Dnase1l1 (deoxyribonuclease 1-like 1) - Rat Genome Database

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Gene: Dnase1l1 (deoxyribonuclease 1-like 1) Rattus norvegicus
Analyze
Symbol: Dnase1l1
Name: deoxyribonuclease 1-like 1
RGD ID: 1359588
Description: Predicted to enable DNA binding activity and deoxyribonuclease I activity. Predicted to be involved in DNA catabolic process, endonucleolytic. Predicted to be located in endoplasmic reticulum. Predicted to be active in nucleus. Orthologous to human DNASE1L1 (deoxyribonuclease 1 like 1); INTERACTS WITH all-trans-retinoic acid; bisphenol A; tetrachloromethane.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: deoxyribonuclease I-like 1; deoxyribonuclease-1-like 1; DNase I-like 1; DNase X; LOC363522; similar to RIKEN cDNA 2310005K03
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X152,056,942 - 152,065,518 (-)NCBI
Rnor_6.0 EnsemblX156,429,585 - 156,438,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X156,429,521 - 156,438,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,169,678 - 152,178,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,327,966 - 160,336,447 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X160,404,391 - 160,412,828 (+)NCBI
Celera1135,831,332 - 135,839,813 (+)NCBICelera
Cytogenetic MapXq37NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
endoplasmic reticulum  (IEA,ISO)
nucleus  (IBA)

Molecular Function

References

Additional References at PubMed
PMID:16107205   PMID:23376485  


Genomics

Comparative Map Data
Dnase1l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X152,056,942 - 152,065,518 (-)NCBI
Rnor_6.0 EnsemblX156,429,585 - 156,438,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X156,429,521 - 156,438,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,169,678 - 152,178,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,327,966 - 160,336,447 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X160,404,391 - 160,412,828 (+)NCBI
Celera1135,831,332 - 135,839,813 (+)NCBICelera
Cytogenetic MapXq37NCBI
DNASE1L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX154,401,236 - 154,412,112 (-)EnsemblGRCh38hg38GRCh38
GRCh38X154,401,236 - 154,412,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,629,577 - 153,640,438 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,282,773 - 153,293,621 (-)NCBINCBI36hg18NCBI36
Build 34X153,150,425 - 153,158,422NCBI
CeleraX153,790,635 - 153,801,484 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,206,968 - 142,217,816 (-)NCBIHuRef
CHM1_1X153,541,222 - 153,552,074 (-)NCBICHM1_1
Dnase1l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,316,823 - 73,325,939 (-)NCBIGRCm39mm39
GRCm39 EnsemblX73,316,823 - 73,325,943 (-)Ensembl
GRCm38X74,273,217 - 74,282,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,273,217 - 74,282,337 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X71,518,556 - 71,527,672 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,525,938 - 70,534,454 (-)NCBImm8
CeleraX65,526,994 - 65,536,124 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.94NCBI
Dnase1l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580907,582 - 914,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580907,056 - 913,604 (-)NCBIChiLan1.0ChiLan1.0
DNASE1L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X153,712,050 - 153,725,868 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,712,054 - 153,725,868 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X143,842,920 - 143,851,795 (-)NCBIMhudiblu_PPA_v0panPan3
DNASE1L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,101,992 - 122,109,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,101,992 - 122,109,165 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,243,686 - 125,250,933 (-)NCBI
UMICH_Zoey_3.1X121,012,760 - 121,020,007 (-)NCBI
UNSW_CanFamBas_1.0X123,527,626 - 123,534,873 (-)NCBI
UU_Cfam_GSD_1.0X123,289,507 - 123,296,773 (-)NCBI
Dnase1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,413,626 - 119,420,791 (-)NCBI
SpeTri2.0NW_0049368091,151,312 - 1,159,017 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNASE1L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,931,408 - 124,939,965 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,931,410 - 124,937,569 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DNASE1L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606566,628,194 - 66,636,944 (-)NCBI
Dnase1l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624946858,638 - 869,859 (-)NCBI

