DNASE1L1 (deoxyribonuclease 1 like 1) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: DNASE1L1 (deoxyribonuclease 1 like 1) Sus scrofa
Analyze
Symbol: DNASE1L1
Name: deoxyribonuclease 1 like 1
RGD ID: 13975237
Description: This gene encodes a member of the deoxyribonuclease family and the protein shows high sequence similarity to lysosomal DNase I. In contrast to the human and mouse orthologs, porcine and bovine mRNAs for this gene use a conserved CUG triplet for translation initiation. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: deoxyribonuclease I-like 1; deoxyribonuclease-1-like 1; DNase I-like 1; DNase X
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,931,408 - 124,939,965 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,931,410 - 124,937,569 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:16107205  


Genomics

Comparative Map Data
DNASE1L1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,931,408 - 124,939,965 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,931,410 - 124,937,569 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DNASE1L1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX154,401,236 - 154,412,112 (-)EnsemblGRCh38hg38GRCh38
GRCh38X154,401,236 - 154,412,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X153,629,577 - 153,640,438 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X153,282,773 - 153,293,621 (-)NCBINCBI36hg18NCBI36
Build 34X153,150,425 - 153,158,422NCBI
CeleraX153,790,635 - 153,801,484 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX142,206,968 - 142,217,816 (-)NCBIHuRef
CHM1_1X153,541,220 - 153,552,075 (-)NCBICHM1_1
Dnase1l1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X73,316,823 - 73,325,939 (-)NCBIGRCm39mm39
GRCm39 EnsemblX73,316,823 - 73,325,943 (-)Ensembl
GRCm38X74,273,217 - 74,282,333 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX74,273,217 - 74,282,337 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X71,518,556 - 71,527,672 (-)NCBIGRCm37mm9NCBIm37
MGSCv36X70,525,938 - 70,534,454 (-)NCBImm8
CeleraX65,526,994 - 65,536,124 (-)NCBICelera
Cytogenetic MapXA7.3NCBI
cM MapX37.94NCBI
Dnase1l1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2X152,056,942 - 152,065,518 (-)NCBI
Rnor_6.0 EnsemblX156,429,585 - 156,438,066 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0X156,429,521 - 156,438,066 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01152,169,678 - 152,178,213 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X160,327,966 - 160,336,447 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X160,404,391 - 160,412,828 (+)NCBI
Celera1135,831,332 - 135,839,813 (+)NCBICelera
Cytogenetic MapXq37NCBI
Dnase1l1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580907,582 - 914,243 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580907,056 - 913,604 (-)NCBIChiLan1.0ChiLan1.0
DNASE1L1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X153,712,050 - 153,725,868 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX153,712,054 - 153,725,868 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0X143,842,920 - 143,851,795 (-)NCBIMhudiblu_PPA_v0panPan3
DNASE1L1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X122,101,992 - 122,109,240 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX122,101,992 - 122,109,165 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.0X125,243,686 - 125,250,933 (-)NCBI
UMICH_Zoey_3.1X121,012,760 - 121,020,007 (-)NCBI
UNSW_CanFamBas_1.0X123,527,626 - 123,534,873 (-)NCBI
UU_Cfam_GSD_1.0X123,289,507 - 123,296,773 (-)NCBI
Dnase1l1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X119,413,626 - 119,420,791 (-)NCBI
SpeTri2.0NW_0049368091,151,312 - 1,159,017 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNASE1L1
(Chlorocebus sabaeus - African green monkey)
No map positions available.
Dnase1l1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624946858,638 - 869,859 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 2 1 2
Low 10 4 3 3 1 14 2 3 1
Below cutoff 9

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000044078   ⟹   ENSSSCP00000034453
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX124,931,408 - 124,939,965 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000050491   ⟹   ENSSSCP00000056134
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 EnsemblX124,931,408 - 124,939,965 (-)Ensembl
RefSeq Acc Id: NM_001038632   ⟹   NP_001033721
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1X124,931,410 - 124,937,569 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001033721 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAZ94275 (Get FASTA)   NCBI Sequence Viewer  
  Q2QDF0 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001033721   ⟸   NM_001038632
- Peptide Label: precursor
- UniProtKB: Q2QDF0 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSSSCP00000056134   ⟸   ENSSSCT00000050491
RefSeq Acc Id: ENSSSCP00000034453   ⟸   ENSSSCT00000044078

Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000037032 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070006674 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000034453 UniProtKB/TrEMBL
  ENSSSCP00000056134 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00070010533 UniProtKB/TrEMBL
  ENSSSCP00070010537 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000044078 UniProtKB/TrEMBL
  ENSSSCT00000050491 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070012799 UniProtKB/TrEMBL
  ENSSSCT00070012803 UniProtKB/TrEMBL
Gene3D-CATH 3.60.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DNase_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DNASE_I_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endo/exonu/phosph_ase_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Endo/exonuclease/phosphatase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report ssc:654408 UniProtKB/Swiss-Prot
NCBI Gene DNASE1L1 ENTREZGENE
Pfam Exo_endo_phos UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PIRSF DNase_I_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS DNASEI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE DNASE_I_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART DNaseIc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56219 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A286ZS28_PIG UniProtKB/TrEMBL
  A0A287BHR4_PIG UniProtKB/TrEMBL
  A0A4X1T3Z4_PIG UniProtKB/TrEMBL
  A0A4X1T572_PIG UniProtKB/TrEMBL
  DNSL1_PIG UniProtKB/Swiss-Prot, ENTREZGENE
VGNC ID VGNC:103936 ENTREZGENE