Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Crhr2 (corticotropin releasing hormone receptor 2) Rattus norvegicus
Analyze
Symbol: Crhr2
Name: corticotropin releasing hormone receptor 2
Description: Exhibits corticotropin-releasing hormone receptor activity and peptide hormone binding activity. Involved in several processes, including negative regulation of secretion; positive regulation of cell communication; and regulation of gene expression. Localizes to several cellular components, including the cytoplasm; neuron projection; and perikaryon. Used to study colitis; ischemia; and muscular atrophy. Biomarker of colitis; functional colonic disease; irritable bowel syndrome; and mental depression. Human ortholog(s) of this gene implicated in asthma. Orthologous to human CRHR2 (corticotropin releasing hormone receptor 2); PARTICIPATES IN protein kinase A (PKA) signaling pathway; corticotropin-releasing hormone signaling pathway; G protein mediated signaling pathway via Galphas family; INTERACTS WITH (RS)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: corticotrophin releasing hormone receptor 2; corticotropin-releasing factor receptor 2; corticotropin-releasing factor receptor subtype 2; corticotropin-releasing hormone receptor 2; CRF-R 2; CRF-R-2; CRF-R2; CRF2; Crf2r; CRFR-2; CRH-R 2; CRH-R-2; CRH-R2
Orthologs:
Homo sapiens (human) : CRHR2 (corticotropin releasing hormone receptor 2)  HGNC  Alliance
Mus musculus (house mouse) : Crhr2 (corticotropin releasing hormone receptor 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Crhr2 (corticotropin releasing hormone receptor 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CRHR2 (corticotropin releasing hormone receptor 2)
Canis lupus familiaris (dog) : CRHR2 (corticotropin releasing hormone receptor 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Crhr2 (corticotropin releasing hormone receptor 2)
Sus scrofa (pig) : CRHR2 (corticotropin releasing hormone receptor 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0485,286,371 - 85,329,374 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04149,943,615 - 149,986,646 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4483,839,822 - 83,867,017 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1484,085,174 - 84,112,370 (+)NCBI
Celera479,091,140 - 79,118,337 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 5.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Crhr2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70547
Created: 2002-05-20
Species: Rattus norvegicus
Last Modified: 2019-08-06
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.