Position Markers
RH137735  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,059,445 - 152,059,635 (-)MAPPER
Rnor_6.0X156,435,373 - 156,435,562NCBIRnor6.0
Rnor_5.01152,175,520 - 152,175,709UniSTSRnor5.0
RGSC_v3.4X160,333,754 - 160,333,943UniSTSRGSC3.4
Celera1135,837,120 - 135,837,309UniSTS
Cytogenetic MapXq37UniSTS
RH139827  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X152,056,983 - 152,057,167 (-)MAPPER
Rnor_6.0X156,437,841 - 156,438,024NCBIRnor6.0
Rnor_5.01152,177,988 - 152,178,171UniSTSRnor5.0
RGSC_v3.4X160,336,222 - 160,336,405UniSTSRGSC3.4
Celera1135,839,588 - 135,839,771UniSTS
Cytogenetic MapXq37UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X44320616158345622Rat
634346Insul4Insulin level QTL 40blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)X134627816159970021Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X118715462159970021Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:36
Interacting mature miRNAs:39
Transcripts:ENSRNOT00000056285
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 41 25 19 25 8 11 54 35 34 11 8
Low 8 16 16 16 20 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000077322   ⟹   ENSRNOP00000073264
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX156,429,630 - 156,438,066 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000083203   ⟹   ENSRNOP00000073157
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX156,429,585 - 156,438,066 (+)Ensembl
RefSeq Acc Id: NM_001014223   ⟹   NP_001014245
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,056,942 - 152,065,424 (-)NCBI
Rnor_6.0X156,429,585 - 156,438,066 (+)NCBI
Rnor_5.01152,169,678 - 152,178,213 (+)NCBI
RGSC_v3.4X160,327,966 - 160,336,447 (+)RGD
Celera1135,831,332 - 135,839,813 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006229602   ⟹   XP_006229664
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,056,942 - 152,065,518 (-)NCBI
Rnor_6.0X156,429,521 - 156,438,066 (+)NCBI
Rnor_5.01152,169,678 - 152,178,213 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099925   ⟹   XP_038955853
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,056,942 - 152,065,465 (-)NCBI
RefSeq Acc Id: XM_039099926   ⟹   XP_038955854
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,056,942 - 152,065,518 (-)NCBI
RefSeq Acc Id: XM_039099927   ⟹   XP_038955855
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,056,942 - 152,065,469 (-)NCBI
RefSeq Acc Id: XM_039099928   ⟹   XP_038955856
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,056,942 - 152,059,829 (-)NCBI
RefSeq Acc Id: XM_039099929   ⟹   XP_038955857
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2X152,056,942 - 152,060,276 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001014245   ⟸   NM_001014223
- Peptide Label: precursor
- UniProtKB: Q2QDE7 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006229664   ⟸   XM_006229602
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000073264   ⟸   ENSRNOT00000077322
RefSeq Acc Id: ENSRNOP00000073157   ⟸   ENSRNOT00000083203
RefSeq Acc Id: XP_038955854   ⟸   XM_039099926
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038955855   ⟸   XM_039099927
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038955853   ⟸   XM_039099925
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038955857   ⟸   XM_039099929
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038955856   ⟸   XM_039099928
- Peptide Label: isoform X5
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13702047
Promoter ID:EPDNEW_R12571
Type:initiation region
Name:Dnase1l1_1
Description:deoxyribonuclease 1-like 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X156,429,580 - 156,429,640EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359588 AgrOrtholog
Ensembl Genes ENSRNOG00000055641 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000073157 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOP00000073264 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000077322 UniProtKB/TrEMBL
  ENSRNOT00000083203 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.60.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7122158 IMAGE-MGC_LOAD
InterPro Deoxyribonuclease-1_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNase_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNASE_I_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endo/exonuclease/phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:363522 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94028 IMAGE-MGC_LOAD
NCBI Gene 363522 ENTREZGENE
Pfam Exo_endo_phos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dnase1l1 PhenoGen
PIRSF DNase_I_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS DNASEI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DNASE_I_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNASE_I_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DNaseIc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56219 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt DNSL1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q6AYF0_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2006-03-30 Dnase1l1  deoxyribonuclease 1-like 1  LOC363522  similar to RIKEN cDNA 2310005K03  Symbol and Name updated 1299863 APPROVED
2005-07-29 LOC363522  similar to RIKEN cDNA 2310005K03      Symbol and Name status set to provisional 70820 PROVISIONAL