Skap2 (src kinase associated phosphoprotein 2)

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Gene: Skap2 (src kinase associated phosphoprotein 2) Rattus norvegicus

Analyze

Symbol:

Skap2

Name:

src kinase associated phosphoprotein 2

RGD ID:

620159

Description:

Predicted to be involved in negative regulation of cell population proliferation. Predicted to localize to cytosol; nucleoplasm; and plasma membrane. Orthologous to human SKAP2 (src kinase associated phosphoprotein 2); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Also known as:

Scap2; Scap55r; SKAP-55HOM; SKAP-HOM; SKAP55 homolog; SKAP55-HOM; src family associated phosphoprotein 2; src family-associated phosphoprotein 2; src kinase-associated phosphoprotein 2; src kinase-associated phosphoprotein 55-related protein

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Alliance Genes

More Info

more info ...

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	4	81,816,778 - 81,968,832 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	81,818,569 - 81,968,832 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	146,483,609 - 146,635,663 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	80,149,846 - 80,300,111 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	80,425,975 - 80,576,241 (-)	NCBI
Celera	4	75,843,093 - 75,993,070 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Experimental Liver Cirrhosis (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

4,4'-diaminodiphenylmethane (EXP)

acetamide (EXP)

aflatoxin B2 (ISO)

albendazole (ISO)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

Aroclor 1254 (ISO)

astaxanthin (ISO)

belinostat (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP)

carbamazepine (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

clofibrate (EXP,ISO)

coenzyme Q10 (ISO)

coumestrol (ISO)

curcumin (ISO)

cyclosporin A (ISO)

diethylstilbestrol (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethanol (ISO)

flusilazole (ISO)

folic acid (ISO)

genistein (ISO)

hexaconazole (ISO)

ivermectin (ISO)

lycopene (ISO)

methyl methanesulfonate (ISO)

N-nitrosodimethylamine (EXP)

nickel sulfate (ISO)

O-acetyl-L-carnitine (ISO)

oxycodone (EXP)

panobinostat (ISO)

paracetamol (ISO)

phenylmercury acetate (ISO)

pirinixic acid (ISO)

quercetin (ISO)

resveratrol (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

tamoxifen (ISO)

titanium dioxide (ISO)

toluene (EXP)

triadimefon (ISO)

trichostatin A (ISO)

triclosan (ISO)

tris(2-butoxyethyl) phosphate (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

vinclozolin (EXP)

vitamin E (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

B cell activation (IEA)

negative regulation of cell population proliferation (ISO)

Cellular Component

cytoplasm (IBA,ISO)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

plasma membrane (IBA,ISO)

Molecular Function

protein binding (ISO)

References

References - curated


1.	Curtis DJ, etal., Exp Hematol 2000 Nov;28(11):1250-9.
2.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	MGD data from the GO Consortium
4.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	RGD automated data pipeline
6.	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	RGD automated import pipeline for gene-chemical interactions
8.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:11390434

Genomics

Comparative Map Data

Skap2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rnor_6.0	4	81,816,778 - 81,968,832 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	81,818,569 - 81,968,832 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	146,483,609 - 146,635,663 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	80,149,846 - 80,300,111 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	4	80,425,975 - 80,576,241 (-)	NCBI
Celera	4	75,843,093 - 75,993,070 (-)	NCBI		Celera
Cytogenetic Map	4	q24	NCBI

SKAP2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	7	26,667,068 - 26,995,239 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	7	26,654,772 - 26,864,623 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	7	26,697,397 - 27,034,862 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	26,673,212 - 26,870,866 (-)	NCBI	NCBI36		hg18	NCBI36
Build 34	7	26,479,928 - 26,677,581	NCBI
Celera	7	26,695,659 - 26,893,221 (-)	NCBI
Cytogenetic Map	7	p15.2	NCBI
HuRef	7	26,587,650 - 26,785,497 (-)	NCBI		HuRef
CHM1_1	7	26,706,397 - 26,904,114 (-)	NCBI		CHM1_1
CRA_TCAGchr7v2	7	26,757,875 - 26,955,499 (-)	NCBI

Skap2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	51,836,145 - 51,989,529 (-)	NCBI	GRCm39		mm39
GRCm38	6	51,859,165 - 52,012,549 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	51,857,422 - 52,012,549 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	51,809,164 - 51,962,548 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	6	51,788,748 - 51,942,132 (-)	NCBI			mm8
Celera	6	52,378,898 - 52,532,331 (-)	NCBI		Celera
Cytogenetic Map	6	B3	NCBI

Skap2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955410	28,446,070 - 28,618,450 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955410	28,447,073 - 28,618,450 (-)	NCBI	ChiLan1.0	ChiLan1.0

SKAP2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	7	26,910,341 - 27,106,680 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	26,911,734 - 27,106,285 (-)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	7	27,309,599 - 27,505,842 (-)	NCBI	Mhudiblu_PPA_v0		panPan3

SKAP2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1 Ensembl	14	39,916,343 - 40,092,188 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
CanFam3.1	14	39,914,285 - 40,261,782 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1

Skap2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
SpeTri2.0	NW_004936478	3,393,425 - 3,566,214 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SKAP2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	45,562,381 - 45,790,259 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	45,636,929 - 45,813,748 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

SKAP2
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	31,499,084 - 31,698,663 (+)	NCBI

Position Markers

D4Rat33

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	81,874,073 - 81,874,227	NCBI	Rnor6.0
Rnor_5.0	4	146,540,904 - 146,541,058	UniSTS	Rnor5.0
RGSC_v3.4	4	80,205,349 - 80,205,504	RGD	RGSC3.4
RGSC_v3.4	4	80,205,350 - 80,205,504	UniSTS	RGSC3.4
RGSC_v3.1	4	80,481,479 - 80,481,634	RGD
Celera	4	75,898,515 - 75,898,669	UniSTS
Cytogenetic Map	4	q24	UniSTS
RH 3.4 Map	4	512.42	UniSTS
RH 3.4 Map	4	512.42	RGD
RH 2.0 Map	4	546.7	RGD
SHRSP x BN Map	4	40.85	RGD
FHH x ACI Map	4	47.95	RGD

