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Accession:CHEBI:7825 term browser browse the term
Definition:An oxime O-ether that is the 2,4-dichlorobenzyl ether of the oxime obtained by formal condensation of hydroxylamine with the carbonyl group of acetopnenone in which the phenyl group is substituted by chlorines at positions 2 and 4, and in which one of the hydrogens of the methyl group is replaced by a 1H-imidazol-1-yl group. An antifungal agent, it is used (generally as the nitrate salt) in creams and powders for the topical treatment of fungal skin infections.
Synonyms:exact_synonym: (1Z)-N-[(2,4-dichlorobenzyl)oxy]-1-(2,4-dichlorophenyl)-2-(1H-imidazol-1-yl)ethanimine
 related_synonym: 2',4'-Dichloro-2-imidazol-1-ylacetophenone (Z)-[O-(2,4-dichlorobenzyl)oxime];   Formula=C18H13Cl4N3O;   InChI=1S/C18H13Cl4N3O/c19-13-2-1-12(16(21)7-13)10-26-24-18(9-25-6-5-23-11-25)15-4-3-14(20)8-17(15)22/h1-8,11H,9-10H2/b24-18+;   InChIKey=QRJJEGAJXVEBNE-HKOYGPOVSA-N;   Ro 13-8996;   SMILES=Clc1ccc(CO\\N=C(/Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1;   oxiconazol;   oxiconazolum
 xref: CAS:64211-45-6 "ChemIDplus";   CAS:64211-45-6 "KEGG COMPOUND";   DrugBank:DB00239;   Drug_Central:3408 "DrugCentral";   HMDB:HMDB0014384;   KEGG:C08074;   KEGG:D08313
 xref_mesh: MESH:C022155
 xref: PMID:15797782 "Europe PMC";   PMID:2029718 "Europe PMC";   PMID:22569007 "Europe PMC";   PMID:23482479 "Europe PMC";   PMID:2793313 "Europe PMC";   PMID:7037014 "Europe PMC";   Patent:US4550175;   Reaxys:6004213 "Reaxys";   Wikipedia:Oxiconazole
 cyclic_relationship: is_conjugate_base_of CHEBI:77698

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oxiconazole term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 JBrowse link 8 58,744,849 58,772,408 RGD:6480464
G Gstp1 glutathione S-transferase pi 1 JBrowse link 1 219,291,679 219,294,147 RGD:6480464
G Kcnh2 potassium voltage-gated channel subfamily H member 2 JBrowse link 4 7,355,066 7,387,282 RGD:6480464
G Ncoa1 nuclear receptor coactivator 1 JBrowse link 6 28,677,563 28,931,844 RGD:6480464
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 JBrowse link 11 65,022,100 65,058,546 RGD:6480464
G Slc22a2 solute carrier family 22 member 2 JBrowse link 1 48,318,025 48,360,219 RGD:6480464

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  CHEBI ontology 19654
    role 19598
      application 19220
        pharmaceutical 19081
          drug 19081
            antiinfective agent 12871
              oxiconazole 6
Path 2
Term Annotations click to browse term
  CHEBI ontology 19654
    subatomic particle 19650
      composite particle 19650
        hadron 19650
          baryon 19650
            nucleon 19650
              atomic nucleus 19650
                atom 19650
                  main group element atom 19531
                    p-block element atom 19531
                      carbon group element atom 19413
                        carbon atom 19405
                          organic molecular entity 19405
                            organic molecule 19327
                              organic cyclic compound 19076
                                organic heterocyclic compound 18151
                                  heteroarene 15151
                                    monocyclic heteroarene 11614
                                      azole 10473
                                        diazole 8041
                                          imidazoles 7591
                                            imidazole antifungal agent 1231
                                              imidazole antifungal drug 763
                                                oxiconazole 6
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