Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2713
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gnai1
Name: G protein subunit alpha i1
Acc ID: CHEBI:4636
Term: diphenhydramine
Definition: An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
Chemical ID: MESH:D004155
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gnai1increases response to substanceISORGD:7308256480464CTDGNAI1 results in increased susceptibility to DiphenhydraminePMID:14614911
Go Back to source page   Continue to Ontology report