Depp1 (DEPP autophagy regulator 1) - Rat Genome Database

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Gene: Depp1 (DEPP autophagy regulator 1) Rattus norvegicus
Analyze
Symbol: Depp1
Name: DEPP autophagy regulator 1
RGD ID: 1565700
Description: Predicted to be involved in regulation of autophagy. Predicted to be located in peroxisome. Predicted to be active in mitochondrion. Orthologous to human DEPP1 (DEPP autophagy regulator 1); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: decidual protein induced by progesterone; Depp; DEPP1, autophagy regulator; LOC500300; similar to hypothetical protein MGC6835
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84151,583,105 - 151,585,455 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4151,581,502 - 151,586,233 (+)EnsemblGRCr8
mRatBN7.24149,910,794 - 149,913,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4149,910,779 - 149,914,542 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4156,152,814 - 156,154,892 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04151,936,856 - 151,938,934 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04150,559,748 - 150,561,826 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04148,780,330 - 148,784,566 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4148,782,479 - 148,784,562 (+)Ensemblrn6Rnor6.0
Rnor_5.04214,721,136 - 214,723,301 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44153,000,782 - 153,002,562 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4138,786,484 - 138,788,568 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine  (ISO)
1-naphthyl isothiocyanate  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP,ISO)
acetamide  (EXP)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (ISO)
amitriptyline  (ISO)
Archazolid B  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bromobenzene  (EXP)
butanal  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
capsaicin  (ISO)
chlordecone  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
clomipramine  (ISO)
clozapine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (ISO)
cyanocob(III)alamin  (ISO)
cyclosporin A  (ISO)
cypermethrin  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diazinon  (ISO)
dicrotophos  (ISO)
diiodine  (ISO)
dimethyl sulfoxide  (ISO)
dinophysistoxin 1  (ISO)
diquat  (ISO)
dorsomorphin  (ISO)
doxepin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
erythromycin A  (ISO)
flecainide  (ISO)
fluoxetine  (ISO)
folic acid  (ISO)
formaldehyde  (ISO)
fructose  (ISO)
fulvestrant  (ISO)
glucose  (ISO)
glycidol  (ISO)
glycine betaine  (ISO)
haloperidol  (ISO)
herbicide  (ISO)
hydrogen cyanide  (ISO)
imipramine  (ISO)
indometacin  (ISO)
inulin  (ISO)
isoniazide  (ISO)
ketoconazole  (ISO)
L-methionine  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
medroxyprogesterone acetate  (ISO)
methamphetamine  (ISO)
mifepristone  (ISO)
naled  (ISO)
nickel sulfate  (ISO)
nitrofen  (EXP)
ofloxacin  (ISO)
okadaic acid  (ISO)
p-anisidine  (ISO)
paracetamol  (ISO)
pentamidine  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
perhexiline  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pioglitazone  (ISO)
potassium cyanide  (ISO)
progesterone  (ISO)
quercetin  (ISO)
quinidine  (ISO)
quinolin-8-ol  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sertraline  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sotalol  (ISO)
sotorasib  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
thioacetamide  (EXP)
thioridazine  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trametinib  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zimeldine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
regulation of autophagy  (IBA,IEA,ISO)

Cellular Component
cytoplasm  (IEA,ISO)
mitochondrion  (IBA,IEA,ISO)
peroxisome  (IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:15977181   PMID:18614015   PMID:25261981   PMID:28545464  