RH134516

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	81,818,719 - 81,818,916	NCBI	Rnor6.0
Rnor_5.0	4	146,485,550 - 146,485,747	UniSTS	Rnor5.0
RGSC_v3.4	4	80,149,996 - 80,150,193	UniSTS	RGSC3.4
Celera	4	75,843,243 - 75,843,440	UniSTS
Cytogenetic Map	4	q24	UniSTS
RH 3.4 Map	4	512.31	UniSTS

AU046691

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_6.0	4	81,874,042 - 81,874,322	NCBI	Rnor6.0
Rnor_5.0	4	146,540,873 - 146,541,153	UniSTS	Rnor5.0
RGSC_v3.4	4	80,205,319 - 80,205,599	UniSTS	RGSC3.4
Celera	4	75,898,484 - 75,898,764	UniSTS
Cytogenetic Map	4	q24	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	3043231	145254791	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	7342404	92484039	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	7850904	182171018	Rat
10755501	Bp390	Blood pressure QTL 390	2.5		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	23850384	169318094	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	26654749	81874227	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	29549895	112807890	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	31825560	83531021	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	31825560	83531021	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	31825560	83531021	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	34277932	99067150	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	36615599	145611886	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	37703272	115372927	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	39208222	84208222	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	39208247	84208247	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	42415777	87415777	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	43414605	155469929	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	43414792	146942075	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	43414792	146942075	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	46898276	145611886	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	49906054	145611886	Rat
70200	Alc18	Alcohol consumption QTL 18	9.2		drinking behavior trait (VT:0001422)	ethanol intake volume to total fluid intake volume ratio (CMO:0001591)	4	55324953	148360954	Rat
1641833	Alc21	Alcohol consumption QTL 21	8.6	0.0001	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	55375865	125671711	Rat
634311	Sach7	Saccharin preference QTL 7			taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	55791564	82134846	Rat
631546	Bp86	Blood pressure QTL 86	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	55791564	92484312	Rat
1578657	Bss12	Bone structure and strength QTL 12	8.9		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	4	56092756	101092756	Rat
1578658	Bss13	Bone structure and strength QTL 13	8		femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	4	56092756	101092756	Rat
1558651	Swd3	Spike wave discharge measurement QTL 3	4.62	0.000024	brain electrophysiology trait (VT:0010557)	brain spike-and-wave discharge frequency (CMO:0001742)	4	57101077	92990863	Rat
1358363	Sradr3	Stress Responsive Adrenal Weight QTL 3	6.19		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	4	58166424	103166424	Rat
738009	Sach4	Saccharine consumption QTL 4	4.9	0.000016	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	4	58640017	154427984	Rat
738016	Alc16	Alcohol consumption QTL 16	3.6	0.00015	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	58640017	154427984	Rat
738031	Alc14	Alcohol consumption QTL 14	7.6	0.00003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	4	58640017	154427984	Rat
1549843	Bw53	Body weight QTL 53		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	60439127	99066957	Rat
1549839	Bw52	Body weight QTL 52		0.0001	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	60439127	113416139	Rat
61418	Pia5	Pristane induced arthritis QTL 5	4.5		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	61038901	127777403	Rat
7394826	Bw126	Body weight QTL 126		0.002	body mass (VT:0001259)	body weight gain (CMO:0000420)	4	61708103	88565113	Rat
8552807	Vie4	Viral induced encephalitis QTL 4	7.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	61708341	83531021	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	percent change in mean arterial blood pressure (CMO:0002035)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	percent change in systolic blood pressure (CMO:0000747)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in pulse pressure (CMO:0001882)	4	61708341	113100992	Rat
70192	BpQTLcluster5	Blood pressure QTL cluster 5	4.183		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	4	61708341	113100992	Rat
2300179	Bmd50	Bone mineral density QTL 50	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	4	61975371	106975371	Rat
1641919	Alc22	Alcohol consumption QTL 22		0.0005	drinking behavior trait (VT:0001422)	ethanol drink intake rate (CMO:0001407)	4	62947687	125671711	Rat
631674	Iddm14	Insulin dependent diabetes mellitus QTL 14			blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	4	63537179	157286626	Rat
6478684	Anxrr30	Anxiety related response QTL 30		0.00087	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	63812687	108812687	Rat
6478743	Anxrr40	Anxiety related response QTL 40		0.83076	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	63812687	108812687	Rat
6478772	Anxrr49	Anxiety related response QTL 49		0.15488	defecation behavior trait (VT:0010462)	defecation rate (CMO:0000998)	4	63812687	108812687	Rat
631651	Bp124	Blood pressure QTL 124	3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	63938412	108938412	Rat
2312569	Pur19	Proteinuria QTL 19	3.4	0.001	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	4	65989243	97759057	Rat
61330	Eau1	Experimental allergic uveoretinitis QTL 1		0.0003	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	4	70773471	132455556	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion area to total liver area ratio (CMO:0001075)	4	71476518	116476518	Rat
634344	Hcar7	Hepatocarcinoma resistance QTL 7	7.8		liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	4	71476518	116476518	Rat
631646	Stl4	Serum triglyceride level QTL 4	6.5	0.0001	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	4	73786419	132455556	Rat
724522	Bp146	Blood pressure QTL 146	2.2	0.0021	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	75258970	120258970	Rat
2302051	Pia28	Pristane induced arthritis QTL 28	5.3	0.001	blood autoantibody amount (VT:0003725)	serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)	4	75258970	120258970	Rat
738015	Pia9	Pristane induced arthritis QTL 9	4.5	0.048	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	76567036	121567036	Rat
70167	Bw22	Body weight QTL 22	3.1		body mass (VT:0001259)	body weight (CMO:0000012)	4	77307388	116916073	Rat
1357342	Bw40	Body weight QTL 40		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	4	77307388	116916073	Rat
631662	Hcar2	Hepatocarcinoma resistance QTL 2	3.1	0.0003	liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	4	79555067	124555067	Rat
631556	Bp135	Blood pressure QTL 135		0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	79557856	116916073	Rat
2317586	Eae25	Experimental allergic encephalomyelitis QTL 25	9.300000190734863		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	4	79559380	84053053	Rat
2317586	Eae25	Experimental allergic encephalomyelitis QTL 25	9.300000190734863		nervous system integrity trait (VT:0010566)	percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)	4	79559380	84053053	Rat
2317586	Eae25	Experimental allergic encephalomyelitis QTL 25	9.300000190734863		nervous system integrity trait (VT:0010566)	post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)	4	79559380	84053053	Rat
2317586	Eae25	Experimental allergic encephalomyelitis QTL 25	9.300000190734863		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	4	79559380	84053053	Rat
61364	Iddm2	Insulin dependent diabetes mellitus QTL 2			blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	79562451	98542106	Rat
2306899	Bp338	Blood pressure QTL 338		0.071	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	81874073	119546974	Rat
70177	Xhs1	X-ray hypersensitivity QTL 1	25.1		intestine integrity trait (VT:0010554)	post-insult time to onset of moribundity (CMO:0001896)	4	81959983	152055009	Rat

