magnesium ion binding activity; and purine ribonucleoside binding activity. Involved in cell division; positive regulation of protein localization to cell cortex; and regulation of mitotic spindle organization. Localizes to several cellular components, including cell cortex region; centrosome; and midbody.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenylate cyclase-inhibiting G alpha protein; Gi; Gi1 protein alpha subunit; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide-binding protein G(i) subunit alpha-1
Mus musculus (house mouse) : Gnai1 (guanine nucleotide binding protein (G protein), alpha inhibiting 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Gnai1 (G protein subunit alpha i1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gnai1 (G protein subunit alpha i1)
Pan paniscus (bonobo/pygmy chimpanzee) : GNAI1 (G protein subunit alpha i1)
Canis lupus familiaris (dog) : GNAI1 (G protein subunit alpha i1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gnai1 (G protein subunit alpha i1)
Sus scrofa (pig) : GNAI1 (G protein subunit alpha i1)
Chlorocebus sabaeus (African green monkey) : GNAI1 (G protein subunit alpha i1)
Heterocephalus glaber (naked mole-rat) : Gnai1 (G protein subunit alpha i1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl779,768,028 - 80,226,181 (+)EnsemblGRCh38hg38GRCh38
GRCh38780,134,831 - 80,226,181 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37779,764,140 - 79,848,725 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36779,602,076 - 79,686,661 (+)NCBINCBI36hg18NCBI36
Build 34779,408,790 - 79,493,376NCBI
Celera774,464,804 - 74,549,389 (+)NCBI
Cytogenetic Map7q21.11NCBI
HuRef774,366,659 - 74,451,137 (+)NCBIHuRef
CHM1_1779,694,209 - 79,778,804 (+)NCBICHM1_1
CRA_TCAGchr7v2779,095,649 - 79,180,223 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GNAI1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730824
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.