Adar (adenosine deaminase, RNA-specific) - Rat Genome Database

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Gene: Adar (adenosine deaminase, RNA-specific) Rattus norvegicus
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Symbol: Adar
Name: adenosine deaminase, RNA-specific
RGD ID: 71099
Description: Predicted to enable double-stranded RNA adenosine deaminase activity; double-stranded RNA binding activity; and tRNA-specific adenosine deaminase activity. Predicted to be involved in several processes, including RNA metabolic process; nucleocytoplasmic transport; and positive regulation of viral genome replication. Predicted to act upstream of or within several processes, including hematopoietic stem cell homeostasis; hemopoiesis; and regulatory ncRNA-mediated gene silencing. Located in nuclear speck. Human ortholog(s) of this gene implicated in Aicardi-Goutieres syndrome; Human papillomavirus infectious disease; dyschromatosis symmetrica hereditaria; and liver cirrhosis. Orthologous to human ADAR (adenosine deaminase RNA specific); PARTICIPATES IN microRNA pathway; influenza A pathway; measles pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: adenosine deaminase RNA-specific; double-stranded RNA-specific adenosine deaminase; DRADA
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,436,076 - 177,475,969 (+)NCBIGRCr8
mRatBN7.22175,138,391 - 175,178,280 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,138,403 - 175,178,282 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2182,303,808 - 182,324,734 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,326,190 - 180,347,116 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,927,089 - 174,948,007 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,045,551 - 189,085,448 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,062,443 - 189,083,236 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,468,426 - 208,506,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,935,246 - 181,956,039 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12181,885,351 - 181,906,145 (+)NCBI
Celera2169,097,840 - 169,118,615 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-chloropropane-1,2-diol  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
clofibrate  (ISO)
clotrimazole  (EXP)
crocidolite asbestos  (ISO)
decabromodiphenyl ether  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
FR900359  (ISO)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
inulin  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
maneb  (ISO)
methimazole  (EXP)
methotrexate  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
poly(I:C)  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP)
tetrachloromethane  (ISO)
triptonide  (ISO)
tungsten  (ISO)
uranium atom  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
nuclear speck  (IDA)
nucleolus  (IBA,IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (ISO)
supraspliceosomal complex  (IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ADAR1 overexpression is associated with cervical cancer progression and angiogenesis. Chen Y, etal., Diagn Pathol. 2017 Jan 21;12(1):12. doi: 10.1186/s13000-017-0600-0.
2. Dynamic association of RNA-editing enzymes with the nucleolus. Desterro JM, etal., J Cell Sci. 2003 May 1;116(Pt 9):1805-18.
3. Janus effects of ADAR1 on CVB3-induced viral myocarditis at different infection stages. Dong N, etal., Int J Cardiol. 2016 Nov 15;223:898-905. doi: 10.1016/j.ijcard.2016.08.315. Epub 2016 Aug 22.
4. Integrative role of vitamin D related and Interleukin-28B genes polymorphism in predicting treatment outcomes of Chronic Hepatitis C. El-Derany MO, etal., BMC Gastroenterol. 2016 Feb 24;16:19. doi: 10.1186/s12876-016-0440-5.
5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. A-to-I editing of microRNAs: regulating the regulators? Gommans WM Semin Cell Dev Biol. 2012 May;23(3):251-7. doi: 10.1016/j.semcdb.2011.09.018. Epub 2011 Oct 5.
7. Gene-gene and gene-environment interactions in interferon therapy for chronic hepatitis C. Lin E, etal., Pharmacogenomics. 2007 Oct;8(10):1327-35. doi: 10.2217/14622416.8.10.1327.
8. ADAR1 polymorphisms are related to severity of liver fibrosis in HIV/HCV-coinfected patients. Medrano LM, etal., Sci Rep. 2017 Oct 10;7(1):12918. doi: 10.1038/s41598-017-12885-4.
9. Gene Data Set MGD Curation, June 12, 2002
10. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
11. Mutations of the RNA-specific adenosine deaminase gene (DSRAD) are involved in dyschromatosis symmetrica hereditaria. Miyamura Y, etal., Am J Hum Genet. 2003 Sep;73(3):693-9. Epub 2003 Aug 11.
12. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
13. Cloning of cDNAs encoding mammalian double-stranded RNA-specific adenosine deaminase. O'Connell MA, etal., Mol Cell Biol 1995 Mar;15(3):1389-97.
14. Enhanced AZIN1 RNA editing and overexpression of its regulatory enzyme ADAR1 are important prognostic biomarkers in gastric cancer. Okugawa Y, etal., J Transl Med. 2018 Dec 18;16(1):366. doi: 10.1186/s12967-018-1740-z.
15. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. ADAR1 affects HCV infection by modulating innate immune response. Pujantell M, etal., Antiviral Res. 2018 Aug;156:116-127. doi: 10.1016/j.antiviral.2018.05.012. Epub 2018 Jun 12.
18. ADAR1 function affects HPV replication and is associated to recurrent human papillomavirus-induced dysplasia in HIV coinfected individuals. Pujantell M, etal., Sci Rep. 2019 Dec 27;9(1):19848. doi: 10.1038/s41598-019-56422-x.
19. GOA pipeline RGD automated data pipeline
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. Comprehensive gene review and curation RGD comprehensive gene curation
23. Mutations in ADAR1 cause Aicardi-Goutieres syndrome associated with a type I interferon signature. Rice GI, etal., Nat Genet. 2012 Nov;44(11):1243-8. doi: 10.1038/ng.2414. Epub 2012 Sep 23.
24. Editing of AMPA and serotonin 2C receptors in individual central neurons, controlling wakefulness. Sergeeva OA, etal., Cell Mol Neurobiol. 2007 Aug;27(5):669-80.
25. Tissue selectivity of interferon-stimulated gene expression in mice infected with Dam(+) versus Dam(-) Salmonella enterica serovar Typhimurium strains. Shtrichman R, etal., Infect Immun. 2002 Oct;70(10):5579-88. doi: 10.1128/iai.70.10.5579-5588.2002.
26. Mutation analysis of the ADAR1 gene in dyschromatosis symmetrica hereditaria and genetic differentiation from both dyschromatosis universalis hereditaria and acropigmentatio reticularis. Suzuki N, etal., J Invest Dermatol. 2005 Jun;124(6):1186-92.
27. Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene. Wang Q, etal., J Biol Chem. 2004 Feb 6;279(6):4952-61. Epub 2003 Nov 12.
28. Requirement of the RNA editing deaminase ADAR1 gene for embryonic erythropoiesis. Wang Q, etal., Science 2000 Dec 1;290(5497):1765-8.
29. Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial. Welzel TM, etal., Hepatology. 2009 Jun;49(6):1847-58. doi: 10.1002/hep.22877.
30. A functional polymorphism in ADAR1 gene affects HBsAg seroclearance both spontaneously and interferon induced. Wu X, etal., Liver Int. 2014 Nov;34(10):1560-5. doi: 10.1111/liv.12444. Epub 2014 Jan 16.
31. Adenosine deaminase that acts on RNA 1 p150 in alveolar macrophage is involved in LPS-induced lung injury. Wu Y, etal., Shock. 2009 Apr;31(4):410-15. doi: 10.1097/SHK.0b013e31817c1068.
32. ADAR1p150 Forms a Complex with Dicer to Promote miRNA-222 Activity and Regulate PTEN Expression in CVB3-Induced Viral Myocarditis. Zhang X, etal., Int J Mol Sci. 2019 Jan 18;20(2). pii: ijms20020407. doi: 10.3390/ijms20020407.
Additional References at PubMed
PMID:9020165   PMID:12954622   PMID:14615479   PMID:15556947   PMID:15858013   PMID:16475990   PMID:17369310   PMID:18362360   PMID:19060901   PMID:19124606   PMID:19651874   PMID:19805087  
PMID:19946888   PMID:21173229   PMID:21289159   PMID:22658674   PMID:22681889   PMID:23123729   PMID:23209284   PMID:23622242   PMID:24882218   PMID:28355180   PMID:31505169  


Genomics

Comparative Map Data
Adar
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82177,436,076 - 177,475,969 (+)NCBIGRCr8
mRatBN7.22175,138,391 - 175,178,280 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2175,138,403 - 175,178,282 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2182,303,808 - 182,324,734 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02180,326,190 - 180,347,116 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02174,927,089 - 174,948,007 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02189,045,551 - 189,085,448 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2189,062,443 - 189,083,236 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02208,468,426 - 208,506,275 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42181,935,246 - 181,956,039 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12181,885,351 - 181,906,145 (+)NCBI
Celera2169,097,840 - 169,118,615 (+)NCBICelera
Cytogenetic Map2q34NCBI
ADAR
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381154,582,057 - 154,627,997 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1154,581,695 - 154,628,013 (-)EnsemblGRCh38hg38GRCh38
GRCh371154,554,533 - 154,600,473 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361152,821,157 - 152,867,061 (-)NCBINCBI36Build 36hg18NCBI36
Build 341151,367,612 - 151,393,742NCBI
Celera1127,626,167 - 127,672,093 (-)NCBICelera
Cytogenetic Map1q21.3ENTREZGENE
HuRef1125,917,984 - 125,963,676 (-)NCBIHuRef
CHM1_11155,950,933 - 155,996,946 (-)NCBICHM1_1
T2T-CHM13v2.01153,719,177 - 153,765,142 (-)NCBIT2T-CHM13v2.0
Adar
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39389,622,321 - 89,660,756 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl389,622,329 - 89,660,753 (+)EnsemblGRCm39 Ensembl
GRCm38389,714,469 - 89,753,455 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl389,715,022 - 89,753,446 (+)EnsemblGRCm38mm10GRCm38
MGSCv37389,518,944 - 89,557,377 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36389,800,987 - 89,839,372 (+)NCBIMGSCv36mm8
Celera389,752,022 - 89,790,497 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map339.19NCBI
Adar
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555451,078,319 - 1,106,938 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555451,078,319 - 1,106,938 (-)NCBIChiLan1.0ChiLan1.0
ADAR
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2195,202,292 - 95,251,931 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1194,937,379 - 94,984,250 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01129,937,993 - 129,983,747 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11133,549,380 - 133,595,115 (-)NCBIpanpan1.1PanPan1.1panPan2
ADAR