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	52
Count of miRNA genes:	43
Interacting mature miRNAs:	49
Transcripts:	ENSRNOT00000016608
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	16	57	41	19	41	1	1	50	35	41	11	1
Low		27					7	10	24				7
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_130413	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236478	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017592411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAHX01030181	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01030182	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01030183	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AAHX01030184	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC096072	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF302132	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC070949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000016608 ⟹ ENSRNOP00000016608

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	4	81,818,569 - 81,968,832 (-)	Ensembl

RefSeq Acc Id:

NM_130413 ⟹ NP_569097

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	81,818,569 - 81,968,832 (-)	NCBI
Rnor_5.0	4	146,483,609 - 146,635,663 (-)	NCBI
RGSC_v3.4	4	80,149,846 - 80,300,111 (-)	RGD
Celera	4	75,843,093 - 75,993,070 (-)	RGD

Sequence:

show sequence

CGGCGTCCAGCGACCGCTGCCTGGACAGCCAGTGACTTCCTTGTTGTGGGTCTCGGCCAGGTCG
TGTCCCGAGTCGTAGCCCCGCGGTGCTTACTCGGACCGCTTTTGCAAGTCTAGGTCCAAGCTAC
TACCATGCCCAACCCCGGCAGTACCTCCTCTCCCGGCTCAATCCCTGAGGAAATTAGGAACCTG
TTGGCAGATGTTGAAACATTTGTGGCAGACACACTGAAAGGGGAAAATTTATCCAAGAAAGCCA
AGGAAAAGAGAGACTCTCTCATTAAGAAGATAAAAGATGTAAAGTCTGTCTATCCTCAGGAATT
TCAAGACAAAGGTGATGCCGAGGAGGGGGATGAATATGATGATCCTTTTGCTGGGCCTCCAGAC
ACGATTTCCTTAGCCTCAGAACGCTATGACAAAGATGACGATGGCCCCTCTGATGGAAACCAGT
TTCCTCCCATTGCAGCCCAGGACCTTTCTTTTGTCATAAAGGCTGGTTACCTGGAAAAACGCAG
AAAAGATCACAGCTTTCTGGGGTTTGAATGGCAGAAACGGTGGTGTGCTCTCAGCAAAACAGTG
TTCTATTATTACGGGAGTGATAAAGACAAACAACAGAAAGGGGAATTTGCCATAGAGGGCTATG
ACGTCAGAATGAACAACACCCTTAGGAAGGATGCAAAGAAAGATTGCTGTTTCGAAATCTGTGC
TCCCGATAAACGTATCTATCAGTTTACAGCAGCCTCTCCCAAAGATGCTGAGGAATGGGTCCAG
CAGCTGAAATTCATATTACAAGACATGGGATCTGACGTTATTCCCGAGGATGAAGATGAAAAAG
GGGACTTATATGATGATGTTGATCATCCTGTTCCGGTCAGCAGCCCACAAAGGAGCCAACCAAT
AGATGATGAAATTTATGAGGAACTTCCAGAGGAGGAAGAGGACACCGCTTCAGTGAAGATGGAC
GAACAAGGGAAGGGGAGTCGGGACAGTGTACAGCATCCCTCAGGAGATAAAAGCACCGATTATG
CTAATTTTTACCAGGGCTTGTGGGACTGCACTGGATCTCTTTCTGATGAGTTGTCCTTTAAGCG
TGGTGATGTGATTTACATTCTTAGCAAGGAATACAATAGATATGGCTGGTGGGTAGGAGAAATG
CAGGGAGCCATTGGCTTGGTGCCTAAAGCCTACCTAATGGAGATGTATGATATTTGAGAGTCTG
GGAGAAATAAATCAACATTTCTACTGAAGAAAACAAAACTTAAATGTAGCTTTCCCCTTTTGCT
GGCACAGAAGTCTGTCCATCTGCAAGCGCTTTGGAACACAGACTGCCTGGAGCCACCTTCCTTT
GGGAGACCTTCCTGCCTCAGCTGTCGTCCTGTGTCGTCATTCACTAAAGCTCCTGACGTCAGAT
TAAGCAAGCAGTGATGGGTTACATTAGAGACAAGCCGCAGAGATAAGGCCTGTTGCTGTTTCGC
AGATAATGATGAGTTTTAATTTACCCACTGGTTTGTATGGGGAATTCATTGTGATTGTATCTGA
ATCTTAGTCATTGAAGCCACCACTGAAGGTTGCTGTTTCTCGTAGTCACTGGGTTATTTTTAGA
GTGCCACATATAATTTCCTAAACTTTGT

hide sequence

RefSeq Acc Id:

