GNAI1 (G protein subunit alpha i1) - Rat Genome Database

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Gene: GNAI1 (G protein subunit alpha i1) Sus scrofa
Analyze
Symbol: GNAI1
Name: G protein subunit alpha i1
RGD ID: 13880638
Description: ENCODES a protein that exhibits G protein-coupled serotonin receptor binding (ortholog); GDP binding (ortholog); GTPase activating protein binding (ortholog); INVOLVED IN cellular response to forskolin (ortholog); G protein-coupled receptor signaling pathway (ortholog); negative regulation of synaptic transmission (ortholog); PARTICIPATES IN acetylcholine signaling pathway via muscarinic acetylcholine receptors engaging G alphai protein family; endothelin signaling pathway; epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH amnestic disorder (ortholog); epilepsy (ortholog); Neurodevelopmental Disorders (ortholog); FOUND IN cytoplasm (ortholog); membrane (ortholog); membrane raft (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: GBI1; Gi-alpha-1 protein; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1; guanine nucleotide-binding protein G(i) subunit alpha-1
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9100,182,757 - 100,272,625 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19100,187,878 - 100,272,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29110,559,455 - 110,592,579 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:1899094  


Genomics

Comparative Map Data
GNAI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9100,182,757 - 100,272,625 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19100,187,878 - 100,272,274 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29110,559,455 - 110,592,579 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GNAI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl779,768,028 - 80,226,181 (+)EnsemblGRCh38hg38GRCh38
GRCh38780,134,831 - 80,226,181 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37779,764,147 - 79,855,497 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36779,602,076 - 79,686,661 (+)NCBINCBI36hg18NCBI36
Build 34779,408,790 - 79,493,376NCBI
Celera774,464,804 - 74,549,389 (+)NCBI
Cytogenetic Map7q21.11NCBI
HuRef774,366,659 - 74,451,137 (+)NCBIHuRef
CHM1_1779,694,209 - 79,778,804 (+)NCBICHM1_1
CRA_TCAGchr7v2779,095,649 - 79,180,223 (+)NCBI
Gnai1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39518,470,133 - 18,565,411 (-)NCBIGRCm39mm39
GRCm39 Ensembl518,470,133 - 18,565,353 (-)Ensembl
GRCm38518,265,135 - 18,360,413 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl518,265,135 - 18,360,355 (-)EnsemblGRCm38mm10GRCm38
MGSCv37517,770,953 - 17,866,231 (-)NCBIGRCm37mm9NCBIm37
MGSCv36517,776,959 - 17,872,237 (-)NCBImm8
Celera515,230,415 - 15,321,001 (-)NCBICelera
Cytogenetic Map5A3NCBI
cM Map58.16NCBI
Gnai1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2416,813,941 - 16,898,111 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl416,814,001 - 16,896,417 (+)Ensembl
Rnor_6.0413,405,136 - 13,486,866 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl413,405,136 - 13,485,883 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0413,388,073 - 13,470,279 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4412,465,089 - 12,495,028 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1412,465,088 - 12,495,028 (+)NCBI
Celera412,346,868 - 12,428,695 (+)NCBICelera
RH 3.4 Map449.5RGD
Cytogenetic Map4q11NCBI
Gnai1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554105,388,184 - 5,467,022 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554105,388,184 - 5,467,022 (-)NCBIChiLan1.0ChiLan1.0
GNAI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1785,766,875 - 85,851,283 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl785,812,249 - 85,851,283 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0772,102,937 - 72,188,124 (+)NCBIMhudiblu_PPA_v0panPan3
GNAI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11819,924,381 - 19,952,956 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1819,924,235 - 19,951,244 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1819,541,512 - 19,621,800 (+)NCBI
ROS_Cfam_1.01820,317,597 - 20,397,882 (+)NCBI
UMICH_Zoey_3.11819,944,408 - 20,024,681 (+)NCBI
UNSW_CanFamBas_1.01819,496,206 - 19,576,670 (+)NCBI
UU_Cfam_GSD_1.01820,152,237 - 20,232,734 (+)NCBI
Gnai1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511861,784,125 - 61,867,169 (+)NCBI
SpeTri2.0NW_004936810353,405 - 435,087 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNAI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12168,687,809 - 68,770,415 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2168,687,307 - 68,770,360 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604235,173,786 - 35,256,485 (+)NCBIVero_WHO_p1.0
Gnai1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473928,995,173 - 29,074,354 (+)NCBIHetGla_female_1.0hetGla2


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 5 3 2 22 1 1
Low 5 4 3 2 1 1 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000016782   ⟹   ENSSSCP00000016334
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9100,182,757 - 100,272,226 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000069487   ⟹   ENSSSCP00000062206
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9100,189,835 - 100,272,625 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000082569   ⟹   ENSSSCP00000065703
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9100,188,634 - 100,271,394 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000089406   ⟹   ENSSSCP00000071100
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl9100,182,757 - 100,272,620 (-)Ensembl
RefSeq Acc Id: XM_021063494   ⟹   XP_020919153
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.19100,187,878 - 100,272,274 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001116587 (Get FASTA)   NCBI Sequence Viewer  
  XP_020919153 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA31052 (Get FASTA)   NCBI Sequence Viewer  
  AAA82036 (Get FASTA)   NCBI Sequence Viewer  
  ABI97193 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_020919153   ⟸   XM_021063494
- Sequence:
RefSeq Acc Id: ENSSSCP00000071100   ⟸   ENSSSCT00000089406
RefSeq Acc Id: ENSSSCP00000016334   ⟸   ENSSSCT00000016782
RefSeq Acc Id: ENSSSCP00000062206   ⟸   ENSSSCT00000069487
RefSeq Acc Id: ENSSSCP00000065703   ⟸   ENSSSCT00000082569


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000015407 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070000597 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000016334 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000062206 UniProtKB/TrEMBL
  ENSSSCP00000065703 UniProtKB/TrEMBL
  ENSSSCP00000071100 UniProtKB/TrEMBL
  ENSSSCP00070001000 UniProtKB/TrEMBL
  ENSSSCP00070001013 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000016782 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000069487 UniProtKB/TrEMBL
  ENSSSCT00000082569 UniProtKB/TrEMBL
  ENSSSCT00000089406 UniProtKB/TrEMBL
  ENSSSCT00070001135 UniProtKB/TrEMBL
  ENSSSCT00070001148 UniProtKB/TrEMBL
Gene3D-CATH 1.10.400.10 UniProtKB/TrEMBL
InterPro Gprotein_alpha_I UniProtKB/TrEMBL
  Gprotein_alpha_su UniProtKB/TrEMBL
  GproteinA_insert UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene GNAI1 ENTREZGENE
PANTHER PTHR10218 UniProtKB/TrEMBL
Pfam G-alpha UniProtKB/TrEMBL
PRINTS GPROTEINA UniProtKB/TrEMBL
  GPROTEINAI UniProtKB/TrEMBL
PROSITE G_ALPHA UniProtKB/TrEMBL
SMART G_alpha UniProtKB/TrEMBL
Superfamily-SCOP SSF47895 UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A4X1SFJ7_PIG UniProtKB/TrEMBL
  A0A4X1SGN2_PIG UniProtKB/TrEMBL
  A0A5G2QDJ3_PIG UniProtKB/TrEMBL
  A0A5G2QM73_PIG UniProtKB/TrEMBL
  A0A5G2RAE3_PIG UniProtKB/TrEMBL
  F1SB90_PIG UniProtKB/TrEMBL
  Q06AS7_PIG UniProtKB/TrEMBL
VGNC ID VGNC:88521 ENTREZGENE