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1742,762,021 - 42,785,192 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl742,748,136 - 42,782,999 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha742,237,226 - 42,275,953 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0742,632,040 - 42,655,201 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl742,616,310 - 42,655,189 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1742,411,330 - 42,434,458 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0742,449,549 - 42,488,308 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0742,733,156 - 42,771,908 (+)NCBIUU_Cfam_GSD_1.0
Adar
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505825,150,541 - 25,177,944 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365804,183,079 - 4,203,435 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365804,183,016 - 4,208,341 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAR
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl495,154,358 - 95,197,304 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1495,154,230 - 95,197,308 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24103,980,303 - 104,023,300 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAR
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1209,194,611 - 9,241,102 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl209,219,937 - 9,241,329 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660388,533,486 - 8,579,871 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adar
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,812,448 - 2,839,693 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248852,783,058 - 2,839,688 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Adar
232 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:271
Count of miRNA genes:186
Interacting mature miRNAs:208
Transcripts:ENSRNOT00000028181
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)2135552573202446871Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
61457Niddm8Non-insulin dependent diabetes mellitus QTL 84.10.01blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)2174543008175950118Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
61473Bp19Blood pressure QTL 196.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921175950118Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172710921184114403Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168354880185122374Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2114837527185876470Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072175950118Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
6903312Bw112Body weight QTL 1123.20.0013body mass (VT:0001259)body weight (CMO:0000012)2143657569184114274Rat
7488904Bp363Blood pressure QTL 3630.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2172982062175950118Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2143657411190602963Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072185122374Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072185122374Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072185122374Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2152413072185122374Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2152413072185122374Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2152413072175950118Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2152413072175950118Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2152413072175950118Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2152413072175950118Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2152413072175950118Rat

Markers in Region
AI710840  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,177,971 - 175,178,167 (+)MAPPERmRatBN7.2
Rnor_6.02189,085,140 - 189,085,335NCBIRnor6.0
Rnor_5.02208,507,991 - 208,508,186UniSTSRnor5.0
RGSC_v3.42181,957,943 - 181,958,138UniSTSRGSC3.4
Celera2169,120,519 - 169,120,714UniSTS
RH 3.4 Map21155.1UniSTS
Cytogenetic Map2q34UniSTS
AA964848  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,176,904 - 175,177,004 (+)MAPPERmRatBN7.2
Rnor_6.02189,084,073 - 189,084,172NCBIRnor6.0
Rnor_5.02208,506,924 - 208,507,023UniSTSRnor5.0
RGSC_v3.42181,956,876 - 181,956,975UniSTSRGSC3.4
Celera2169,119,452 - 169,119,551UniSTS
RH 3.4 Map21155.2UniSTS
Cytogenetic Map2q34UniSTS
UniSTS:479064  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22175,174,493 - 175,175,950 (+)MAPPERmRatBN7.2
Rnor_6.02189,081,662 - 189,083,118NCBIRnor6.0
Rnor_5.02208,504,513 - 208,505,969UniSTSRnor5.0
RGSC_v3.42181,954,465 - 181,955,921UniSTSRGSC3.4
Celera2169,117,041 - 169,118,497UniSTS
Cytogenetic Map2q34UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 37 21 19 21 74 35 35 11
Low 20 20 20 8 11 6 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_031006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103210 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282624 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128343 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ233433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U18942 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000028181   ⟹   ENSRNOP00000028181
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,155,273 - 175,176,068 (+)Ensembl
Rnor_6.0 Ensembl2189,062,443 - 189,083,236 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000093799   ⟹   ENSRNOP00000090863
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2175,138,403 - 175,178,282 (+)Ensembl
RefSeq Acc Id: NM_031006   ⟹   NP_112268
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,452,964 - 177,473,757 (+)NCBI
mRatBN7.22175,155,273 - 175,176,068 (+)NCBI
Rnor_6.02189,062,443 - 189,083,236 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
RGSC_v3.42181,935,246 - 181,956,039 (+)RGD
Celera2169,097,840 - 169,118,615 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232774   ⟹   XP_006232836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,125 - 177,475,969 (+)NCBI