XM_006236477 ⟹ XP_006236539

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	81,816,778 - 81,968,814 (-)	NCBI
Rnor_5.0	4	146,483,609 - 146,635,663 (-)	NCBI

Sequence:

show sequence

GCCTGGACAGCCAGTGACTTCCTTGTTGTGGGTCTCGGCCAGGTCGTGTCCCGAGTCGTAGCCC
CGCGGTGCTTACTCGGACCGCTTTTGCAAGTCTAGGTCCAAGCTACTACCATGCCCAACCCCGG
CAGTACCTCCTCTCCCGGCTCAATCCCTGAGGAAATTAGGAACCTGTTGGCAGATGTTGAAACA
TTTGTGGCAGACACACTGAAAGGGGAAAATTTATCCAAGAAAGCCAAGGAAAAGAGAGACTCTC
TCATTAAGAAGATAAAAGATGTAAAGTCTGTCTATCCTCAGGAATTTCAAGACAAAGGTGATGC
CGAGGAGGGGGATGAATATGATGATCCTTTTGCTGGGCCTCCAGACACGATTTCCTTAGCCTCA
GAACGCTATGACAAAGATGACGATGGCCCCTCTGATGGAAACCAGTTTCCTCCCATTGCAGCCC
AGGACCTTTCTTTTGTCATAAAGGCTGGTTACCTGGAAAAACGCAGAAAAGATCACAGCTTTCT
GGGGTTTGAATGGCAGAAACGGTGGTGTGCTCTCAGCAAAACAGTGTTCTATTATTACGGGAGT
GATAAAGACAAACAACAGAAAGGGGAATTTGCCATAGAGGGCTATGACGTCAGAATGAACAACA
CCCTTAGGAAGGATGCAAAGAAAGATTGCTGTTTCGAAATCTGTGCTCCCGATAAACGTATCTA
TCAGTTTACAGCAGCCTCTCCCAAAGATGCTGAGGAATGGGTCCAGCAGCTGAAATTCATATTA
CAAGACATGGGATCTGACGTTATTCCCGAGGATGAAGATGAAAAAGGGGACTTATATGATGATG
TTGATCATCCTGTTCCGGTCAGCAGCCCACAAAGGAGCCAACCAATAGATGATGAAATTTATGA
GGAACTTCCAGAGGAGGAAGAGGACACCGCTTCAGTGAAGATGGACGAACAAGGGAAGGGGAGT
CGGGACAGTGTACAGCATCCCTCAGGAGATAAAAGCACCGATTATGCTAATTTTTACCAGGGCT
TGTGGGACTGCACTGGATCTCTTTCTGATGAGTTGTCCTTTAAGCGTGGTGATGTGATTTACAT
TCTTAGCAAGGAATACAATAGATATGGCTGGTGGGTAGGAGAAATGCAGGGAGCCATTGGCTTG
GTGCCTAAAGCCTACCTAATGGAGATGTATGATATTTGAGAGTCTGGCAGGAGAAATAAATCAA
CATTTCTACTGAAGAAAACAAAACTTAAATGTAGCTTTCCCCTTTTGCTGGCACAGAAGTCTGT
CCATCTGCAAGCGCTTTGGAACACAGACTGCCTGGAGCCACCTTCCTTTGGGAGACCTTCCTGC
CTCAGCTGTCGTCCTGTGTCGTCATTCACTAAAGCTCCTGACGTCAGATTAAGCAAGCAGTGAT
GGGTTACATTAGAGACAAGCCGCAGAGATAAGGCCTGTTGCTGTTTCGCAGATAATGATGAGTT
TTAATTTACCCACTGGTTTGTATGGGGAATTCATTGTGATTGTATCTGAATCTTAGTCATTGAA
GCCACCACTGAAGGTTGCTGTTTCTCGTAGTCACTGGGTTATTTTTAGAGTGCCACATATAATT
TCCTAAACTTTGTACATTTTGAGTCAATAATAAAGACTTCGTTAAAGCTGTATAGATGACTTAG
CTTGGTACTTTATTCTTCCTAGAGTAATAACATGTTTTCATTAAAGAAGTTGTACGGACTCACA
GGTTTACCTACTGCTAGGTAAGAAAGCGAAAACGATCACTTGCATTACGGATAGAGGGACGGTG
GCAGCCTGCTGTCAGCCCCTGCACAGAGCAAACCAGAGCTGGGTTTCTGAAAGCACTTGGGTAT
CCTAATTTGATGATGAGCTTGTCAGTGTTTCCTAATGTAATTTTATTTAAATTTAATGAAATCA
AAGATTCATAAGAAACCCCGTTTTACCACTAATACAATGGTATAAACAACTTGAGCATGTTTTC
AGAGTCCGAGGGCGCGCCAGGTACTCTCTGAGCGCTCTGACTCTTCCTGGCAGAGTCCTGTCGC
AGTCCCGGCCTACAGCAGCCCTGGCGGAAGCTCCTGTGAGCGTCTCTGAACCAAATGGAAAAGA
ATGGTAACAGGTCCCAGCAGGGGAAGGGAAGTGAAGGCCGACCTGCTGTCTGATACTATTTGTT
GCTGCATGGGTAAGGTTTGCAGAATCCTGACAGTGGTCTTTCATATAATGTTAAAATCAGAGCA
TTCCCAATCATCTAGAGACGCCACGATAGCCTTACTCTGTATTAAACGCACTAGTGACTAGATA
TTTTGGAGTAAATGGAATCTACTCTTGAATCATTCTTTAGCAGGCCCTCACTTAAGCTTAACTT
TTCAGGTGGGAATGAAAATAGGCCAATAATATTTTTTAATTCTGCACTATTTACAAGCAATAGT
AAAGAGTGTTTATTTTACTGTTTATTTTACTGTCATATTATACATACTGTGATCACTCATTTTC
CAAAGTAAAAGAAAAAACAAATCTTAAGTTGACCCGTGTAGACATAGTCCGAGTTTTCAGAAAC
TGCATTTGTACGGTTACCCATTTCCTACTAAAGTGTCATCTAAGTAGGTTGAAATCATCTTGGC
AAAATTTGGCAGGCAGAAATGAATTCAGTGGGCCGCCTTTCAGAGGCTGACTGAGCCTGCACGG
TGGAGACAGGCAAAGCCTGTGCTGTGGTTACAGGTTTGGTGCCTTTAAGTTAAGGAGCCAGCAG
ATGGCAGCAGCTGTCATCTGCACACGGACACACTTGAGGACCCCCTCCCCCACGCCAGCCGTCC
AAGAAGCAGGTTTGTGTCTCCTTTTCCAGTTAAGCCAGGAGAGGGAGTCCTTTGCCAACTGATG
GCCAACGTTTCCAGCACAGAAGCTGCTTCTGTCCACAGCCTCTGGCCTTTGTTCTTTTTTTTTA
ACTCGAATATACACGGGAGGTAGAAGATGGGAACCAAAGGCCTTTAAATCTGGGAGAGATGAGA
AAAACTGCCGCTCCCCGTGCTGCAAGTGTGCCTTTCTGTTCAGTCGGTAAACTCATCTTTGTGC
TGTGAGGAAGTTTCTCTCTACCCTTGACAGTACATCACATTCTCCTCAAGATCATAATAACATC
ATTAATGTGAATTTAAACAACGCGGCTTGTTAGAAAACATGCTAATTGTTATGTTCTCATTATG
TTTGCATAGCTTTTATTTGTTTTCCTATGAACGGTTAGAGAGCTAATTTTTCTGAAAGGTGATT
GTGAGTCATATTTTATATGGCATTTTGCTTGATCGTTTGCTCCGCACTGAATTTGTACTCCGTC
GCCATTAGATCTTACAATAATGTTCCACTCTGCAAATTTTTAAGGTTCAAATAAAGTTTAATTG
TTTGCAAACTGT

