Dnase1l1 (deoxyribonuclease 1 like 1) - Rat Genome Database

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Gene: Dnase1l1 (deoxyribonuclease 1 like 1) Chinchilla lanigera
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Symbol: Dnase1l1
Name: deoxyribonuclease 1 like 1
RGD ID: 8808737
Description: ASSOCIATED WITH adrenoleukodystrophy (ortholog); autistic disorder (ortholog); autosomal hemophilia A (ortholog); FOUND IN endoplasmic reticulum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: deoxyribonuclease I-like 1; deoxyribonuclease-1-like 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580907,582 - 914,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580907,056 - 913,604 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


1 to 20 of 21 rows
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l1Chinchillaadrenoleukodystrophy  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: AdrenoleukodystrophyClinVarPMID:10480214 more ...
Dnase1l1Chinchillaautistic disorder  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: AutismClinVarPMID:21681106 and PMID:30208311
Dnase1l1Chinchillaautosomal hemophilia A  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: AUTOSOMAL HEMOPHILIA AClinVarPMID:31690835
Dnase1l1ChinchillaBarth syndrome  ISODNASE1L1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10480214 more ...
Dnase1l1Chinchillacardiomyopathy  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: CardiomyopathyClinVarPMID:25741868 and PMID:28492532
Dnase1l1Chinchillacerebral creatine deficiency syndrome 1  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Creatine transporter deficiencyClinVarPMID:10480214 more ...
Dnase1l1Chinchilladilated cardiomyopathy  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Primary dilated cardiomyopathyClinVarPMID:25741868
Dnase1l1ChinchillaDilated Cardiomyopathy with Left Ventricular Noncompaction  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Left ventricular noncompaction cardiomyopathyClinVarPMID:25741868 more ...
Dnase1l1Chinchilladyskeratosis congenita  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Dyskeratosis congenitaClinVarPMID:10480214 more ...
Dnase1l1ChinchillaEmery-Dreifuss muscular dystrophy  ISODNASE1L1 (Homo sapiens)8554872ClinVar more ...ClinVarPMID:10480214 more ...
Dnase1l1ChinchillaEmery-Dreifuss muscular dystrophy  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: X-linked Emery-Dreifuss muscular dystrophyClinVarPMID:10480214 more ...
Dnase1l1Chinchillaendocardial fibroelastosis  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Endocardial fibroelastosisClinVarPMID:25741868
Dnase1l1Chinchillafactor VIII deficiency  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Factor 8 deficiency and congenitalClinVarPMID:31690835
Dnase1l1Chinchillafavism  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Anemia more ...ClinVarPMID:10480214 more ...
Dnase1l1Chinchillaimmunodeficiency 33  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Immunodeficiency 33ClinVarPMID:25741868
Dnase1l1Chinchillaparaplegia  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Spastic paraplegiaClinVarPMID:10480214 more ...
Dnase1l1Chinchillaperiventricular nodular heterotopia  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Heterotopia more ...ClinVarPMID:10480214 more ...
Dnase1l1Chinchillasevere congenital encephalopathy due to MECP2 mutation  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Severe neonatal-onset encephalopathy with microcephalyClinVarPMID:15351775 more ...
Dnase1l1ChinchillaSplenomegaly  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: SplenomegalyClinVarPMID:25741868
Dnase1l1Chinchillasyndromic X-linked intellectual disability Lubs type  ISODNASE1L1 (Homo sapiens)8554872ClinVar Annotator: match by term: Syndromic X-linked intellectual disability Lubs typeClinVarPMID:22679399 more ...
1 to 20 of 21 rows


Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l1Chinchillaendoplasmic reticulum located_inISODNASE1L1 (Homo sapiens)9068941 LIFEdbGO_REF:0000054

Molecular Function

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Dnase1l1Chinchillaprotein binding enablesISOUniProtKB:P110219068941 PMID:30021884 and PMID:33961781IntActPMID:30021884 and PMID:33961781
Dnase1l1Chinchillaprotein binding enablesISOUniProtKB:O76024 more ...9068941 PMID:32814053IntActPMID:32814053