Genomics

Comparative Map Data
Depp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84151,583,105 - 151,585,455 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl4151,581,502 - 151,586,233 (+)EnsemblGRCr8
mRatBN7.24149,910,794 - 149,913,013 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4149,910,779 - 149,914,542 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx4156,152,814 - 156,154,892 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04151,936,856 - 151,938,934 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04150,559,748 - 150,561,826 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.04148,780,330 - 148,784,566 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4148,782,479 - 148,784,562 (+)Ensemblrn6Rnor6.0
Rnor_5.04214,721,136 - 214,723,301 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.44153,000,782 - 153,002,562 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera4138,786,484 - 138,788,568 (+)NCBICelera
Cytogenetic Map4q42NCBI
DEPP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381044,976,128 - 44,978,809 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1044,970,981 - 44,978,809 (-)Ensemblhg38GRCh38
GRCh371045,471,576 - 45,474,257 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361044,791,715 - 44,794,336 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341044,791,716 - 44,794,263NCBI
Celera1041,474,883 - 41,477,504 (-)NCBICelera
Cytogenetic Map10q11.21NCBI
HuRef1041,996,250 - 41,998,871 (-)NCBIHuRef
CHM1_11045,510,686 - 45,513,307 (-)NCBICHM1_1
T2T-CHM13v2.01045,857,092 - 45,859,773 (-)NCBIT2T-CHM13v2.0
Depp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396116,627,645 - 116,629,808 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6116,627,570 - 116,629,755 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm386116,650,684 - 116,652,847 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6116,650,609 - 116,652,794 (+)Ensemblmm10GRCm38
MGSCv376116,600,702 - 116,602,865 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv366116,616,318 - 116,618,413 (+)NCBIMGSCv36mm8
Celera6118,491,933 - 118,494,097 (+)NCBICelera
Cytogenetic Map6E3NCBI
cM Map653.83NCBI
Depp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555462,291,829 - 2,293,375 (-)Ensembl
ChiLan1.0NW_0049555462,291,829 - 2,293,375 (-)NCBIChiLan1.0ChiLan1.0
DEPP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2857,712,084 - 57,713,637 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11057,717,413 - 57,718,929 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01041,970,914 - 41,973,518 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11045,150,510 - 45,153,157 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1045,151,636 - 45,152,280 (-)EnsemblpanPan2panpan1.1
DEPP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1282,463,770 - 2,465,240 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl282,464,584 - 2,465,210 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha282,699,175 - 2,700,647 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0282,642,640 - 2,644,112 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl282,643,452 - 2,644,078 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1282,441,206 - 2,442,678 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0282,478,478 - 2,479,950 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0282,609,647 - 2,611,119 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Depp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721382,041,955 - 82,043,912 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366174,740,103 - 4,740,741 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366174,740,073 - 4,743,610 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEPP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1491,114,441 - 91,122,191 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11491,118,332 - 91,120,242 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21499,353,238 - 99,354,838 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DEPP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1940,602,193 - 40,603,791 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl940,602,223 - 40,602,861 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605645,800,538 - 45,802,078 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Depp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004628729538 - 1,142 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Depp1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1629,955,032 - 29,957,125 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Depp1
10 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:65
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000018133
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4146370897184426481Rat
2302049Pia32Pristane induced arthritis QTL 325.10.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)4107346299152346299Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4134095016179095016Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4149763204169799698Rat
61446Coreg2Compensatory renal growth QTL 23.5kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)4150095743159267220Rat
1300116Hrtrt5Heart rate QTL 53.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)4117737142152833657Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4146370897184426481Rat
1358364Sradr4Stress Responsive Adrenal Weight QTL 44.92adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)4131384565176384565Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)427730518170099664Rat
6478763Anxrr46Anxiety related response QTL 460.07428locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
6478760Anxrr45Anxiety related response QTL 450.06717locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4112427331157427331Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4123870974168870974Rat
1331802Srn5Serum renin concentration QTL 53.045renin activity (VT:0005581)plasma renin activity level (CMO:0000116)4117559384162559384Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4140059299181024663Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)460916264184426481Rat
7207480Bss105Bone structure and strength QTL 1058.1femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)4111383604156383604Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)494638356168870820Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4106848959168870974Rat
731165Uae21Urinary albumin excretion QTL 212.40.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)4108206096153206096Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4127263297172263297Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4126334185171334185Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4147299608184426481Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
1549832Bss3Bone structure and strength QTL 311femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)4111383604156383604Rat
70177Xhs1X-ray hypersensitivity QTL 125.1intestine integrity trait (VT:0010554)post-insult time to onset of moribundity (CMO:0001896)482944895154403548Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4124700988169700988Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264174095838Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)4100752691179366077Rat
1581566Eae21Experimental allergic encephalomyelitis QTL 216.2body mass (VT:0001259)maximum body weight loss to initial body weight ratio (CMO:0001400)4137447185182447185Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)445429709157555683Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4137430611182430611Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)460916264184426481Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)486709649168870974Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4134199006168870974Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4148121375176967367Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4123870974168870974Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4140059299184426481Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)465495851159259805Rat
12798519Anxrr54Anxiety related response QTL 542.540.05locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4116184844161184844Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)412212457182430611Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4146370897184426481Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4148834094168870974Rat