hide sequence

RefSeq Acc Id:

XM_006236478 ⟹ XP_006236540

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	81,816,778 - 81,968,814 (-)	NCBI
Rnor_5.0	4	146,483,609 - 146,635,663 (-)	NCBI

Sequence:

show sequence

GCCTGGACAGCCAGTGACTTCCTTGTTGTGGGTCTCGGCCAGGTCGTGTCCCGAGTCGTAGCCC
CGCGGTGCTTACTCGGACCGCTTTTGCAAGTCTAGGTCCAAGCTACTACCATGCCCAACCCCGG
CAGTACCTCCTCTCCCGGCTCAATCCCTGAGGAAATTAGGAACCTGTTGGCAGATGTTGAAACA
TTTGTGGCAGACACACTGAAAGGGGAAAATTTATCCAAGAAAGCCAAGGAAAAGAGAGACTCTC
TCATTAAGAAGATAAAAGATGTAAAGTCTGTCTATCCTCAGGAATTTCAAGACAAAGGTGATGC
CGAGGAGGGGGATGAATATGATGATCCTTTTGCTGGGCCTCCAGACACGATTTCCTTAGCCTCA
GAACGCTATGACAAAGATGACGATGGCCCCTCTGATGGAAACCAGTTTCCTCCCATTGCAGCCC
AGGACCTTTCTTTTGTCATAAAGGCTGGTTACCTGGAAAAACGCAGAAAAGATCACAGCTTTCT
GGGGTTTGAATGGCAGAAACGGTGGTGTGCTCTCAGCAAAACAGTGTTCTATTATTACGGGAGT
GATAAAGACAAACAACAGAAAGGGGAATTTGCCATAGAGGGCTATGACGTCAGAATGAACAACA
CCCTTAGGAAGGATGCAAAGAAAGATTGCTGTTTCGAAATCTGTGCTCCCGATAAACGTATCTA
TCAGTTTACAGCAGCCTCTCCCAAAGATGCTGAGGAATGGGTCCAGCAGCTGAAATTCATATTA
CAAGACATGGGATCTGACGTTATTCCCGAGGATGAAGATGAAAAAGGGGACTTATATGATGATG
TTGATCATCCTGTTCCGGTCAGCAGCCCACAAAGGAGCCAACCAATAGATGATGAAATTTATGA
GGAACTTCCAGAGGAGGAAGAGGACACCGCTTCAGTGAAGATGGACGAACAAGGGAAGGGGAGT
CGGGACAGTGTACAGCATCCCTCAGGAGATAAAAGCACCGATTATGCTAATTTTTACCAGGGCT
TGTGGGACTGCACTGGATCTCTTTCTGATGAGTTGTCCTTTAAGCGTGGTGATGTGATTTACAT
TCTTAGCAAGGAATACAATAGATATGGCTGGTGGGTAGGAGAAATGCAGGGAGCCATTGGCTTG
GTGCCTAAAGCCTACCTAATGGAGATGTATGATATTTGAGAGTCTGGAAGTCTGTCCATCTGCA
AGCGCTTTGGAACACAGACTGCCTGGAGCCACCTTCCTTTGGGAGACCTTCCTGCCTCAGCTGT
CGTCCTGTGTCGTCATTCACTAAAGCTCCTGACGTCAGATTAAGCAAGCAGTGATGGGTTACAT
TAGAGACAAGCCGCAGAGATAAGGCCTGTTGCTGTTTCGCAGATAATGATGAGTTTTAATTTAC
CCACTGGTTTGTATGGGGAATTCATTGTGATTGTATCTGAATCTTAGTCATTGAAGCCACCACT
GAAGGTTGCTGTTTCTCGTAGTCACTGGGTTATTTTTAGAGTGCCACATATAATTTCCTAAACT
TTGTACATTTTGAGTCAATAATAAAGACTTCGTTAAAGCTGTATAGATGACTTAGCTTGGTACT
TTATTCTTCCTAGAGTAATAACATGTTTTCATTAAAGAAGTTGTACGGACTCACAGGTTTACCT