#
Reference Title
Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
PMID:22301074   PMID:30032202  



Dnase1l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580907,582 - 914,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580907,056 - 913,604 (-)NCBIChiLan1.0ChiLan1.0
DNASE1L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X154,401,236 - 154,412,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX154,401,236 - 154,412,112 (-)EnsemblGRCh38hg38GRCh38
GRCh37X153,629,577 - 153,640,438 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,282,773 - 153,293,621 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X153,150,425 - 153,158,422NCBI
CeleraX153,790,635 - 153,801,484 (-)NCBICelera
Cytogenetic MapXq28NCBI
HuRefX142,206,968 - 142,217,816 (-)NCBIHuRef
CHM1_1X153,541,222 - 153,552,074 (-)NCBICHM1_1
T2T-CHM13v2.0X152,637,756 - 152,648,607 (-)NCBIT2T-CHM13v2.0
Dnase1l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,316,823 - 73,325,939 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX73,316,823 - 73,325,943 (-)EnsemblGRCm39 Ensembl
GRCm38X74,273,217 - 74,282,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,273,217 - 74,282,337 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X71,518,556 - 71,527,672 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X70,525,938 - 70,534,454 (-)NCBIMGSCv36mm8
CeleraX65,526,994 - 65,536,124 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.94NCBI
Dnase1l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X157,208,230 - 157,216,812 (-)NCBIGRCr8
mRatBN7.2X152,056,942 - 152,065,518 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX152,056,942 - 152,065,518 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX154,198,071 - 154,206,552 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X157,761,304 - 157,769,785 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X155,433,103 - 155,441,584 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X156,429,521 - 156,438,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX156,429,585 - 156,438,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01152,169,678 - 152,178,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,327,966 - 160,336,447 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X160,404,391 - 160,412,828 (+)NCBI
Celera1135,831,332 - 135,839,813 (+)NCBICelera
Cytogenetic MapXq37NCBI
DNASE1L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X154,376,064 - 154,385,167 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X154,379,690 - 154,388,048 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X143,842,920 - 143,851,795 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X153,712,050 - 153,725,868 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,712,054 - 153,725,868 (-)Ensemblpanpan1.1panPan2
DNASE1L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,101,992 - 122,109,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,101,992 - 122,109,165 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,243,686 - 125,250,933 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX125,243,302 - 125,250,882 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X121,012,760 - 121,020,007 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X123,527,626 - 123,534,873 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X123,289,507 - 123,296,773 (-)NCBIUU_Cfam_GSD_1.0
Dnase1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,413,626 - 119,420,791 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049368091,151,202 - 1,159,029 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049368091,151,312 - 1,159,017 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNASE1L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,931,410 - 124,939,965 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,931,410 - 124,937,569 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DNASE1L1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606566,628,194 - 66,636,944 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnase1l1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624946864,657 - 870,396 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624946858,638 - 869,859 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.





RefSeq Transcripts XM_005414193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AGCD01075629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  GBDK01190187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSCLAT00000005013   ⟹   ENSCLAP00000004921
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955580907,582 - 914,243 (-)Ensembl
Ensembl Acc Id: ENSCLAT00000005014   ⟹   ENSCLAP00000004922
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_004955580907,582 - 914,243 (-)Ensembl
RefSeq Acc Id: XM_005414193   ⟹   XP_005414250
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_004955580907,056 - 913,604 (-)NCBI
Sequence:
Protein RefSeqs XP_005414250 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000004921
  ENSCLAP00000004921.1
  ENSCLAP00000004922.1
RefSeq Acc Id: XP_005414250   ⟸   XM_005414193
- UniProtKB: A0A8C2UYA9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSCLAP00000004921   ⟸   ENSCLAT00000005013
Ensembl Acc Id: ENSCLAP00000004922   ⟸   ENSCLAT00000005014


1 to 19 of 19 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSCLAG00000003494 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005013 ENTREZGENE
  ENSCLAT00000005013.1 UniProtKB/TrEMBL
  ENSCLAT00000005014.1 UniProtKB/TrEMBL
Gene3D-CATH 3.60.10.10 UniProtKB/TrEMBL
InterPro DNase_I UniProtKB/TrEMBL
  DNASE_I_2 UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/TrEMBL
  Endo/exonuclease/phosphatase UniProtKB/TrEMBL
NCBI Gene Dnase1l1 ENTREZGENE
PANTHER DEOXYRIBONUCLEASE UniProtKB/TrEMBL
  DEOXYRIBONUCLEASE-1-LIKE 1 UniProtKB/TrEMBL
Pfam Exo_endo_phos UniProtKB/TrEMBL
PIRSF DNase_I_euk UniProtKB/TrEMBL
PRINTS DNASEI UniProtKB/TrEMBL
PROSITE DNASE_I_2 UniProtKB/TrEMBL
SMART DNaseIc UniProtKB/TrEMBL
Superfamily-SCOP SSF56219 UniProtKB/TrEMBL
UniProt A0A8C2UYA9 ENTREZGENE, UniProtKB/TrEMBL
1 to 19 of 19 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-08-03 Dnase1l1  deoxyribonuclease 1 like 1    deoxyribonuclease I-like 1  Symbol and/or name change 5135510 APPROVED