Markers in Region
RH141008  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24149,912,572 - 149,912,792 (+)MAPPERmRatBN7.2
Rnor_6.04148,784,126 - 148,784,345NCBIRnor6.0
Rnor_5.04214,722,861 - 214,723,080UniSTSRnor5.0
RGSC_v3.44153,002,125 - 153,002,344UniSTSRGSC3.4
Celera4138,788,131 - 138,788,350UniSTS
RH 3.4 Map4966.6UniSTS
Cytogenetic Map4q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 161 91 90 59 53 59 6 317 153 11 140 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000018133   ⟹   ENSRNOP00000018133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4151,583,359 - 151,586,233 (+)Ensembl
mRatBN7.2 Ensembl4149,910,779 - 149,914,542 (+)Ensembl
Rnor_6.0 Ensembl4148,782,479 - 148,784,562 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000129903   ⟹   ENSRNOP00000112774
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl4151,581,502 - 151,585,441 (+)Ensembl
RefSeq Acc Id: NM_001024334   ⟹   NP_001019505
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84151,583,371 - 151,585,455 (+)NCBI
mRatBN7.24149,910,926 - 149,913,010 (+)NCBI
Rnor_6.04148,782,479 - 148,784,563 (+)NCBI
Rnor_5.04214,721,136 - 214,723,301 (+)NCBI
RGSC_v3.44153,000,782 - 153,002,562 (+)RGD
Celera4138,786,484 - 138,788,568 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237196   ⟹   XP_006237258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84151,583,109 - 151,585,455 (+)NCBI
mRatBN7.24149,910,796 - 149,913,013 (+)NCBI
Rnor_6.04148,780,331 - 148,784,566 (+)NCBI
Rnor_5.04214,721,136 - 214,723,301 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006237197   ⟹   XP_006237259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84151,583,105 - 151,585,455 (+)NCBI
mRatBN7.24149,910,794 - 149,913,013 (+)NCBI
Rnor_6.04148,780,330 - 148,784,566 (+)NCBI
Rnor_5.04214,721,136 - 214,723,301 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001019505 (Get FASTA)   NCBI Sequence Viewer  
  XP_006237258 (Get FASTA)   NCBI Sequence Viewer  
  XP_006237259 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH87112 (Get FASTA)   NCBI Sequence Viewer  
  AAX31278 (Get FASTA)   NCBI Sequence Viewer  
  EDM02113 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000018133
GenBank Protein Q5BMD4 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001019505   ⟸   NM_001024334
- UniProtKB: Q5PQM5 (UniProtKB/Swiss-Prot),   Q5BMD4 (UniProtKB/Swiss-Prot),   A0A0G2JSM9 (UniProtKB/TrEMBL),   A6IL27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237259   ⟸   XM_006237197
- Peptide Label: isoform X1
- UniProtKB: Q5PQM5 (UniProtKB/Swiss-Prot),   Q5BMD4 (UniProtKB/Swiss-Prot),   A0A0G2JSM9 (UniProtKB/TrEMBL),   A6IL27 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237258   ⟸   XM_006237196
- Peptide Label: isoform X1
- UniProtKB: Q5PQM5 (UniProtKB/Swiss-Prot),   Q5BMD4 (UniProtKB/Swiss-Prot),   A0A0G2JSM9 (UniProtKB/TrEMBL),   A6IL27 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018133   ⟸   ENSRNOT00000018133
Ensembl Acc Id: ENSRNOP00000112774   ⟸   ENSRNOT00000129903

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5BMD4-F1-model_v2 AlphaFold Q5BMD4 1-205 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693337
Promoter ID:EPDNEW_R3861
Type:single initiation site
Name:Depp1_1
Description:DEPP1, autophagy regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04148,782,466 - 148,782,526EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1565700 AgrOrtholog
BioCyc Gene G2FUF-43279 BioCyc
Ensembl Genes ENSRNOG00000023465 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000018133 ENTREZGENE
IMAGE_CLONE IMAGE:7193534 IMAGE-MGC_LOAD
InterPro DEPP UniProtKB/Swiss-Prot
KEGG Report rno:500300 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94732 IMAGE-MGC_LOAD
NCBI Gene 500300 ENTREZGENE
PANTHER PROTEIN DEPP1 UniProtKB/Swiss-Prot
  PTHR15426 UniProtKB/Swiss-Prot
Pfam DEPP UniProtKB/Swiss-Prot
PhenoGen Depp1 PhenoGen
RatGTEx ENSRNOG00000023465 RatGTEx
UniProt A0A0G2JSM9 ENTREZGENE, UniProtKB/TrEMBL
  A6IL27 ENTREZGENE, UniProtKB/TrEMBL
  DEPP_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5PQM5 ENTREZGENE
UniProt Secondary Q5PQM5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-09-30 Depp1  DEPP autophagy regulator 1  Depp1  DEPP1, autophagy regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-11-17 Depp1  DEPP1, autophagy regulator  LOC500300  similar to hypothetical protein MGC6835  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC500300  similar to hypothetical protein MGC6835      Symbol and Name status set to provisional 70820 PROVISIONAL