ACTGCTAGGTAAGAAAGCGAAAACGATCACTTGCATTACGGATAGAGGGACGGTGGCAGCCTGC
TGTCAGCCCCTGCACAGAGCAAACCAGAGCTGGGTTTCTGAAAGCACTTGGGTATCCTAATTTG
ATGATGAGCTTGTCAGTGTTTCCTAATGTAATTTTATTTAAATTTAATGAAATCAAAGATTCAT
AAGAAACCCCGTTTTACCACTAATACAATGGTATAAACAACTTGAGCATGTTTTCAGAGTCCGA
GGGCGCGCCAGGTACTCTCTGAGCGCTCTGACTCTTCCTGGCAGAGTCCTGTCGCAGTCCCGGC
CTACAGCAGCCCTGGCGGAAGCTCCTGTGAGCGTCTCTGAACCAAATGGAAAAGAATGGTAACA
GGTCCCAGCAGGGGAAGGGAAGTGAAGGCCGACCTGCTGTCTGATACTATTTGTTGCTGCATGG
GTAAGGTTTGCAGAATCCTGACAGTGGTCTTTCATATAATGTTAAAATCAGAGCATTCCCAATC
ATCTAGAGACGCCACGATAGCCTTACTCTGTATTAAACGCACTAGTGACTAGATATTTTGGAGT
AAATGGAATCTACTCTTGAATCATTCTTTAGCAGGCCCTCACTTAAGCTTAACTTTTCAGGTGG
GAATGAAAATAGGCCAATAATATTTTTTAATTCTGCACTATTTACAAGCAATAGTAAAGAGTGT
TTATTTTACTGTTTATTTTACTGTCATATTATACATACTGTGATCACTCATTTTCCAAAGTAAA
AGAAAAAACAAATCTTAAGTTGACCCGTGTAGACATAGTCCGAGTTTTCAGAAACTGCATTTGT
ACGGTTACCCATTTCCTACTAAAGTGTCATCTAAGTAGGTTGAAATCATCTTGGCAAAATTTGG
CAGGCAGAAATGAATTCAGTGGGCCGCCTTTCAGAGGCTGACTGAGCCTGCACGGTGGAGACAG
GCAAAGCCTGTGCTGTGGTTACAGGTTTGGTGCCTTTAAGTTAAGGAGCCAGCAGATGGCAGCA
GCTGTCATCTGCACACGGACACACTTGAGGACCCCCTCCCCCACGCCAGCCGTCCAAGAAGCAG
GTTTGTGTCTCCTTTTCCAGTTAAGCCAGGAGAGGGAGTCCTTTGCCAACTGATGGCCAACGTT
TCCAGCACAGAAGCTGCTTCTGTCCACAGCCTCTGGCCTTTGTTCTTTTTTTTTAACTCGAATA
TACACGGGAGGTAGAAGATGGGAACCAAAGGCCTTTAAATCTGGGAGAGATGAGAAAAACTGCC
GCTCCCCGTGCTGCAAGTGTGCCTTTCTGTTCAGTCGGTAAACTCATCTTTGTGCTGTGAGGAA
GTTTCTCTCTACCCTTGACAGTACATCACATTCTCCTCAAGATCATAATAACATCATTAATGTG
AATTTAAACAACGCGGCTTGTTAGAAAACATGCTAATTGTTATGTTCTCATTATGTTTGCATAG
CTTTTATTTGTTTTCCTATGAACGGTTAGAGAGCTAATTTTTCTGAAAGGTGATTGTGAGTCAT
ATTTTATATGGCATTTTGCTTGATCGTTTGCTCCGCACTGAATTTGTACTCCGTCGCCATTAGA
TCTTACAATAATGTTCCACTCTGCAAATTTTTAAGGTTCAAATAAAGTTTAATTGTTTGCAAAC
TGT

hide sequence

RefSeq Acc Id:

XM_017592411 ⟹ XP_017447900

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	81,816,782 - 81,882,922 (-)	NCBI

Sequence:

show sequence

CTCCTTTCTGTTATCAGTGTTGTGAAGACCTGGGGAAATTCCTAGGAACACCAGTGAAGTTACT
GAGTGACCTGGCACATGTTACCATGAGTTTCTAACATGAAACCAGTTTCCTCCCATTGCAGCCC
AGGACCTTTCTTTTGTCATAAAGGCTGGTTACCTGGAAAAACGCAGAAAAGATCACAGCTTTCT
GGGGTTTGAATGGCAGAAACGGTGGTGTGCTCTCAGCAAAACAGTGTTCTATTATTACGGGAGT
GATAAAGACAAACAACAGAAAGGGGAATTTGCCATAGAGGGCTATGACGTCAGAATGAACAACA
CCCTTAGGAAGGATGCAAAGAAAGATTGCTGTTTCGAAATCTGTGCTCCCGATAAACGTATCTA
TCAGTTTACAGCAGCCTCTCCCAAAGATGCTGAGGAATGGGTCCAGCAGCTGAAATTCATATTA
CAAGACATGGGATCTGACGTTATTCCCGAGGATGAAGATGAAAAAGGGGACTTATATGATGATG
TTGATCATCCTGTTCCGGTCAGCAGCCCACAAAGGAGCCAACCAATAGATGATGAAATTTATGA
GGAACTTCCAGAGGAGGAAGAGGACACCGCTTCAGTGAAGATGGACGAACAAGGGAAGGGGAGT
CGGGACAGTGTACAGCATCCCTCAGGAGATAAAAGCACCGATTATGCTAATTTTTACCAGGGCT
TGTGGGACTGCACTGGATCTCTTTCTGATGAGTTGTCCTTTAAGCGTGGTGATGTGATTTACAT
TCTTAGCAAGGAATACAATAGATATGGCTGGTGGGTAGGAGAAATGCAGGGAGCCATTGGCTTG
GTGCCTAAAGCCTACCTAATGGAGATGTATGATATTTGAGAGTCTGGGAGAAATAAATCAACAT
TTCTACTGAAGAAAACAAAACTTAAATGTAGCTTTCCCCTTTTGCTGGCACAGAAGTCTGTCCA
TCTGCAAGCGCTTTGGAACACAGACTGCCTGGAGCCACCTTCCTTTGGGAGACCTTCCTGCCTC
AGCTGTCGTCCTGTGTCGTCATTCACTAAAGCTCCTGACGTCAGATTAAGCAAGCAGTGATGGG
TTACATTAGAGACAAGCCGCAGAGATAAGGCCTGTTGCTGTTTCGCAGATAATGATGAGTTTTA
ATTTACCCACTGGTTTGTATGGGGAATTCATTGTGATTGTATCTGAATCTTAGTCATTGAAGCC
ACCACTGAAGGTTGCTGTTTCTCGTAGTCACTGGGTTATTTTTAGAGTGCCACATATAATTTCC
TAAACTTTGTACATTTTGAGTCAATAATAAAGACTTCGTTAAAGCTGTATAGATGACTTAGCTT
GGTACTTTATTCTTCCTAGAGTAATAACATGTTTTCATTAAAGAAGTTGTACGGACTCACAGGT
TTACCTACTGCTAGGTAAGAAAGCGAAAACGATCACTTGCATTACGGATAGAGGGACGGTGGCA
GCCTGCTGTCAGCCCCTGCACAGAGCAAACCAGAGCTGGGTTTCTGAAAGCACTTGGGTATCCT
AATTTGATGATGAGCTTGTCAGTGTTTCCTAATGTAATTTTATTTAAATTTAATGAAATCAAAG
ATTCATAAGAAACCCCGTTTTACCACTAATACAATGGTATAAACAACTTGAGCATGTTTTCAGA
GTCCGAGGGCGCGCCAGGTACTCTCTGAGCGCTCTGACTCTTCCTGGCAGAGTCCTGTCGCAGT
CCCGGCCTACAGCAGCCCTGGCGGAAGCTCCTGTGAGCGTCTCTGAACCAAATGGAAAAGAATG
GTAACAGGTCCCAGCAGGGGAAGGGAAGTGAAGGCCGACCTGCTGTCTGATACTATTTGTTGCT
GCATGGGTAAGGTTTGCAGAATCCTGACAGTGGTCTTTCATATAATGTTAAAATCAGAGCATTC
CCAATCATCTAGAGACGCCACGATAGCCTTACTCTGTATTAAACGCACTAGTGACTAGATATTT
TGGAGTAAATGGAATCTACTCTTGAATCATTCTTTAGCAGGCCCTCACTTAAGCTTAACTTTTC
AGGTGGGAATGAAAATAGGCCAATAATATTTTTTAATTCTGCACTATTTACAAGCAATAGTAAA
GAGTGTTTATTTTACTGTTTATTTTACTGTCATATTATACATACTGTGATCACTCATTTTCCAA
AGTAAAAGAAAAAACAAATCTTAAGTTGACCCGTGTAGACATAGTCCGAGTTTTCAGAAACTGC
ATTTGTACGGTTACCCATTTCCTACTAAAGTGTCATCTAAGTAGGTTGAAATCATCTTGGCAAA
ATTTGGCAGGCAGAAATGAATTCAGTGGGCCGCCTTTCAGAGGCTGACTGAGCCTGCACGGTGG
AGACAGGCAAAGCCTGTGCTGTGGTTACAGGTTTGGTGCCTTTAAGTTAAGGAGCCAGCAGATG
GCAGCAGCTGTCATCTGCACACGGACACACTTGAGGACCCCCTCCCCCACGCCAGCCGTCCAAG
AAGCAGGTTTGTGTCTCCTTTTCCAGTTAAGCCAGGAGAGGGAGTCCTTTGCCAACTGATGGCC
AACGTTTCCAGCACAGAAGCTGCTTCTGTCCACAGCCTCTGGCCTTTGTTCTTTTTTTTTAACT
CGAATATACACGGGAGGTAGAAGATGGGAACCAAAGGCCTTTAAATCTGGGAGAGATGAGAAAA
ACTGCCGCTCCCCGTGCTGCAAGTGTGCCTTTCTGTTCAGTCGGTAAACTCATCTTTGTGCTGT
GAGGAAGTTTCTCTCTACCCTTGACAGTACATCACATTCTCCTCAAGATCATAATAACATCATT
AATGTGAATTTAAACAACGCGGCTTGTTAGAAAACATGCTAATTGTTATGTTCTCATTATGTTT
GCATAGCTTTTATTTGTTTTCCTATGAACGGTTAGAGAGCTAATTTTTCTGAAAGGTGATTGTG
AGTCATATTTTATATGGCATTTTGCTTGATCGTTTGCTCCGCACTGAATTTGTACTCCGTCGCC
ATTAGATCTTACAATAATGTTCCACTCTGCAAATTTTTAAGGTTCAAATAAAGTTTAATTGTTT
GCAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_569097	(Get FASTA)	NCBI Sequence Viewer
	XP_006236539	(Get FASTA)	NCBI Sequence Viewer
	XP_006236540	(Get FASTA)	NCBI Sequence Viewer
	XP_017447900	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH70949	(Get FASTA)	NCBI Sequence Viewer
	AAK97262	(Get FASTA)	NCBI Sequence Viewer
	EDL88171	(Get FASTA)	NCBI Sequence Viewer
	EDL88172	(Get FASTA)	NCBI Sequence Viewer
	Q920G0	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_569097 ⟸ NM_130413