mRatBN7.22175,138,392 - 175,178,280 (+)NCBI
Rnor_6.02189,045,551 - 189,085,448 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232775   ⟹   XP_006232837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,106 - 177,475,969 (+)NCBI
mRatBN7.22175,138,391 - 175,178,280 (+)NCBI
Rnor_6.02189,045,551 - 189,084,195 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232776   ⟹   XP_006232838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,443,191 - 177,475,969 (+)NCBI
mRatBN7.22175,154,800 - 175,178,280 (+)NCBI
Rnor_6.02189,059,261 - 189,084,195 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232778   ⟹   XP_006232840
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,118 - 177,475,969 (+)NCBI
mRatBN7.22175,138,423 - 175,178,280 (+)NCBI
Rnor_6.02189,045,593 - 189,084,195 (+)NCBI
Rnor_5.02208,468,426 - 208,506,275 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103210   ⟹   XP_038959138
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,106 - 177,475,969 (+)NCBI
mRatBN7.22175,138,391 - 175,178,280 (+)NCBI
RefSeq Acc Id: XM_063282619   ⟹   XP_063138689
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,443,193 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282620   ⟹   XP_063138690
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,443,187 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282621   ⟹   XP_063138691
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,104 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282622   ⟹   XP_063138692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,124 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282623   ⟹   XP_063138693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,436,076 - 177,475,969 (+)NCBI
RefSeq Acc Id: XM_063282624   ⟹   XP_063138694
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82177,459,258 - 177,475,969 (+)NCBI
RefSeq Acc Id: NP_112268   ⟸   NM_031006
- UniProtKB: P55266 (UniProtKB/Swiss-Prot),   A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232837   ⟸   XM_006232775
- Peptide Label: isoform X2
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232836   ⟸   XM_006232774
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AEC1 (UniProtKB/TrEMBL),   A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232840   ⟸   XM_006232778
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_006232838   ⟸   XM_006232776
- Peptide Label: isoform X3
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028181   ⟸   ENSRNOT00000028181
RefSeq Acc Id: XP_038959138   ⟸   XM_039103210
- Peptide Label: isoform X4
- UniProtKB: A6J6H2 (UniProtKB/TrEMBL),   G3V8T3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000090863   ⟸   ENSRNOT00000093799
RefSeq Acc Id: XP_063138693   ⟸   XM_063282623
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063138691   ⟸   XM_063282621
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063138692   ⟸   XM_063282622
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063138690   ⟸   XM_063282620
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063138689   ⟸   XM_063282619
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063138694   ⟸   XM_063282624
- Peptide Label: isoform X10
Protein Domains
A to I editase   DRBM   Z-binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P55266-F1-model_v2 AlphaFold P55266 1-1175 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691481
Promoter ID:EPDNEW_R2006
Type:multiple initiation site
Name:Adar_1
Description:adenosine deaminase, RNA-specific
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02189,062,421 - 189,062,481EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71099 AgrOrtholog
BioCyc Gene G2FUF-52400 BioCyc
Ensembl Genes ENSRNOG00000020744 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028181 ENTREZGENE
  ENSRNOT00000028181.6 UniProtKB/TrEMBL
  ENSRNOT00000093799.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.160.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro A_deamin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAR1_DSRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADAR1_DSRM_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  dsRBD_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zalpha_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:81635 UniProtKB/Swiss-Prot
NCBI Gene 81635 ENTREZGENE
PANTHER DOUBLE-STRANDED RNA-SPECIFIC ADENOSINE DEAMINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EUKARYOTE SPECIFIC DSRNA BINDING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam A_deamin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  dsrm UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  z-alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Adar PhenoGen
PROSITE A_DEAMIN_EDITASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DRADA_REPEAT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DS_RBD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020744 RatGTEx
SMART ADEAMc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DSRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Zalpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP dsRNA-binding domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF46785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6AEC1 ENTREZGENE, UniProtKB/TrEMBL
  A6J6H2 ENTREZGENE, UniProtKB/TrEMBL
  A6J6H3_RAT UniProtKB/TrEMBL
  DSRAD_RAT UniProtKB/Swiss-Prot
  G3V8T3 ENTREZGENE, UniProtKB/TrEMBL
  P55266 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-07-09 Adar  adenosine deaminase, RNA-specific      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_function modifies more frequently the adenosines in AU-rich regions 724707
gene_function modifies viral RNA genomes and may be responsible for hypermutation of certain negative-stranded viruses 724707