Igsf10 (immunoglobulin superfamily, member 10) - Rat Genome Database

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Gene: Igsf10 (immunoglobulin superfamily, member 10) Rattus norvegicus
Analyze
Symbol: Igsf10
Name: immunoglobulin superfamily, member 10
RGD ID: 735030
Description: Involved in tissue regeneration. Acts upstream of or within ossification. Predicted to be active in extracellular region. Orthologous to human IGSF10 (immunoglobulin superfamily member 10); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: bone specific CMF608; calvaria mechanical force protein 608; CMF608; immunoglobulin superfamily member 10; LOC310448
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82145,725,868 - 145,754,850 (-)NCBIGRCr8
mRatBN7.22143,575,710 - 143,605,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2143,576,070 - 143,604,773 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2150,215,446 - 150,244,161 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02148,327,870 - 148,356,620 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02142,960,281 - 142,989,031 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02149,535,199 - 149,564,180 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2149,533,151 - 149,564,113 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02168,967,564 - 168,996,524 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42148,704,646 - 148,734,103 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12148,654,608 - 148,684,073 (-)NCBI
Celera2138,000,516 - 138,029,209 (-)NCBICelera
Cytogenetic Map2q26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Igsf10Ratgenetic disease  ISORGD:13526528554872ClinVar Annotator: match by term: Inborn genetic diseasesClinVar 
Igsf10Ratglycogen storage disease XV  ISORGD:13526528554872ClinVar Annotator: match by term: Glycogen storage disease XVClinVarPMID:20357282|PMID:25272951|PMID:28492532
Igsf10RatMartsolf syndrome 1  ISORGD:13526528554872ClinVar Annotator: match by term: Martsolf syndrome 1ClinVarPMID:25741868
Igsf10RatPrimary Ovarian Failure  ISORGD:13526528554872ClinVar Annotator: match by term: Primary ovarian failureClinVarPMID:28492532|PMID:31042289
Igsf10Ratprimary ovarian insufficiency  ISORGD:13526528554872ClinVar Annotator: match by term: Premature ovarian failureClinVarPMID:25741868|PMID:28492532|PMID:31042289

1 to 20 of 73 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Igsf10Rat1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene multiple interactionsISORGD:16220386480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Igsf10Rat17alpha-ethynylestradiol decreases expressionEXP 6480464Ethinyl Estradiol results in decreased expression of IGSF10 mRNACTDPMID:17557909
Igsf10Rat17beta-estradiol increases expressionISORGD:16220386480464Estradiol results in increased expression of IGSF10 mRNACTDPMID:19484750
Igsf10Rat17beta-estradiol increases expressionEXP 6480464Estradiol results in increased expression of IGSF10 mRNACTDPMID:32145629
Igsf10Rat17beta-estradiol multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of IGSF10 mRNACTDPMID:32741896
Igsf10Rat17beta-estradiol 3-benzoate multiple interactionsEXP 6480464[estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of IGSF10 mRNACTDPMID:32741896
Igsf10Rat2,2',4,4',5,5'-hexachlorobiphenyl multiple interactionsISORGD:16220386480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Igsf10Rat2,2',5,5'-tetrachlorobiphenyl multiple interactionsISORGD:16220386480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Igsf10Rat2,2',5,5'-tetrachlorobiphenyl increases expressionISORGD:135265264804642,5,2',5'-tetrachlorobiphenyl analog results in increased expression of IGSF10 mRNACTDPMID:36804509
Igsf10Rat2,3,7,8-tetrachlorodibenzodioxine decreases expressionEXP 6480464Tetrachlorodibenzodioxin results in decreased expression of IGSF10 mRNACTDPMID:33387578
Igsf10Rat2,4,4'-trichlorobiphenyl multiple interactionsISORGD:16220386480464[2,4,4'-trichlorobiphenyl co-treated with 2,5,2',5'-tetrachlorobiphenyl co-treated with 2,4,5,2',5'-pentachlorobiphenyl co-treated with 2,2',3',4,4',5-hexachlorobiphenyl co-treated with 2,4,5,2',4',5'-hexachlorobiphenyl co-treated with more ...CTDPMID:25510870
Igsf10Rat3-isobutyl-1-methyl-7H-xanthine multiple interactionsISORGD:13526526480464[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ...CTDPMID:28628672
Igsf10Rat4,4'-sulfonyldiphenol increases expressionISORGD:16220386480464bisphenol S results in increased expression of IGSF10 mRNACTDPMID:30951980
Igsf10Rat6-propyl-2-thiouracil increases expressionEXP 6480464Propylthiouracil results in increased expression of IGSF10 mRNACTDPMID:24780913
Igsf10Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of IGSF10 mRNACTDPMID:30047161
Igsf10Rat7,12-dimethyltetraphene decreases expressionEXP 64804649,10-Dimethyl-1,2-benzanthracene results in decreased expression of IGSF10 mRNACTDPMID:19480007
Igsf10Ratbenzo[a]pyrene decreases expressionISORGD:13526526480464Benzo(a)pyrene results in decreased expression of IGSF10 mRNACTDPMID:20106945|PMID:32234424
Igsf10Ratbenzo[a]pyrene increases methylationISORGD:13526526480464Benzo(a)pyrene results in increased methylation of IGSF10 promoterCTDPMID:27901495
Igsf10Ratbenzo[a]pyrene decreases expressionISORGD:16220386480464Benzo(a)pyrene results in decreased expression of IGSF10 mRNACTDPMID:21569818
Igsf10Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of IGSF10 mRNACTDPMID:25181051

1 to 20 of 73 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Igsf10Ratcell differentiation involved_inIEAUniProtKB-KW:KW-02211600115GO_REF:0000043UniProtGO_REF:0000043
Igsf10Ratnervous system development involved_inIEAARBA:ARBA000274281600115GO_REF:0000117UniProtGO_REF:0000117
Igsf10Ratossification acts_upstream_of_or_withinIDA 1302504PMID:14962803MGI 
Igsf10Ratossification involved_inIEAUniProtKB-KW:KW-08921600115GO_REF:0000043UniProtGO_REF:0000043
Igsf10Ratregulation of neuron migration involved_inISORGD:16220381624291 PMID:27137492RGDPMID:27137492
Igsf10Ratregulation of neuron migration involved_inISSUniProtKB:Q3V1M11600115GO_REF:0000024UniProtGO_REF:0000024
Igsf10Rattissue regeneration  IDA 1302504 RGD 

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Igsf10Ratextracellular region located_inISORGD:13526521624291 PMID:27137492RGDPMID:27137492
Igsf10Ratextracellular region located_inIEAUniProtKB-SubCell:SL-02431600115GO_REF:0000044UniProtGO_REF:0000044
Igsf10Ratextracellular region is_active_inIBAPANTHER:PTN000051668|UniProtKB:Q6WRI01600115GO_REF:0000033GO_CentralGO_REF:0000033
Igsf10Ratextracellular region located_inIEAUniProtKB-KW:KW-09641600115GO_REF:0000043UniProtGO_REF:0000043
Igsf10Ratextracellular region located_inISSUniProtKB:Q6WRI01600115GO_REF:0000024UniProtGO_REF:0000024


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. CMF608-a novel mechanical strain-induced bone-specific protein expressed in early osteochondroprogenitor cells. Segev O, etal., Bone 2004 Feb;34(2):246-60.
PMID:27137492  



Igsf10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82145,725,868 - 145,754,850 (-)NCBIGRCr8
mRatBN7.22143,575,710 - 143,605,044 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2143,576,070 - 143,604,773 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2150,215,446 - 150,244,161 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02148,327,870 - 148,356,620 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02142,960,281 - 142,989,031 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02149,535,199 - 149,564,180 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2149,533,151 - 149,564,113 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02168,967,564 - 168,996,524 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42148,704,646 - 148,734,103 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12148,654,608 - 148,684,073 (-)NCBI
Celera2138,000,516 - 138,029,209 (-)NCBICelera
Cytogenetic Map2q26NCBI
IGSF10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383151,432,432 - 151,619,925 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3151,425,384 - 151,461,061 (-)EnsemblGRCh38hg38GRCh38
GRCh373151,153,991 - 151,257,104 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363152,637,167 - 152,659,187 (-)NCBINCBI36Build 36hg18NCBI36
Build 343152,637,174 - 152,659,195NCBI
Celera3149,572,109 - 149,594,842 (-)NCBICelera
Cytogenetic Map3q25.1NCBI
HuRef3148,533,138 - 148,555,872 (-)NCBIHuRef
CHM1_13151,116,911 - 151,139,641 (-)NCBICHM1_1
T2T-CHM13v2.03154,193,223 - 154,376,990 (-)NCBIT2T-CHM13v2.0
Igsf10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39359,224,156 - 59,256,836 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl359,224,156 - 59,251,815 (-)EnsemblGRCm39 Ensembl
GRCm38359,316,735 - 59,344,438 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl359,316,735 - 59,344,394 (-)EnsemblGRCm38mm10GRCm38
MGSCv37359,120,657 - 59,148,178 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36359,404,664 - 59,432,185 (-)NCBIMGSCv36mm8
Celera359,004,000 - 59,031,501 (-)NCBICelera
Cytogenetic Map3DNCBI
cM Map329.03NCBI
Igsf10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554482,528,703 - 2,557,656 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554482,532,973 - 2,557,650 (-)NCBIChiLan1.0ChiLan1.0
IGSF10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22149,334,202 - 149,362,921 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13149,339,410 - 149,361,474 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03148,461,331 - 148,488,696 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13156,033,528 - 156,056,003 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3156,030,099 - 156,056,003 (-)Ensemblpanpan1.1panPan2
IGSF10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12346,002,163 - 46,058,656 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2346,002,308 - 46,059,936 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2345,866,591 - 45,923,482 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02346,628,844 - 46,685,867 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2346,629,318 - 46,687,214 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12346,217,698 - 46,274,621 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02346,269,685 - 46,326,605 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02346,546,832 - 46,603,735 (-)NCBIUU_Cfam_GSD_1.0
Igsf10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560290,079,550 - 90,109,254 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367581,660,313 - 1,686,404 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367581,660,254 - 1,686,404 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IGSF10
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1391,625,431 - 91,679,079 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11391,625,421 - 91,679,494 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21399,845,339 - 99,881,443 (-)NCBISscrofa10.2Sscrofa10.2susScr3
IGSF10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11539,200,244 - 39,266,759 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1539,240,849 - 39,265,142 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604112,055,884 - 12,081,599 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Igsf10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473028,862,656 - 28,890,263 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473028,862,624 - 28,891,855 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

.
Variants in Igsf10
141 total Variants

Predicted Target Of
Summary Value
Count of predictions:72
Count of miRNA genes:66
Interacting mature miRNAs:70
Transcripts:ENSRNOT00000018628
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 68 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2102803808147803808Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
6907363Bp357Blood pressure QTL 3574.10.002arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2129540907174540907Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1358360Sradr2Stress Responsive Adrenal Weight QTL 210.24adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)2129164097152195315Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat

1 to 10 of 68 rows
RH134080  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr82145,744,573 - 145,744,765 (+)Marker Load Pipeline
mRatBN7.22143,594,767 - 143,594,959 (+)MAPPERmRatBN7.2
Rnor_6.02149,553,891 - 149,554,082NCBIRnor6.0
Rnor_5.02168,986,267 - 168,986,458UniSTSRnor5.0
RGSC_v3.42148,723,338 - 148,723,529UniSTSRGSC3.4
Celera2138,019,204 - 138,019,395UniSTS
RH 3.4 Map2880.9UniSTS
Cytogenetic Map2q31UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31



Ensembl Acc Id: ENSRNOT00000018628   ⟹   ENSRNOP00000018629
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2143,576,070 - 143,604,773 (-)Ensembl
Rnor_6.0 Ensembl2149,535,484 - 149,564,113 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000086186   ⟹   ENSRNOP00000069220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2149,533,151 - 149,563,905 (-)Ensembl
RefSeq Acc Id: NM_198768   ⟹   NP_942063
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82145,725,878 - 145,754,579 (-)NCBI
mRatBN7.22143,576,068 - 143,604,773 (-)NCBI
Rnor_6.02149,535,199 - 149,563,896 (-)NCBI
Rnor_5.02168,967,564 - 168,996,524 (-)NCBI
RGSC_v3.42148,704,646 - 148,734,103 (-)RGD
Celera2138,000,516 - 138,029,209 (-)RGD
Sequence:
RefSeq Acc Id: XM_017590862   ⟹   XP_017446351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82145,725,868 - 145,754,850 (-)NCBI
mRatBN7.22143,575,710 - 143,605,043 (-)NCBI
Rnor_6.02149,535,212 - 149,564,180 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039102264   ⟹   XP_038958192
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82145,725,868 - 145,754,636 (-)NCBI
mRatBN7.22143,575,710 - 143,604,833 (-)NCBI
RefSeq Acc Id: XM_039102265   ⟹   XP_038958193
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82145,725,868 - 145,754,850 (-)NCBI
mRatBN7.22143,575,710 - 143,605,044 (-)NCBI
RefSeq Acc Id: XM_039102266   ⟹   XP_038958194
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82145,725,868 - 145,754,850 (-)NCBI
mRatBN7.22143,575,710 - 143,605,044 (-)NCBI
RefSeq Acc Id: XM_039102267   ⟹   XP_038958195
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82145,725,868 - 145,754,850 (-)NCBI
mRatBN7.22143,575,710 - 143,605,044 (-)NCBI
RefSeq Acc Id: XM_039102268   ⟹   XP_038958196
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82145,725,868 - 145,745,878 (-)NCBI
mRatBN7.22143,575,710 - 143,596,697 (-)NCBI
RefSeq Acc Id: NP_942063   ⟸   NM_198768
- Peptide Label: precursor
- UniProtKB: Q6WRH9 (UniProtKB/Swiss-Prot),   G3V7S1 (UniProtKB/TrEMBL),   A6JVK7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446351   ⟸   XM_017590862
- Peptide Label: isoform X2
- UniProtKB: Q6WRH9 (UniProtKB/Swiss-Prot),   G3V7S1 (UniProtKB/TrEMBL),   A6JVK7 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000018629   ⟸   ENSRNOT00000018628
Ensembl Acc Id: ENSRNOP00000069220   ⟸   ENSRNOT00000086186
RefSeq Acc Id: XP_038958195   ⟸   XM_039102267
- Peptide Label: isoform X1
- UniProtKB: Q6WRH9 (UniProtKB/Swiss-Prot)
Ig-like   Ig-like C2-type   LRRCT   LRRNT

Name Modeler Protein Id AA Range Protein Structure
AF-Q6WRH9-F1-model_v2 AlphaFold Q6WRH9 1-2597 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691350
Promoter ID:EPDNEW_R1874
Type:initiation region
Name:Igsf10_1
Description:immunoglobulin superfamily, member 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02149,564,087 - 149,564,147EPDNEW


1 to 40 of 41 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-52984 BioCyc
Ensembl Genes ENSRNOG00000013917 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000018628 ENTREZGENE
  ENSRNOT00000136047 ENTREZGENE
  ENSRNOT00000152418 ENTREZGENE
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot
InterPro Cys-rich_flank_reg_C UniProtKB/Swiss-Prot
  Ig-like_dom UniProtKB/Swiss-Prot
  Ig-like_dom_sf UniProtKB/Swiss-Prot
  Ig-like_fold UniProtKB/Swiss-Prot
  Ig_I-set UniProtKB/Swiss-Prot
  Ig_sub UniProtKB/Swiss-Prot
  Ig_sub2 UniProtKB/Swiss-Prot
  Ig_V-set UniProtKB/Swiss-Prot
  Leu-rich_rpt UniProtKB/Swiss-Prot
  Leu-rich_rpt_typical-subtyp UniProtKB/Swiss-Prot
  LRFN UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
KEGG Report rno:310448 UniProtKB/Swiss-Prot
NCBI Gene 310448 ENTREZGENE
PANTHER KEKKON 5, ISOFORM A UniProtKB/Swiss-Prot
  SYNAPTIC ADHESION-LIKE MOLECULE SALM UniProtKB/Swiss-Prot
Pfam I-set UniProtKB/Swiss-Prot
  Ig_3 UniProtKB/Swiss-Prot
  LRR_8 UniProtKB/Swiss-Prot
PhenoGen Igsf10 PhenoGen
PROSITE IG_LIKE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000013917 RatGTEx
SMART IGc2 UniProtKB/Swiss-Prot
  IGv UniProtKB/Swiss-Prot
  LRR_TYP UniProtKB/Swiss-Prot
  LRRCT UniProtKB/Swiss-Prot
  LRRNT UniProtKB/Swiss-Prot
  SM00409 UniProtKB/Swiss-Prot
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot
  SSF48726 UniProtKB/Swiss-Prot
UniProt A6JVK7 ENTREZGENE, UniProtKB/TrEMBL
  G3V7S1 ENTREZGENE, UniProtKB/TrEMBL
1 to 40 of 41 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-11-17 Igsf10  immunoglobulin superfamily, member 10      Name updated 1299863 APPROVED
2004-09-10 Igsf10  bone specific CMF608  LOC310448    Symbol and Name updated 1299863 APPROVED

Note Type Note Reference
gene_domains contains an N-terminal signal peptide, six leucine-rich repeats, and 12 immunoglobulin-like repeats, 10 of which are clustered in the C-terminus 1302504
gene_expression highest expression in mesenchymal osteochondroprogenitors with fibroblast-like morphology found in the perichondral fibrous ring of La Croix, periosteum, endosteum of normal bone as well as in the activated periosteum and early fibrous callus generated postfracture 1302504
gene_regulation is up-regulated in response to mechanical force and appears to be down-regulated prior to terminal differentiation 1302504