- UniProtKB:

Q920G0 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MPNPGSTSSPGSIPEEIRNLLADVETFVADTLKGENLSKKAKEKRDSLIKKIKDVKSVYPQEFQ
DKGDAEEGDEYDDPFAGPPDTISLASERYDKDDDGPSDGNQFPPIAAQDLSFVIKAGYLEKRRK
DHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIEGYDVRMNNTLRKDAKKDCCFEICAP
DKRIYQFTAASPKDAEEWVQQLKFILQDMGSDVIPEDEDEKGDLYDDVDHPVPVSSPQRSQPID
DEIYEELPEEEEDTASVKMDEQGKGSRDSVQHPSGDKSTDYANFYQGLWDCTGSLSDELSFKRG
DVIYILSKEYNRYGWWVGEMQGAIGLVPKAYLMEMYDI

hide sequence

RefSeq Acc Id:	XP_006236540 ⟸ XM_006236478
- Peptide Label:	isoform X1
- UniProtKB:	Q920G0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MPNPGSTSSPGSIPEEIRNLLADVETFVADTLKGENLSKKAKEKRDSLIKKIKDVKSVYPQEFQ DKGDAEEGDEYDDPFAGPPDTISLASERYDKDDDGPSDGNQFPPIAAQDLSFVIKAGYLEKRRK DHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIEGYDVRMNNTLRKDAKKDCCFEICAP DKRIYQFTAASPKDAEEWVQQLKFILQDMGSDVIPEDEDEKGDLYDDVDHPVPVSSPQRSQPID DEIYEELPEEEEDTASVKMDEQGKGSRDSVQHPSGDKSTDYANFYQGLWDCTGSLSDELSFKRG DVIYILSKEYNRYGWWVGEMQGAIGLVPKAYLMEMYDI hide sequence

RefSeq Acc Id:	XP_006236539 ⟸ XM_006236477
- Peptide Label:	isoform X1
- UniProtKB:	Q920G0 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MPNPGSTSSPGSIPEEIRNLLADVETFVADTLKGENLSKKAKEKRDSLIKKIKDVKSVYPQEFQ DKGDAEEGDEYDDPFAGPPDTISLASERYDKDDDGPSDGNQFPPIAAQDLSFVIKAGYLEKRRK DHSFLGFEWQKRWCALSKTVFYYYGSDKDKQQKGEFAIEGYDVRMNNTLRKDAKKDCCFEICAP DKRIYQFTAASPKDAEEWVQQLKFILQDMGSDVIPEDEDEKGDLYDDVDHPVPVSSPQRSQPID DEIYEELPEEEEDTASVKMDEQGKGSRDSVQHPSGDKSTDYANFYQGLWDCTGSLSDELSFKRG DVIYILSKEYNRYGWWVGEMQGAIGLVPKAYLMEMYDI hide sequence

RefSeq Acc Id:	XP_017447900 ⟸ XM_017592411
- Peptide Label:	isoform X2
- Sequence:	show sequence MNNTLRKDAKKDCCFEICAPDKRIYQFTAASPKDAEEWVQQLKFILQDMGSDVIPEDEDEKGDL YDDVDHPVPVSSPQRSQPIDDEIYEELPEEEEDTASVKMDEQGKGSRDSVQHPSGDKSTDYANF YQGLWDCTGSLSDELSFKRGDVIYILSKEYNRYGWWVGEMQGAIGLVPKAYLMEMYDI hide sequence

RefSeq Acc Id:

ENSRNOP00000016608 ⟸ ENSRNOT00000016608

Protein Domains

PH SH3

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13693048

Promoter ID:

EPDNEW_R3573

Type:

initiation region

Name:

Skap2_1

Description:

src kinase associated phosphoprotein 2

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	81,968,802 - 81,968,862	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620159	AgrOrtholog
Ensembl Genes	ENSRNOG00000012228	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000016608	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000016608	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	2.30.29.30	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7099436	IMAGE-MGC_LOAD
InterPro	PH-like_dom_sf	UniProtKB/Swiss-Prot
	PH_domain	UniProtKB/Swiss-Prot
	SH3-like_dom_sf	UniProtKB/Swiss-Prot
	SH3_domain	UniProtKB/Swiss-Prot
	SKAP_fam	UniProtKB/Swiss-Prot
KEGG Report	rno:155183	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:91521	IMAGE-MGC_LOAD
NCBI Gene	155183	ENTREZGENE
PANTHER	PTHR15129	UniProtKB/Swiss-Prot
Pfam	PF00169	UniProtKB/Swiss-Prot
	SH3_1	UniProtKB/Swiss-Prot
PhenoGen	Skap2	PhenoGen
PRINTS	SH3DOMAIN	UniProtKB/Swiss-Prot
PROSITE	PH_DOMAIN	UniProtKB/Swiss-Prot
	SH3	UniProtKB/Swiss-Prot
SMART	SH3	UniProtKB/Swiss-Prot
	SM00233	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF50044	UniProtKB/Swiss-Prot
UniGene	Rn.162747	ENTREZGENE
UniProt	Q920G0	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-10-23	Skap2	src kinase associated phosphoprotein 2	Skap2	src family associated phosphoprotein 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-19	Skap2	src family associated phosphoprotein 2	Scap2	src family associated phosphoprotein 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-09-10	Scap2	src family associated phosphoprotein 2			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Scap2	src family associated phosphoprotein 2			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD